{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:58:42Z","timestamp":1791475122798,"version":"4.3.4"},"reference-count":69,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2009,7,2]],"date-time":"2009-07-02T00:00:00Z","timestamp":1246492800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Arch Psychiatry Clin Neurosci"],"published-print":{"date-parts":[[2009,10]]},"DOI":"10.1007\/s00406-009-0026-0","type":"journal-article","created":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T14:17:42Z","timestamp":1246457862000},"page":"383-393","source":"Crossref","is-referenced-by-count":92,"title":["Cannabis use in pregnancy and early life and its consequences: animal models"],"prefix":"10.1007","volume":"259","author":[{"given":"Miriam","family":"Schneider","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2009,7,2]]},"reference":[{"key":"26_CR1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0163-1047(80)90469-0","volume":"29","author":"EL Abel","year":"1980","unstructured":"Abel EL (1980) Prenatal exposure to cannabis: a critical review of effects on growth, development, and behavior. Behav Neural Biol 29:137\u2013156","journal-title":"Behav Neural Biol"},{"key":"26_CR2","volume-title":"Marihuana, tobacco, alcohol and reproduction","author":"EL Abel","year":"1983","unstructured":"Abel EL (1983) Marihuana, tobacco, alcohol and reproduction. CRC Press, Boca Raton"},{"key":"26_CR3","doi-asserted-by":"crossref","first-page":"353","DOI":"10.3758\/BF03329476","volume":"4","author":"EL Abel","year":"1979","unstructured":"Abel EL, Day N, Dintcheff BA, Ernst CAS (1979) Inhibition of postnatal maternal performance in rats treated with marijuana extract during pregnancy. Bull Psychon Soc 4:353\u2013359","journal-title":"Bull Psychon Soc"},{"key":"26_CR4","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1093\/cercor\/bhi076","volume":"15","author":"T Antonelli","year":"2005","unstructured":"Antonelli T, Tomasini MC, Tattoli M, Cassano T, Tanganelli S, Finetti S, Mazzoni E, Trabace L, Steardo L, Cuomo V, Ferraro L (2005) Prenatal exposure to the CB1 receptor agonist WIN 55, 212\u20132 causes learning disruption associated with impaired cortical NMDA receptor function and emotional reactivity changes in rat offspring. Cereb Cortex 15:2013\u20132020","journal-title":"Cereb Cortex"},{"key":"26_CR5","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.neuropharm.2008.01.006","volume":"54","author":"M Biscaia","year":"2008","unstructured":"Biscaia M, Fernandez B, Higuera-Matas A, Miguens M, Viveros MP, Garcia-Lecumberri C, Ambrosio E (2008) Sex-dependent effects of periadolescent exposure to the c cannabinoid agonist CP-55, 940 on morphine self-administration behaviour and the endogenous opioid system. Neuropharmacology 54:863\u2013873","journal-title":"Neuropharmacology"},{"key":"26_CR6","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s00213-003-1550-7","volume":"170","author":"M Biscaia","year":"2003","unstructured":"Biscaia M, Marin S, Fernandez B, Marco EM, Rubio M, Guaza C, Ambrosio E, Viveros MP (2003) Chronic treatment with CP 55, 940 during the peri-adolescent period differentially affects the behavioural responses of male and female rats in adulthood. Psychopharmacology 170:301\u2013308","journal-title":"Psychopharmacology"},{"key":"26_CR7","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/0003-3472(64)90062-4","volume":"12","author":"RC Bolles","year":"1964","unstructured":"Bolles RC, Woods PJ (1964) The ontogeny of behaviour in the albino rat. Anim Behav 12:427\u2013441","journal-title":"Anim Behav"},{"key":"26_CR8","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.ejphar.2005.12.017","volume":"531","author":"M Bortolato","year":"2006","unstructured":"Bortolato M, Frau R, Orru M, Casti A, Aru GN, Fa M, Manunta M, Usai A, Mereu G, Gessa GL (2006) Prenatal exposure to a cannabinoid receptor agonist does not affect sensorimotor gating in rats. Eur J Pharmacol 531:166\u2013170","journal-title":"Eur J