{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T16:12:33Z","timestamp":1771258353925,"version":"3.50.1"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:00:00Z","timestamp":1732665600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:00:00Z","timestamp":1732665600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100006447","name":"University of Zurich","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100006447","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Purpose<\/jats:title>\n            <jats:p>Different surgical techniques exist for treating cholesteatoma, such as microscopical or transcanal endoscopic ear surgery (TEES). This study aimed to compare these two techniques, focusing on quality of life.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>This retrospective single-center study included 188 patients with cholesteatoma. The primary outcome was the assessment of health-related quality of life (HRQoL) using the Zurich Chronic Middle Ear Inventory (ZCMEI-21) preoperatively, 3 and 12 months postoperatively with regard to surgical technique and intraoperative staging of the cholesteatoma (ChOLE classification). Secondary outcomes included hearing pure tone average of 0.5, 1, 2 and 4\u00a0kHz (PTA<jats:sub>4<\/jats:sub>), complications assessed 3 months postoperatively as well as recidivism within the follow-up time of 1 year postoperatively.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>A total of 28 patients underwent TEES and 160 microscopic ear surgery. The ZCMEI-21 total scores preoperatively were not significantly different between the two groups. An improvement in QoL one year postoperatively was observed in both groups to a comparable extent. The ZCMEI-21 decreased significantly (<jats:italic>p<\/jats:italic>\u2009&lt;\u00a00.01) in both groups. In the TEES group, the cholesteatoma tended to be smaller (lower ChOLE score), PTA<jats:sub>4<\/jats:sub> was better and complication rate comparable. The number of recidivisms was lower for the TEES group (1 [3.6%] vs. 31 [19.4%]).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>TEES is a valuable alternative to the traditional microscopic technique, at least for small cholesteatoma, which leads to a comparable improvement in HRQoL as the microscopic technique. The better postoperative hearing and lower rate of recidivism in the TEES group may be related to the smaller extent of the cholesteatoma.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00405-024-09097-8","type":"journal-article","created":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T04:53:22Z","timestamp":1732683202000},"page":"2275-2283","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Health-related quality of life in patients after endoscopic or microscopic cholesteatoma surgery"],"prefix":"10.1007","volume":"282","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-9897-4674","authenticated-orcid":false,"given":"Yannik","family":"Raemy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"B\u00e4chinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Peter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christof","family":"Roosli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,11,27]]},"reference":[{"issue":"6","key":"9097_CR1","first-page":"877","volume":"21","author":"A Mudry","year":"2000","unstructured":"Mudry A (2000) The history of the microscope for use in ear surgery. Otol Neurotol 21(6):877\u2013886","journal-title":"Otol Neurotol"},{"issue":"8","key":"9097_CR2","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1288\/00005537-199308000-00021","volume":"103","author":"JM Thomassin","year":"1993","unstructured":"Thomassin JM, Korchia D, Doris JMD (1993) Endoscopic-guided otosurgery in the prevention of residual cholesteatomas. Laryngoscope 103(8):939\u2013943. https:\/\/doi.org\/10.1288\/00005537-199308000-00021","journal-title":"Laryngoscope"},{"key":"9097_CR3","doi-asserted-by":"crossref","unstructured":"Stern Shavit S, Golub JS, Lustig LR (2020) The risks of being otologist, an ergonomic and occupational hazard review. Otol Neurotol 41(9):1182\u20131189.