{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T14:00:37Z","timestamp":1773410437766,"version":"3.50.1"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T00:00:00Z","timestamp":1760745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T00:00:00Z","timestamp":1760745600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Featured Clinical Technique of Guangzhou","award":["2023P-TS37"],"award-info":[{"award-number":["2023P-TS37"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1007\/s00405-025-09745-7","type":"journal-article","created":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T20:24:54Z","timestamp":1760819094000},"page":"1289-1298","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The mediating role of remnant cholesterol in the association between obstructive sleep apnea and diabetes: insights from two independent datasets"],"prefix":"10.1007","volume":"283","author":[{"given":"Guokun","family":"Wei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haohong","family":"Lai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juntao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8870-2503","authenticated-orcid":false,"given":"Haidi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,10,18]]},"reference":[{"key":"9745_CR1","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1016\/S0140-6736(13)60734-5","volume":"383","author":"AS Jordan","year":"2014","unstructured":"Jordan AS, McSharry DG, Malhotra A (2014) Adult obstructive sleep apnoea. Lancet (London England) 383:736\u2013747","journal-title":"Lancet (London England)"},{"key":"9745_CR2","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/S2213-2600(19)30198-5","volume":"7","author":"AV Benjafield","year":"2019","unstructured":"Benjafield AV, Ayas NT, Eastwood PR, Heinzer R, Ip MSM, Morrell MJ et al (2019) Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis. Lancet Respiratory Med 7:687\u2013698","journal-title":"Lancet Respiratory Med"},{"key":"9745_CR3","doi-asserted-by":"publisher","first-page":"3154","DOI":"10.2337\/DC13-0042","volume":"36","author":"EJ Boyko","year":"2013","unstructured":"Boyko EJ, Seelig AD, Jacobson IG, Hooper TI, Smith B, Smith TC et al (2013) Sleep characteristics, mental health, and diabetes risk: a prospective study of U.S. Military service members in the millennium cohort study. Diabetes Care 36:3154\u20133161","journal-title":"Diabetes Care"},{"key":"9745_CR4","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1378\/chest.07-0828","volume":"133","author":"E Tasali","year":"2008","unstructured":"Tasali E, Mokhlesi B, Van Cauter E (2008) Obstructive sleep apnea and type 2 diabetes: interacting epidemics. Chest 133:496\u2013506","journal-title":"Chest"},{"key":"9745_CR5","doi-asserted-by":"publisher","first-page":"1070","DOI":"10.1016\/j.chest.2017.05.009","volume":"152","author":"S Reutrakul","year":"2017","unstructured":"Reutrakul S, Mokhlesi B (2017) Obstructive sleep apnea and diabetes: a state of the art review. Chest 152:1070\u20131086","journal-title":"Chest"},{"key":"9745_CR6","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1038\/s41569-023-00846-6","volume":"20","author":"S Redline","year":"2023","unstructured":"Redline S, Azarbarzin A, Peker Y (2023) Obstructive sleep apnoea heterogeneity and cardiovascular disease. Nat Rev Cardiol 20:560\u2013573","journal-title":"Nat Rev Cardiol"},{"key":"9745_CR7","doi-asserted-by":"publisher","first-page":"1448","DOI":"10.4239\/wjd.v15.i7.1448","volume":"15","author":"ED Tenda","year":"2024","unstructured":"Tenda ED, Henrina J, Cha JH, Triono MR, Putri EA, Aristy DJ et al (2024) Obstructive sleep apnea: overlooked comorbidity in patients with diabetes. World J Diabetes 15:1448\u20131460","journal-title":"World J Diabetes"},{"key":"9745_CR8","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1183\/09031936.00166808","volume":"34","author":"P L\u00e9vy","year":"2009","unstructured":"L\u00e9vy P, Bonsignore MR, Eckel J (2009) Sleep, sleep-disordered breathing and metabolic consequences. Eur Respir J 34:243\u2013260","journal-title":"Eur Respir J"},{"key":"9745_CR9","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1183\/09031936.00198810","volume":"38","author":"M Gasa","year":"2011","unstructured":"Gasa M, Salord N, Fortuna AM, Mayos M, Vilarrasa N, Dorca J et al (2011) Obstructive sleep apnoea and