{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T21:01:39Z","timestamp":1784667699328,"version":"3.55.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100003500","name":"Universit\u00e0 degli Studi di Padova","doi-asserted-by":"publisher","award":["2024DNS1DOR-00991"],"award-info":[{"award-number":["2024DNS1DOR-00991"]}],"id":[{"id":"10.13039\/501100003500","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1007\/s00405-026-10278-w","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T08:22:43Z","timestamp":1780388563000},"page":"4505-4513","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic potential of a panel of acoustic\/aerodynamic voice markers in patients with dysphonia: a cluster analysis"],"prefix":"10.1007","volume":"283","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2306-4088","authenticated-orcid":false,"given":"Leonardo","family":"Franz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Letizia","family":"Nicoletti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgia","family":"Martinelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Capovilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Di Salvio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Tuon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariella","family":"Biscaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Montino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuela","family":"Lucchini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cosimo","family":"de Filippis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"Zanoletti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gino","family":"Marioni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,1]]},"reference":[{"key":"10278_CR1","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1177\/0194599817743496","volume":"158","author":"RJ Stachler","year":"2018","unstructured":"Stachler RJ, Francis DO, Schwartz SR, Damask CC, Digoy GP, Krouse HJ, McCoy SJ, Ouellette DR, Patel RR, Reavis CCW, Smith LJ, Smith M, Strode SW, Woo P, Nnacheta LC (2018) Clinical practice guideline: hoarseness (dysphonia) (update). Otolaryngol Head Neck Surg 158:S1\u2013S42. https:\/\/doi.org\/10.11.77\/0194599817751030","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10278_CR2","doi-asserted-by":"publisher","first-page":"5611","DOI":"10.1007\/s12070-021-02952-8","volume":"74","author":"A Chavan","year":"2022","unstructured":"Chavan A, Maran R, Chavan G (2022) Dysphonia: epidemiology, diagnosis and risk factors at tertiary health care center. Indian J Otolaryngol Head Neck Surg 74:5611\u20135615. https:\/\/doi.org\/10.1007\/s12070-021-02952-8","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"10278_CR3","unstructured":"Neighbors C, Hashmi MF, Song SA (2025) Dysphonia. In: StatPearls [Internet]. StatPearls Publishing, Treasure Island (FL). https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK565881\/ Accessed 6 Jan 2026"},{"key":"10278_CR4","doi-asserted-by":"publisher","first-page":"1988","DOI":"10.1097\/01.mlg.0000179174.32345.41","volume":"115","author":"N Roy","year":"2005","unstructured":"Roy N, Merrill RM, Gray SD, Smith EM (2005) Voice disorders in the general population: prevalence, risk factors, and occupational impact. Laryngoscope 115:1988\u20131995. https:\/\/doi.org\/10.1097\/01.mlg.0000179174.32345.41","journal-title":"Laryngoscope"},{"key":"10278_CR5","unstructured":"Schindler A, Ginocchio D, Schindler O (2017) Linee guida per la pratica clinica della disfonia. [Guidelines for Clinical practice of Dysphonia]. Milano: SIFEL \u2013 Societ\u00e0 Italiana di Foniatria e Logopedia. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK563182\/. Accessed 6 Jan 2026"},{"key":"10278_CR6","unstructured":"Naqvi Y, Gupta V (2025) Functional voice disorders in: statPearls [Internet]. Treasure Island (FL): StatPearls Publishing. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK563182\/. Accessed 6 Jan 2026"},{"issue":"3","key":"10278_CR7","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1002\/mdc3.12609","volume":"5","author":"DS Chung","year":"2018","unstructured":"Chung DS, Wettroth C, Hallett M, Maurer CW (2018) Functional speech and voice disorders: case series and literature review. Mov Disord Clin Pract 5(3):312\u2013316. https:\/\/doi.org\/10.1002\/mdc3.12609","journal-title":"Mov Disord Clin Pract"},{"key":"10278_CR8","doi-asserted-by":"publisher","unstructured":"Hunter EJ, Cantor-Cutiva LC, Walden PR (2025) From screening to precision: Searching for voice disorder-specific acoustic and auditory-perceptual metrics. J Voice In press. https:\/\/doi.org\/10.1016\/j.jvoice.2025.09.007","DOI":"10.1016\/j.jvoice.2025.09.007"},{"key":"10278_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2024.104533","volume":"46","author":"A Roitman","year":"2025","unstructured":"Roitman A, Edelstain Y, Katzir C, Ofir H, Peleg N, Doweck I, Yanir Y (2025) Harnessing machine learning in diagnosing complex hoarseness cases. Am J Otolaryngol 46:104533. https:\/\/doi.org\/10.1016\/j.amjoto.2024.104533","journal-title":"Am J Otolaryngol"},{"issue":"1","key":"10278_CR10","doi-asserted-by":"publisher","DOI":"10.1186\/s12911-025-02978-w","volume":"25","author":"MU Rahman","year":"2025","unstructured":"Rahman MU, Direkoglu C (2025) A hybrid approach for binary and multi-class classification of voice disorders using a pre-trained model and ensemble classifiers. BMC Med Inform Decis Mak 25(1):177. https:\/\/doi.org\/10.1186\/s12911-025-02978-w","journal-title":"BMC Med Inform Decis Mak"},{"key":"10278_CR11","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1111\/his.13969","volume":"76","author":"G Brescia","year":"2020","unstructured":"Brescia G, Alessandrini L, Giacomelli L, Parrino D, Zanotti C, Tealdo G, Franz L, Carraro V, Barion U, Marioni G (2020) A classification of chronic rhinosinusitis with nasal polyps based on structured histopathology. Histopathology 76:296\u2013307. https:\/\/doi.org\/10.1111\/his.13969","journal-title":"Histopathology"},{"key":"10278_CR12","doi-asserted-by":"publisher","first-page":"2129","DOI":"10.1002\/hed.26152","volume":"42","author":"L Franz","year":"2020","unstructured":"Franz L, Tealdo G, Contro G, Bandolin L, Carraro V, Giacomelli L, Alessandrini L, Blandamura S, Marioni G (2020) Biological tumor markers (maspin, CD105, nm23-H1) and disease relapse in laryngeal cancer: cluster analysis. Head Neck 42:2129\u20132136. https:\/\/doi.org\/10.1002\/hed.26152","journal-title":"Head Neck"},{"key":"10278_CR13","first-page":"247","volume":"119","author":"PH Dejonckere","year":"1998","unstructured":"Dejonckere PH, Remacle M, Fresnel-Elbaz E, Woisard V, Crevier L, Millet B (1998) Reliability and clinical relevance of perceptual evaluation of pathological voices. Rev Laryngol Otol Rhinol (Bord) 119:247\u2013248","journal-title":"Rev Laryngol Otol Rhinol (Bord)"},{"key":"10278_CR14","doi-asserted-by":"publisher","first-page":"263e17","DOI":"10.1016\/j.jvoice.2013.07.013","volume":"28","author":"S Forti","year":"2014","unstructured":"Forti S, Amico M, Zambarbieri A, Ciabatta A, Assi C, Pignataro L, Cantarella G (2014) Validation of the Italian Voice Handicap Index-10. J Voice 28:263e17\u2013263e22. https:\/\/doi.org\/10.1016\/j.jvoice.2013.07.013","journal-title":"J Voice"},{"key":"10278_CR15","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2024.104255","volume":"45","author":"L Franz","year":"2024","unstructured":"Franz L, Da Canal A, Tuon M, Defilippi R, Biscaro A, Pasian M, Lucchini E, Marioni G, de Filippis C (2024) Clinical effectiveness of telerehabilitation in voice therapy programs for dysphonia. Am J Otolaryngol 45:104255. https:\/\/doi.org\/10.1016\/j.amjoto.2024.104255","journal-title":"Am J Otolaryngol"},{"key":"10278_CR16","doi-asserted-by":"crossref","unstructured":"Everitt