\u00a0Available: https:\/\/journals.lww.com\/otology-neurotology\/fulltext\/2020\/10000\/the_risks_of_being_otologist,_an_ergonomic_and.6.aspx","DOI":"10.1097\/MAO.0000000000002769"},{"issue":"9","key":"9097_CR4","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1001\/archoto.2012.1800","volume":"138","author":"SY Choi","year":"2012","unstructured":"Choi SY, Cho Y-S, Lee NJ, Lee J, Chung W-H, Hong SH (2012) Factors associated with quality of life after ear surgery in patients with chronic otitis media. Arch Otolaryngol Head Neck Surg 138(9):840\u2013845. https:\/\/doi.org\/10.1001\/archoto.2012.1800","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"10","key":"9097_CR5","doi-asserted-by":"publisher","first-page":"3073","DOI":"10.1007\/s00405-016-3915-7","volume":"273","author":"D B\u00e4chinger","year":"2016","unstructured":"B\u00e4chinger D, R\u00f6\u00f6sli C, Ditzen B, Huber AM (2016) Development and validation of the Zurich chronic middle ear inventory (ZCMEI-21): an electronic questionnaire for assessing quality of life in patients with chronic otitis media. Eur Arch Otorhinolaryngol 273(10):3073\u20133081. https:\/\/doi.org\/10.1007\/s00405-016-3915-7","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"1","key":"9097_CR6","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.anl.2018.05.008","volume":"46","author":"D B\u00e4chinger","year":"2019","unstructured":"B\u00e4chinger D et al (2019) Japanese translation, cross-cultural adaption and multicentre validation of the Zurich chronic middle ear inventory (ZCMEI-21-Jap). Auris Nasus Larynx 46(1):18\u201323. https:\/\/doi.org\/10.1016\/j.anl.2018.05.008","journal-title":"Auris Nasus Larynx"},{"key":"9097_CR7","doi-asserted-by":"crossref","unstructured":"Basonbul RA, Ronner EA, Kozin ED, Lee DJ, Cohen MS (2021) Systematic review of endoscopic ear surgery outcomes for pediatric cholesteatoma. Otol Neurotol 42(1):108\u2013115.\u00a0[Online]. Available: https:\/\/journals.lww.com\/otology-neurotology\/fulltext\/2021\/01000\/systematic_review_of_endoscopic_ear_surgery.23.aspx","DOI":"10.1097\/MAO.0000000000002876"},{"issue":"10","key":"9097_CR8","doi-asserted-by":"publisher","first-page":"4401","DOI":"10.1007\/s00405-023-07938-6","volume":"280","author":"I Pap","year":"2023","unstructured":"Pap I et al (2023) Quality-of-life outcomes with endoscopic and microscopic type I tympanoplasty\u2014a prospective cohort study. Eur Arch Otorhinolaryngol 280(10):4401\u20134408. https:\/\/doi.org\/10.1007\/s00405-023-07938-6","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"4","key":"9097_CR9","doi-asserted-by":"publisher","first-page":"103860","DOI":"10.1016\/j.amjoto.2023.103860","volume":"44","author":"G Iannella","year":"2023","unstructured":"Iannella G et al (2023) Endaural microscopic approach versus endoscopic transcanal approach in treatment of attic cholesteatomas. Am J Otolaryngol 44(4):103860. https:\/\/doi.org\/10.1016\/j.amjoto.2023.103860","journal-title":"Am J Otolaryngol"},{"issue":"20","key":"9097_CR10","doi-asserted-by":"publisher","first-page":"2191","DOI":"10.1001\/jama.2013.281053","volume":"310","author":"WM Association","year":"2013","unstructured":"Association WM, World Medical Association Declaration of Helsinki (2013) Ethical principles for medical research involving human subjects. JAMA 310(20):2191\u20132194. https:\/\/doi.org\/10.1001\/jama.2013.281053","journal-title":"JAMA"},{"issue":"4","key":"9097_CR11","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1007\/s00405-020-05819-w","volume":"277","author":"D B\u00e4chinger","year":"2020","unstructured":"B\u00e4chinger D, Mlynski R, Weiss NM (2020) Establishing the minimal clinically important difference (MCID) of the Zurich chronic middle ear inventory (ZCMEI-21) in patients treated for chronic middle ear disease. Eur Arch Otorhinolaryngol 277(4):1039\u20131044. https:\/\/doi.org\/10.1007\/s00405-020-05819-w","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"9097_CR12","doi-asserted-by":"crossref","unstructured":"Linder TE, Shah S, Martha AS, R\u00f6\u00f6sli C, Emmett SD (2019) Introducing the \u2018ChOLE\u2019 classification and its comparison to the EAONO\/JOS consensus classification for cholesteatoma staging. Otol Neurotol 40(1):63\u201372.