metabolic impairment in severe obesity. Eur Respir J 38:1089\u20131097","journal-title":"Eur Respir J"},{"key":"9745_CR10","doi-asserted-by":"publisher","unstructured":"Barros D, Garc\u00eda-R\u00edo F (2019) Obstructive sleep apnea and dyslipidemia: from animal models to clinical evidence. Sleep\u00a042(3):236. https:\/\/doi.org\/10.1093\/sleep\/zsy236","DOI":"10.1093\/sleep\/zsy236"},{"key":"9745_CR11","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1002\/hep.21593","volume":"45","author":"V Savransky","year":"2007","unstructured":"Savransky V, Nanayakkara A, Vivero A, Li J, Bevans S, Smith PL et al (2007) Chronic intermittent hypoxia predisposes to liver injury. Hepatology 45:1007\u20131013","journal-title":"Hepatology"},{"key":"9745_CR12","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1093\/aje\/154.1.50","volume":"154","author":"AB Newman","year":"2001","unstructured":"Newman AB, Nieto FJ, Guidry U, Lind BK, Redline S, Pickering TG et al (2001) Relation of sleep-disordered breathing to cardiovascular disease risk factors: the sleep heart health study. Am J Epidemiol 154:50\u201359","journal-title":"Am J Epidemiol"},{"key":"9745_CR13","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1016\/j.ehj.2004.02.021","volume":"25","author":"SR Coughlin","year":"2004","unstructured":"Coughlin SR, Mawdsley L, Mugarza JA, Calverley PM, Wilding JP (2004) Obstructive sleep apnoea is independently associated with an increased prevalence of metabolic syndrome. Eur Heart J 25:735\u2013741","journal-title":"Eur Heart J"},{"key":"9745_CR14","doi-asserted-by":"publisher","first-page":"1584","DOI":"10.1378\/chest.12-1652","volume":"143","author":"W Trzepizur","year":"2013","unstructured":"Trzepizur W, Le Vaillant M, Meslier N, Pigeanne T, Masson P, Humeau MP et al (2013) Independent association between nocturnal intermittent hypoxemia and metabolic dyslipidemia. Chest 143:1584\u20131589","journal-title":"Chest"},{"key":"9745_CR15","doi-asserted-by":"publisher","first-page":"2117","DOI":"10.2337\/dc19-0100","volume":"42","author":"J Lu","year":"2019","unstructured":"Lu J, Lam SM, Wan Q, Shi L, Huo Y, Chen L et al (2019) High-coverage targeted lipidomics reveals novel serum lipid predictors and lipid pathway dysregulation antecedent to type 2 diabetes onset in normoglycemic Chinese adults. Diabetes Care 42:2117\u20132126","journal-title":"Diabetes Care"},{"key":"9745_CR16","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1172\/JCI33296","volume":"118","author":"LR Brunham","year":"2008","unstructured":"Brunham LR, Kruit JK, Verchere CB, Hayden MR (2008) Cholesterol in islet dysfunction and type 2 diabetes. J Clin Invest 118:403\u2013408","journal-title":"J Clin Invest"},{"key":"9745_CR17","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1007\/s12192-011-0265-7","volume":"16","author":"X Lu","year":"2011","unstructured":"Lu X, Liu J, Hou F, Liu Z, Cao X, Seo H et al (2011) Cholesterol induces pancreatic \u03b2 cell apoptosis through oxidative stress pathway. Cell Stress Chaperones 16:539\u2013548","journal-title":"Cell Stress Chaperones"},{"key":"9745_CR18","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1165\/rcmb.2015-0315OC","volume":"55","author":"M Weiszenstein","year":"2016","unstructured":"Weiszenstein M, Shimoda LA, Koc M, Seda O, Polak J (2016) Inhibition of lipolysis ameliorates diabetic phenotype in a mouse model of obstructive sleep apnea. Am J Respir Cell Mol Biol 55:299\u2013307","journal-title":"Am J Respir Cell Mol Biol"},{"key":"9745_CR19","doi-asserted-by":"publisher","first-page":"305","DOI":"10.2337\/dc22-1550","volume":"46","author":"JH Huh","year":"2023","unstructured":"Huh JH, Roh E, Lee SJ, Ihm SH, Han KD, Kang JG (2023) Remnant cholesterol is an independent predictor of type 2 diabetes: a nationwide population-based cohort study. Diabetes Care 46:305\u2013312","journal-title":"Diabetes Care"},{"key":"9745_CR20","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.1093\/eurheartj\/ehac783","volume":"44","author":"PE St\u00fcrzebecher","year":"2023","unstructured":"St\u00fcrzebecher PE, Katzmann JL, Laufs U (2023) What is \u2018remnant cholesterol\u2019? Eur Heart J 44:1446\u20131448","journal-title":"Eur Heart J"},{"key":"9745_CR21","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1186\/s12933-022-01554-0","volume":"21","author":"X