{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:37:22Z","timestamp":1789691842761,"version":"4.0.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T00:00:00Z","timestamp":1741910400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T00:00:00Z","timestamp":1741910400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1007\/s00405-025-09291-2","type":"journal-article","created":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T18:55:43Z","timestamp":1741978543000},"page":"3363-3368","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Hamartomas of the nasal cavity: a case series and review of the literature"],"prefix":"10.1007","volume":"282","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2489-442X","authenticated-orcid":false,"given":"Ahlam H.","family":"Alamri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Alswayyed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma","family":"Alenazy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rayan","family":"Alfallaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saad","family":"Alasmari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman","family":"Aljofan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad S.","family":"Alroqi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,3,14]]},"reference":[{"key":"9291_CR1","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1177\/000348949510400809","volume":"104","author":"BM Wenig","year":"1995","unstructured":"Wenig BM, Heffner DK (1995) Respiratory epithelial adenomatoid hamartomas of the sinonasal tract and nasopharynx: A clinicopathologic study of 31 cases. Ann Otol Rhinol Laryngol 104:639\u2013645. https:\/\/doi.org\/10.1177\/000348949510400809","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"9291_CR2","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1007\/s12105-008-0064-3","volume":"2","author":"VA Fitzhugh","year":"2008","unstructured":"Fitzhugh VA, Mirani N (2008) Respiratory epithelial adenomatoid Hamartoma: A review. Head Neck Pathol 2:203\u2013208. https:\/\/doi.org\/10.1007\/s12105-008-0064-3","journal-title":"Head Neck Pathol"},{"key":"9291_CR3","doi-asserted-by":"publisher","first-page":"1292","DOI":"10.1002\/lio2.914","volume":"7","author":"H Morishita","year":"2022","unstructured":"Morishita H, Kobayashi M, Uchida K, Takeuchi K (2022) Predictors and prognosis of respiratory epithelial adenomatoid Hamartoma in sinonasal cavities. Laryngoscope Investig Otolaryngol 7:1292\u20131298. https:\/\/doi.org\/10.1002\/lio2.914","journal-title":"Laryngoscope Investig Otolaryngol"},{"key":"9291_CR4","doi-asserted-by":"publisher","first-page":"187","DOI":"10.2500\/ajra.2014.28.4085","volume":"28","author":"DT Nguyen","year":"2014","unstructured":"Nguyen DT, Gauchotte G, Arous F, Vignaud J-M, Jankowski R (2014) Respiratory epithelial adenomatoid Hamartoma of the nose: an updated review. Am J Rhinol Amp Allergy 28:187\u2013192. https:\/\/doi.org\/10.2500\/ajra.2014.28.4085","journal-title":"Am J Rhinol Amp Allergy"},{"key":"9291_CR5","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1002\/alr.22298","volume":"9","author":"C Safi","year":"2019","unstructured":"Safi C, Li C, Tabaee A, Ramakrishna R, Riley CA (2019) Outcomes and imaging findings of respiratory epithelial adenomatoid Hamartoma: A systematic review. Int Forum Allergy Rhinol 9:674\u2013680. https:\/\/doi.org\/10.1002\/alr.22298","journal-title":"Int Forum Allergy Rhinol"},{"key":"9291_CR6","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1016\/j.amjoto.2004.02.005","volume":"25","author":"C Delbrouck","year":"2004","unstructured":"Delbrouck C, Fernandez Aguilar S, Choufani G, Hassid S (2004) Respiratory epithelial adenomatoid Hamartoma associated with nasal polyposis. Am J Otolaryngol 25:282\u2013284. https:\/\/doi.org\/10.1016\/j.amjoto.2004.02.005","journal-title":"Am J Otolaryngol"},{"key":"9291_CR7","doi-asserted-by":"publisher","first-page":"2706","DOI":"10.1002\/lary.22399","volume":"121","author":"D Vira","year":"2011","unstructured":"Vira D, Bhuta S, Wang MB (2011) Respiratory epithelial adenomatoid hamartomas. Laryngoscope 121:2706\u20132709. https:\/\/doi.org\/10.1002\/lary.22399","journal-title":"Laryngoscope"},{"key":"9291_CR8","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/j.anl.2009.10.003","volume":"37","author":"Z Cao","year":"2010","unstructured":"Cao Z, Gu Z, Yang J, Jin M (2010) Respiratory epithelial adenomatoid Hamartoma of bilateral olfactory clefts associated with nasal polyposis: three cases report and literature review. Auris Nasus Larynx 37:352\u2013356. https:\/\/doi.org\/10.1016\/j.anl.2009.10.003","journal-title":"Auris Nasus Larynx"},{"key":"9291_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000444957","volume":"79","author":"NR London Jr","year":"2016","unstructured":"London NR Jr, Reh DD (2016) Differential diagnosis of chronic rhinosinusitis with nasal polyps. Adv Otorhinolaryngol 79:1\u201312. https:\/\/doi.org\/10.1159\/000444957","journal-title":"Adv Otorhinolaryngol"},{"key":"9291_CR10","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1136\/jcp.2007.053702","volume":"62","author":"B Perez-Ordo\u00f1ez","year":"2009","unstructured":"Perez-Ordo\u00f1ez B (2009) Hamartomas, papillomas and adenocarcinomas of the sinonasal tract and nasopharynx. J Clin Pathol 62:1085\u20131095. https:\/\/doi.org\/10.1136\/jcp.2007.053702","journal-title":"J Clin