{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:05:28Z","timestamp":1790337928212,"version":"4.1.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T00:00:00Z","timestamp":1784419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T00:00:00Z","timestamp":1784419200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1007\/s00405-026-10393-8","type":"journal-article","created":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T21:48:02Z","timestamp":1784497682000},"page":"6255-6260","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Virtual reality stimulation modulates saccular activity and vestibular system responses"],"prefix":"10.1007","volume":"283","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3195-729X","authenticated-orcid":false,"given":"Dilara","family":"D\u00fcndar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1884-0246","authenticated-orcid":false,"given":"O\u011fuz","family":"Y\u0131lmaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,19]]},"reference":[{"key":"10393_CR1","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1097\/MRR.0000000000000244","volume":"40","author":"A Micarelli","year":"2017","unstructured":"Micarelli A, Viziano A, Augimeri I et al (2017) Three-dimensional head-mounted gaming task procedure maximizes effects of vestibular rehabilitation in unilateral vestibular hypofunction: a randomized controlled pilot trial. Int J Rehabil Res 40:325\u2013332","journal-title":"Int J Rehabil Res"},{"key":"10393_CR2","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1016\/j.apmr.2015.02.032","volume":"96","author":"D Meldrum","year":"2015","unstructured":"Meldrum D, Herdman S, Vance R et al (2015) Effectiveness of conventional versus virtual reality\u2013based balance exercises in vestibular rehabilitation for unilateral peripheral vestibular loss: results of a randomized controlled trial. Arch Phys Med Rehabil 96:1319\u20131328","journal-title":"Arch Phys Med Rehabil"},{"key":"10393_CR3","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1177\/0269215513509389","volume":"28","author":"V Booth","year":"2014","unstructured":"Booth V, Masud T, Connell L, Bath-Hextall F (2014) The effectiveness of virtual reality interventions in improving balance in adults with impaired balance compared with standard or no treatment: a systematic review and meta-analysis. Clin Rehabil 28:419\u2013431","journal-title":"Clin Rehabil"},{"key":"10393_CR4","doi-asserted-by":"publisher","first-page":"409","DOI":"10.3233\/VES-180647","volume":"28","author":"O Rosiak","year":"2019","unstructured":"Rosiak O, Krajewski K, Woszczak M, Jozefowicz-Korczynska M (2019) Evaluation of the effectiveness of a virtual reality-based exercise program for unilateral peripheral vestibular deficit. J Vestib Res 28:409\u2013415","journal-title":"J Vestib Res"},{"key":"10393_CR5","first-page":"57","volume-title":"Temel Odyoloji","author":"E H\u0131zal","year":"2017","unstructured":"H\u0131zal E (2017) Vestib\u00fcler Sistemin Anatomi ve Fizyolojisi. Temel Odyoloji, 2nd edn. G\u00fcne\u015f T\u0131p Kitabevleri, Ankara, pp 57\u201366","edition":"2"},{"key":"10393_CR6","unstructured":"Baloh RW, Honrubia V, Kerber KA (2010) Baloh and Honrubia\u2019s clinical neurophysiology of the vestibular system"},{"key":"10393_CR7","first-page":"1","volume":"137","author":"H Kingma","year":"2016","unstructured":"Kingma H, Van de Berg R (2016) Anatomy, physiology, and physics of the peripheral vestibular system. Handb Clin Neurol 137:1\u201316","journal-title":"Handb Clin Neurol"},{"key":"10393_CR8","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1111\/nyas.12585","volume":"1343","author":"M Dieterich","year":"2015","unstructured":"Dieterich M, Brandt T (2015) The bilateral central vestibular system: its pathways, functions, and disorders. Ann N Y Acad Sci 1343:10\u201326","journal-title":"Ann N Y Acad Sci"},{"key":"10393_CR9","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/B978-0-444-63916-5.00002-1","volume":"159","author":"RJ Peterka","year":"2018","unstructured":"Peterka RJ (2018) Sensory integration for human balance control. Handb Clin Neurol 159:27\u201342","journal-title":"Handb Clin