Hu","year":"2022","unstructured":"Hu X, Liu Q, Guo X, Wang W, Yu B, Liang B et al (2022) The role of remnant cholesterol beyond low-density lipoprotein cholesterol in diabetes mellitus. Cardiovasc Diabetol 21:117","journal-title":"Cardiovasc Diabetol"},{"key":"9745_CR22","first-page":"o619","volume":"376","author":"Obstructive sleep apnoea\/hypopnoea","year":"2022","unstructured":"Obstructive sleep apnoea\/hypopnoea (2022) Syndrome and obesity hypoventilation syndrome in over 16s: summary of NICE guidance. BMJ (Clinical Res ed) 376:o619","journal-title":"BMJ (Clinical Res ed)"},{"key":"9745_CR23","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/j.sleh.2022.05.005","volume":"8","author":"V Cavallino","year":"2022","unstructured":"Cavallino V, Rankin E, Popescu A, Gopang M, Hale L, Meliker JR (2022) Antimony and sleep health outcomes: NHANES 2009\u20132016. Sleep Health 8:373\u2013379","journal-title":"Sleep Health"},{"key":"9745_CR24","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1186\/s12944-022-01729-4","volume":"21","author":"YY Xie","year":"2022","unstructured":"Xie YY, Zhao L, Gao LJ, Xu RX, Gao Y, Dou KF et al (2022) Association between remnant cholesterol and verbal learning and memory function in the elderly in the US. Lipids Health Dis 21:120","journal-title":"Lipids Health Dis"},{"key":"9745_CR25","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1186\/s12888-023-04770-4","volume":"23","author":"Y Wang","year":"2023","unstructured":"Wang Y, Shen R (2023) Association of remnant cholesterol with depression among US adults. BMC Psychiatry 23:259","journal-title":"BMC Psychiatry"},{"key":"9745_CR26","first-page":"S5","volume":"47","author":"ADAPP Committee","year":"2023","unstructured":"Committee ADAPP (2023) Summary of revisions: standards of care in Diabetes\u20142024. Diabetes Care 47:S5\u2013S10","journal-title":"Diabetes Care"},{"key":"9745_CR27","doi-asserted-by":"publisher","first-page":"2389","DOI":"10.1001\/jama.2019.19365","volume":"322","author":"YJ Cheng","year":"2019","unstructured":"Cheng YJ, Kanaya AM, Araneta MRG, Saydah SH, Kahn HS, Gregg EW et al (2019) Prevalence of diabetes by race and ethnicity in the united States, 2011\u20132016. JAMA 322:2389\u20132398","journal-title":"JAMA"},{"key":"9745_CR28","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1146\/annurev-publhealth-032315-021402","volume":"37","author":"TJ VanderWeele","year":"2016","unstructured":"VanderWeele TJ (2016) Mediation analysis: a practitioner\u2019s guide. Annu Rev Public Health 37:17\u201332","journal-title":"Annu Rev Public Health"},{"key":"9745_CR29","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1037\/0022-3514.51.6.1173","volume":"51","author":"RM Baron","year":"1986","unstructured":"Baron RM, Kenny DA (1986) The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Personal Soc Psychol 51:1173\u20131182","journal-title":"J Personal Soc Psychol"},{"key":"9745_CR30","doi-asserted-by":"publisher","first-page":"1389","DOI":"10.1001\/jama.2020.3514","volume":"323","author":"DJ Gottlieb","year":"2020","unstructured":"Gottlieb DJ, Punjabi NM (2020) Diagnosis and management of obstructive sleep apnea: a review. JAMA 323:1389\u20131400","journal-title":"JAMA"},{"key":"9745_CR31","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19042459","author":"G Iannella","year":"2022","unstructured":"Iannella G, Magliulo G, Greco A, de Vincentiis M, Ralli M, Maniaci A et al (2022) Obstructive sleep apnea syndrome: from symptoms to treatment. Int J Environ Res Public Health\u00a019(4):2459. https:\/\/doi.org\/10.3390\/ijerph19042459","journal-title":"Int J Environ Res Public Health"},{"key":"9745_CR32","doi-asserted-by":"publisher","DOI":"10.3390\/life14040425","author":"S Lavalle","year":"2024","unstructured":"Lavalle S, Masiello E, Iannella G, Magliulo G, Pace A, Lechien JR et al (2024) Unraveling the complexities of oxidative stress and inflammation biomarkers in obstructive sleep apnea syndrome: a comprehensive review. Life\u00a014(4):425. https:\/\/doi.org\/10.3390\/life14040425","journal-title":"Life"},{"key":"9745_CR33","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd11070204","author":"A Maniaci","year":"2024","unstructured":"Maniaci A, Lavalle S, Parisi FM, Barbanti M, Cocuzza S, Iannella G (2024) Impact of obstructive sleep apnea and sympathetic nervous system on