{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T05:09:28Z","timestamp":1785474568544,"version":"3.56.0"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T00:00:00Z","timestamp":1723248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T00:00:00Z","timestamp":1723248000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100007397","name":"Charles University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>Resection of the vestibular schwannoma causes acute peripheral vestibular loss. The process of central compensation starts immediately afterward. The rehabilitation goal is to support this process and restore the quality of life.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Materials and methods<\/jats:title>\n            <jats:p>In this prospective single-center study, 67 consecutive patients underwent vestibular schwannoma resection (40 females, mean age 52\u2009\u00b1\u200912 years). The patients were divided into three groups: the prehabilitation with intratympanic gentamicin group, the virtual reality group (optokinetic stimulation via virtual reality goggles in the first ten days after the surgery), and the control group. All patients were examined with objective methods and completed questionnaires before the prehabilitation, before the surgery, at the hospital discharge, and after three months.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Intratympanic gentamicin prehabilitation leads ipsilaterally to a significant aVOR reduction in all semicircular canals (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.050), the increase of the unilateral weakness in air calorics (<jats:italic>p<\/jats:italic>\u2009=\u20090.026), and loss of cVEMPs responses (<jats:italic>p<\/jats:italic>\u2009=\u20090.017). Prehabilitation and postoperative exposure to virtual reality scenes improved the patient\u2019s perception of vertigo problems according to Dizziness Handicap Inventory (<jats:italic>p<\/jats:italic>\u2009=\u20090.039 and <jats:italic>p<\/jats:italic>\u2009=\u20090.076, respectively). These findings conform with the optokinetic testing results, which showed higher slow phase velocities at higher speeds (40\u00a0deg\/s) in both targeted groups compared to the control group.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Preoperative intratympanic gentamicin positively affects peripheral vestibular function, influencing balance perception after VS resection. In long-term follow-up, prehabilitation and postoperative exposure to virtual reality improve patients\u2019 quality of life in the field of vertigo problems.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00405-024-08891-8","type":"journal-article","created":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T21:01:46Z","timestamp":1723323706000},"page":"79-89","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The comparison between intratympanic gentamicin prehabilitation and postoperative virtual reality exposure to standard vestibular training in patients with vestibular schwannoma"],"prefix":"10.1007","volume":"282","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3283-0503","authenticated-orcid":false,"given":"Mark\u00e9ta","family":"Bonaventurov\u00e1","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1121-9836","authenticated-orcid":false,"given":"Zuzana","family":"Balatkov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4819-9069","authenticated-orcid":false,"given":"Kv\u011btoslav","family":"\u010cerven\u00fd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6583-0836","authenticated-orcid":false,"given":"Rudolf","family":"\u010cern\u00fd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1754-7737","authenticated-orcid":