{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T14:07:30Z","timestamp":1788617250761,"version":"build-2803163510"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T00:00:00Z","timestamp":1736380800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T00:00:00Z","timestamp":1736380800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1007\/s00405-024-09186-8","type":"journal-article","created":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T18:50:45Z","timestamp":1736448645000},"page":"2627-2634","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Tie or do not tie: comparing knot tying hemostasis in tonsillectomy with other methods of hemostasis. A systematic review and meta-analysis"],"prefix":"10.1007","volume":"282","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0788-2416","authenticated-orcid":false,"given":"Euan C. E. \u00d3.","family":"Math\u00fana","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5320-1015","authenticated-orcid":false,"given":"Mel","family":"Corbett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa O.","family":"Byrne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6725-4764","authenticated-orcid":false,"given":"Moustafa","family":"Aly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew G.","family":"Davey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seng-Guan","family":"Khoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,9]]},"reference":[{"issue":"2","key":"9186_CR1","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/S0030-6665(20)30509-0","volume":"20","author":"JM Curtin","year":"1987","unstructured":"Curtin JM (1987) The history of tonsil and adenoid surgery. Otolaryngol Clin North Am 20(2):415\u2013419","journal-title":"Otolaryngol Clin North Am"},{"issue":"1","key":"9186_CR2","first-page":"59","volume":"29","author":"RA McNeill","year":"1960","unstructured":"McNeill RA (1960) A history of tonsillectomy: two millenia of trauma, haemorrhage and controversy. Ulster Med J 29(1):59\u201363","journal-title":"Ulster Med J"},{"key":"9186_CR3","doi-asserted-by":"publisher","DOI":"10.1016\/j.otot.2017.08.011","author":"ZY Jiang","year":"2017","unstructured":"Jiang ZY (2017) Bleeding after tonsillectomy. Oper Tech Otolaryngol. https:\/\/doi.org\/10.1016\/j.otot.2017.08.011","journal-title":"Oper Tech Otolaryngol"},{"key":"9186_CR4","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-1283","author":"CG De Luca","year":"2015","unstructured":"De Luca CG, Pach\u00eaco-Pereira C, Aydinoz S et al (2015) Adenotonsillectomy complications: a meta-analysis. Pediatrics. https:\/\/doi.org\/10.1542\/peds.2015-1283","journal-title":"Pediatrics"},{"key":"9186_CR5","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.488","author":"Y Inuzuka","year":"2020","unstructured":"Inuzuka Y, Mizutari K, Kamide D, Sato M, Shiotani A (2020) Risk factors of post-tonsillectomy hemorrhage in adults. Laryngoscope Investig Otolaryngol. https:\/\/doi.org\/10.1002\/lio2.488","journal-title":"Laryngoscope Investig Otolaryngol"},{"key":"9186_CR6","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9610267","author":"T Hoshino","year":"2017","unstructured":"Hoshino T, Tanigawa T, Yanohara G et al (2017) Effect of body mass index on Posttonsillectomy Hemorrhage. Biomed Res Int. https:\/\/doi.org\/10.1155\/2017\/9610267","journal-title":"Biomed Res Int"},{"key":"9186_CR7","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2017.08.012","author":"BP Galindo Torres","year":"2018","unstructured":"Galindo Torres BP, De Miguel GF, Whyte OJ (2018) Tonsillectomy in adults: analysis of indications and complications. Auris Nasus Larynx. https:\/\/doi.org\/10.1016\/j.anl.2017.08.012","journal-title":"Auris Nasus Larynx"},{"key":"9186_CR8","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2014.02.007","author":"R Ikoma","year":"2014","unstructured":"Ikoma R, Sakane S, Niwa K, Kanetaka S, Kawano T, Oridate N (2014) Risk factors for post-tonsillectomy hemorrhage. Auris Nasus Larynx. https:\/\/doi.org\/10.1016\/j.anl.2014.02.007","journal-title":"Auris Nasus Larynx"},{"key":"9186_CR9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1989.tb00397.x","author":"JJ Phillipps","year":"1989","unstructured":"Phillipps JJ, Thornton ARD (1989) Tonsillectomy haemostasis: diathermy or ligation. Clin Otolaryngol Allied Sci. https:\/\/doi.org\/10.1111\/j.1365-2273.1989.tb00397.x","journal-title":"Clin Otolaryngol Allied Sci"},{"key":"9186_CR10","doi-asserted-by":"publisher","unstructured":"Improving the quality of health care for mental and substance-use conditions. 