\u00a0Online]. Available: https:\/\/journals.lww.com\/otology-neurotology\/fulltext\/2019\/01000\/introducing_the__chole__classification_and_its.13.aspx","DOI":"10.1097\/MAO.0000000000002039"},{"key":"9097_CR13","unstructured":"Staging System for cholesteatoma. https:\/\/app.chole.surgery. Accessed. 26 September 2024."},{"issue":"4","key":"9097_CR14","doi-asserted-by":"publisher","first-page":"547","DOI":"10.2307\/2986146","volume":"44","author":"P Royston","year":"1995","unstructured":"Royston P (1995) Remark AS R94: a remark on Algorithm AS 181: the W-test for normality. J R Stat Soc Ser C Appl Stat 44(4):547\u2013551. https:\/\/doi.org\/10.2307\/2986146","journal-title":"J R Stat Soc Ser C Appl Stat"},{"key":"9097_CR15","unstructured":"Motulsky HJ How to report the methods used for the mixed model analysis San Diego. cited 25 May 2023. https:\/\/www.graphpad.com\/guides\/prism\/latest\/statistics\/stat_how-to-report-the-methods-used.htm"},{"issue":"1","key":"9097_CR16","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1308\/rcsann.2010.92.1.81a","volume":"92","author":"U Fisch","year":"2010","unstructured":"Fisch U, May JS, Linder T (2010) Tympanoplasty, mastoidectomy, and stapes surgery. Annals Royal Coll Surg Engl 92(1):81. https:\/\/doi.org\/10.1308\/rcsann.2010.92.1.81a","journal-title":"Annals Royal Coll Surg Engl"},{"key":"9097_CR17","doi-asserted-by":"crossref","unstructured":"Minoda R, Miwa T (2019) Non-microscopic middle ear cholesteatoma surgery: a case report of a novel head-up approach. Otol Neurotol 40(6):777\u2013781.\u00a0[Online]. Available: https:\/\/journals.lww.com\/otology-neurotology\/fulltext\/2019\/07000\/non_microscopic_middle_ear_cholesteatoma_surgery_.17.aspx","DOI":"10.1097\/MAO.0000000000002276"},{"key":"9097_CR18","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-024-08820-9","author":"E Kaya","year":"2024","unstructured":"Kaya E, Kaya F, Kaya M\u0130, \u00c7akl\u0131 H, \u0130ncesulu \u015eA (2024) A study on the efficacy of combined surgery in advanced-stage congenital cholesteatoma with canal-wall-up surgery. Eur Arch Otorhinolaryngol. https:\/\/doi.org\/10.1007\/s00405-024-08820-9","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"9097_CR19","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-024-08748-0","author":"F Kostadinov","year":"2024","unstructured":"Kostadinov F, Schlegel-Wagner C, Linder T (2024) A tailored approach in cholesteatoma surgery. Eur Arch Otorhinolaryngol. https:\/\/doi.org\/10.1007\/s00405-024-08748-0","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"9097_CR20","doi-asserted-by":"crossref","unstructured":"Erfurt C, Westerhout SF, Straatman LV, Smit AL, Stokroos RJ, Thomeer HGXM (2024) Canal-wall up cholesteatoma surgery with mastoid obliteration leads to lower rates of disease recurrence without affecting hearing outcomes. Front Surg, vol. 11, [Online]. Available: https:\/\/www.frontiersin.org\/journals\/surgery\/articles\/10.3389\/fsurg.2024.1381481","DOI":"10.3389\/fsurg.2024.1381481"},{"issue":"12","key":"9097_CR21","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1007\/s00106-023-01348-0","volume":"71","author":"V Flockerzi","year":"2023","unstructured":"Flockerzi V, Schick B, Bozzato A (2023) [Experiences with endoscopic ear surgery of a German tertiary hospital for otolaryngology]. HNO 71(12):787\u2013794. https:\/\/doi.org\/10.1007\/s00106-023-01348-0","journal-title":"HNO"},{"key":"9097_CR22","doi-asserted-by":"crossref","unstructured":"L. Presutti et al., \u201cThe Impact of the Transcanal Endoscopic Approach and Mastoid Preservation on Recurrence of Primary Acquired Attic Cholesteatoma,\u201d Otology & Neurotology, vol. 39, no. 4, 2018, [Online]. Available:https:\/\/journals.lww.com\/otology-neurotology\/fulltext\/2018\/04000\/the_impact_of_the_transcanal_endoscopic_approach.12.aspx","DOI":"10.1097\/MAO.0000000000001712"},{"issue":"11","key":"9097_CR23","doi-asserted-by":"publisher","first-page":"4827","DOI":"10.1007\/s00405-023-07996-w","volume":"280","author":"B Renner","year":"2023","unstructured":"Renner B et al (2023) EAONO\/JOS classification for acquired cholesteatoma: evaluating the impact of the number of affected sites