false,"given":"Veronika","family":"Band\u00farov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6089-0071","authenticated-orcid":false,"given":"Vladim\u00edr","family":"Kouck\u00fd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1961-3359","authenticated-orcid":false,"given":"Lenka","family":"Peterkov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4243-9727","authenticated-orcid":false,"given":"Zden\u011bk","family":"F\u00edk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4106-5217","authenticated-orcid":false,"given":"Martin","family":"Komarc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7488-1603","authenticated-orcid":false,"given":"Eva","family":"Mr\u00e1zkov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3710-4455","authenticated-orcid":false,"given":"Jan","family":"Plz\u00e1k","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6062-6820","authenticated-orcid":false,"given":"Zden\u011bk","family":"\u010cada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,10]]},"reference":[{"issue":"1","key":"8891_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1215\/S1522851704001097","volume":"8","author":"JM Propp","year":"2006","unstructured":"Propp JM, McCarthy BJ, Davis FG, Preston-Martin S (2006) Descriptive epidemiology of vestibular schwannomas. Neuro Oncol 8(1):1\u201311. https:\/\/doi.org\/10.1215\/S1522851704001097","journal-title":"Neuro Oncol"},{"issue":"1","key":"8891_CR2","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1177\/0194599819835495","volume":"161","author":"S Torres Maldonado","year":"2019","unstructured":"Torres Maldonado S, Naples JG, Fathy R et al (2019) Recent trends in vestibular Schwannoma Management: an 11-Year analysis of the National Cancer Database. Otolaryngol - Head Neck Surg (United States) 161(1):137\u2013143. https:\/\/doi.org\/10.1177\/0194599819835495","journal-title":"Otolaryngol - Head Neck Surg (United States)"},{"issue":"2","key":"8891_CR3","first-page":"1","volume":"14","author":"F Lui","year":"2017","unstructured":"Lui F, Foris L, Willner K, Tadi P (2017) Central Vertigo. J Int Comm Radiat Units Meas 14(2):1\u2013160","journal-title":"J Int Comm Radiat Units Meas"},{"key":"8891_CR4","doi-asserted-by":"publisher","unstructured":"Deveze A, Bernard-Demanze L, Xavier F, Lavieille JP, Elziere M Vestibular compensation and vestibular rehabilitation. Current concepts and new trends. Neurophysiol Clin 2014:49\u201357. https:\/\/doi.org\/10.1016\/j.neucli.2013.10.138","DOI":"10.1016\/j.neucli.2013.10.138"},{"key":"8891_CR5","first-page":"91","volume":"4","author":"Z Balatkova","year":"2018","unstructured":"Balatkova Z, Cerny R, Fik Z et al (2018) Faktory ovliv\u0148uj\u00edc\u00ed vestibul\u00e1rn\u00ed kompenzaci u pacient\u016f po operaci vestibul\u00e1rn\u00edho schwannomu. Otorinolaryngol Foniatr 4:91\u201394","journal-title":"Otorinolaryngol Foniatr"},{"key":"8891_CR6","doi-asserted-by":"publisher","unstructured":"Bonaventurova M, Cada Z, Koucky V et al Vestibular rehabilitation in patients after vestibular schwannoma surgery. \u010cesk\u00e1 a Slovensk\u00e1 Neurologie a Neurochirurgie. https:\/\/doi.org\/10.48095\/cccsnn2023114","DOI":"10.48095\/cccsnn2023114"},{"issue":"14","key":"8891_CR7","doi-asserted-by":"publisher","first-page":"1134","DOI":"10.1212\/WNL.0B013E3181BACF85","volume":"73","author":"HG MacDougall","year":"2009","unstructured":"MacDougall HG, Weber KP, McGarvie LA, Halmagyi GM, Curthoys IS (2009) The video head impulse test. Neurology 73(14):1134\u20131141. https:\/\/doi.org\/10.1212\/WNL.0B013E3181BACF85","journal-title":"Neurology"},{"key":"8891_CR8","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/J.CNP.2019.01.005","volume":"4","author":"SM