2006. https:\/\/doi.org\/10.17226\/11470","DOI":"10.17226\/11470"},{"key":"9186_CR11","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-997520","author":"H Feldmann","year":"1997","unstructured":"Feldmann H (1997) 2000 years history of tonsillectomy. pictures from the history of otorhinolaryngology, highlighted by exhibits of the deutsche medizinhistorische museum in ingol-stadt. Laryngorhinootologie. https:\/\/doi.org\/10.1055\/s-2007-997520","journal-title":"Laryngorhinootologie"},{"key":"9186_CR12","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1962.00740040131009","author":"FR Haase","year":"1962","unstructured":"Haase FR, Noguera JT (1962) Hemostasis in tonsillectomy by electrocautery. Arch Otolaryngol. https:\/\/doi.org\/10.1001\/archotol.1962.00740040131009","journal-title":"Arch Otolaryngol"},{"key":"9186_CR13","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1962.00740040133010","author":"F Johnson","year":"1962","unstructured":"Johnson F (1962) Electrocautery in Tonsil and Adenoid Surgery. Archives of Otolaryngol. https:\/\/doi.org\/10.1001\/archotol.1962.00740040133010","journal-title":"Archives of Otolaryngol"},{"key":"9186_CR14","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100118493","author":"ATK Choy","year":"1992","unstructured":"Choy ATK, Su AP (1992) Bipolar diathermy or ligation for haemostasis in tonsillectomy? A prospective study on post-operative pain. J Laryngol Otol. https:\/\/doi.org\/10.1017\/S0022215100118493","journal-title":"J Laryngol Otol"},{"key":"9186_CR15","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(01)00553-5","author":"RH Temple","year":"2001","unstructured":"Temple RH, Timms MS (2001) Paediatric coblation tonsillectomy. Int J Pediatr Otorhinolaryngol. https:\/\/doi.org\/10.1016\/S0165-5876(01)00553-5","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"9186_CR16","doi-asserted-by":"publisher","DOI":"10.1186\/s40463-019-0368-1","author":"L Liu","year":"2019","unstructured":"Liu L, Rodman C, Worobetz NE, Johnson J, Elmaraghy C, Chiang T (2019) Topical biomaterials to prevent post-tonsillectomy hemorrhage. J Otolaryngol Head Neck Surg. https:\/\/doi.org\/10.1186\/s40463-019-0368-1","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"9186_CR17","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13707","author":"K Keltie","year":"2021","unstructured":"Keltie K, Donne A, Daniel M et al (2021) Paediatric tonsillectomy in England: a cohort study of clinical practice and outcomes using Hospital Episode Statistics data (2008\u20132019). Clin Otolaryngol. https:\/\/doi.org\/10.1111\/coa.13707","journal-title":"Clin Otolaryngol"},{"key":"9186_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2011.11.041","author":"EF Boss","year":"2012","unstructured":"Boss EF, Marsteller JA, Simon AE (2012) Outpatient tonsillectomy in children: demographic and geographic variation in the United States, 2006. J Pediatr. https:\/\/doi.org\/10.1016\/j.jpeds.2011.11.041","journal-title":"J Pediatr"},{"key":"9186_CR19","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(02)00022-8","author":"VV Raut","year":"2002","unstructured":"Raut VV, Bhat N, Sinnathuray AR, Kinsella JB, Stevenson M, Toner JG (2002) Bipolar scissors versus cold dissection for pediatric tonsillectomy\u2014a prospective, randomized pilot study. Int J Pediatr Otorhinolaryngol. https:\/\/doi.org\/10.1016\/S0165-5876(02)00022-8","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"9186_CR20","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10001-1273","author":"S Andreoli","year":"2016","unstructured":"Andreoli S, Josephson GD (2016) Tonsillectomy and adenoidectomy: current techniques and outcomes. Int J Head Neck Surg. https:\/\/doi.org\/10.5005\/jp-journals-10001-1273","journal-title":"Int J Head Neck Surg"},{"key":"9186_CR21","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2000.107454","author":"JL Wei","year":"2000","unstructured":"Wei JL, Beatty CW, Gustafson RO (2000) Evaluation of posttonsillectomy hemorrhage and risk factors. Otolaryngol Head Neck Surg. https:\/\/doi.org\/10.1067\/mhn.2000.107454","journal-title":"Otolaryngol Head Neck Surg"},{"key":"9186_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/0735-6757(95)90161-2","author":"KG Steketee","year":"1995","unstructured":"Steketee KG, Reisdorff EJ (1995) Emergency care for posttonsillectomy and postadenoidectomy hemorrhage. Am J Emerg Med. https:\/\/doi.org\/10.1016\/0735-6757(95)90161-2","journal-title":"Am J Emerg