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Patients were randomly allocated into 2 groups, cartilage tympanoplasty group (<jats:italic>n<\/jats:italic>\u2009=\u200977) and platelet rich fibrin (PRF) augmented tympanoplasty group (<jats:italic>n<\/jats:italic>\u2009=\u200979). Graft take rates, hearing outcomes, operative time, and postoperative complications were documented and compared.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Graft take rate was 96.1% in the cartilage group and 93.7% PRF group with no statistically significant difference. Operative time was significantly longer in the cartilage group. No differences in the hearing outcomes and postoperative complications were reported.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Application of PRF on the fascia in tympanoplasty promotes healing of the tympanic membrane. PRF is safe, cheap, readily available, and easily prepared and applied. 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