Pharmacol"},{"key":"26_CR9","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1126\/science.166.3905.635","volume":"166","author":"BA Campbell","year":"1969","unstructured":"Campbell BA, Lytle LD, Fibiger HC (1969) Ontogeny of adrenergic arousal and cholinergic inhibitory mechanisms in the rat. Science 166:635\u2013637","journal-title":"Science"},{"key":"26_CR10","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1111\/j.1369-1600.2007.00074.x","volume":"12","author":"P Campolongo","year":"2007","unstructured":"Campolongo P, Trezza V, Cassano T, Gaetani S, Morgese MG, Ubaldi M, Soverchia L, Antonelli T, Ferraro L, Massi M, Ciccocioppo R, Cuomo V (2007) Perinatal exposure to delta-9-tetrahydrocannabinol causes enduring cognitive deficits associated with alteration of cortical gene expression and neurotransmission in rats. Addict Biol 12:485\u2013495","journal-title":"Addict Biol"},{"key":"26_CR11","first-page":"345","volume":"8","author":"SL Dalterio","year":"1986","unstructured":"Dalterio SL (1986) Cannabinoid exposure: effects on development. Neurobehav Toxicol Teratol 8:345\u2013352","journal-title":"Neurobehav Toxicol Teratol"},{"key":"26_CR12","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0378-3782(79)90022-7","volume":"3","author":"J Dobbing","year":"1979","unstructured":"Dobbing J, Sands J (1979) Comparative aspects of the brain growth spurt. Early Hum Dev 3:79\u201383","journal-title":"Early Hum Dev"},{"key":"26_CR13","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.taap.2007.05.008","volume":"223","author":"D Economidou","year":"2007","unstructured":"Economidou D, Mattioli L, Ubaldi M, Lourdusamy A, Soverchia L, Hardiman G, Campolongo P, Cuomo V, Ciccocioppo R (2007) Role of cannabinoidergic mechanisms in ethanol self-administration and ethanol seeking in rat adult offspring following perinatal exposure to Delta9-tetrahydrocannabinol. Toxicol Appl Pharmacol 223:73\u201385","journal-title":"Toxicol Appl Pharmacol"},{"key":"26_CR14","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1038\/sj.npp.1301127","volume":"32","author":"M Ellgren","year":"2007","unstructured":"Ellgren M, Spano SM, Hurd YL (2007) Adolescent cannabis exposure alters opiate intake and opioid limbic neuronal populations in adult rats. Neuropsychopharmacology 32:607\u2013615","journal-title":"Neuropsychopharmacology"},{"key":"26_CR15","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.1523\/JNEUROSCI.4080-05.2006","volume":"26","author":"KA Fenoglio","year":"2006","unstructured":"Fenoglio KA, Chen Y, Baram TZ (2006) Neuroplasticity of the hypothalamic-pituitary- adrenal axis early in life requires recurrent recruitment of stress-regulating brain regions. J Neurosci 26:2434\u20132442","journal-title":"J Neurosci"},{"key":"26_CR16","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0166-2236(99)01491-5","volume":"23","author":"J Fernandez-Ruiz","year":"2000","unstructured":"Fernandez-Ruiz J, Berrendero F, Hernandez ML, Ramos JA (2000) The endogenous cannabinoid system and brain development. Trends Neurosci 23:14\u201320","journal-title":"Trends Neurosci"},{"key":"26_CR17","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/S0024-3205(99)00295-7","volume":"65","author":"JJ Fernandez-Ruiz","year":"1999","unstructured":"Fernandez-Ruiz JJ, Berrendero F, Hernandez ML, Romero J, Ramos JA (1999) Role of endocannabinoids in brain development. Life Sci 65:725\u2013736","journal-title":"Life Sci"},{"key":"26_CR18","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.ejphar.2004.07.033","volume":"500","author":"E Fride","year":"2004","unstructured":"Fride E (2004) The endocannabinoid-CB(1) receptor system in pre- and postnatal life. Eur J Pharmacol 500:289\u2013297","journal-title":"Eur J Pharmacol"},{"key":"26_CR19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0892-0362(00)00119-7","volume":"23","author":"PA Fried","year":"2001","unstructured":"Fried PA, Smith AM (2001) A literature review of the consequences of prenatal marihuana exposure\u2014an emerging theme of a deficiency in aspects of executive functions. Neurotoxicol Teratol 