BS, Landau S, Leese M, Stahl D (2011) Cluster analysis, 5th edn. Wiley, Chichester","DOI":"10.1002\/9780470977811"},{"key":"10278_CR17","doi-asserted-by":"publisher","first-page":"3286","DOI":"10.1002\/lary.31272","volume":"134","author":"J Phillips","year":"2024","unstructured":"Phillips J, Murdin L, Khondoker M, Grant K, Shepstone L, Sims E, Rea P, Harcourt J (2024) Cluster analysis to identify clinical subtypes of M\u00e9ni\u00e8re\u2019s disease. Laryngoscope 134:3286\u20133292. https:\/\/doi.org\/10.1002\/lary.31272","journal-title":"Laryngoscope"},{"key":"10278_CR18","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.anai.2022.11.013","volume":"130","author":"C Li","year":"2023","unstructured":"Li C, Zhang B, Yan M, Li Y, Chen J, Nie Z, Guo Y, Shi J, Chen F (2023) Cluster analysis of patients with chronic rhinosinusitis and asthma after endoscopic sinus surgery. Ann Allergy Asthma Immunol 130:325-332.e7. https:\/\/doi.org\/10.1016\/j.anai.2022.11.013","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"9","key":"10278_CR19","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci12091221","volume":"12","author":"EW Beukes","year":"2022","unstructured":"Beukes EW, Chundu S, Ratinaud P, Andersson G, Manchaiah V (2022) Experiential characteristics among individuals with tinnitus seeking online psychological interventions: A cluster analysis. Brain Sci 12(9):1221. https:\/\/doi.org\/10.3390\/brainsci12091221","journal-title":"Brain Sci"},{"key":"10278_CR20","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1016\/j.jvoice.2020.09.012","volume":"36","author":"G de Freitas Valadares","year":"2022","unstructured":"de Freitas Valadares G, Occhi-Alexandre IGP, Teixeira LC (2022) Sense of coherence and coping strategies in patients with dysphonia. J Voice 36:802\u2013807. https:\/\/doi.org\/10.1016\/j.jvoice.2020.09.012","journal-title":"J Voice"},{"key":"10278_CR21","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1159\/000502772","volume":"72","author":"M Englert","year":"2020","unstructured":"Englert M, Mendoza V, Behlau M, De Bodt M (2020) GALP Qualifier Scale: Initial considerations to classify a voice problem. Folia Phoniatr Logop 72:402\u2013410. https:\/\/doi.org\/10.1159\/000502772","journal-title":"Folia Phoniatr Logop"},{"key":"10278_CR22","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1016\/j.jvoice.2011.01.002","volume":"26","author":"H Li","year":"2012","unstructured":"Li H, Huang Z, Hu R, Zhang L, Xu W (2012) Study on the simplified Chinese version of the voice handicap index. J Voice 26:365\u2013371. https:\/\/doi.org\/10.1016\/j.jvoice.2011.01.002","journal-title":"J Voice"},{"key":"10278_CR23","doi-asserted-by":"publisher","first-page":"5247","DOI":"10.1044\/2025_JSLHR-25-00270","volume":"68","author":"SR Bellavance","year":"2025","unstructured":"Bellavance SR, Johnson AM (2025) Acoustic and aerodynamic clusters within primary muscle tension dysphonia. J Speech Lang Hear Res 68:5247\u20135260. https:\/\/doi.org\/10.1044\/2025_JSLHR-25-00270","journal-title":"J Speech Lang Hear Res"},{"key":"10278_CR24","doi-asserted-by":"publisher","unstructured":"Gilman M, Petty B, Maira C, Pethan M, Wang L, Hapner ER, Johns MM 3rd (2017) Aerodynamic patterns in patients with voice disorders: a retrospective study. J Voice 31:545\u2013549. https:\/\/doi.org\/10.1016\/j.jvoice.2016.11.001","DOI":"10.1016\/j.jvoice.2016.11.001"},{"key":"10278_CR25","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1159\/000442000","volume":"67","author":"F Camarrone","year":"2015","unstructured":"Camarrone F, Ivanova A, Decoster W, de Jong F, van Hulle MM (2015) Stable voice clusters identified when using the maximum versus minimum intensity curve in the phonetogram. Folia Phoniatr Logop 67:259\u201366. https:\/\/doi.org\/10.1159\/000442000","journal-title":"Folia Phoniatr