{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:52:46Z","timestamp":1789692766894,"version":"4.0.1"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T00:00:00Z","timestamp":1761264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T00:00:00Z","timestamp":1761264000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1007\/s00405-025-09752-8","type":"journal-article","created":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T16:19:55Z","timestamp":1761322795000},"page":"6297-6306","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Patterns of lymph node recurrence in sinonasal cancers: risk factors and oncological outcomes"],"prefix":"10.1007","volume":"282","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1380-4206","authenticated-orcid":false,"given":"Gianluca","family":"Dalfino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Sileo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessia","family":"Lambertoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto Daniele","family":"Arosio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Monti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Valentini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario Turri","family":"Zanoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Bignami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,10,24]]},"reference":[{"issue":"11","key":"9752_CR1","doi-asserted-by":"publisher","first-page":"2491","DOI":"10.1002\/lary.25465","volume":"125","author":"R Dutta","year":"2015","unstructured":"Dutta R, Dubal PM, Svider PF, Liu JK, Baredes S, Eloy JA (2015) Sinonasal malignancies: a population-based analysis of site-specific incidence and survival. Laryngoscope 125(11):2491\u20132497","journal-title":"Laryngoscope"},{"issue":"2","key":"9752_CR2","first-page":"221","volume":"54","author":"Y Goffart","year":"2000","unstructured":"Goffart Y, Jorissen M, Daele J et al (2000) Minimally invasive endoscopic management of malignant sinonasal tumours. Acta Otorhinolaryngol Belg 54(2):221\u2013232","journal-title":"Acta Otorhinolaryngol Belg"},{"issue":"4","key":"9752_CR3","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1177\/194589240401800409","volume":"18","author":"HJ Roh","year":"2004","unstructured":"Roh HJ, Batra PS, Citardi MJ, Lee J, Bolger WE, Lanza DC (2004) Endoscopic resection of sinonasal malignancies: a preliminary report. Am J Rhinol 18(4):239\u2013246","journal-title":"Am J Rhinol"},{"issue":"11","key":"9752_CR4","doi-asserted-by":"publisher","first-page":"1983","DOI":"10.1097\/01.mlg.0000178330.09881.6b","volume":"115","author":"TZ Shipchandler","year":"2005","unstructured":"Shipchandler TZ, Batra PS, Citardi MJ, Bolger WE, Lanza DC (2005) Outcomes for endoscopic resection of sinonasal squamous cell carcinoma. Laryngoscope 115(11):1983\u20131987","journal-title":"Laryngoscope"},{"issue":"9","key":"9752_CR5","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1080\/00016480600606780","volume":"126","author":"MK Chen","year":"2006","unstructured":"Chen MK (2006) Minimally invasive endoscopic resection of sinonasal malignancies and skull base surgery. Acta Otolaryngol 126(9):981\u2013986","journal-title":"Acta Otolaryngol"},{"issue":"1","key":"9752_CR6","doi-asserted-by":"publisher","first-page":"89","DOI":"10.2500\/ajr.2007.21.2957","volume":"21","author":"V Lund","year":"2007","unstructured":"Lund V, Howard DJ, Wei WI (2007) Endoscopic resection of malignant tumors of the nose and sinuses. Am J Rhinol 21(1):89\u201394","journal-title":"Am J Rhinol"},{"issue":"3","key":"9752_CR7","doi-asserted-by":"publisher","first-page":"308","DOI":"10.2500\/ajr.2008.22.3170","volume":"22","author":"P Nicolai","year":"2008","unstructured":"Nicolai P, Battaglia P, Bignami M (2008) Endoscopic surgery for malignant tumors of the sinonasal tract and adjacent skull base: a 10-year experience. Am J Rhinol 22(3):308\u2013316","journal-title":"Am J Rhinol"},{"issue":"2","key":"9752_CR8","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1002\/lio2.249","volume":"4","author":"DA Carlton","year":"2019","unstructured":"Carlton