Med"},{"issue":"2","key":"9186_CR23","first-page":"187","volume":"20","author":"A Faramarzi","year":"2010","unstructured":"Faramarzi A, Heydari ST (2010) Prevalence of posttonsillectomy bleeding as daycase surgery with combination method; cold dissection tonsillectomy and bipolar diathermy hemostasis. Iran J Pediatr 20(2):187\u2013192","journal-title":"Iran J Pediatr"},{"key":"9186_CR24","doi-asserted-by":"publisher","DOI":"10.1097\/mlg.0b013e318031f0b0","author":"D Lowe","year":"2007","unstructured":"Lowe D, Van Der Meulen J, Cromwell D et al (2007) Key messages from the national prospective tonsillectomy audit. Laryngoscope. https:\/\/doi.org\/10.1097\/mlg.0b013e318031f0b0","journal-title":"Laryngoscope"},{"key":"9186_CR25","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2016.03.008","author":"RM Mitchell","year":"2016","unstructured":"Mitchell RM, Parikh SR (2016) Hemostasis in tonsillectomy. Otolaryngol Clin North Am. https:\/\/doi.org\/10.1016\/j.otc.2016.03.008","journal-title":"Otolaryngol Clin North Am"},{"key":"9186_CR26","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2007.08.004","author":"A Karatzanis","year":"2008","unstructured":"Karatzanis A, Bourolias C, Prokopakis E, Panagiotaki I, Velegrakis G (2008) Thermal welding technology vs ligasure tonsillectomy: a comparative study. Am J Otolaryngol. https:\/\/doi.org\/10.1016\/j.amjoto.2007.08.004","journal-title":"Am J Otolaryngol"},{"key":"9186_CR27","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71","author":"MJ Page","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM et al (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. The BMJ. https:\/\/doi.org\/10.1136\/bmj.n71","journal-title":"The BMJ"},{"key":"9186_CR28","doi-asserted-by":"publisher","DOI":"10.1046\/j.1445-2197.2003.02748.x","author":"K Slim","year":"2003","unstructured":"Slim K, Nini E, Forestier D, Kwiatkowski F, Panis Y, Chipponi J (2003) Methodological index for non-randomized studies (Minors): development and validation of a new instrument. ANZ J Surg. https:\/\/doi.org\/10.1046\/j.1445-2197.2003.02748.x","journal-title":"ANZ J Surg"},{"key":"9186_CR29","doi-asserted-by":"publisher","unstructured":"Higgins, JPT, Thomas J, Chandler J, et al (2019) Cochrane handbook for systematic reviews of interventions. 2nd edn. John Wiley & Sons. https:\/\/doi.org\/10.1002\/978111536604","DOI":"10.1002\/978111536604"},{"key":"9186_CR30","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pu.09.050188.001011","author":"SJ Kuritz","year":"1988","unstructured":"Kuritz SJ, Landis JR, Koch GG (1988) A general overview of Mantel-Haenszel methods: applications and recent developments. Annu Rev Public Health. https:\/\/doi.org\/10.1146\/annurev.pu.09.050188.001011","journal-title":"Annu Rev Public Health"},{"key":"9186_CR31","doi-asserted-by":"publisher","DOI":"10.1177\/0300060519867822","author":"X Zhou","year":"2019","unstructured":"Zhou X, Xu A, Zhen X et al (2019) Coblation tonsillectomy versus coblation tonsillectomy with ties in adults. J Int Med Res. https:\/\/doi.org\/10.1177\/0300060519867822","journal-title":"J Int Med Res"},{"key":"9186_CR32","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-010-0094-5","author":"K Sharma","year":"2011","unstructured":"Sharma K, Kumar D (2011) Ligation versus bipolar diathermy for hemostasis in tonsillectomy: a comparative study. Indian J Otolaryngol Head Neck Surg. https:\/\/doi.org\/10.1007\/s12070-010-0094-5","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"issue":"3","key":"9186_CR33","first-page":"1434","volume":"14","author":"MA Hezam","year":"2020","unstructured":"Hezam MA, Nasir A, Afridi AU et al (2020) Comparison of bipolar diathermy and suture ligation for haemostasis in tonsillectomy. Pakistan J Med Health Sci 14(3):1434\u20131438","journal-title":"Pakistan J Med Health Sci"},{"key":"9186_CR34","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-023-03778-2","author":"S Bashir","year":"2023","unstructured":"Bashir S, Swami G (2023) Comparative study of bipolar electrocautery versus silk ligation for hemostasis during tonsillectomy. Indian J Otolaryngol Head Neck Surg. https:\/\/doi.org\/10.1007\/s12070-023-03778-2","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"9186_CR35","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100124211","author":"C Rayappa","year":"1993","unstructured":"Rayappa C, Hill J, Deans JAJ (1993) A study of haemostasis following tonsillectomy comparing ligatures with diathermy. J Laryngol Otol. https:\/\/doi.org\/10.1017\/S0022215100124211","journal-title":"J Laryngol