Logop"},{"key":"10278_CR26","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-06572-2","volume":"12","author":"D Surangsrirat","year":"2022","unstructured":"Surangsrirat D, Sri-Iesaranusorn P, Chaiyaroj A, Vateekul P, Bhidayasiri R (2022) Parkinson\u2019s disease severity clustering based on tapping activity on mobile device. Sci Rep 12:3142. https:\/\/doi.org\/10.1038\/s41598-022-06572-2","journal-title":"Sci Rep"},{"key":"10278_CR27","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1097\/MLG.0b013e3180306da1","volume":"117","author":"N Roy","year":"2007","unstructured":"Roy N, Stemple J, Merrill RM, Thomas L (2007) Epidemiology of voice disorders in the elderly: preliminary findings. Laryngoscope 117:628\u201333. https:\/\/doi.org\/10.1097\/MLG.0b013e3180306da1","journal-title":"Laryngoscope"},{"key":"10278_CR28","doi-asserted-by":"publisher","first-page":"458","DOI":"10.14639\/0392-100X-N2018","volume":"42","author":"MR Marchese","year":"2022","unstructured":"Marchese MR, Longobardi Y, Di Cesare T, Mari G, Terruso V, Galli J, D\u2019Alatri L (2022) Gender-related differences in the prevalence of voice disorders and awareness of dysphonia. Acta Otorhinolaryngol Ital 42:458\u2013464. https:\/\/doi.org\/10.14639\/0392-100X-N2018","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"10278_CR29","doi-asserted-by":"publisher","first-page":"21","DOI":"10.3109\/14015439.2010.528022","volume":"36","author":"G Cantarella","year":"2011","unstructured":"Cantarella G, Baracca G, Pignataro L, Forti S (2011) Assessment of dysphonia due to benign vocal fold lesions by acoustic and aerodynamic indices: a multivariate analysis. Logoped Phoniatr Vocol 36:21\u201327. https:\/\/doi.org\/10.3109\/14015439.2010.528022","journal-title":"Logoped Phoniatr Vocol"},{"key":"10278_CR30","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.jvoice.2009.07.002","volume":"25","author":"M Brockmann","year":"2011","unstructured":"Brockmann M, Drinnan MJ, Storck C, Carding PN (2011) Reliable jitter and shimmer measurements in voice clinics: the relevance of vowel, gender, vocal intensity, and fundamental frequency effects in a typical clinical task. J Voice 25:44\u201353. https:\/\/doi.org\/10.1016\/j.jvoice.2009.07.002","journal-title":"J Voice"},{"key":"10278_CR31","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/j.jvoice.2010.10.002","volume":"25","author":"J Maslan","year":"2011","unstructured":"Maslan J, Leng X, Rees C, Blalock D, Butler SG (2011) Maximum phonation time in healthy older adults. J Voice 25:709\u201313. https:\/\/doi.org\/10.1016\/j.jvoice.2010.10.002","journal-title":"J Voice"},{"key":"10278_CR32","doi-asserted-by":"publisher","first-page":"4808","DOI":"10.1002\/lary.32436","volume":"135","author":"T Hasegawa","year":"2025","unstructured":"Hasegawa T, Aluariachy L, Fujita R, Watanabe Y (2025) Predictors of voice improvement after intracordal trafermin injection in vocal fold paralysis. Laryngoscope 135:4808\u20134814. https:\/\/doi.org\/10.1002\/lary.32436","journal-title":"Laryngoscope"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-026-10278-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-026-10278-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-026-10278-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T20:06:29Z","timestamp":1784664389000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-026-10278-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,1]]},"references-count":32,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10278"],"URL":"https:\/\/doi.org\/10.1007\/s00405-026-10278-w","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,1]]},"assertion":[{"value":"11 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 June 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors have no competing interests to declare that are relevant to the content of this article.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}