{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T14:13:11Z","timestamp":1768313591645,"version":"3.49.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T00:00:00Z","timestamp":1704672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T00:00:00Z","timestamp":1704672000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1007\/s00405-023-08350-w","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T15:02:22Z","timestamp":1704726142000},"page":"1819-1825","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Causal analysis between gastroesophageal reflux disease and chronic rhinosinusitis"],"prefix":"10.1007","volume":"281","author":[{"given":"Gui","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wucheng","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shenrong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingqi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5255-8610","authenticated-orcid":false,"given":"Xiaowen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,1,8]]},"reference":[{"issue":"1","key":"8350_CR1","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1038\/s41572-020-00218-1","volume":"6","author":"C Bachert","year":"2020","unstructured":"Bachert C, Marple B, Schlosser RJ, Hopkins C, Schleimer RP, Lambrecht BN, Br\u00f6ker BM, Laidlaw T, Song WJ (2020) Adult chronic rhinosinusitis. Nat Rev Dis Primers 6(1):86. https:\/\/doi.org\/10.1038\/s41572-020-00218-1","journal-title":"Nat Rev Dis Primers"},{"issue":"10209","key":"8350_CR2","doi-asserted-by":"publisher","first-page":"1638","DOI":"10.1016\/S0140-6736(19)31881-1IF:202.731Q1","volume":"394","author":"C Bachert","year":"2019","unstructured":"Bachert C, Han JK, Desrosiers M, Hellings PW, Amin N, Lee SE, Mullol J, Greos LS, Bosso JV, Laidlaw TM, Cervin AU, Maspero JF, Hopkins C, Olze H, Canonica GW, Paggiaro P, Cho SH, Fokkens WJ, Fujieda S, Zhang M et al (2019) Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials. Lancet (London, England) 394(10209):1638\u20131650. https:\/\/doi.org\/10.1016\/S0140-6736(19)31881-1IF:202.731Q1","journal-title":"Lancet (London, England)"},{"issue":"1","key":"8350_CR3","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1128\/CMR.00060-16","volume":"30","author":"M Hoggard","year":"2017","unstructured":"Hoggard M, Wagner Mackenzie B, Jain R, Taylor MW, Biswas K, Douglas RG (2017) Chronic rhinosinusitis and the evolving understanding of microbial ecology in chronic inflammatory mucosal disease. Clin Microbiol Rev 30(1):321\u2013348. https:\/\/doi.org\/10.1128\/CMR.00060-16","journal-title":"Clin Microbiol Rev"},{"key":"8350_CR4","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1177\/00034894041130s503IF:1.973Q3","volume":"193","author":"DW Kennedy","year":"2004","unstructured":"Kennedy DW (2004) Pathogenesis of chronic rhinosinusitis. Ann Otol Rhinol Laryngol 193:6\u20139. https:\/\/doi.org\/10.1177\/00034894041130s503IF:1.973Q3","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"12","key":"8350_CR5","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1080\/1744666X.2022.2128767","volume":"18","author":"JC Ceballos Cantu","year":"2022","unstructured":"Ceballos Cantu JC, Alobid I, Mullol J (2022) chronic rhinosinusitis in a population of patients with gastroesophageal reflux disease. Expert Rev Clin Immunol 18(12):1253\u20131263. https:\/\/doi.org\/10.1080\/1744666X.2022.2128767","journal-title":"Expert Rev Clin Immunol"},{"issue":"7","key":"8350_CR6","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1002\/alr.21315","volume":"4","author":"C Baguley","year":"2014","unstructured":"Baguley C, Brownlow A, Yeung K, Pratt E, Sacks R, Harvey R (2014) The fate of chronic rhinosinusitis sufferers after maximal medical