{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T01:58:10Z","timestamp":1781056690292,"version":"3.54.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T00:00:00Z","timestamp":1773532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T00:00:00Z","timestamp":1773532800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1007\/s00405-026-10164-5","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T09:49:58Z","timestamp":1773654598000},"page":"3743-3751","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Corticosteroids sparing effect of artemisia annua sublingual immunotherapy: A prospective study in pediatric seasonal allergic rhinoconjunctivitis (INCs sparing and efficacy of Artemisia annua SLIT in pediatric SARC)"],"prefix":"10.1007","volume":"283","author":[{"given":"Xiaoxi","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guohua","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samin","family":"Gholami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengfei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huajing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lifeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9984-9121","authenticated-orcid":false,"given":"Fang","family":"Quan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,15]]},"reference":[{"key":"10164_CR1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2023.1244146","volume":"11","author":"M Blaiss","year":"2023","unstructured":"Blaiss M, DuBuske L, Nolte H et al (2023) A practical guide to prescribing sublingual immunotherapy tablets in North America for pediatric allergic rhinoconjunctivitis: an injection-free allergy immunotherapy option. Front Pediatr 11:1244146. https:\/\/doi.org\/10.3389\/fped.2023.1244146","journal-title":"Front Pediatr"},{"issue":"2","key":"10164_CR2","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1007\/s00405-024-09088-9","volume":"282","author":"J Li","year":"2025","unstructured":"Li J, Liu W, Xu YJ et al (2025) Coseasonal initiation of Artemisia annua sublingual immunotherapy in children and adult patients with allergic rhinoconjunctivitis. Eur Arch Otorhinolaryngol 282(2):843\u2013850. https:\/\/doi.org\/10.1007\/s00405-024-09088-9","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"3","key":"10164_CR3","doi-asserted-by":"publisher","first-page":"173","DOI":"10.2500\/aap.2024.45.240009","volume":"45","author":"K Wang","year":"2024","unstructured":"Wang K, Zhang Y, Wan L et al (2024) Comparison of clinical traits for seasonal and perennial allergic rhinitis during allergen exposure. Allergy Asthma Proc 45(3):173\u2013179. https:\/\/doi.org\/10.2500\/aap.2024.45.240009","journal-title":"Allergy Asthma Proc"},{"issue":"1","key":"10164_CR4","doi-asserted-by":"publisher","DOI":"10.1186\/s12905-021-01345-x","volume":"21","author":"M Fereidouni","year":"2021","unstructured":"Fereidouni M, Rezapour H, Saharkhiz M et al (2021) A study of the association of cognitive abilities and emotional function with allergic disorders in young women. BMC Womens Health 21(1):205. https:\/\/doi.org\/10.1186\/s12905-021-01345-x","journal-title":"BMC Womens Health"},{"key":"10164_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcsop.2023.100340","volume":"12","author":"R House","year":"2023","unstructured":"House R, Kritikos V, Cvetkovski B et al (2023) The impact of implementing an allergic rhinitis clinical management pathway (AR-CMaP) in the community pharmacy. Explor Res Clin Soc Pharm 12:100340. https:\/\/doi.org\/10.1016\/j.rcsop.2023.100340","journal-title":"Explor Res Clin Soc Pharm"},{"key":"10164_CR6","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.jpeds.2016.03.063","volume":"174","author":"MA Strom","year":"2016","unstructured":"Strom MA, Silverberg JI (2016) Associations of physical activity and sedentary behavior with atopic disease in United States children. J Pediatr 174:247-253.e3. https:\/\/doi.org\/10.1016\/j.jpeds.2016.03.063","journal-title":"J Pediatr"},{"key":"10164_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jhealeco.2016.05.005","volume":"49","author":"SS Bensnes","year":"2016","unstructured":"Bensnes SS (2016) You sneeze, you lose: the impact of pollen exposure on cognitive performance during high-stakes high school exams. J Health Econ 49:1\u201313. https:\/\/doi.org\/10.1016\/j.jhealeco.2016.05.005","journal-title":"J Health Econ"},{"issue":"4","key":"10164_CR8","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00074-2022","volume":"8","author":"L Hedman","year":"2022","unstructured":"Hedman L, Almqvist L, Bjerg A et al (2022) Early-life risk factors for development of asthma from 8 to 28\u2005years of age: a prospective cohort study. ERJ Open Res 8(4):00074-2022. https:\/\/doi.org\/10.1183\/23120541.00074-2022","journal-title":"ERJ Open