Rosengren","year":"2019","unstructured":"Rosengren SM, Colebatch JG, Young AS, Govender S, Welgampola MS (2019) Vestibular evoked myogenic potentials in practice: methods, pitfalls and clinical applications. Clin Neurophysiol Pract 4:47\u201368. https:\/\/doi.org\/10.1016\/J.CNP.2019.01.005","journal-title":"Clin Neurophysiol Pract"},{"issue":"3","key":"8891_CR9","doi-asserted-by":"publisher","first-page":"506","DOI":"10.3171\/JNS.1998.88.3.0506","volume":"88","author":"WT Koos","year":"1998","unstructured":"Koos WT, Day JD, Matula C, Levy DI (1998) Neurotopographic considerations in the microsurgical treatment of small acoustic neurinomas. J Neurosurg 88(3):506\u2013512. https:\/\/doi.org\/10.3171\/JNS.1998.88.3.0506","journal-title":"J Neurosurg"},{"issue":"4","key":"8891_CR10","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1055\/S-0029-1241125\/ID\/16","volume":"30","author":"DL McCaslin","year":"2009","unstructured":"McCaslin DL, Jacobson GP (2009) Current role of the videonystagmography examination in the context of the multidimensional balance function test battery. Semin Hear 30(4):242\u2013252. https:\/\/doi.org\/10.1055\/S-0029-1241125\/ID\/16","journal-title":"Semin Hear"},{"key":"8891_CR11","doi-asserted-by":"publisher","unstructured":"Oussou G, Magnani C, Bargiotas I, Lamas G, Tankere F, Vidal C (2022) A New Sensitive Test using virtual reality and foam to probe postural control in vestibular patients: the unilateral Schwannoma Model. Front Neurol 13. https:\/\/doi.org\/10.3389\/FNEUR.2022.891232","DOI":"10.3389\/FNEUR.2022.891232"},{"issue":"5","key":"8891_CR12","doi-asserted-by":"publisher","first-page":"e623","DOI":"10.1097\/MAO.0000000000002600","volume":"41","author":"N West","year":"2020","unstructured":"West N, Sass H, Klokker M, Cay\u00e9-Thomasen P (2020) Video Head Impulse Test results in patients with a vestibular schwannoma-sensitivity and correlation with other vestibular system function tests, hearing acuity, and Tumor size. Otol Neurotol 41(5):e623\u2013e629. https:\/\/doi.org\/10.1097\/MAO.0000000000002600","journal-title":"Otol Neurotol"},{"issue":"5","key":"8891_CR13","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1007\/S00405-014-3397-4\/TABLES\/2","volume":"272","author":"SL Bell","year":"2015","unstructured":"Bell SL, Barker F, Heselton H, MacKenzie E, Dewhurst D, Sanderson A (2015) A study of the relationship between the video head impulse test and air calorics. Eur Arch Oto-Rhino-Laryngology 272(5):1287\u20131294. https:\/\/doi.org\/10.1007\/S00405-014-3397-4\/TABLES\/2","journal-title":"Eur Arch Oto-Rhino-Laryngology"},{"key":"8891_CR14","doi-asserted-by":"publisher","first-page":"79","DOI":"10.3389\/FNEUR.2020.00079\/BIBTEX","volume":"11","author":"JL Millar","year":"2020","unstructured":"Millar JL, Gimmon Y, Roberts D, Schubert MC (2020) Improvement after vestibular Rehabilitation not explained by Improved Passive VOR Gain. Front Neurol 11:79. https:\/\/doi.org\/10.3389\/FNEUR.2020.00079\/BIBTEX","journal-title":"Front Neurol"},{"issue":"2","key":"8891_CR15","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1001\/ARCHOTOL.1942.03760020076011","volume":"36","author":"D Macfarlan","year":"1942","unstructured":"Macfarlan D (1942) Hearing aids accepted by the council on physical therapy, American medical association. Arch Otolaryngol 36(2):240\u2013242. https:\/\/doi.org\/10.1001\/ARCHOTOL.1942.03760020076011","journal-title":"Arch Otolaryngol"},{"issue":"8","key":"8891_CR16","doi-asserted-by":"publisher","first-page":"1646","DOI":"10.1002\/LARY.20988","volume":"120","author":"BT Shaffer","year":"2010","unstructured":"Shaffer BT, Cohen MS, Bigelow DC, Ruckenstein MJ (2010) Validation of a