therapy. Int Forum Allergy Rhinol 4(7):525\u2013532. https:\/\/doi.org\/10.1002\/alr.21315","journal-title":"Int Forum Allergy Rhinol"},{"issue":"5","key":"8350_CR7","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1097\/00005537-200405000-00004","volume":"114","author":"R Wynn","year":"2004","unstructured":"Wynn R, Har-El G (2004) Recurrence rates after endoscopic sinus surgery for massive sinus polyposis. Laryngoscope 114(5):811\u2013813. https:\/\/doi.org\/10.1097\/00005537-200405000-00004","journal-title":"Laryngoscope"},{"issue":"4","key":"8350_CR8","doi-asserted-by":"publisher","first-page":"848","DOI":"10.1016\/j.jaci.2023.01.004","volume":"151","author":"D Lal","year":"2023","unstructured":"Lal D, Brar T, Ramkumar SP, Li J, Kato A, Zhang L (2023) Genetics and epigenetics of chronic rhinosinusitis. J Allergy Clin Immunol 151(4):848\u2013868. https:\/\/doi.org\/10.1016\/j.jaci.2023.01.004","journal-title":"J Allergy Clin Immunol"},{"issue":"14","key":"8350_CR9","doi-asserted-by":"publisher","first-page":"1472","DOI":"10.1001\/jama.2021.1438","volume":"325","author":"RS Mehta","year":"2021","unstructured":"Mehta RS, Staller K, Chan AT (2021) Review of gastroesophageal reflux disease. JAMA 325(14):1472. https:\/\/doi.org\/10.1001\/jama.2021.1438","journal-title":"JAMA"},{"issue":"4","key":"8350_CR10","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1111\/j.1572-0241.2002.05598.x","volume":"97","author":"JK DiBaise","year":"2002","unstructured":"DiBaise JK, Olusola BF, Huerter JV, Quigley EM (2002) Role of GERD in chronic resistant sinusitis: a prospective, open label, pilot trial. Am J Gastroenterol 97(4):843\u2013850. https:\/\/doi.org\/10.1111\/j.1572-0241.2002.05598.x","journal-title":"Am J Gastroenterol"},{"issue":"2","key":"8350_CR11","doi-asserted-by":"publisher","first-page":"118","DOI":"10.4193\/Rhin22.297","volume":"61","author":"J Bergqvist","year":"2023","unstructured":"Bergqvist J, Bove M, Andersson A, Scholer L, Hellgren J (2023) Dose-dependent relationship between nocturnal gastroesophageal reflux and chronic rhinosinusitis in a middle-aged population: results from the SCAPIS pilot. Rhinology 61(2):118\u2013123. https:\/\/doi.org\/10.4193\/Rhin22.297","journal-title":"Rhinology"},{"issue":"3","key":"8350_CR12","doi-asserted-by":"publisher","first-page":"e70","DOI":"10.2500\/ajra.2015.29.4167","volume":"29","author":"I Bohnhorst","year":"2015","unstructured":"Bohnhorst I, Jawad S, Lange B, Kjeldsen J, Hansen JM, Kjeldsen AD (2015) Prevalence of chronic rhinosinusitis in a population of patients with gastroesophageal reflux disease. Am J Rhinol Allergy 29(3):e70\u2013e74. https:\/\/doi.org\/10.2500\/ajra.2015.29.4167","journal-title":"Am J Rhinol Allergy"},{"issue":"1","key":"8350_CR13","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1007\/s00405-011-1675-y","volume":"269","author":"EJ Katle","year":"2012","unstructured":"Katle EJ, Hart H, Kj\u00e6rgaard T, Kval\u00f8y JT, Steinsv\u00e5g SK (2012) Nose- and sinus-related quality of life and GERD. European archives of oto-rhino-laryngology: official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS): affiliated with the German Society for Oto-Rhino-Laryngology. Head Neck Surg 269(1):121\u2013125. https:\/\/doi.org\/10.1007\/s00405-011-1675-y","journal-title":"Head Neck Surg"},{"issue":"1","key":"8350_CR14","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1186\/s12890-020-01364-8","volume":"21","author":"E Finocchio","year":"2021","unstructured":"Finocchio E, Locatelli F, Sanna F, Vesentini R, Marchetti P, Spiteri G, Antonicelli L, Battaglia S, Bono R, Corsico AG, Ferrari M, Murgia N, Pirina P, Olivieri M, Verlato G (2021) Gastritis and gastroesophageal reflux disease