cardiac health: a comprehensive review. J Cardiovasc Dev Dis 11(7):204. https:\/\/doi.org\/10.3390\/jcdd11070204","journal-title":"J Cardiovasc Dev Dis"},{"key":"9745_CR34","doi-asserted-by":"publisher","first-page":"e56","DOI":"10.1161\/CIR.0000000000000988","volume":"144","author":"Y Yeghiazarians","year":"2021","unstructured":"Yeghiazarians Y, Jneid H, Tietjens JR, Redline S, Brown DL, El-Sherif N et al (2021) Obstructive sleep apnea and cardiovascular disease: a scientific statement from the American Heart Association. Circulation 144:e56\u2013e67","journal-title":"Circulation"},{"key":"9745_CR35","doi-asserted-by":"publisher","first-page":"993","DOI":"10.2337\/dc20-2127","volume":"44","author":"B Mokhlesi","year":"2021","unstructured":"Mokhlesi B, Tjaden AH, Temple KA, Edelstein SL, Sam S, Nadeau KJ et al (2021) Obstructive sleep apnea, glucose tolerance, and \u03b2-cell function in adults with prediabetes or untreated type 2 diabetes in the restoring insulin secretion (RISE) study. Diabetes Care 44:993\u20131001","journal-title":"Diabetes Care"},{"key":"9745_CR36","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.plipres.2009.05.001","volume":"48","author":"M Lafontan","year":"2009","unstructured":"Lafontan M, Langin D (2009) Lipolysis and lipid mobilization in human adipose tissue. Prog Lipid Res 48:275\u2013297","journal-title":"Prog Lipid Res"},{"key":"9745_CR37","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1017\/S0029665109990206","volume":"68","author":"IS Wood","year":"2009","unstructured":"Wood IS, de Heredia FP, Wang B, Trayhurn P (2009) Cellular hypoxia and adipose tissue dysfunction in obesity. Proc Nutr Soc 68:370\u2013377","journal-title":"Proc Nutr Soc"},{"key":"9745_CR38","doi-asserted-by":"publisher","first-page":"2253","DOI":"10.2337\/diacare.27.9.2253","volume":"27","author":"G Boden","year":"2004","unstructured":"Boden G, Laakso M (2004) Lipids and glucose in type 2 diabetes: what is the cause and effect? Diabetes Care 27:2253\u20132259","journal-title":"Diabetes Care"},{"key":"9745_CR39","doi-asserted-by":"publisher","first-page":"E12","DOI":"10.1152\/ajpendo.00429.2001","volume":"283","author":"G Boden","year":"2002","unstructured":"Boden G, Cheung P, Stein TP, Kresge K, Mozzoli M (2002) FFA cause hepatic insulin resistance by inhibiting insulin suppression of glycogenolysis. Am J Physiol Endocrinol Metab 283:E12\u2013E19","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"9745_CR40","doi-asserted-by":"publisher","first-page":"4735","DOI":"10.2147\/DMSO.S341285","volume":"14","author":"G Xie","year":"2021","unstructured":"Xie G, Zhong Y, Yang S, Zou Y (2021) Remnant cholesterol is an independent predictor of new-onset diabetes: a single-center cohort study. Diabetes Metab Syndr Obes 14:4735\u2013 4745.","journal-title":"Diabetes Metab Syndr Obes"},{"key":"9745_CR41","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/j.tem.2014.02.003","volume":"25","author":"TJ Biden","year":"2014","unstructured":"Biden TJ, Boslem E, Chu KY, Sue N (2014) Lipotoxic endoplasmic reticulum stress, \u03b2 cell failure, and type 2 diabetes mellitus. Trends Endocrinol Metab 25:389\u2013398","journal-title":"Trends Endocrinol Metab"},{"key":"9745_CR42","doi-asserted-by":"publisher","first-page":"1986","DOI":"10.2337\/db17-1215","volume":"67","author":"S Hauke","year":"2018","unstructured":"Hauke S, Keutler K, Phapale P, Yushchenko DA, Schultz C (2018) Endogenous fatty acids are essential signaling factors of pancreatic \u03b2-cells and insulin secretion. Diabetes 67:1986\u20131998","journal-title":"Diabetes"},{"key":"9745_CR43","doi-asserted-by":"publisher","first-page":"10878","DOI":"10.1073\/pnas.91.23.10878","volume":"91","author":"Y Lee","year":"1994","unstructured":"Lee Y, Hirose H, Ohneda M, Johnson JH, McGarry JD, Unger RH (1994) Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships. Proc Natl Acad Sci U S A 91:10878\u201310882","journal-title":"Proc Natl Acad Sci U S A"},{"key":"9745_CR44","doi-asserted-by":"publisher","first-page":"1911","DOI":"10.1016\/j.cmet.2021.09.001","volume":"33","author":"Y Song","year":"2021","unstructured":"Song Y, Liu J, Zhao K, Gao L, Zhao J (2021) Cholesterol-induced toxicity: an integrated view of the role of cholesterol in multiple diseases. Cell Metab 33:1911\u20131925","journal-title":"Cell