23:1\u201311","journal-title":"Neurotoxicol Teratol"},{"key":"26_CR20","first-page":"1","volume":"00","author":"E Garoflos","year":"2008","unstructured":"Garoflos E, Stamatakis A, Rafrogianni A, Pondiki S, Stylianopoulou F (2008) Neonatal handling on the first postnatal day leads to increased maternal behavior and fos levels in the brain of the newborn rat. Dev Psychobiol 00:1\u201310","journal-title":"Dev Psychobiol"},{"key":"26_CR21","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1152\/jn.2001.85.1.468","volume":"85","author":"G Gerdeman","year":"2001","unstructured":"Gerdeman G, Lovinger DM (2001) CB1 cannabinoid receptor inhibits synaptic release of glutamate in rat dorsolateral striatum. J Neurophysiol 85:468\u2013471","journal-title":"J Neurophysiol"},{"key":"26_CR22","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0091-3057(03)00115-1","volume":"75","author":"B Gonzalez","year":"2003","unstructured":"Gonzalez B, de Miguel R, Martin S, Perez-Rosado A, Romero J, Garcia-Lecumberri C, Fernandez-Ruiz J, Ramos JA, Ambrosio E (2003) Effects of perinatal exposure to delta 9-tetrahydrocannabinol on operant morphine-reinforced behavior. Pharmacol Biochem Behav 75:577\u2013584","journal-title":"Pharmacol Biochem Behav"},{"key":"26_CR23","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1111\/j.1749-6632.2000.tb06193.x","volume":"899","author":"AJ Hampson","year":"2000","unstructured":"Hampson AJ, Grimaldi M, Lolic M, Wink D, Rosenthal R, Axelrod J (2000) Neuroprotective antioxidants from marijuana. Ann N Y Acad Sci 899:274\u2013282","journal-title":"Ann N Y Acad Sci"},{"key":"26_CR24","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.tips.2006.12.004","volume":"28","author":"T Harkany","year":"2007","unstructured":"Harkany T, Guzman M, Galve-Roperh I, Berghuis P, Devi LA, Mackie K (2007) The emerging functions of endocannabinoid signaling during CNS development. Trends Pharmacol Sci 28:83\u201392","journal-title":"Trends Pharmacol Sci"},{"key":"26_CR25","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1111\/j.1469-7793.2001.0731e.x","volume":"532","author":"CC Huang","year":"2001","unstructured":"Huang CC, Lo SW, Hsu KS (2001) Presynaptic mechanisms underlying cannabinoid inhibition of excitatory synaptic transmission in rat striatal neurons. J Physiol 532:731\u2013748","journal-title":"J Physiol"},{"key":"26_CR26","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/0024-3205(89)90380-9","volume":"44","author":"DE Hutchings","year":"1989","unstructured":"Hutchings DE, Martin BR, Gamagaris Z, Miller N, Fico T (1989) Plasma concentrations of delta-9-tetrahydrocannabinol in dams and fetuses following acute or multiple prenatal dosing in rats. Life Sci 44:697\u2013701","journal-title":"Life Sci"},{"key":"26_CR27","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1126\/science.283.5398.70","volume":"283","author":"C Ikonomidou","year":"1999","unstructured":"Ikonomidou C, Bosch F, Miksa M, Bittigau P, Vockler J, Dikranian K, Tenkova TI, Stefovska V, Turski L, Olney JW (1999) Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain. Science 283:70\u201374","journal-title":"Science"},{"key":"26_CR28","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0014-2999(73)90018-6","volume":"22","author":"A Jakubovic","year":"1973","unstructured":"Jakubovic A, Hattori T, McGeer PL (1973) Radioactivity in suckled rats after giving 14 C- tetrahydrocannabinol to the mother. Eur J Pharmacol 22:221\u2013223","journal-title":"Eur J Pharmacol"},{"key":"26_CR29","doi-asserted-by":"crossref","first-page":"359","DOI":"10.2466\/pms.1980.50.2.359","volume":"50","author":"GF Kawash","year":"1980","unstructured":"Kawash GF, Yeung DL, Berg SD (1980) Effects of administration of cannabis resin during pregnancy on emotionality and learning in rats\u2019 offspring. Percept Mot Skills 50:359\u2013365","journal-title":"Percept Mot Skills"},{"key":"26_CR30","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0301-0082(89)90023-3","volume":"32","author":"B Kolb","year":"1989","unstructured":"Kolb