are strongly associated with non-allergic nasal disorders. BMC Pulm Med 21(1):53. https:\/\/doi.org\/10.1186\/s12890-020-01364-8","journal-title":"BMC Pulm Med"},{"issue":"4","key":"8350_CR15","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1111\/coa.14047","volume":"48","author":"JR Lechien","year":"2023","unstructured":"Lechien JR, Saussez S, Hopkins C (2023) Association between laryngopharyngeal reflux, gastroesophageal reflux and recalcitrant chronic rhinosinusitis: a systematic review. Clin Otolaryngol 48(4):501\u2013514. https:\/\/doi.org\/10.1111\/coa.14047","journal-title":"Clin Otolaryngol"},{"issue":"3","key":"8350_CR16","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1016\/j.bjorl.2016.05.012","volume":"83","author":"GCP Sella","year":"2017","unstructured":"Sella GCP, Tamashiro E, Anselmo-Lima WT, Valera FCP (2017) Relation between chronic rhinosinusitis and gastroesophageal reflux in adults: systematic review. Braz J Otorhinolaryngol 83(3):356\u2013363. https:\/\/doi.org\/10.1016\/j.bjorl.2016.05.012","journal-title":"Braz J Otorhinolaryngol"},{"issue":"1","key":"8350_CR17","doi-asserted-by":"publisher","first-page":"3","DOI":"10.4193\/Rhino16.177","volume":"55","author":"SR Leason","year":"2017","unstructured":"Leason SR, Barham HP, Oakley G, Rimmer J, DelGaudio JM, Christensen JM, Sacks R, Harvey RJ (2017) Association of gastro-oesophageal reflux and chronic rhinosinusitis: systematic review and meta-analysis. Rhinology 55(1):3\u201316. https:\/\/doi.org\/10.4193\/Rhino16.177","journal-title":"Rhinology"},{"issue":"2","key":"8350_CR18","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1007\/s11882-013-0340-5","volume":"13","author":"EJ Katle","year":"2013","unstructured":"Katle EJ, Hatlebakk JG, Steinsv\u00e5g S (2013) Gastroesophageal reflux and rhinosinusitis. Curr Allergy Asthma Rep 13(2):218\u2013223. https:\/\/doi.org\/10.1007\/s11882-013-0340-5","journal-title":"Curr Allergy Asthma Rep"},{"issue":"1","key":"8350_CR19","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1097\/MOO.0b013e32834e8f11","volume":"20","author":"BC Hanna","year":"2012","unstructured":"Hanna BC, Wormald PJ (2012) Gastroesophageal reflux and chronic rhinosinusitis. Curr Opin Otolaryngol Head Neck Surg 20(1):15\u201318. https:\/\/doi.org\/10.1097\/MOO.0b013e32834e8f11","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"issue":"1","key":"8350_CR20","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1093\/ije\/dyh132","volume":"33","author":"GD Smith","year":"2004","unstructured":"Smith GD, Ebrahim S (2004) Mendelian randomization: prospects, potentials, and limitations. Int J Epidemiol 33(1):30\u201342. https:\/\/doi.org\/10.1093\/ije\/dyh132","journal-title":"Int J Epidemiol"},{"issue":"2","key":"8350_CR21","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1164\/rccm.202205-0951OC","volume":"207","author":"K Ahn","year":"2023","unstructured":"Ahn K, Penn RB, Rattan S, Panettieri RA Jr, Voight BF, An SS (2023) Mendelian randomization analysis reveals a complex genetic interplay among atopic dermatitis, asthma, and gastroesophageal reflux disease. Am J Respir Crit Care Med 207(2):130\u2013137. https:\/\/doi.org\/10.1164\/rccm.202205-0951OC","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"8350_CR22","doi-asserted-by":"publisher","first-page":"2201585","DOI":"10.1183\/13993003.01585-2022","volume":"61","author":"CJ Reynolds","year":"2023","unstructured":"Reynolds CJ, Del Greco MF, Allen RJ, Flores C, Jenkins RG, Maher TM, Molyneaux PL, Noth I, Oldham JM, Wain LV, An J, Ong JS, MacGregor S, Yates TA, Cullinan P, Minelli C (2023) The causal relationship between gastro-oesophageal reflux disease and idiopathic pulmonary fibrosis: a