Metab"},{"key":"9745_CR45","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1161\/CIRCRESAHA.115.306249","volume":"118","author":"BG Nordestgaard","year":"2016","unstructured":"Nordestgaard BG (2016) Triglyceride-rich lipoproteins and atherosclerotic cardiovascular disease: new insights from epidemiology, genetics, and biology. Circ Res 118:547\u2013563","journal-title":"Circ Res"},{"key":"9745_CR46","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1161\/CIRCRESAHA.108.178533","volume":"103","author":"V Savransky","year":"2008","unstructured":"Savransky V, Jun J, Li J, Nanayakkara A, Fonti S, Moser AB et al (2008) Dyslipidemia and atherosclerosis induced by chronic intermittent hypoxia are attenuated by deficiency of stearoyl coenzyme A desaturase. Circ Res 103:1173\u20131180","journal-title":"Circ Res"},{"key":"9745_CR47","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/S0163-7827(03)00039-0","volume":"43","author":"JM Ntambi","year":"2004","unstructured":"Ntambi JM, Miyazaki M (2004) Regulation of stearoyl-CoA desaturases and role in metabolism. Prog Lipid Res 43:91\u2013104","journal-title":"Prog Lipid Res"},{"key":"9745_CR48","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1152\/physiolgenomics.00293.2005","volume":"25","author":"J Li","year":"2006","unstructured":"Li J, Bosch-Marce M, Nanayakkara A, Savransky V, Fried SK, Semenza GL et al (2006) Altered metabolic responses to intermittent hypoxia in mice with partial deficiency of hypoxia-inducible factor-1alpha. Physiol Genom 25:450\u2013457","journal-title":"Physiol Genom"},{"key":"9745_CR49","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1016\/S0140-6736(81)92140-1","volume":"1","author":"CE Sullivan","year":"1981","unstructured":"Sullivan CE, Issa FG, Berthon-Jones M, Eves L (1981) Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares. Lancet 1:862\u2013865","journal-title":"Lancet"},{"key":"9745_CR50","doi-asserted-by":"publisher","first-page":"1000","DOI":"10.1183\/09031936.00099710","volume":"37","author":"WJ Randerath","year":"2011","unstructured":"Randerath WJ, Verbraecken J, Andreas S, Bettega G, Boudewyns A, Hamans E et al (2011) Non-CPAP therapies in obstructive sleep apnoea. Eur Respir J 37:1000\u20131028","journal-title":"Eur Respir J"},{"key":"9745_CR51","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11092375","author":"G Iannella","year":"2022","unstructured":"Iannella G, Magliulo G, Lo Iacono CAM, Visconti IC, Lechien JR, Perrone T et al (2022) Quality of life and excessive daytime sleepiness in adults with obstructive sleep apnea who are treated with multilevel surgery or adherent to continuous positive airway pressure. J Clin Med 11(9):2375. https:\/\/doi.org\/10.3390\/jcm11092375","journal-title":"J Clin Med"},{"key":"9745_CR52","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1194\/jlr.M083436","volume":"59","author":"LF Drager","year":"2018","unstructured":"Drager LF, Tavoni TM, Silva VM, Santos RD, Pedrosa RP, Bortolotto LA et al (2018) Obstructive sleep apnea and effects of continuous positive airway pressure on triglyceride-rich lipoprotein metabolism. J Lipid Res 59:1027\u20131033","journal-title":"J Lipid Res"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-025-09745-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-025-09745-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-025-09745-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T10:02:57Z","timestamp":1773396177000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-025-09745-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,18]]},"references-count":52,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["9745"],"URL":"https:\/\/doi.org\/10.1007\/s00405-025-09745-7","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,18]]},"assertion":[{"value":"31 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 September 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 October 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the Ethics Committee at SYSMH (approval number: SYSKY-2024-822-01). The NHANES protocol was approved by the Research Ethics Review Board of the National Center for Health Statistics (NCHS), and all participants provided written informed consent.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"All participants agreed to publish.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}