{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:10:21Z","timestamp":1792782621753,"version":"4.5.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Private Universit\u00e4t Witten\/Herdecke gGmbH","id":[{"id":"https:\/\/ror.org\/00yq55g44","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Otorhinolaryngol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This study aims to characterize hospitalization-level morbidity and care burden associated with oropharyngeal carcinoma (OPC) in Germany and assess the contribution of terminology-based extraction from narrative electronic health record (EHR) documentation beyond structured administrative coding.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This nationwide retrospective observational study analyzed inpatient data from 96 German tertiary care hospitals (2016\u20132022). OPC hospitalizations were identified using ICD-10-GM principal diagnosis codes. Treatment patterns, morbidity indicators, and resource utilization measures were derived from OPS procedural codes, structured clinical variables, and terminology-based extraction from predefined narrative EHR sections. Analyses were conducted at the hospitalization level.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 13,925 OPC hospitalizations, major pharyngeal resections were documented in 9.0% of cases. The proportion reconstructed with microvascular free flaps more than doubled, while resections without reconstruction declined. Robotic-assisted surgery was documented in 0.1% of OPC hospitalizations. Mechanical ventilation was documented in 3.7% of cases, and 19.7% had documentation indicative of tracheostomy. Median hemoglobin decreased during hospitalization, and documented RBC transfusion use increased descriptively from 5.4% in 2016 to 7.6% in 2022. The in-hospital mortality rate was 2.8%. Terminology-based EHR extraction identified additional documentation of selected comorbidities and morbidity markers beyond structured coding alone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Hospitalization-level OPC care in German tertiary hospitals involves substantial inpatient care burden, including complex reconstruction, airway-related morbidity, and physiologic morbidity markers. Combining structured administrative data with terminology-based extraction from narrative EHR documentation provided additional routine-data markers beyond coding alone. These findings should be interpreted as complementary hospitalization-level information rather than as validated clinical endpoints or evidence of causal treatment effects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00405-026-10583-4","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:19:45Z","timestamp":1789604385000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Inpatient morbidity and structural care burden in oropharyngeal carcinoma in Germany: a nationwide cross-institutional EHR analysis using an AI-enabled data network"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7877-7977","authenticated-orcid":false,"given":"Sabine","family":"Eichhorn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"St\u00f6ckert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz Niklas","family":"Mitze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Bucksch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eren","family":"Erdogan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inga Marte Charlott","family":"Seuthe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Dastur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas Jae-Hyun","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,17]]},"reference":[{"issue":"5","key":"10583_CR1","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1002\/hed.22015","volume":"35","author":"H Mehanna","year":"2013","unstructured":"Mehanna H, Beech T, Nicholson T, El-Hariry I, McConkey C, Paleri V, Roberts S (2013) Prevalence of human papillomavirus in oropharyngeal and nonoropharyngeal head and neck cancer\u2013systematic review and meta-analysis of trends by time and region. 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Tiplu GmbH administers data access within the geNuGes project framework. All other authors declare that they have no financial interests. Non-financial interests: The authors declare no non-financial interests.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}