Neurol"},{"key":"10393_CR10","doi-asserted-by":"publisher","first-page":"2483","DOI":"10.1007\/s00221-014-3973-2","volume":"232","author":"CM Oman","year":"2014","unstructured":"Oman CM, Cullen KE (2014) Brainstem processing of vestibular sensory exafference: implications for motion sickness etiology. Exp Brain Res 232:2483\u20132492","journal-title":"Exp Brain Res"},{"key":"10393_CR11","doi-asserted-by":"publisher","first-page":"4003","DOI":"10.1038\/s41467-024-48376-0","volume":"15","author":"OA Zobeiri","year":"2024","unstructured":"Zobeiri OA, Cullen KE (2024) Cerebellar Purkinje cells combine sensory and motor information to predict the sensory consequences of active self-motion in macaques. Nat Commun 15:4003","journal-title":"Nat Commun"},{"key":"10393_CR12","doi-asserted-by":"publisher","first-page":"193","DOI":"10.3389\/fpsyg.2015.00193","volume":"6","author":"S Palmisano","year":"2015","unstructured":"Palmisano S, Allison RS, Schira MM, Barry RJ (2015) Future challenges for vection research: definitions, functional significance, measures, and neural bases. Front Psychol 6:193","journal-title":"Front Psychol"},{"key":"10393_CR13","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1111\/j.1749-6632.1999.tb09193.x","volume":"871","author":"T Brandt","year":"1999","unstructured":"Brandt T, Dieterich M (1999) The vestibular cortex: its locations, functions, and disorders. Ann N Y Acad Sci 871:293\u2013312","journal-title":"Ann N Y Acad Sci"},{"key":"10393_CR14","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/j.anl.2015.12.006","volume":"43","author":"T Murofushi","year":"2016","unstructured":"Murofushi T (2016) Clinical application of vestibular evoked myogenic potential (VEMP). Auris Nasus Larynx 43:367\u2013376","journal-title":"Auris Nasus Larynx"},{"key":"10393_CR15","doi-asserted-by":"publisher","first-page":"3557","DOI":"10.1111\/ejn.14499","volume":"50","author":"M Gallagher","year":"2019","unstructured":"Gallagher M, Dowsett R, Ferr\u00e8 ER (2019) Vection in virtual reality modulates vestibular-evoked myogenic potentials. Eur J Neurosci 50:3557\u20133565","journal-title":"Eur J Neurosci"},{"key":"10393_CR16","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1068\/p5806","volume":"37","author":"S Palmisano","year":"2008","unstructured":"Palmisano S, Allison RS, Pekin F (2008) Accelerating self-motion displays produce more compelling vection in depth. Perception 37:22\u201333","journal-title":"Perception"},{"key":"10393_CR17","unstructured":"Hettinger LJ (2002) Illusory self-motion in virtual environments. In: Hale KS, Stanney KM (eds) Handbook of virtual environments. CRC, pp 511\u2013532"},{"key":"10393_CR18","doi-asserted-by":"publisher","first-page":"2141","DOI":"10.1007\/s00221-021-06123-7","volume":"239","author":"AN Bonsu","year":"2021","unstructured":"Bonsu AN, Nousi S, Lobo R et al (2021) Vestibulo-perceptual influences upon the vestibulo-spinal reflex. Exp Brain Res 239:2141\u20132149","journal-title":"Exp Brain Res"},{"key":"10393_CR19","doi-asserted-by":"publisher","first-page":"152","DOI":"10.7874\/jao.2021.00080","volume":"25","author":"\u015eT \u00d6zt\u00fcrk","year":"2021","unstructured":"\u00d6zt\u00fcrk \u015eT, \u015eerbet\u00e7io\u011flu MB, Ersin K, Y\u0131lmaz O (2021) The impact of optical illusions on the vestibular system. J Audiol Otol 25:152","journal-title":"J Audiol Otol"},{"key":"10393_CR20","doi-asserted-by":"crossref","unstructured":"P\u00f6hlmann KM, Li G, Wilson G et al (2024) Is Video Gaming a Cure for Cybersickness? Gamers Experience Less Cybersickness Than Non-Gamers in a VR Self-Motion Task. IEEE Trans Vis Comput Graph","DOI":"10.1109\/TVCG.2024.3456176"},{"key":"10393_CR21","doi-asserted-by":"publisher","first-page":"077","DOI":"10.3766\/jaaa.24.2.2","volume":"24","author":"JM Bogle","year":"2013","unstructured":"Bogle JM, Zapala DA, Criter R, Burkard R (2013) The effect of muscle contraction level on the cervical vestibular evoked myogenic potential (cVEMP): usefulness of amplitude normalization. J Am Acad Audiol 24:077\u2013088","journal-title":"J Am Acad Audiol"},{"key":"10393_CR22","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1006\/nimg.2002.1181","volume":"16","author":"A