{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T19:09:46Z","timestamp":1757617786623,"version":"3.44.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum Hamburg-Eppendorf (UKE)"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Purpose<\/jats:title>\n            <jats:p>Flexible endoscopic evaluation of swallowing (FEES) is a gold standard for diagnosing swallowing disorders. This study investigates two image enhancement technologies usable in FEES\u2014hardware filtering (Narrow Band Imaging, NBI<jats:sup>\u00ae<\/jats:sup>) and software filtering (Professional Image Enhancement Technology, PIET<jats:sup>\u00ae<\/jats:sup>)\u2014to assess their effectiveness in improving the visibility of food dyes.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>This Head-to-head study compared NBI<jats:sup>\u00ae<\/jats:sup> and PIET<jats:sup>\u00ae<\/jats:sup> by creating 190 videos showcasing food dyes diluted from 1:10 to 1:100,000, tested in the oral cavities of four volunteers. Four raters evaluated the maximum visible dilution for both systems across all colors. Sixteen snippets representing eight colors (red, yellow, blue, green, purple, orange, black, and white) at a 1:10 dilution were analyzed by 14 raters, including two with no prior FEES experience, all blinded to the filtering method.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>The study used a point system to assess subjective image quality, color intensity, and contrast to the mucosa. Both systems produced similar hues for yellow and red and their secondary colors. PIET was preferred for red and purple, while NBI was favored for yellow, green, and orange. For blue, black, and white (all showing no intensification), PIET was nearly unanimously chosen. Raters agreed 100% on the maximum visible dilution, showing no significant difference between systems; both enhanced visibility tenfold.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Both image enhancement systems improved the visibility of specific food dyes effectively. Each method has distinct advantages. The choice between them depends on personal preference and available systems.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00405-025-09413-w","type":"journal-article","created":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T16:39:54Z","timestamp":1746463194000},"page":"3739-3745","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of filter-based and software-based image enhancement systems for endoscopic swallowing diagnostics: a head-to-head study"],"prefix":"10.1007","volume":"282","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1094-0963","authenticated-orcid":false,"given":"Almut C.","family":"Niessen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0812-4556","authenticated-orcid":false,"given":"Julia","family":"Glinzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4979-4716","authenticated-orcid":false,"given":"Jana","family":"Zang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8374-431X","authenticated-orcid":false,"given":"Christina","family":"Pflug","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,5]]},"reference":[{"key":"9413_CR1","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/j.clnu.2014.04.014","volume":"34","author":"S Carri\u00f3n","year":"2015","unstructured":"Carri\u00f3n S, Cabr\u00e9 M, Monteis R, Roca M, Palomera E, Serra-Prat M, Rofes L, Clav\u00e9 P (2015) Oropharyngeal dysphagia is a prevalent risk factor for malnutrition in a cohort of older patients admitted with an acute disease to a general hospital. Clin Nutr 34:436\u2013442. https:\/\/doi.org\/10.1016\/j.clnu.2014.04.014","journal-title":"Clin Nutr"},{"key":"9413_CR2","doi-asserted-by":"publisher","DOI":"10.1097\/mco.0000000000001086","author":"G Lueg","year":"2024","unstructured":"Lueg G, Pourhassan M, Wirth R (2024) Progress in dysphagia management in older patients. Curr Opin Clin Nutr Metab Care. https:\/\/doi.org\/10.1097\/mco.0000000000001086","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"9413_CR3","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1007\/s00455-016-9775-x","volume":"32","author":"SE Langmore","year":"2017","unstructured":"Langmore SE (2017) History of fiberoptic endoscopic evaluation of swallowing for evaluation and management of pharyngeal dysphagia: changes over the years. Dysphagia 32:27\u201338. https:\/\/doi.org\/10.1007\/s00455-016-9775-x","journal-title":"Dysphagia"},{"key":"9413_CR4","doi-asserted-by":"publisher","first-page":"2002","DOI":"10.1002\/lary.26419","volume":"127","author":"LF