{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:11:07Z","timestamp":1792782667180,"version":"4.5.0"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T00:00:00Z","timestamp":1784419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T00:00:00Z","timestamp":1784419200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e0 degli Studi di Palermo","id":[{"id":"https:\/\/ror.org\/044k9ta02","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sinonasal Schneiderian papillomas are uncommon epithelial tumors. Although benign, they may behave aggressively, recur after incomplete resection, and, particularly in the inverted subtype, be associated with carcinoma. Endoscopic surgery is now widely used when the site of attachment can be adequately exposed and treated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To review recurrence, morbidity, attachment-site documentation, and metachronous carcinoma in a single-surgeon endoscopic series of sinonasal Schneiderian papillomas treated with an attachment-site-oriented technique.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively reviewed 71 patients with histologically confirmed Schneiderian papilloma treated exclusively by endoscopic surgery between January 2017 and December 2023. Preoperative work-up included nasal endoscopy, CT, and MRI. Disease extent was classified according to the Krouse system. Surgery was planned according to tumor extension and the suspected attachment site. Follow-up was based on serial endoscopic examinations; annual MRI was advised for long-term surveillance. Median follow-up was 46 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Krouse staging identified 3 T1, 24 T2, 40 T3, and 4 T4 lesions. Histology included 58 inverted, 8 exophytic, and 5 oncocytic papillomas. Recurrence occurred in 3 patients (4.2%), all with inverted papilloma and advanced-stage disease (T3\u2013T4). Complications were observed in 4 patients (5.6%), including three arterial bleeding episodes and one cerebrospinal fluid leak. One patient developed metachronous squamous cell carcinoma during follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this single-surgeon series, attachment-site-oriented endoscopic surgery was followed by few recurrences and acceptable morbidity during the available follow-up. Recurrences were observed only in advanced-stage inverted papillomas. These findings support careful treatment of the attachment site and long-term surveillance, while remaining limited by the retrospective design and heterogeneous follow-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00405-026-10420-8","type":"journal-article","created":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T21:41:58Z","timestamp":1784497318000},"page":"6479-6483","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Endoscopic surgical treatment of sinonasal Schneiderian papillomas: our experience"],"prefix":"10.1007","volume":"283","author":[{"given":"Salvatore","family":"Poma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Comparetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domiziana","family":"Picone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonino","family":"Milia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerio","family":"Patti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Sergi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuffaro","family":"Luana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2016-4101","authenticated-orcid":false,"given":"Domenico Michele","family":"Modica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Fucarino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Pitruzzella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,19]]},"reference":[{"key":"10420_CR1","volume-title":"Head and neck tumours","author":"WHO Classification of Tumours Editorial Board","year":"2024","unstructured":"WHO Classification of Tumours Editorial Board (2024) Head and neck tumours, vol 9, 5th edn. 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J Laryngol Otol 124:705\u2013715. https:\/\/doi.org\/10.1017\/S0022215110000599","journal-title":"J Laryngol Otol"},{"key":"10420_CR4","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1016\/j.otc.2006.01.005","volume":"39","author":"CT Melroy","year":"2006","unstructured":"Melroy CT, Senior BA (2006) Benign sinonasal neoplasms: a focus on inverting papilloma. Otolaryngol Clin North Am 39:601\u2013617. https:\/\/doi.org\/10.1016\/j.otc.2006.01.005","journal-title":"Otolaryngol Clin North Am"},{"key":"10420_CR5","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1097\/01.moo.0000193175.54450.1f","volume":"14","author":"AP Lane","year":"2006","unstructured":"Lane AP, Bolger WE (2006) Endoscopic management of inverted papilloma. Curr Opin Otolaryngol Head Neck Surg 14:14\u201318. https:\/\/doi.org\/10.1097\/01.moo.0000193175.54450.1f","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"10420_CR6","doi-asserted-by":"publisher","first-page":"75","DOI":"10.2500\/ajra.2014.28.3985","volume":"28","author":"F Pagella","year":"2014","unstructured":"Pagella F, Pusateri A, Giourgos G et al (2014) Evolution in the treatment of sinonasal inverted papilloma: pedicle-oriented endoscopic surgery. Am J Rhinol Allergy 28:75\u201381. https:\/\/doi.org\/10.2500\/ajra.2014.28.3985","journal-title":"Am J Rhinol Allergy"},{"key":"10420_CR7","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/s40463-018-0271-1","volume":"47","author":"V Wu","year":"2018","unstructured":"Wu V, Siu J, Yip J, Lee JM (2018) Endoscopic management of maxillary sinus inverted papilloma attachment sites to minimize disease recurrence. 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The study protocol was reviewed and approved by the Local Ethics Committee Palermo 2 (Protocol No. 2 AOR 09\/01\/2026).","order":3,"name":"Ethics","label":"Consent to publish","group":{"name":"EthicsHeading","label":"Declarations"}}]}}