Otol"},{"key":"9186_CR36","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2009.09.029","author":"AM Teker","year":"2009","unstructured":"Teker AM, Korkut AY, Gedikli O, Kahya V (2009) Prospective, controlled clinical trial of Ankaferd Blood Stopper in children undergoing tonsillectomy. Int J Pediatr Otorhinolaryngol. https:\/\/doi.org\/10.1016\/j.ijporl.2009.09.029","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"9186_CR37","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2020.1746396","author":"F Lundstr\u00f6m","year":"2020","unstructured":"Lundstr\u00f6m F, Stalfors J, \u00d8stvoll E, Sunnergren O (2020) Practice, complications and outcome in Swedish tonsil surgery 2009\u20132018. An observational longitudinal national cohort study. Acta Otolaryngol. https:\/\/doi.org\/10.1080\/00016489.2020.1746396","journal-title":"Acta Otolaryngol"},{"key":"9186_CR38","doi-asserted-by":"publisher","DOI":"10.21037\/AJO-21-52","author":"R Bigdeli","year":"2022","unstructured":"Bigdeli R, Jabbour J, Budiono G et al (2022) A comparison of tonsillectomy techniques: a 10-year retrospective audit of a large regional hospital in Australia. Aust J Otolaryngol. https:\/\/doi.org\/10.21037\/AJO-21-52","journal-title":"Aust J Otolaryngol"},{"key":"9186_CR39","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198405000-00019","author":"DG Mann","year":"1984","unstructured":"Mann DG, St. George C, Scheiner E, Granoff D, Imber P, Mlynarczyk FA (1984) Tonsillectomy\u2014some like it hot. Laryngoscope. https:\/\/doi.org\/10.1288\/00005537-198405000-00019","journal-title":"Laryngoscope"},{"key":"9186_CR40","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1990.01870020062016","author":"TA Weimert","year":"1990","unstructured":"Weimert TA, Babyak JW, Richter HJ (1990) Electrodissection Tonsillectomy. Arch Otolaryngol Head Neck Surg. https:\/\/doi.org\/10.1001\/archotol.1990.01870020062016","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"9186_CR41","volume-title":"Tonsilitis tonsillitis","author":"SW Basuki","year":"2020","unstructured":"Basuki SW, Nuria I, Ziyaadatulhuda AZ, Utami F, Ardilla N (2020) Tonsilitis tonsillitis. Publikasi Ilmiah UMS (Published online)"},{"key":"9186_CR42","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(96)01364-X","author":"D Myssiorek","year":"1996","unstructured":"Myssiorek D, Alvi A (1996) Post-tonsillectomy hemorrhage: an assessment of risk factors. Int J Pediatr Otorhinolaryngol. https:\/\/doi.org\/10.1016\/0165-5876(96)01364-X","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"9186_CR43","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-011-0268-9","author":"KC Prasad","year":"2011","unstructured":"Prasad KC, Prasad SC (2011) Assessment of operative blood loss and the factors affecting it in tonsillectomy and adenotonsillectomy. Indian J Otolaryngol Head Neck Surg. https:\/\/doi.org\/10.1007\/s12070-011-0268-9","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"9186_CR44","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1976.00780060055004","author":"A Roy","year":"1976","unstructured":"Roy A, De la Rosa C, Vecchio YA (1976) Bleeding following tonsillectomy: a study of electrocoagulation and ligation techniques. Arch Otolaryngol. https:\/\/doi.org\/10.1001\/archotol.1976.00780060055004","journal-title":"Arch Otolaryngol"},{"key":"9186_CR45","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28427","author":"BA Leader","year":"2020","unstructured":"Leader BA, Wiebracht ND, Meinzen-Derr J, Ishman SL (2020) The impact of resident involvement on tonsillectomy outcomes and surgical time. Laryngoscope. https:\/\/doi.org\/10.1002\/lary.28427","journal-title":"Laryngoscope"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-024-09186-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-024-09186-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-024-09186-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T05:24:01Z","timestamp":1746509041000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-024-09186-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,9]]},"references-count":45,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["9186"],"URL":"https:\/\/doi.org\/10.1007\/s00405-024-09186-8","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,9]]},"assertion":[{"value":"9 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors were consulted and there were no conflicts of interest in the writing of this systematic review and meta-analysis.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}