disease-specific quality-of-life instrument for acoustic neuroma. Laryngoscope 120(8):1646\u20131654. https:\/\/doi.org\/10.1002\/LARY.20988","journal-title":"Laryngoscope"},{"issue":"4","key":"8891_CR17","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1001\/ARCHOTOL.1990.01870040046011","volume":"116","author":"GP Jacobson","year":"1990","unstructured":"Jacobson GP, Newman CW (1990) The development of the Dizziness Handicap Inventory. Arch Otolaryngol Head Neck Surg 116(4):424\u2013427. https:\/\/doi.org\/10.1001\/ARCHOTOL.1990.01870040046011","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"10","key":"8891_CR18","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1001\/ARCHINTE.166.10.1092","volume":"166","author":"RL Spitzer","year":"2006","unstructured":"Spitzer RL, Kroenke K, Williams JBW, L\u00f6we B (2006) A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med 166(10):1092\u20131097. https:\/\/doi.org\/10.1001\/ARCHINTE.166.10.1092","journal-title":"Arch Intern Med"},{"issue":"1","key":"8891_CR19","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1001\/ARCHPSYC.1965.01720310065008","volume":"12","author":"WWK Zung","year":"1965","unstructured":"Zung WWK (1965) A self-rating depression scale. Arch Gen Psychiatry 12(1):63\u201370. https:\/\/doi.org\/10.1001\/ARCHPSYC.1965.01720310065008","journal-title":"Arch Gen Psychiatry"},{"key":"8891_CR20","doi-asserted-by":"publisher","unstructured":"\u010cada Z, Balatkov\u00e1 Z, Chovanec M et al (2016) Vertigo Perception and Quality of Life in patients after Surgical treatment of vestibular schwannoma with pretreatment prehabituation by Chemical vestibular ablation. Biomed Res Int 2016. https:\/\/doi.org\/10.1155\/2016\/6767216","DOI":"10.1155\/2016\/6767216"},{"issue":"4","key":"8891_CR21","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1002\/SIM.4067","volume":"30","author":"IR White","year":"2011","unstructured":"White IR, Royston P, Wood AM (2011) Multiple imputation using chained equations: issues and guidance for practice. Stat Med 30(4):377\u2013399. https:\/\/doi.org\/10.1002\/SIM.4067","journal-title":"Stat Med"},{"issue":"3","key":"8891_CR22","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1007\/S11121-007-0070-9\/METRICS","volume":"8","author":"JW Graham","year":"2007","unstructured":"Graham JW, Olchowski AE, Gilreath TD (2007) How many imputations are really needed? Some practical clarifications of multiple imputation theory. Prev Sci 8(3):206\u2013213. https:\/\/doi.org\/10.1007\/S11121-007-0070-9\/METRICS","journal-title":"Prev Sci"},{"issue":"3","key":"8891_CR23","doi-asserted-by":"publisher","first-page":"749","DOI":"10.2466\/PMS.2000.91.3.749","volume":"91","author":"KJ Berry","year":"2000","unstructured":"Berry KJ, Mielke PW (2000) Exact and Monte Carlo resampling procedures for the wilcoxon-Mann-Whitney and Kruskal-Wallis tests. Percept Mot Skills 91(3):749\u2013754. https:\/\/doi.org\/10.2466\/PMS.2000.91.3.749","journal-title":"Percept Mot Skills"},{"issue":"12","key":"8891_CR24","doi-asserted-by":"publisher","first-page":"2085","DOI":"10.1097\/01.mlg.0000149439.43478.24","volume":"114","author":"R Cohen-Kerem","year":"2004","unstructured":"Cohen-Kerem R, Kisilevsky V, Einarson TR, Kozer E, Koren G, Rutka JA (2004) Intratympanic gentamicin for Meniere\u2019s disease: a meta\u2010analysis. Laryngoscope 114(12):2085\u20132091. https:\/\/doi.org\/10.1097\/01.mlg.0000149439.43478.24","journal-title":"Laryngoscope"},{"issue":"7","key":"8891_CR25","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.1097\/MLG.0b013e318058a06b","volume":"117","author":"SK Plontke","year":"2007","unstructured":"Plontke SK, Mynatt R, Gill RM, Borgmann S, Salt A (2007) N. Concentration