{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:10:53Z","timestamp":1792782653387,"version":"4.5.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Ondokuz May\u0131s University","id":[{"id":"https:\/\/ror.org\/028k5qw24","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine whether women with polycystic ovary syndrome (PCOS) exhibit hearing loss and if so, to identify the specific frequencies involved using extended high-frequency audiometry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single-centre, prospective, cross-sectional case-control study included 39 women with PCOS (diagnosed according to the Rotterdam criteria) and 39 age-matched controls. All participants underwent otoscopic examination, tympanometry, conventional pure-tone audiometry (250\u20138,000\u00a0Hz), and extended high-frequency audiometry (up to 12,500\u00a0Hz). Speech reception thresholds (SRT) and speech discrimination (SD) scores were also tested.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      No statistically significant between-group differences were detected at 1,000\u20138,000\u00a0Hz. Women with PCOS demonstrated significantly elevated thresholds at 250\u00a0Hz and 500\u00a0Hz in both ears (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), and at 11,200\u00a0Hz (right:\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004; left:\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and 12,500\u00a0Hz (left:\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008). SRT was significantly higher in the PCOS group in the right and left ears. (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.020 and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002 respectively). Speech discrimination scores were significantly lower in the PCOS group bilaterally (right:\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.036; left:\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Women with PCOS exhibit detectable but subclinical alterations in extended high-frequency hearing and speech performance despite normal conventional audiometric thresholds. The frequency-specific pattern of threshold elevation is consistent with cochlear involvement potentially mediated by metabolic, inflammatory, and hyperandrogenic mechanisms. Extended high-frequency audiometry may serve as a sensitive tool for detecting early auditory dysfunction in women with PCOS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00405-026-10304-x","type":"journal-article","created":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T03:27:30Z","timestamp":1779334050000},"page":"5565-5572","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Subclinical hearing loss in women with polycystic ovary syndrome: a case-control study using extended high-frequency audiometry"],"prefix":"10.1007","volume":"283","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5219-0542","authenticated-orcid":false,"given":"Emel","family":"Tahir","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4369-727X","authenticated-orcid":false,"given":"Asuman","family":"K\u00fc\u00e7\u00fck\u00f6ner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9760-7404","authenticated-orcid":false,"given":"Ula\u015f","family":"\u00c7oban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,21]]},"reference":[{"issue":"12","key":"10304_CR1","doi-asserted-by":"publisher","first-page":"2841","DOI":"10.1093\/humrep\/dew218","volume":"31","author":"G Bozdag","year":"2016","unstructured":"Bozdag G, Mumusoglu S, Zengin D, Karabulut E, Yildiz BO (2016) The prevalence and phenotypic features of polycystic ovary syndrome: a systematic review and meta-analysis. 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After using these tools, the author(s) reviewed and edited the content as needed and take(s) full responsibility for the integrity and accuracy of the final manuscript.","order":1,"name":"Ethics","label":"Generative AI and AI-assisted technologies in the writing process","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The data was submitted to the journal as supplementary material and share upon request. The data that support the findings of this study are openly available in Mendeley Data Storage as; Tahir, Emel (2026), \u201cpcos hearing\u201d, Mendeley Data, V1, doi:\n                      \n                      .","order":2,"name":"Ethics","label":"Data transparency","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declared no conflicts of interest.","order":3,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}