Kleinschmidt","year":"2002","unstructured":"Kleinschmidt A, Thilo KV, B\u00fcchel C et al (2002) Neural correlates of visual-motion perception as object-or self-motion. NeuroImage 16:873\u2013882","journal-title":"NeuroImage"},{"key":"10393_CR23","doi-asserted-by":"crossref","unstructured":"Kirollos R (2014) The Neural Correlates of Vection: an fMRI study","DOI":"10.1167\/15.12.1007"},{"key":"10393_CR24","doi-asserted-by":"publisher","first-page":"775","DOI":"10.3389\/fpsyg.2015.00775","volume":"6","author":"M Uesaki","year":"2015","unstructured":"Uesaki M, Ashida H (2015) Optic-flow selective cortical sensory regions associated with self-reported states of vection. Front Psychol 6:775","journal-title":"Front Psychol"},{"key":"10393_CR25","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1113\/jphysiol.2010.194720","volume":"589","author":"DE Angelaki","year":"2011","unstructured":"Angelaki DE, Gu Y, DeAngelis GC (2011) Visual and vestibular cue integration for heading perception in extrastriate visual cortex. J Physiol 589:825\u2013833","journal-title":"J Physiol"},{"key":"10393_CR26","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1038\/nn.2191","volume":"11","author":"Y Gu","year":"2008","unstructured":"Gu Y, Angelaki DE, DeAngelis GC (2008) Neural correlates of multisensory cue integration in macaque MSTd. Nat Neurosci 11:1201\u20131210","journal-title":"Nat Neurosci"},{"key":"10393_CR27","doi-asserted-by":"publisher","first-page":"329","DOI":"10.21053\/ceo.2019.00983","volume":"12","author":"J-J Song","year":"2019","unstructured":"Song J-J (2019) Virtual reality for vestibular rehabilitation. Clin Exp Otorhinolaryngol 12:329","journal-title":"Clin Exp Otorhinolaryngol"},{"key":"10393_CR28","first-page":"e930182","volume":"27","author":"T Stankiewicz","year":"2020","unstructured":"Stankiewicz T, Gujski M, Niedzielski A, Chmielik LP (2020) Virtual reality vestibular rehabilitation in 20 patients with vertigo due to peripheral vestibular dysfunction. Med Sci Monit Int Med J Exp Clin Res 27:e930182\u2013e930181","journal-title":"Med Sci Monit Int Med J Exp Clin Res"},{"key":"10393_CR29","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1097\/MAO.0000000000003155","volume":"42","author":"M Xie","year":"2021","unstructured":"Xie M, Zhou K, Patro N et al (2021) Virtual reality for vestibular rehabilitation: a systematic review. Otol Neurotol 42:967\u2013977","journal-title":"Otol Neurotol"},{"key":"10393_CR30","doi-asserted-by":"publisher","first-page":"107","DOI":"10.5606\/Tr-ENT.2019.55264","volume":"29","author":"O Y\u0131lmaz","year":"2019","unstructured":"Y\u0131lmaz O, \u00d6zt\u00fcrk \u015eT, \u015eerbet\u00e7io\u011flu MB (2019) Isolated otolithic dysfunction and vestibular rehabilitation results: A case report. Turk J Ear Nose Throat 29:107\u2013110","journal-title":"Turk J Ear Nose Throat"}],"container-title":["European Archives of Oto-Rhino-Laryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-026-10393-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00405-026-10393-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00405-026-10393-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T11:57:06Z","timestamp":1790337426000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00405-026-10393-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,19]]},"references-count":30,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10393"],"URL":"https:\/\/doi.org\/10.1007\/s00405-026-10393-8","relation":{},"ISSN":["0937-4477","1434-4726"],"issn-type":[{"value":"0937-4477","type":"print"},{"value":"1434-4726","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,19]]},"assertion":[{"value":"18 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 June 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"\u0130stanbul Medipol University Clinical Research Ethics Committee, the decision 07.06.2021\/576. An informed consent form was obtained from the participants who volunteered to participate in the study. The study was conducted following the ethical principles specified in the Declaration of Helsinki.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Yes.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}