DA, David Beahm D, Chiu AG (2019) Sinonasal malignancies: endoscopic treatment outcomes. Laryngoscope Investig Otolaryngol 4(2):259\u2013263","journal-title":"Laryngoscope Investig Otolaryngol"},{"issue":"1","key":"9752_CR9","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/j.otc.2015.09.012","volume":"49","author":"P Castelnuovo","year":"2016","unstructured":"Castelnuovo P, Turri-Zanoni M, Battaglia P, Antognoni P, Bossi P, Locatelli D (2016) Sinonasal malignancies of anterior skull base: histology-driven treatment strategies. Otolaryngol Clin North Am 49(1):183\u2013200","journal-title":"Otolaryngol Clin North Am"},{"issue":"10","key":"9752_CR10","doi-asserted-by":"publisher","first-page":"2181","DOI":"10.1007\/s12325-017-0605-9","volume":"34","author":"F L\u00f3pez","year":"2017","unstructured":"L\u00f3pez F, Lund VJ, Su\u00e1rez C (2017) The impact of histologic phenotype in the treatment of sinonasal cancer. Adv Ther 34(10):2181\u20132198","journal-title":"Adv Ther"},{"issue":"3","key":"9752_CR11","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1097\/CCO.0000000000000726","volume":"33","author":"M Ferrari","year":"2021","unstructured":"Ferrari M, Orlandi E, Bossi P (2021) Sinonasal cancers treatments: state of the art. Curr Opin Oncol 33(3):196\u2013205","journal-title":"Curr Opin Oncol"},{"issue":"5","key":"9752_CR12","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1002\/hed.26069","volume":"42","author":"J Zocchi","year":"2020","unstructured":"Zocchi J, Pietrobon G, Campomagnani I (2020) The role of a post therapeutic surveillance program for sinonasal malignancies: analysis of 417 patients. Head Neck 42(5):963\u2013973","journal-title":"Head Neck"},{"issue":"4","key":"9752_CR13","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1002\/lary.28202","volume":"130","author":"E Orlandi","year":"2020","unstructured":"Orlandi E, Cavalieri S, Granata R (2020) Locally advanced epithelial sinonasal tumors: the impact of multimodal approach. Laryngoscope 130(4):857\u2013865","journal-title":"Laryngoscope"},{"issue":"3","key":"9752_CR14","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.critrevonc.2010.08.002","volume":"79","author":"A Franchi","year":"2011","unstructured":"Franchi A, Miligi L, Palomba A, Giovannetti L, Santucci M (2011) Sinonasal carcinomas: recent advances in molecular and phenotypic characterization and their clinical implications. Crit Rev Oncol Hematol 79(3):265\u2013277","journal-title":"Crit Rev Oncol Hematol"},{"issue":"2","key":"9752_CR15","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1097\/MOO.0000000000000445","volume":"26","author":"V Rampinelli","year":"2018","unstructured":"Rampinelli V, Ferrari M, Nicolai P (2018) Intestinal-type adenocarcinoma of the sinonasal tract: an update. Curr Opin Otolaryngol Head Neck Surg 26(2):115\u2013121","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"issue":"5","key":"9752_CR16","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1177\/1945892419856976","volume":"33","author":"VM Lu","year":"2019","unstructured":"Lu VM, Ravindran K, Phan K (2019) Surgical outcomes of endoscopic versus open resection for primary sinonasal malignancy: a meta-analysis. Am J Rhinol Allergy 33(5):608\u2013616","journal-title":"Am J Rhinol Allergy"},{"issue":"5","key":"9752_CR17","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1002\/lary.27301","volume":"129","author":"EC Kuan","year":"2019","unstructured":"Kuan EC, Nasser HB, Carey RM et al (2019) A population-based analysis of nodal metastases in Esthesioneuroblastomas of the Sinonasal tract. Laryngoscope 129(5):1025\u20131029","journal-title":"Laryngoscope"},{"issue":"1","key":"9752_CR18","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1002\/hed.26457","volume":"43","author":"CM Chweya","year":"2021","unstructured":"Chweya CM, Low CM, Van Gompel JJ, Van Abel KM, Stokken JK, Choby G (2021) Population-based analysis on the effect of nodal and distant metastases in sinonasal adenocarcinoma. Head Neck 43(1):128\u2013136","journal-title":"Head