on treatment and outcomes. Eur Arch Otorhinolaryngol 280(11):4827\u20134834. https:\/\/doi.org\/10.1007\/s00405-023-07996-w","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"10","key":"9097_CR24","doi-asserted-by":"publisher","first-page":"2729","DOI":"10.1007\/s00405-020-06002-x","volume":"277","author":"NM Weiss","year":"2020","unstructured":"Weiss NM et al (2020) Mapping the ChOLE classification to hearing outcomes and disease-specific health-related quality of life. Eur Arch Otorhinolaryngol 277(10):2729\u20132738. https:\/\/doi.org\/10.1007\/s00405-020-06002-x","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"9097_CR25","doi-asserted-by":"publisher","DOI":"10.1002\/lary.31567","author":"F Simon","year":"2024","unstructured":"Simon F et al (2024) Pediatric cholesteatoma follow-up: residual and recurrence in 239 cases with over 5-year hindsight. Laryngoscope. https:\/\/doi.org\/10.1002\/lary.31567","journal-title":"Laryngoscope"},{"issue":"5","key":"9097_CR26","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1097\/MAO.0000000000004172","volume":"45","author":"AS Vesole","year":"2023","unstructured":"Vesole AS, Doyle EJ III, Sarkovics K, Gharib M, Samy RN (2023) Outcomes of soft versus bony canal wall reconstruction with mastoid obliteration. Otol Neurotol 45(5):542\u2013548","journal-title":"Otol Neurotol"},{"issue":"5","key":"9097_CR27","doi-asserted-by":"publisher","first-page":"1365","DOI":"10.1007\/s00405-020-06208-z","volume":"278","author":"D B\u00e4chinger","year":"2021","unstructured":"B\u00e4chinger D, Rrahmani A, Weiss NM, Mlynski R, Huber A, R\u00f6\u00f6sli C (2021) Evaluating hearing outcome, recidivism and complications in cholesteatoma surgery using the ChOLE classification system. Eur Arch Otorhinolaryngol 278(5):1365\u20131371. https:\/\/doi.org\/10.1007\/s00405-020-06208-z","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"1","key":"9097_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4274\/tao.2023.2022-11-6","volume":"61","author":"A Dal\u011f\u0131\u00e7","year":"2023","unstructured":"Dal\u011f\u0131\u00e7 A, Y\u0131ld\u0131r\u0131m GA, Zorlu ME, Delice O, Aysel A (2023) Total transcanal endoscopic ear surgery for Cholesteatoma. Turk Arch Otorhinolaryngol 61(1):1","journal-title":"Turk Arch Otorhinolaryngol"},{"issue":"3","key":"9097_CR29","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.otoeng.2021.02.003","volume":"73","author":"JO Mart\u00ednez","year":"2022","unstructured":"Mart\u00ednez JO, Romero FR, G\u00f3mez SS (2022) Cholesteatoma: influence of surgical technique and EAONO\/JOS stage on audiological results. Acta Otorrinolaringol (Engl Ed) 73(3):184\u2013190. https:\/\/doi.org\/10.1016\/j.otoeng.2021.02.003","journal-title":"Acta Otorrinolaringol (Engl Ed)"},{"issue":"2","key":"9097_CR30","doi-asserted-by":"publisher","first-page":"102451","DOI":"10.1016\/j.amjoto.2020.102451","volume":"42","author":"B Li","year":"2021","unstructured":"Li B, Zhou L, Wang M, Wang Y, Zou J (2021) Endoscopic versus microscopic surgery for treatment of middle ear cholesteatoma: a systematic review and meta-analysis. Am J Otolaryngol 42(2):102451. https:\/\/doi.org\/10.1016\/j.amjoto.2020.102451","journal-title":"Am J Otolaryngol"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-024-09097-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-024-09097-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-024-09097-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T05:24:14Z","timestamp":1746509054000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-024-09097-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,27]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["9097"],"URL":"https:\/\/doi.org\/10.1007\/s00405-024-09097-8","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,27]]},"assertion":[{"value":"29 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 November 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 November 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This research did not receive any specific funding from granting agencies in the public, commercial, or not-for-profit sectors.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}}]}}