B, Whishaw IQ (1989) Plasticity in the neocortex: mechanisms underlying recovery from early brain damage. Prog Neurobiol 32:235\u2013276","journal-title":"Prog Neurobiol"},{"key":"26_CR31","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/0006-8993(90)91322-8","volume":"525","author":"AM Kumar","year":"1990","unstructured":"Kumar AM, Haney M, Becker T, Thompson ML, Kream RM, Miczek K (1990) Effect of early exposure to delta-9-tetrahydrocannabinol on the levels of opioid peptides, gonadotropin-releasing hormone and substance P in the adult male rat brain. Brain Res 525:78\u201383","journal-title":"Brain Res"},{"key":"26_CR32","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1080\/10253890601056192","volume":"9","author":"J Lesage","year":"2006","unstructured":"Lesage J, Sebaai N, Leonhardt M, Dutriez-Casteloot I, Breton C, Deloof S, Vieau D (2006) Perinatal maternal undernutrition programs the offspring hypothalamo- pituitary-adrenal (HPA) axis. Stress 9:183\u2013198","journal-title":"Stress"},{"key":"26_CR33","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.psyneuen.2007.04.002","volume":"32","author":"R Llorente","year":"2007","unstructured":"Llorente R, Arranz L, Marco EM, Moreno E, Puerto M, Guaza C, De la Fuente M, Viveros MP (2007) Early maternal deprivation and neonatal single administration with a cannabinoid agonist induce long-term sex-dependent psychoimmunoendocrine effects in adolescent rats. Psychoneuroendocrinology 32:636\u2013650","journal-title":"Psychoneuroendocrinology"},{"key":"26_CR34","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1126\/science.168.3936.1159","volume":"168","author":"R Mechoulam","year":"1970","unstructured":"Mechoulam R (1970) Marihuana chemistry. Science 168:1159\u20131166","journal-title":"Science"},{"key":"26_CR35","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1002\/cbdv.200790147","volume":"4","author":"R Mechoulam","year":"2007","unstructured":"Mechoulam R, Peters M, Murillo-Rodriguez E, Hanus LO (2007) Cannabidiol\u2014recent advances. Chem Biodivers 4:1678\u20131692","journal-title":"Chem Biodivers"},{"key":"26_CR36","doi-asserted-by":"crossref","first-page":"4915","DOI":"10.1073\/pnas.0537849100","volume":"100","author":"G Mereu","year":"2003","unstructured":"Mereu G, Fa M, Ferraro L, Cagiano R, Antonelli T, Tattoli M, Ghiglieri V, Tanganelli S, Gessa GL, Cuomo V (2003) Prenatal exposure to a cannabinoid agonist produces memory deficits linked to dysfunction in hippocampal long-term potentiation and glutamate release. Proc Natl Acad Sci USA 100:4915\u20134920","journal-title":"Proc Natl Acad Sci USA"},{"key":"26_CR37","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/0892-0362(87)90023-7","volume":"9","author":"DJ Mokler","year":"1987","unstructured":"Mokler DJ, Robinson SE, Johnson JH, Hong JS, Rosecrans JA (1987) Neonatal administration of delta-9-tetrahydrocannabinol (THC) alters the neurochemical response to stress in the adult Fischer-344 rat. Neurotoxicol Teratol 9:321\u2013327","journal-title":"Neurotoxicol Teratol"},{"key":"26_CR38","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/j.1369-1600.2008.00104.x","volume":"13","author":"FA Moreira","year":"2008","unstructured":"Moreira FA, Lutz B (2008) The endocannabinoid system: emotion, learning and addiction. Addict Biol 13:196\u2013212","journal-title":"Addict Biol"},{"key":"26_CR39","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1097\/00008877-200509000-00015","volume":"16","author":"M Moreno","year":"2005","unstructured":"Moreno M, Escuredo L, Munoz R, Rodriguez dF, Navarro M (2005) Long-term behavioural and neuroendocrine effects of perinatal activation or blockade of CB1 cannabinoid receptors. Behav Pharmacol 16:423\u2013430","journal-title":"Behav Pharmacol"},{"key":"26_CR40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF02246436","volume":"122","author":"M Navarro","year":"1995","unstructured":"Navarro M, Rubio P, de Fonseca FR (1995) Behavioural consequences of maternal exposure to natural cannabinoids in rats. Psychopharmacology 