gradient along the scala tympani after local application of gentamicin to the round window membrane. Laryngoscope 117(7):1191\u20131198. https:\/\/doi.org\/10.1097\/MLG.0b013e318058a06b","journal-title":"Laryngoscope"},{"key":"8891_CR26","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.heares.2018.03.002","volume":"368","author":"AN Salt","year":"2018","unstructured":"Salt AN, Plontke S (2018) K.Pharmacokinetic principles in the inner ear: influence of drug properties on intratympanic applications. Hear Res 368:28\u201340. https:\/\/doi.org\/10.1016\/j.heares.2018.03.002","journal-title":"Hear Res"},{"key":"8891_CR27","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.heares.2016.10.003","volume":"342","author":"AN Salt","year":"2016","unstructured":"Salt AN, Hartsock JJ, Gill RM, King E, Kraus FB, Plontke SK (2016) Perilymph pharmacokinetics of locally-applied gentamicin in the guinea pig. Hear Res 342:101\u2013111. https:\/\/doi.org\/10.1016\/j.heares.2016.10.003","journal-title":"Hear Res"},{"key":"8891_CR28","doi-asserted-by":"crossref","unstructured":"Van Gompel JJ, Agazzi S, Carlson ML et al (2018) Congress of Neurological Surgeons Systematic Review and evidence-based guidelines on emerging therapies for the treatment of patients with Vestibular Schwannomas. 82:E52\u2013E54Clinical Neurosurgery","DOI":"10.1093\/neuros\/nyx516"},{"key":"8891_CR29","doi-asserted-by":"publisher","first-page":"22","DOI":"10.3389\/fneur.2021.633356","volume":"12","author":"AA Tarnutzer","year":"2021","unstructured":"Tarnutzer AA, Bockisch CJ, Buffone E, Huber AM, Wettstein VG, Weber KP (2021) Pre-habilitation before vestibular schwannoma surgery\u2014impact of Intratympanal Gentamicin Application on the Vestibulo-Ocular Reflex. Front Neurol 12:22. https:\/\/doi.org\/10.3389\/fneur.2021.633356","journal-title":"Front Neurol"},{"issue":"8","key":"8891_CR30","doi-asserted-by":"publisher","first-page":"2791","DOI":"10.1016\/J.CLINPH.2016.05.005","volume":"127","author":"AA Tarnutzer","year":"2016","unstructured":"Tarnutzer AA, Bockisch CJ, Buffone E, Weiler S, Bachmann LM, Weber KP (2016) Disease-specific sparing of the anterior semicircular canals in bilateral vestibulopathy. Clin Neurophysiol 127(8):2791\u20132801. https:\/\/doi.org\/10.1016\/J.CLINPH.2016.05.005","journal-title":"Clin Neurophysiol"},{"issue":"9","key":"8891_CR31","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1017\/S0022215123000725","volume":"137","author":"T Potdar","year":"2023","unstructured":"Potdar T, Kontorinis G (2023) Pre-habilitation with intratympanic gentamicin in vestibular schwannomas: a systematic review. J Laryngol Otol 137(9):985\u2013991. https:\/\/doi.org\/10.1017\/S0022215123000725","journal-title":"J Laryngol Otol"},{"key":"8891_CR32","unstructured":"Fuentealba Bassaletti C, van Esch BF, Jansen JC, van Benthem PPG, Hensen EF (2023) The effect of intratympanic gentamicin as a prehabilitation strategy for objective and subjective vestibular function in patients undergoing microsurgery for a unilateral vestibular schwannoma. Eur Arch Oto-Rhino-Laryngology 012345678910.1007\/s00405-023-08240-1"},{"issue":"02","key":"8891_CR33","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1055\/s-0037-1604064","volume":"22","author":"S Yeti\u015fer","year":"2018","unstructured":"Yeti\u015fer S (2018) Intratympanic gentamicin for intractable Meniere\u2019s Disease\u2013a review and analysis of audiovestibular impact. Int Archives Otorhinolaryngol 22(02):190\u2013194. https:\/\/doi.org\/10.1055\/s-0037-1604064","journal-title":"Int Archives Otorhinolaryngol"},{"issue":"10","key":"8891_CR34","doi-asserted-by":"publisher","first-page":"1812","DOI":"10.1097\/00005537-200110000-00027","volume":"111","author":"KE