Giraldo-Cadavid","year":"2017","unstructured":"Giraldo-Cadavid LF, Leal-Lea\u00f1o LR, Leon-Basantes GA, Bastidas AR, Garcia R, Ovalle S, Abondano-Garavito JE (2017) Accuracy of endoscopic and videofluoroscopic evaluations of swallowing for oropharyngeal dysphagia. Laryngoscope 127:2002\u20132010. https:\/\/doi.org\/10.1002\/lary.26419","journal-title":"Laryngoscope"},{"key":"9413_CR5","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.1002\/lary.26328","volume":"127","author":"S Fleischer","year":"2017","unstructured":"Fleischer S, Pflug C, Hess M (2017) High-Sensitivity fees with Nbi-Illumination. Laryngoscope 127:1140\u20131142. https:\/\/doi.org\/10.1002\/lary.26328","journal-title":"Laryngoscope"},{"key":"9413_CR6","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1007\/s00405-021-07067-y","volume":"279","author":"F Kraus","year":"2022","unstructured":"Kraus F, Hackenberg S, Shehata-Dieler W, Hagen R (2022) High-Sensitivity Fees(\u00ae) with the professional image enhancement technology Piet. Eur Arch Otorhinolaryngol 279:293\u2013298. https:\/\/doi.org\/10.1007\/s00405-021-07067-y","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"9413_CR7","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1007\/s00455-017-9784-4","volume":"32","author":"JC Nienstedt","year":"2017","unstructured":"Nienstedt JC, Muller F, Niessen A, Fleischer S, Koseki JC, Flugel T, Pflug C (2017) Narrow band imaging enhances the detection rate of penetration and aspiration in fees. Dysphagia 32:443\u2013448. https:\/\/doi.org\/10.1007\/s00455-017-9784-4","journal-title":"Dysphagia"},{"key":"9413_CR8","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-021-10309-0","author":"C Stanley","year":"2021","unstructured":"Stanley C, Paddle P, Griffiths S, Safdar A, Phyland D (2021) Detecting aspiration during fees with narrow band imaging in a clinical setting. Dysphagia. https:\/\/doi.org\/10.1007\/s00455-021-10309-0","journal-title":"Dysphagia"},{"key":"9413_CR9","doi-asserted-by":"publisher","first-page":"2035","DOI":"10.1044\/2023_JSLHR-22-00579","volume":"66","author":"A Niessen","year":"2023","unstructured":"Niessen A, Nienstedt JC, Flugel T, Koseki JC, Muller F, Zang J, Pflug C (2023) Narrow band imaging in flexible endoscopic evaluation of Swallowing-How does it work?? J Speech Lang Hear Res 66:2035\u20132046. https:\/\/doi.org\/10.1044\/2023_JSLHR-22-00579","journal-title":"J Speech Lang Hear Res"},{"key":"9413_CR10","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1111\/j.1708-8240.1999.tb00413.x","volume":"11","author":"FN Hattab","year":"1999","unstructured":"Hattab FN, Qudeimat MA, al-Rimawi HS (1999) Dental discoloration: an overview. J Esthet Dent 11:291\u2013310","journal-title":"J Esthet Dent"},{"key":"9413_CR11","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1007\/s13311-012-0133-x","volume":"9","author":"LE Arnold","year":"2012","unstructured":"Arnold LE, Lofthouse N, Hurt E (2012) Artificial food colors and Attention-Deficit\/Hyperactivity symptoms: conclusions to dye for. Neurotherapeutics 9:599\u2013609. https:\/\/doi.org\/10.1007\/s13311-012-0133-x","journal-title":"Neurotherapeutics"},{"key":"9413_CR12","unstructured":"EFSA. Titanium Dioxide: No Longer Considered Safe as Feed Additive (2021) [cited 2024 17.12.24]Available from: https:\/\/www.efsa.europa.eu\/en\/news\/titanium-dioxide-e171-no-longer-considered-safe-when-used-food-additive#faq--efsa-2021-safety-assessment-of-titanium-dioxide-e171"},{"key":"9413_CR13","unstructured":"Sanivarapu RR, Vaqar S, Gibson J, Aspiration Pneumonia (2024) Statpearls. StatPearls Publishing Copyright \u00a9 2024, StatPearls Publishing LLC.: Treasure Island (FL) with ineligible companies. Disclosure: Sarosh Vaqar declares no relevant financial relationships with ineligible companies. Disclosure: Joshua Gibson declares no relevant financial relationships with ineligible companies"},{"key":"9413_CR14","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1055\/s-0040-1710579","volume":"69","author":"G Pines","year":"2021","unstructured":"Pines G, Jacobson F, Zheng Y, Magali P, Lerut T, Bueno R (2021) Long-Term radiologic evaluation of microaspirations among patients after esophagectomy. Thorac Cardiovasc Surg 69:204\u2013210. https:\/\/doi.org\/10.1055\/s-0040-1710579","journal-title":"Thorac Cardiovasc