Res"},{"issue":"4","key":"10164_CR9","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1016\/j.jaip.2018.11.044","volume":"7","author":"M Gotoh","year":"2019","unstructured":"Gotoh M, Yonekura S, Imai T et al (2019) Long-term efficacy and dose-finding trial of Japanese cedar pollen sublingual immunotherapy tablet. J Allergy Clin Immunol Pract 7(4):1287-1297.e8. https:\/\/doi.org\/10.1016\/j.jaip.2018.11.044","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"6","key":"10164_CR10","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.1111\/all.13388","volume":"73","author":"XY Wang","year":"2018","unstructured":"Wang XY, Ma TT, Wang XY et al (2018) Prevalence of pollen-induced allergic rhinitis with high pollen exposure in grasslands of northern China. Allergy 73(6):1232\u20131243. https:\/\/doi.org\/10.1111\/all.13388","journal-title":"Allergy"},{"key":"10164_CR11","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.154882","volume":"831","author":"B Adams-Groom","year":"2022","unstructured":"Adams-Groom B, Selby K, Derrett S et al (2022) Pollen season trends as markers of climate change impact: Betula, Quercus and Poaceae. Sci Total Environ 831:154882. https:\/\/doi.org\/10.1016\/j.scitotenv.2022.154882","journal-title":"Sci Total Environ"},{"issue":"1","key":"10164_CR12","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-025-01206-9","volume":"25","author":"CK Chou","year":"2025","unstructured":"Chou CK, Winker R, Rebuli ME et al (2025) Respiratory health impacts from natural disasters and other extreme weather events: the role of environmental stressors on asthma and allergies. Curr Allergy Asthma Rep 25(1):25. https:\/\/doi.org\/10.1007\/s11882-025-01206-9","journal-title":"Curr Allergy Asthma Rep"},{"issue":"4 Pt 1","key":"10164_CR13","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1016\/s0091-6749(98)70271-4","volume":"102","author":"J Bousquet","year":"1998","unstructured":"Bousquet J, Lockey R, Malling HJ (1998) Allergen immunotherapy: therapeutic vaccines for allergic diseases. A WHO position paper. J Allergy Clin Immunol 102(4 Pt 1):558\u2013562. https:\/\/doi.org\/10.1016\/s0091-6749(98)70271-4","journal-title":"J Allergy Clin Immunol"},{"issue":"4","key":"10164_CR14","doi-asserted-by":"publisher","first-page":"415","DOI":"10.5935\/0004-2749.20220053","volume":"85","author":"CS Ronconi","year":"2021","unstructured":"Ronconi CS, Issaho DC, Ejzenbaum F et al (2021) Brazilian guidelines for the monitoring and treatment of pediatric allergic conjunctivitis. Arq Bras Oftalmol 85(4):415\u2013425. https:\/\/doi.org\/10.5935\/0004-2749.20220053","journal-title":"Arq Bras Oftalmol"},{"issue":"3","key":"10164_CR15","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/j.pedhc.2024.07.012","volume":"39","author":"K Rance","year":"2025","unstructured":"Rance K, Banasiak N, Filippelli A et al (2025) Diagnosis and management of pediatric allergic rhinoconjunctivitis in the US. J Pediatr Health Care 39(3):489\u2013502. https:\/\/doi.org\/10.1016\/j.pedhc.2024.07.012","journal-title":"J Pediatr Health Care"},{"issue":"1","key":"10164_CR16","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/1939-4551-7-6","volume":"7","author":"GW Canonica","year":"2014","unstructured":"Canonica GW, Cox L, Pawankar R et al (2014) Sublingual immunotherapy: World Allergy Organization position paper 2013 update. World Allergy Organ J 7(1):6. https:\/\/doi.org\/10.1186\/1939-4551-7-6","journal-title":"World Allergy Organ J"},{"key":"10164_CR17","unstructured":"Subspecialty Group of Rhinology, Editorial Board of ChineseJournal of Otorhinolaryngology Head and Neck Surgery, SubspecialtyGroup of Rhinology, Society of Otorhinolaryngology Headand Neck Surgery, Chinese Medical Association (2022) ZhonghuaEr Bi Yan Hou Tou Jing Wai Ke Za Zhi 57(2):106\u2013129. 10. 3760\/ cma.j. cn115 330- 20211 228- 00828."},{"issue":"8","key":"10164_CR18","doi-asserted-by":"publisher","first-page":"2026","DOI":"10.1111\/all.14218","volume":"75","author":"H Lou","year":"2020","unstructured":"Lou H, Huang Y, Ouyang Y et al (2020) Artemisia annua-sublingual immunotherapy for seasonal allergic rhinitis: a randomized controlled trial. Allergy 75(8):2026\u20132036. https:\/\/doi.org\/10.1111\/all.14218","journal-title":"Allergy"},{"issue":"9","key":"10164_CR19","doi-asserted-by":"publisher","DOI":"10.1016\/j.waojou.2020","volume":"13","author":"H Lou","year":"2020","unstructured":"Lou H, Wang X, Wei Q et al (2020) Artemisia Annua sublingual immunotherapy for seasonal allergic rhinitis: a multicenter, randomized trial. World Allergy Organ J 13(9):100458. https:\/\/doi.org\/10.1016\/j.waojou.2020","journal-title":"World Allergy Organ J"},{"issue":"5","key":"10164_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2023.103942","volume":"44","author":"Y Feng","year":"2023","unstructured":"Feng Y, Cao Y, Liu Y et al (2023) Clinical efficacyand