Brown","year":"2001","unstructured":"Brown KE, Whitney SL, Wrisley DM, Furman JM (2001) Physical therapy outcomes for persons with bilateral vestibular loss. Laryngoscope 111(10):1812\u20131817. https:\/\/doi.org\/10.1097\/00005537-200110000-00027","journal-title":"Laryngoscope"},{"issue":"3","key":"8891_CR35","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1007\/S00405-015-3561-5","volume":"273","author":"T Abboud","year":"2016","unstructured":"Abboud T, Regelsberger J, Matschke J, Jowett N, Westphal M, Dalchow C (2016) Long-term vestibulocochlear functional outcome following retro-sigmoid approach to resection of vestibular schwannoma. Eur Arch Otorhinolaryngol 273(3):719\u2013725. https:\/\/doi.org\/10.1007\/S00405-015-3561-5","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"8891_CR36","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1007\/s00415-004-0476-2","volume":"251","author":"M Pavlou","year":"2004","unstructured":"Pavlou M, Lingeswaran A, Davies RA, Gresty MA, Bronstein AM (2004) Original communication. Simulator-based rehabilitation in refractory dizziness. J Neurol 251:983\u2013995. https:\/\/doi.org\/10.1007\/s00415-004-0476-2","journal-title":"J Neurol"},{"issue":"3","key":"8891_CR37","first-page":"221","volume":"4","author":"MS Redfern","year":"1994","unstructured":"Redfern MS, Furman JM (1994) Postural sway of patients with vestibular disorders during optic flow. J Vestib Res 4(3):221\u2013230","journal-title":"J Vestib Res"},{"issue":"5","key":"8891_CR38","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1136\/JNNP.59.5.472","volume":"59","author":"AM Bronstein","year":"1995","unstructured":"Bronstein AM (1995) Visual vertigo syndrome: clinical and posturography findings. J Neurol Neurosurg Psychiatry 59(5):472\u2013476. https:\/\/doi.org\/10.1136\/JNNP.59.5.472","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"Pt 8","key":"8891_CR39","doi-asserted-by":"publisher","first-page":"1646","DOI":"10.1093\/BRAIN\/124.8.1646","volume":"124","author":"M Guerraz","year":"2001","unstructured":"Guerraz M, Yardley L, Bertholon P et al (2001) Visual vertigo: symptom assessment, spatial orientation, and postural control. Brain 124(Pt 8):1646\u20131656. https:\/\/doi.org\/10.1093\/BRAIN\/124.8.1646","journal-title":"Brain"},{"issue":"5\u20136","key":"8891_CR40","doi-asserted-by":"publisher","first-page":"273","DOI":"10.3233\/VES-120462","volume":"22","author":"M Pavlou","year":"2012","unstructured":"Pavlou M, Kanegaonkar RG, Swapp D, Bamiou DE, Slater M, Luxon LM (2012) The effect of virtual reality on visual vertigo symptoms in patients with peripheral vestibular dysfunction: a pilot study. J Vestib Res Equilib Orientat 22(5\u20136):273\u2013281. https:\/\/doi.org\/10.3233\/VES-120462","journal-title":"J Vestib Res Equilib Orientat"},{"key":"8891_CR41","doi-asserted-by":"publisher","unstructured":"Choi SY, Choi JH, Oh EH, Oh SJ, Choi KD (2021) Effect of vestibular exercise and optokinetic stimulation using virtual reality in persistent postural-perceptual dizziness. Sci Rep 11(1). https:\/\/doi.org\/10.1038\/S41598-021-93940-Z","DOI":"10.1038\/S41598-021-93940-Z"},{"issue":"2\u20133","key":"8891_CR42","doi-asserted-by":"publisher","first-page":"147","DOI":"10.3233\/VES-190660","volume":"29","author":"A Nehrujee","year":"2019","unstructured":"Nehrujee A, Vasanthan L, Lepcha A, Balasubramanian S (2019) A smartphone-based gaming system for vestibular rehabilitation: a usability study. J Vestib Res 29(2\u20133):147\u2013160. https:\/\/doi.org\/10.3233\/VES-190660","journal-title":"J Vestib Res"},{"issue":"1","key":"8891_CR43","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1186\/S40463-023-00642-9\/TABLES\/3","volume":"52","author":"A