bidirectional two-sample Mendelian randomisation study. Eur Respir J 61(5):2201585. https:\/\/doi.org\/10.1183\/13993003.01585-2022","journal-title":"Eur Respir J"},{"issue":"24","key":"8350_CR23","doi-asserted-by":"publisher","first-page":"4275","DOI":"10.1093\/hmg\/ddac162","volume":"31","author":"X Sun","year":"2022","unstructured":"Sun X, Chen L, Zheng L (2022) A Mendelian randomization study to assess the genetic liability of gastroesophageal reflux disease for cardiovascular diseases and risk factors. Hum Mol Genet 31(24):4275\u20134285. https:\/\/doi.org\/10.1093\/hmg\/ddac162","journal-title":"Hum Mol Genet"},{"issue":"6","key":"8350_CR24","doi-asserted-by":"publisher","first-page":"2785","DOI":"10.1007\/s00405-022-07798-6","volume":"280","author":"Z Zhang","year":"2023","unstructured":"Zhang Z, Li G, Yu L, Jiang J, Li R, Zhou S, Jiang Y (2023) Causal relationships between potential risk factors and chronic rhinosinusitis: a bidirectional two-sample Mendelian randomization study. Eur arch Oto-rhino-laryngol 280(6):2785\u20132793. https:\/\/doi.org\/10.1007\/s00405-022-07798-6","journal-title":"Eur arch Oto-rhino-laryngol"},{"issue":"16","key":"8350_CR25","doi-asserted-by":"publisher","first-page":"1614","DOI":"10.1001\/jama.2021.18236","volume":"326","author":"VW Skrivankova","year":"2021","unstructured":"Skrivankova VW, Richmond RC, Woolf BAR, Yarmolinsky J, Davies NM, Swanson SA, VanderWeele TJ, Higgins JPT, Timpson NJ, Dimou N, Langenberg C, Golub RM, Loder EW, Gallo V, Tybjaerg-Hansen A, Davey Smith G, Egger M, Richards JB (2021) Strengthening the reporting of observational studies in epidemiology using mendelian randomization: The STROBE-MR Statement. JAMA 326(16):1614\u20131621. https:\/\/doi.org\/10.1001\/jama.2021.18236","journal-title":"JAMA"},{"issue":"4","key":"8350_CR26","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1002\/gepi.21965","volume":"40","author":"J Bowden","year":"2016","unstructured":"Bowden J, Davey Smith G, Haycock PC, Burgess S (2016) Consistent estimation in mendelian randomization with some invalid instruments using a weighted median estimator. Genet Epidemiol 40(4):304\u2013314. https:\/\/doi.org\/10.1002\/gepi.21965","journal-title":"Genet Epidemiol"},{"issue":"2","key":"8350_CR27","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1093\/ije\/dyv080","volume":"44","author":"J Bowden","year":"2015","unstructured":"Bowden J, Davey Smith G, Burgess S (2015) Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression. Int J Epidemiol 44(2):512\u2013525. https:\/\/doi.org\/10.1093\/ije\/dyv080","journal-title":"Int J Epidemiol"},{"issue":"R1","key":"8350_CR28","doi-asserted-by":"publisher","first-page":"R89","DOI":"10.1093\/hmg\/ddu328","volume":"23","author":"G Davey Smith","year":"2014","unstructured":"Davey Smith G, Hemani G (2014) Mendelian randomization: genetic anchors for causal inference in epidemiological studies. Hum Mol Genet 23(R1):R89\u2013R98. https:\/\/doi.org\/10.1093\/hmg\/ddu328","journal-title":"Hum Mol Genet"},{"issue":"5","key":"8350_CR29","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1007\/s10654-021-00757-1","volume":"36","author":"AR Carter","year":"2021","unstructured":"Carter AR, Sanderson E, Hammerton G, Richmond RC, Davey Smith G, Heron J, Taylor AE, Davies NM, Howe LD (2021) Mendelian randomisation for mediation analysis: current methods and challenges for implementation. Eur J Epidemiol 36(5):465\u2013478. https:\/\/doi.org\/10.1007\/s10654-021-00757-1","journal-title":"Eur J Epidemiol"},{"issue":"11","key":"8350_CR30","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1007081IF:6.020Q1","volume":"13","author":"G Hemani","year":"2017","unstructured":"Hemani G, Tilling K, Davey