Surg"},{"key":"9413_CR15","doi-asserted-by":"publisher","first-page":"e215","DOI":"10.1016\/s2666-5247(21)00300-1","volume":"3","author":"RL Marsh","year":"2022","unstructured":"Marsh RL, Binks MJ, Smith-Vaughan HC, Janka M, Clark S, Richmond P, Chang AB, Thornton RB (2022) Prevalence and subtyping of biofilms present in Bronchoalveolar lavage from children with protracted bacterial bronchitis or Non-Cystic fibrosis bronchiectasis: A Cross-Sectional study. Lancet Microbe 3:e215\u2013e223. https:\/\/doi.org\/10.1016\/s2666-5247(21)00300-1","journal-title":"Lancet Microbe"},{"key":"9413_CR16","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1007\/s11831-021-09587-6","volume":"29","author":"Y Qi","year":"2022","unstructured":"Qi Y, Yang Z, Sun W, Lou M, Lian J, Zhao W, Deng X, Ma Y (2022) A comprehensive overview of image enhancement techniques. Arch Comput Methods Eng 29:583\u2013607. https:\/\/doi.org\/10.1007\/s11831-021-09587-6","journal-title":"Arch Comput Methods Eng"},{"key":"9413_CR17","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1007\/s00405-009-1121-6","volume":"267","author":"C Piazza","year":"2010","unstructured":"Piazza C, Cocco D, De Benedetto L, Del Bon F, Nicolai P, Peretti G (2010) Narrow band imaging and high definition television in the assessment of laryngeal cancer: A prospective study on 279 patients. Eur Arch Otorhinolaryngol 267:409\u2013414. https:\/\/doi.org\/10.1007\/s00405-009-1121-6","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"9413_CR18","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1097\/MOO.0b013e32835908ac","volume":"20","author":"C Piazza","year":"2012","unstructured":"Piazza C, Del Bon F, Peretti G, Nicolai P (2012) Narrow band imaging in endoscopic evaluation of the larynx. Curr Opin Otolaryngol Head Neck Surg 20:472\u2013476. https:\/\/doi.org\/10.1097\/MOO.0b013e32835908ac","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"9413_CR19","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.1002\/lary.30335","volume":"133","author":"M Fermi","year":"2023","unstructured":"Fermi M, Lo Manto A, Di Massa G, Gallo G, Lupi M, Maiolo V, Montrone G, Lovato L, Presutti L, Mattioli F (2023) Paraglottic space invasion in glottic laryngeal cancer: A Clinical-Pathological study. Laryngoscope 133:1184\u20131190. https:\/\/doi.org\/10.1002\/lary.30335","journal-title":"Laryngoscope"},{"key":"9413_CR20","doi-asserted-by":"publisher","first-page":"10504","DOI":"10.1117\/1.JBO.18.1.010504","volume":"18","author":"VN Le du","year":"2013","unstructured":"Le du VN, Wang Q, Ramella-Roman JC, Pfefer TJ (2013) Monte Carlo modeling of Light-Tissue interactions in narrow band imaging. J Biomed Opt 18:10504. https:\/\/doi.org\/10.1117\/1.JBO.18.1.010504","journal-title":"J Biomed Opt"},{"key":"9413_CR21","doi-asserted-by":"publisher","unstructured":"Rotbeh A, Kazeminia M, Kalantari M, Rajati F (2022) Global prevalence of oral pigmentation and its related factors: a systematic review and meta-analysis. J Stomatol Oral Maxillofac Surg 123(5):e411\u2013e424. https:\/\/doi.org\/10.1016\/j.jormas.2022.01.009. Epub 2022 Jan 20. PMID: 35066171","DOI":"10.1016\/j.jormas.2022.01.009"},{"key":"9413_CR22","doi-asserted-by":"publisher","first-page":"466","DOI":"10.5946\/ce.2015.48.6.466","volume":"48","author":"JY Jang","year":"2015","unstructured":"Jang JY (2015) The past, present, and future of Image-Enhanced endoscopy. Clin Endosc 48:466\u2013475. https:\/\/doi.org\/10.5946\/ce.2015.48.6.466","journal-title":"Clin Endosc"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-025-09413-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-025-09413-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-025-09413-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T13:22:08Z","timestamp":1757164928000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-025-09413-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,5]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["9413"],"URL":"https:\/\/doi.org\/10.1007\/s00405-025-09413-w","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"type":"print","value":"0937-4477"},{"type":"electronic","value":"1434-4726"}],"subject":[],"published":{"date-parts":[[2025,5,5]]},"assertion":[{"value":"19 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 May 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors declare no conflicts of interest. No sources of funding or support except for the loan of the device by Xion.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}