Heffernan","year":"2023","unstructured":"Heffernan A, Booth L, Fletcher R, Nunez DA (2023) Vestibular rehabilitation potential of commercially available virtual reality video games. J Otolaryngol Head Neck Surg 52(1):54. https:\/\/doi.org\/10.1186\/S40463-023-00642-9\/TABLES\/3","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"8891_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2015\/916735","volume":"2015","author":"M Bergeron","year":"2015","unstructured":"Bergeron M, Lortie CL, Guitton MJ (2015) Use of virtual reality tools for vestibular disorders Rehabilitation: a comprehensive analysis. Adv Med 2015:1\u20139. https:\/\/doi.org\/10.1155\/2015\/916735","journal-title":"Adv Med"},{"key":"8891_CR45","doi-asserted-by":"publisher","unstructured":"Lacour M Restoration of vestibular function: Basic aspects and practical advances for rehabilitation. Curr Med Res Opin 2006:1651\u20131659. https:\/\/doi.org\/10.1185\/030079906X115694","DOI":"10.1185\/030079906X115694"},{"issue":"1","key":"8891_CR46","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1055\/S-0039-3402062","volume":"40","author":"SL Whitney","year":"2020","unstructured":"Whitney SL, Sparto PJ, Furman JM (2020) Vestibular Rehabilitation and factors that can affect outcome. Semin Neurol 40(1):165\u2013172. https:\/\/doi.org\/10.1055\/S-0039-3402062","journal-title":"Semin Neurol"},{"key":"8891_CR47","doi-asserted-by":"publisher","unstructured":"Zobeiri OA, Mischler GM, King SA, Lewis RF, Cullen KE (2021) Effects of vestibular neurectomy and neural compensation on head movements in patients undergoing vestibular schwannoma resection. Sci Rep 11(1). https:\/\/doi.org\/10.1038\/S41598-020-79756-3","DOI":"10.1038\/S41598-020-79756-3"},{"issue":"4\u20135","key":"8891_CR48","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1177\/1545968318770271","volume":"32","author":"SS Paul","year":"2018","unstructured":"Paul SS, Dibble LE, Walther RG, Shelton C, Gurgel RK, Lester ME (2018) Reduced Purposeful Head Movements during Community Ambulation following unilateral vestibular loss. Neurorehabil Neural Repair 32(4\u20135):309\u2013316. https:\/\/doi.org\/10.1177\/1545968318770271","journal-title":"Neurorehabil Neural Repair"},{"key":"8891_CR49","doi-asserted-by":"publisher","unstructured":"Van Laer L, Hallemans A, Van Rompaey V, De Valck C, Van de Heyning P, Vereeck L (2022) Subjective perception of activity level: a prognostic factor for developing chronic dizziness after vestibular schwannoma resection? Front Neurol 13. https:\/\/doi.org\/10.3389\/FNEUR.2022.925801","DOI":"10.3389\/FNEUR.2022.925801"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-024-08891-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-024-08891-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-024-08891-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T19:54:50Z","timestamp":1736970890000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-024-08891-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,10]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["8891"],"URL":"https:\/\/doi.org\/10.1007\/s00405-024-08891-8","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,10]]},"assertion":[{"value":"19 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 August 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"A local ethics committee approved the study. It was performed per the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments, with patients giving their informed consent. The trial is registered with clinical study registration number NCT05578560.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical consideration"}}]}}