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PubMed, Scopus, CINAHL, and Cochrane Library databases were searched from inception to November 27, 2023. Studies of patients diagnosed with SSc and audiologic and vestibular symptoms were selected for review. Studies of non-SSc pathologies, studies without audiovestibular outcomes, and case reports (fewer than four patients) were excluded. A meta-analysis of proportions and comparison of weighted proportions was performed in MedCalc 20.217.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Thirteen studies with 414 SSc patients and 390 control patients were included. The mean\u2009\u00b1\u2009SD symptom duration was 108.5\u2009\u00b1\u200971.8 (range: 6-600) months for SSc patients. Comparison of proportions showed patients with SSc were significantly more burdened with symptoms of tinnitus (\u039434.1% [95% CI, 27.6\u201340.5]; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), vertigo (\u039432.4% [95% CI, 24.8\u201340.3]; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001), and subjective hearing loss (\u039426.0% [95% CI, 20.8\u201331.3]; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001) compared to control patients. Findings regarding vestibular testing were not meta-analyzable because of incomplete data and lack of standard reporting.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>SSc patients showed statistically significant, yet not clinically significant, worse hearing than controls. These differences, along with increased reports of subjective audiological and vestibular symptoms in patients with SSc, emphasize interdisciplinary collaboration and assessment of SSc for audiovestibular pathologies in the appropriate clinical context.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00405-024-09001-4","type":"journal-article","created":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T18:01:26Z","timestamp":1728669686000},"page":"1147-1157","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Audiovestibular symptoms in systemic sclerosis: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"282","author":[{"given":"Craig D.","family":"Salvador","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian A.","family":"Keith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celine","family":"Ward","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0664-4571","authenticated-orcid":false,"given":"Shaun A.","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamar","family":"Gordis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shreya","family":"Chidarala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Brennan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Habib","family":"Rizk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,11]]},"reference":[{"issue":"12","key":"9001_CR1","doi-asserted-by":"publisher","first-page":"2096","DOI":"10.1111\/1756-185X.13716","volume":"22","author":"L Zhong","year":"2019","unstructured":"Zhong L, Pope M, Shen Y, Hernandez JJ, Wu L (2019) Prevalence and incidence of systemic sclerosis: a systematic review and meta-analysis. 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