Smith G (2017) Orienting the causal relationship between imprecisely measured traits using GWAS summary data. PLoS Genet 13(11):e1007081. https:\/\/doi.org\/10.1371\/journal.pgen.1007081IF:6.020Q1","journal-title":"PLoS Genet"},{"issue":"12","key":"8350_CR31","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.7326\/0003-4819-129-12-199812150-00029","volume":"129","author":"JK DiBaise","year":"1998","unstructured":"DiBaise JK, Huerter JV, Quigley EM (1998) Sinusitis and gastroesophageal reflux disease. Ann Intern Med 129(12):1078. https:\/\/doi.org\/10.7326\/0003-4819-129-12-199812150-00029","journal-title":"Ann Intern Med"},{"issue":"5","key":"8350_CR32","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1016\/j.otc.2012.06.004","volume":"45","author":"M Lupa","year":"2012","unstructured":"Lupa M, DelGaudio JM (2012) Evidence-based practice: reflux in sinusitis. Otolaryngol Clin North Am 45(5):983\u2013992. https:\/\/doi.org\/10.1016\/j.otc.2012.06.004","journal-title":"Otolaryngol Clin North Am"},{"issue":"1","key":"8350_CR33","doi-asserted-by":"publisher","first-page":"11","DOI":"10.4193\/Rhino10.054","volume":"49","author":"EP Flook","year":"2011","unstructured":"Flook EP, Kumar BN (2011) Is there evidence to link acid reflux with chronic sinusitis or any nasal symptoms? A review of the evidence. Rhinology 49(1):11\u201316. https:\/\/doi.org\/10.4193\/Rhino10.054","journal-title":"Rhinology"},{"issue":"6","key":"8350_CR34","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1111\/all.12615","volume":"70","author":"L Schi\u00f6ler","year":"2015","unstructured":"Schi\u00f6ler L, Ruth M, J\u00f5gi R, Gislason T, Storaas T, Janson C, Forsberg B, Sigsgaard T, Tor\u00e9n K, Hellgren J (2015) Nocturnal GERD\u2014a risk factor for rhinitis\/rhinosinusitis: the RHINE study. Allergy 70(6):697\u2013702. https:\/\/doi.org\/10.1111\/all.12615","journal-title":"Allergy"},{"issue":"39","key":"8350_CR35","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000001642","volume":"94","author":"YH Lin","year":"2015","unstructured":"Lin YH, Chang TS, Yao YC, Li YC (2015) Increased risk of chronic sinusitis in adults with gastroesophgeal reflux disease: a nationwide population-based cohort study. Medicine 94(39):e1642. https:\/\/doi.org\/10.1097\/MD.0000000000001642","journal-title":"Medicine"},{"issue":"Suppl 1","key":"8350_CR36","doi-asserted-by":"publisher","first-page":"S22","DOI":"10.1002\/alr.21695","volume":"6","author":"RR Orlandi","year":"2016","unstructured":"Orlandi RR, Kingdom TT, Hwang PH, Smith TL, Alt JA, Baroody FM, Batra PS, Bernal-Sprekelsen M, Bhattacharyya N, Chandra RK, Chiu A, Citardi MJ, Cohen NA, DelGaudio J, Desrosiers M, Dhong HJ, Douglas R, Ferguson B, Fokkens WJ, Georgalas C et al (2016) International consensus statement on allergy and rhinology: rhinosinusitis. Int Forum Allergy Rhinol 6(Suppl 1):S22\u2013S209. https:\/\/doi.org\/10.1002\/alr.21695","journal-title":"Int Forum Allergy Rhinol"},{"issue":"9","key":"8350_CR37","doi-asserted-by":"publisher","first-page":"1582","DOI":"10.1097\/00005537-200409000-00015","volume":"114","author":"IW Wong","year":"2004","unstructured":"Wong IW, Omari TI, Myers JC, Rees G, Nair SB, Jamieson GG, Wormald PJ (2004) Nasopharyngeal pH monitoring in chronic sinusitis patients using a novel four channel probe. Laryngoscope 114(9):1582\u20131585. https:\/\/doi.org\/10.1097\/00005537-200409000-00015","journal-title":"Laryngoscope"},{"issue":"1","key":"8350_CR38","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1186\/s13223-022-00739-2","volume":"18","author":"T Pongdee","year":"2022","unstructured":"Pongdee T, Bielinski SJ, Decker PA, Kita H, Larson NB (2022) White blood cells and chronic rhinosinusitis: