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It is thought that desaturation due to apnea\u2013hypopnea attacks in OSAS patients activates inflammatory pathways. In this study, we aimed to reveal the relationship between inflammation parameters Systemic immune inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratios (PLR) severity of OSAS in patients who underwent polysomnography in our hospital\u2019s sleep laboratory.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We grouped our 171 patients who were followed up in our sleep laboratory with the diagnosis of OSAS according to their AHI values. We evaluated the correlation of SII, NLR, and PLR values obtained from the complete blood tests of our patients with OSAS diagnosis and OSAS severity.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The mean NLR, PLR and SII values of patients with OSAS were statistically significantly higher than those without OSAS (p\u2009&lt;\u20090.05). A positive correlation of 18% was found between the presence of OSAS and the SII value (p\u2009=\u20090.016). No statistically significant difference was found when comparing OSAS severity and NLR, PLR and SII values (p\u2009&gt;\u20090.05).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>We observed that SII, NLR and PLR parameters, which are rapidly assessable systemic inflammation markers of this process, were independently associated in patients diagnosed with OSAS and that there was no change in SII, NLR, and PLR parameters with OSAS severity.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00405-024-08729-3","type":"journal-article","created":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T15:13:35Z","timestamp":1716045215000},"page":"5007-5013","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Is there a relationship between the severity of obstructive sleep apnea syndrome and the systemic immune inflammation index?"],"prefix":"10.1007","volume":"281","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2422-9470","authenticated-orcid":false,"given":"Meltem Karacan","family":"G\u00f6len","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7247-6970","authenticated-orcid":false,"given":"\u015eaziye Melike","family":"I\u015f\u0131k","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5936-5512","authenticated-orcid":false,"given":"Veysel","family":"Ar\u0131kan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,18]]},"reference":[{"issue":"3","key":"8729_CR1","doi-asserted-by":"publisher","first-page":"263","DOI":"10.5664\/jcsm.27497","volume":"5","author":"LJ Epstein","year":"2009","unstructured":"Epstein LJ, Kristo D, Strollo PJ Jr, Friedman N, Malhotra A, Patil SP, Ramar K, Rogers R, Schwab RJ, Weaver EM, Weinstein MD, Adult Obstructive Sleep Apnea Task Force of the American Academy of Sleep Medicine (2009) Clinical guidelines for the evaluation, management and long-term care of obstructive sleep apnea in adults. 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