Neck"},{"issue":"4","key":"9752_CR19","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1016\/j.oraloncology.2012.10.002","volume":"49","author":"H Mirghani","year":"2013","unstructured":"Mirghani H, Hartl D, Mortuaire G (2013) Nodal recurrence of sinonasal cancer: does the risk of cervical relapse justify a prophylactic neck treatment? Oral Oncol 49(4):374\u2013380","journal-title":"Oral Oncol"},{"issue":"3","key":"9752_CR20","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1055\/s-0037-1607288","volume":"79","author":"BW Peck","year":"2018","unstructured":"Peck BW, Van Abel KM, Moore EJ, Price DL (2018) Rates and locations of regional metastases in sinonasal malignancies: the Mayo Clinic experience. J Neurol Surg B Skull Base 79(3):282\u2013288","journal-title":"J Neurol Surg B Skull Base"},{"issue":"11","key":"9752_CR21","doi-asserted-by":"publisher","first-page":"2451","DOI":"10.1002\/lary.27866","volume":"129","author":"SA Kim","year":"2019","unstructured":"Kim SA, Chung YS, Lee BJ (2019) Recurrence patterns of sinonasal cancers after a 5-year disease-free period. Laryngoscope 129(11):2451\u20132457","journal-title":"Laryngoscope"},{"key":"9752_CR22","volume-title":"AJCC Cancer Staging Manual","author":"MB Amin","year":"2017","unstructured":"Amin MB, American Joint Committee on Cancer, American Cancer Society (2017) AJCC Cancer Staging Manual, 8th edn. editor-in-chief, Mahul B. Amin, MD, FCAP; editors, Stephen B. Edge, MD, FACS [and 16 others] ; Donna M. Gress, RHIT, CTR-Technical editor; Laura R. Meyer, CAPM-Managing editor. American Joint Committee on Cancer, Springer","edition":"8"},{"issue":"4","key":"9752_CR23","doi-asserted-by":"publisher","first-page":"e255","DOI":"10.1016\/j.ijrobp.2011.03.036","volume":"81","author":"C Demiroz","year":"2011","unstructured":"Demiroz C, Gutfeld O, Aboziada M, Brown D, Marentette LJ, Eisbruch A (2011) Esthesioneuroblastoma: is there a need for elective neck treatment? Int J Radiat Oncol Biol Phys 81(4):e255\u2013e261","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"10","key":"9752_CR24","doi-asserted-by":"publisher","first-page":"1372","DOI":"10.1002\/hed.21940","volume":"34","author":"EH Mitchell","year":"2012","unstructured":"Mitchell EH, Diaz A, Yilmaz T et al (2012) Multimodality treatment for sinonasal neuroendocrine carcinoma. Head Neck 34(10):1372\u20131376","journal-title":"Head Neck"},{"key":"9752_CR25","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.ejca.2022.05.010","volume":"171","author":"M Ferrari","year":"2022","unstructured":"Ferrari M, Mattavelli D, Tomasoni M et al (2022) The MUSES\u2217: a prognostic study on 1360 patients with sinonasal cancer undergoing endoscopic surgery-based treatment: \u2217MUlti-institutional collaborative study on Endoscopically treated Sinonasal cancers. Eur J Cancer 171:161\u2013182","journal-title":"Eur J Cancer"},{"key":"9752_CR26","doi-asserted-by":"publisher","first-page":"106123","DOI":"10.1016\/j.oraloncology.2022.106123","volume":"134","author":"AD Arosio","year":"2022","unstructured":"Arosio AD, Bernasconi DP, Valsecchi MG et al (2022) Patterns of recurrences in sinonasal cancers undergoing an endoscopic surgery-based treatment: results of the MUSES* on 940 patients: *MUlti-institutional collaborative study on Endoscopically treated Sinonasal cancers. Oral Oncol 134:106123","journal-title":"Oral Oncol"},{"issue":"5","key":"9752_CR27","first-page":"433","volume":"59","author":"A De Virgilio","year":"2021","unstructured":"De Virgilio A, Costantino A, Sebastiani D, Russo E, Franzese C, Mercante G et al (2021) Elective neck irradiation in the management of esthesioneuroblastoma: a systematic review and meta-analysis. Rhinology 59(5):433\u2013440","journal-title":"Rhinology"},{"issue":"11","key":"9752_CR28","doi-asserted-by":"publisher","first-page":"1935","DOI":"10.1097\/00005537-200311000-00015","volume":"113","author":"A Ferlito","year":"2003","unstructured":"Ferlito A, Rinaldo A, Rhys-Evans PH (2003) Contemporary clinical commentary: esthesioneuroblastoma: an update on management of the neck. Laryngoscope 