a Mendelian randomization study. Allergy Asthma Clin Immunol 18(1):98. https:\/\/doi.org\/10.1186\/s13223-022-00739-2","journal-title":"Allergy Asthma Clin Immunol"},{"issue":"2","key":"8350_CR39","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1007\/s12016-018-8701-4","volume":"57","author":"EJ Hait","year":"2019","unstructured":"Hait EJ, McDonald DR (2019) Impact of gastroesophageal reflux disease on mucosal immunity and atopic disorders. Clin Rev Allergy Immunol 57(2):213\u2013225. https:\/\/doi.org\/10.1007\/s12016-018-8701-4","journal-title":"Clin Rev Allergy Immunol"},{"issue":"4","key":"8350_CR40","doi-asserted-by":"publisher","first-page":"255","DOI":"10.2500\/ajra.2010.24.3490","volume":"24","author":"IW Wong","year":"2010","unstructured":"Wong IW, Rees G, Greiff L, Myers JC, Jamieson GG, Wormald PJ (2010) Gastroesophageal reflux disease and chronic sinusitis: in search of an esophageal-nasal reflex. Am J Rhinol Allergy 24(4):255\u2013259. https:\/\/doi.org\/10.2500\/ajra.2010.24.3490","journal-title":"Am J Rhinol Allergy"},{"issue":"9","key":"8350_CR41","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1097\/00005537-200309000-00027","volume":"113","author":"S Morinaka","year":"2003","unstructured":"Morinaka S, Ichimiya M, Nakamura H (2003) Detection of Helicobacter pylori in nasal and maxillary sinus specimens from patients with chronic sinusitis. Laryngoscope 113(9):1557\u20131563. https:\/\/doi.org\/10.1097\/00005537-200309000-00027","journal-title":"Laryngoscope"},{"issue":"2","key":"8350_CR42","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1016\/j.anai.2016.05.018","volume":"117","author":"M Mahdavinia","year":"2016","unstructured":"Mahdavinia M, Bishehsari F, Hayat W, Codispoti CD, Sarrafi S, Husain I, Mehta A, Benhammuda M, Tobin MC, Bandi S, LoSavio PS, Jeffe JS, Palmisano EL, Schleimer RP, Batra PS (2016) Prevalence of allergic rhinitis and asthma in patients with chronic rhinosinusitis and gastroesophageal reflux disease. Ann Allergy asthma Immunol 117(2):158-162.e1. https:\/\/doi.org\/10.1016\/j.anai.2016.05.018","journal-title":"Ann Allergy asthma Immunol"},{"key":"8350_CR43","doi-asserted-by":"publisher","first-page":"1046989","DOI":"10.3389\/fgene.2022.1046989","volume":"13","author":"L Shu","year":"2022","unstructured":"Shu L, Tong X (2022) Exploring the causal relationship between gastroesophageal reflux and oral lesions: a mendelian randomization study. Front Genet 13:1046989. https:\/\/doi.org\/10.3389\/fgene.2022.1046989","journal-title":"Front Genet"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-023-08350-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-023-08350-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-023-08350-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T12:07:39Z","timestamp":1710504459000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-023-08350-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,8]]},"references-count":43,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["8350"],"URL":"https:\/\/doi.org\/10.1007\/s00405-023-08350-w","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,8]]},"assertion":[{"value":"12 August 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 November 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 January 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"No ethical clearance was required for this study, as no patients were involved in the formulation of the research question or outcome measures. Only secondary analysis was performed using published GWAS summary statistics available in the public domain. All authors have viewed and agreed to the submission.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}