Pathol"},{"key":"9291_CR11","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1111\/pin.13271","volume":"72","author":"M Goto","year":"2022","unstructured":"Goto M, Nishimoto K, Jougasaki Y, Matsuzaki T, Nomoto M (2022) Respiratory epithelial adenomatoid hamartomas of the sinonasal tract: A histopathological analysis of 50 patients. Pathol Int 72:541\u2013549. https:\/\/doi.org\/10.1111\/pin.13271","journal-title":"Pathol Int"},{"key":"9291_CR12","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.neurad.2012.04.002","volume":"40","author":"J-J Braun","year":"2013","unstructured":"Braun J-J, Riehm S, Averous G, Billing A, Veillon F (2013) MRI in respiratory epithelial adenomatoid Hamartoma of nasal cavities. J Neuroradiol 40:216\u2013219. https:\/\/doi.org\/10.1016\/j.neurad.2012.04.002","journal-title":"J Neuroradiol"},{"key":"9291_CR13","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1002\/alr.21372","volume":"4","author":"M Bignami","year":"2014","unstructured":"Bignami M, Volpi L, Karligkiotis A et al (2014) Endoscopic endonasal resection of respiratory epithelial adenomatoid hamartomas of the sinonasal tract. Int Forum Allergy Rhinol 4:961\u2013965. https:\/\/doi.org\/10.1002\/alr.21372","journal-title":"Int Forum Allergy Rhinol"},{"key":"9291_CR14","first-page":"264","volume":"44","author":"NB Lima","year":"2006","unstructured":"Lima NB, Jankowski R, Georgel T, Grignon B, Guillemin F, Vignaud JM (2006) Respiratory adenomatoid Hamartoma must be suspected on CT-scan enlargement of the olfactory clefts. Rhinology 44:264\u2013269","journal-title":"Rhinology"},{"key":"9291_CR15","doi-asserted-by":"publisher","first-page":"2461","DOI":"10.1002\/lary.24778","volume":"124","author":"DT Nguyen","year":"2014","unstructured":"Nguyen DT, Nguyen-Thi PL, Gauchotte G, Arous F, Vignaud JM, Jankowski R (2014) Predictors of respiratory epithelial adenomatoid hamartomas of the olfactory clefts in patients with nasal polyposis. Laryngoscope 124:2461\u20132465. https:\/\/doi.org\/10.1002\/lary.24778","journal-title":"Laryngoscope"},{"issue":"4\u20135","key":"9291_CR16","first-page":"191","volume":"131","author":"C Nagouas","year":"2014","unstructured":"Nagouas C, Bastier PL, Lechot A, De Gabory L (2014) Respiratory epithelial adenomatoid hamartomas and olfactory function. Rev Laryngol Otol Rhinol (Bord) 131(4\u20135):191\u2013195","journal-title":"Rev Laryngol Otol Rhinol (Bord)"},{"key":"9291_CR17","doi-asserted-by":"publisher","first-page":"2867","DOI":"10.1007\/s00405-014-3401-z","volume":"272","author":"A Al Hawat","year":"2015","unstructured":"Al Hawat A, Mouchon E, De Bonnecaze G, Vergez S, Serrano E (2015) Our experience with respiratory epithelial adenomatoid hamartomas of the olfactory cleft. Eur Arch Otorhinolaryngol 272:2867\u20132870. https:\/\/doi.org\/10.1007\/s00405-014-3401-z","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"9291_CR18","doi-asserted-by":"publisher","first-page":"322","DOI":"10.2500\/ajra.2013.27.3905","volume":"27","author":"JT Lee","year":"2013","unstructured":"Lee JT, Garg R, Brunworth J, Keschner DB, Thompson LDR (2013) Sinonasal respiratory epithelial adenomatoid Hamartomas: series of 51 cases and literature review. Am J Rhinol Allergy 27:322\u2013328. https:\/\/doi.org\/10.2500\/ajra.2013.27.3905","journal-title":"Am J Rhinol Allergy"},{"key":"9291_CR19","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1002\/alr.21083","volume":"3","author":"KA Hawley","year":"2013","unstructured":"Hawley KA, Pabon S, Hoschar AP, Sindwani R (2013) The presentation and clinical significance of sinonasal respiratory epithelial adenomatoid Hamartoma (REAH). Int Forum Allergy Rhinol 3:248\u2013253. https:\/\/doi.org\/10.1002\/alr.21083","journal-title":"Int Forum Allergy Rhinol"},{"key":"9291_CR20","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1177\/1945892420914212","volume":"34","author":"JS Schertzer","year":"2020","unstructured":"Schertzer JS, Levy JM, Wise SK, Magliocca KR, DelGaudio JM (2020) Is respiratory epithelial adenomatoid Hamartoma related to central compartment atopic disease? Am J Rhinol Allergy 34:610\u2013617. https:\/\/doi.org\/10.1177\/1945892420914212","journal-title":"Am J Rhinol Allergy"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-025-09291-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-025-09291-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-025-09291-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T19:41:14Z","timestamp":1748547674000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-025-09291-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,14]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["9291"],"URL":"https:\/\/doi.org\/10.1007\/s00405-025-09291-2","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,14]]},"assertion":[{"value":"6 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 February 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 March 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval for this case series was obtained from King Saud University, Kingdom of Saudi Arabia (reference No.: 24\/1462\/IRB). The study was carried out according to the World Medical Association\u2019s Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all participants included in this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no conflicts of interest.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}