safety of coseasonal initiation of Artemisia annua sublingual immunotherapy on patients with Artemisia induced rhinoconjunctivitis. Am J Otolaryngol 44(5):10 3942. https:\/\/doi.org\/10.1016\/j.amjoto.2023.103942","journal-title":"Am J Otolaryngol"},{"issue":"Suppl 86","key":"10164_CR21","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1111\/j.1398-9995.2007.01620.x","volume":"63","author":"J Bousquet","year":"2008","unstructured":"Bousquet J, Khaltaev N, Cruz AA et al (2008) Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the world health organization, GA (2) LEN and AllerGen). Allergy 63(Suppl 86):8\u2013160. https:\/\/doi.org\/10.1111\/j.1398-9995.2007.01620.x","journal-title":"Allergy"},{"issue":"1","key":"10164_CR22","doi-asserted-by":"publisher","first-page":"52","DOI":"10.18502\/ijaai.v23i1.14953","volume":"23","author":"Y Li","year":"2024","unstructured":"Li Y, Xiao H, Zeng Y et al (2024) Baseline severity and disease duration can predict the response to allergen-specific immunotherapy in allergic rhinitis. Iran J Allergy Asthma Immunol 23(1):52\u201358. https:\/\/doi.org\/10.18502\/ijaai.v23i1.14953","journal-title":"Iran J Allergy Asthma Immunol"},{"issue":"5","key":"10164_CR23","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1097\/ACI.0000000000000475","volume":"18","author":"A Prince","year":"2018","unstructured":"Prince A, Norris MR, Bielory L et al (2018) Seasonal ocular allergy and pollen counts. Curr Opin Allergy Clin Immunol 18(5):387\u2013392. https:\/\/doi.org\/10.1097\/ACI.0000000000000475","journal-title":"Curr Opin Allergy Clin Immunol"},{"issue":"5","key":"10164_CR24","doi-asserted-by":"publisher","first-page":"1376","DOI":"10.1111\/all.16073","volume":"79","author":"L Tang","year":"2024","unstructured":"Tang L, Wang P, Yang X et al (2024) Artemisia annua sublingual immunotherapy in children with seasonal allergic rhinitis. Allergy 79(5):1376\u20131379. https:\/\/doi.org\/10.1111\/all.16073","journal-title":"Allergy"},{"issue":"2","key":"10164_CR25","doi-asserted-by":"publisher","first-page":"82","DOI":"10.5415\/apallergy.0000000000000197","volume":"15","author":"Y Feng","year":"2025","unstructured":"Feng Y, Zhao Y, Hu HX et al (2025) Artemisia annua sublingual immunotherapy in pediatric patients with seasonal allergic rhinoconjunctivitis: comparison to adult patients. Asia Pac Allergy 15(2):82\u201388. https:\/\/doi.org\/10.5415\/apallergy.0000000000000197","journal-title":"Asia Pac Allergy"},{"issue":"3 Suppl 1","key":"10164_CR26","doi-asserted-by":"publisher","first-page":"S390","DOI":"10.1016\/j.jaci.2004.12.014","volume":"115","author":"EF Juniper","year":"2005","unstructured":"Juniper EF, St\u00e5hl E, Doty RL et al (2005) Clinical outcomes and adverse effect monitoring in allergic rhinitis. J Allergy Clin Immunol 115(3 Suppl 1):S390-413. https:\/\/doi.org\/10.1016\/j.jaci.2004.12.014","journal-title":"J Allergy Clin Immunol"},{"issue":"2","key":"10164_CR27","doi-asserted-by":"publisher","DOI":"10.1542\/peds.105.2.e23","volume":"105","author":"DP Skoner","year":"2000","unstructured":"Skoner DP, Rachelefsky GS, Meltzer EO et al (2000) Detection of growth suppression in children during treatment with intranasal beclomethasone dipropionate. Pediatrics 105(2):E23. https:\/\/doi.org\/10.1542\/peds.105.2.e23","journal-title":"Pediatrics"},{"issue":"1","key":"10164_CR28","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.aller.2018.02.008","volume":"47","author":"L Cheng","year":"2019","unstructured":"Cheng L, Zhou WC (2019) Sublingual immunotherapy of house dust mite respiratory allergy in China. Allergol Immunopathol (Madr) 47(1):85\u201389. https:\/\/doi.org\/10.1016\/j.aller.2018.02.008","journal-title":"Allergol Immunopathol (Madr)"},{"issue":"2","key":"10164_CR29","doi-asserted-by":"publisher","first-page":"185","DOI":"10.21037\/tp-23-1","volume":"12","author":"L Li","year":"2023","unstructured":"Li L, Cao B, Sun X et al (2023) Internet follow-up can improve the compliance of sublingual immunotherapy in children with allergic rhinitis: a retrospective cohort study. Transl Pediatr 12(2):185\u2013193. https:\/\/doi.org\/10.21037\/tp-23-1","journal-title":"Transl Pediatr"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-026-10164-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-026-10164-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-026-10164-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T01:04:03Z","timestamp":1781053443000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-026-10164-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,15]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10164"],"URL":"https:\/\/doi.org\/10.1007\/s00405-026-10164-5","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,15]]},"assertion":[{"value":"12 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}