113(11):1935\u20131938","journal-title":"Laryngoscope"},{"issue":"5","key":"9752_CR29","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1002\/hed.26077","volume":"42","author":"M Faisal","year":"2020","unstructured":"Faisal M, Seemann R, Lill C, Hamzavi S, Wutzl A, Erovic BM et al (2020) Elective neck treatment in sinonasal undifferentiated carcinoma: systematic review and meta-analysis. Head Neck 42(5):1057\u20131066","journal-title":"Head Neck"},{"issue":"11","key":"9752_CR30","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13112835","volume":"13","author":"M Ferrari","year":"2021","unstructured":"Ferrari M, Taboni S, Carobbio ALC, Emanuelli E, Maroldi R, Bossi P et al (2021) Sinonasal squamous cell carcinoma, a narrative reappraisal of the current evidence. Cancers (Basel) 13(11):2835","journal-title":"Cancers (Basel)"},{"issue":"5","key":"9752_CR31","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1007\/s00405-013-2591-0","volume":"271","author":"RP Takes","year":"2014","unstructured":"Takes RP, Ferlito A, Silver CE, Rinaldo A, Medina JE, Robbins KT et al (2014) The controversy in the management of the N0 neck for squamous cell carcinoma of the maxillary sinus. European Archives of Oto-Rhino-Laryngology 271(5):899\u2013904","journal-title":"European Archives of Oto-Rhino-Laryngology"},{"issue":"3","key":"9752_CR32","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/S0360-3016(99)00453-8","volume":"46","author":"QT Le","year":"2000","unstructured":"Le QT, Fu KK, Kaplan MJ, Terris DJ, Fee WE, Goffinet DR (2000) Lymph node metastasis in maxillary sinus carcinoma. Int J Radiat Oncol Biol Phys 46(3):541\u2013549","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"4","key":"9752_CR33","doi-asserted-by":"publisher","first-page":"304","DOI":"10.3857\/roj.2018.00416","volume":"36","author":"WH Lee","year":"2018","unstructured":"Lee WH, Choi SH, Kim SH, Choi EC, Lee CG, Keum KC (2018) Elective neck treatment in clinically node-negative paranasal sinus carcinomas: impact on treatment outcome. Radiat Oncol J 36(4):304\u2013316","journal-title":"Radiat Oncol J"},{"issue":"12","key":"9752_CR34","doi-asserted-by":"publisher","first-page":"3655","DOI":"10.1002\/hed.26418","volume":"42","author":"KL Crawford","year":"2020","unstructured":"Crawford KL, Jafari A, Qualliotine JR, Stuart E, DeConde AS, Califano JA et al (2020) Elective neck dissection for T3\/T4 cN0 sinonasal squamous cell carcinoma. Head Neck 42(12):3655\u20133662","journal-title":"Head Neck"},{"issue":"8","key":"9752_CR35","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13081842","volume":"13","author":"C Galloni","year":"2021","unstructured":"Galloni C, Locatello LG, Bruno C, Cannavicci A, Maggiore G, Gallo O (2021) The role of elective neck treatment in the management of Sinonasal carcinomas: a systematic review of the literature and a meta-analysis. Cancers (Basel) 13(8):1842","journal-title":"Cancers (Basel)"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-025-09752-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-025-09752-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-025-09752-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T18:57:50Z","timestamp":1764961070000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-025-09752-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,24]]},"references-count":35,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["9752"],"URL":"https:\/\/doi.org\/10.1007\/s00405-025-09752-8","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,24]]},"assertion":[{"value":"8 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 September 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 October 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interest"}},{"value":"This study was performed in compliance with the Helsinki Declaration and approved by the Institutional Review Board (Insubria Board of Ethics, approval number 0033025\/2015). Written informed consent was obtained from all patients prior to any diagnostic or therapeutic procedure.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}