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All procedures performed in this study were in accordance with the ethical standards of the institutional and\/or national research committee(s) and with the Helsinki Declaration (as revised in 2013). All procedures of this study adhered to the ethical guidelines outlined in the World Medical Association (WMA) Declaration of Helsinki (2013). Ethical approval was granted by the Human Research Ethics Committee of the Second Xiangya Hospital, Central South University (Approval No. Z0847-02). All participants were thoroughly informed of their rights and potential risks associated with the study and provided written informed consent, either personally or through their legal guardians.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors have no conflicts of interest to declare.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}