122:1\u201314","journal-title":"Psychopharmacology"},{"key":"26_CR41","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1007\/BF02247471","volume":"116","author":"M Navarro","year":"1994","unstructured":"Navarro M, Rubio T, Rodriguez de Fonseca F (1994) Sex-dimorphic psychomotor activation after perinatal exposure to (-)-D9-tetrahadrocannabinol. An ontogenic study in Wistar rats. Psychopharmacology 116:414\u2013422","journal-title":"Psychopharmacology"},{"key":"26_CR42","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.ntt.2007.12.007","volume":"30","author":"RJ Newsom","year":"2008","unstructured":"Newsom RJ, Kelly SJ (2008) Perinatal delta-9-tetrahydrocannabinol exposure disrupts social and open field behavior in adult male rats. Neurotoxicol Teratol 30:213\u2013219","journal-title":"Neurotoxicol Teratol"},{"key":"26_CR43","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1097\/00008877-200509000-00019","volume":"16","author":"M O\u2019Shea","year":"2005","unstructured":"O\u2019Shea M, Mallet PE (2005) Impaired learning in adulthood following neonatal delta9- THC exposure. Behav Pharmacol 16:455\u2013461","journal-title":"Behav Pharmacol"},{"key":"26_CR44","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1177\/0269881106065188","volume":"20","author":"M O\u2019Shea","year":"2006","unstructured":"O\u2019Shea M, McGregor IS, Mallet PE (2006) Repeated cannabinoid exposure during perinatal, adolescent or early adult ages produces similar longlasting deficits in object recognition and reduced social interaction in rats. J Psychopharmacol 20:611\u2013621","journal-title":"J Psychopharmacol"},{"key":"26_CR45","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1177\/0269881104047277","volume":"18","author":"M O\u2019Shea","year":"2004","unstructured":"O\u2019Shea M, Singh ME, McGregor IS, Mallet PE (2004) Chronic cannabinoid exposure produces lasting memory impairment and increased anxiety in adolescent but not adult rats. J Psychopharmacol 18:502\u2013508","journal-title":"J Psychopharmacol"},{"key":"26_CR46","first-page":"363","volume-title":"The physiology of reproduction","author":"SR Ojeda","year":"1994","unstructured":"Ojeda SR, Urbanski HF (1994) Puberty in the rat. In: Knobil E, Neill JD (eds) The physiology of reproduction. Raven Press, New York, pp 363\u2013410"},{"key":"26_CR47","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1080\/13556210500123217","volume":"10","author":"FT Pijlman","year":"2005","unstructured":"Pijlman FT, Rigter SM, Hoek J, Goldschmidt HM, Niesink RJ (2005) Strong increase in total delta-THC in cannabis preparations sold in Dutch coffee shops. Addict Biol 10:171\u2013180","journal-title":"Addict Biol"},{"key":"26_CR48","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.biopsych.2004.05.006","volume":"56","author":"M Pistis","year":"2004","unstructured":"Pistis M, Perra S, Pillolla G, Melis M, Muntoni AL, Gessa GL (2004) Adolescent exposure to cannabinoids induces long-lasting changes in the response to drugs of abuse of rat midbrain dopamine neurons. Biol Psychiatry 56:86\u201394","journal-title":"Biol Psychiatry"},{"key":"26_CR49","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/j.1556-4029.2007.00603.x","volume":"53","author":"DJ Potter","year":"2008","unstructured":"Potter DJ, Clark P, Brown MB (2008) Potency of delta 9-THC and other cannabinoids in cannabis in England in 2005: implications for psychoactivity and pharmacology. J Forensic Sci 53:90\u201394","journal-title":"J Forensic Sci"},{"key":"26_CR50","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1038\/sj.npp.1301475","volume":"33","author":"HR Quinn","year":"2008","unstructured":"Quinn HR, Matsumoto I, Callaghan PD, Long LE, Arnold JC, Gunasekaran N, Thompson MR, Dawson B, Mallet PE, Kashem MA, Matsuda-Matsumoto H, Iwazaki T, McGregor IS (2008) Adolescent rats find repeated Delta(9)-THC less aversive than adult rats but display greater residual cognitive deficits and changes in hippocampal protein expression following exposure. Neuropsychopharmacology 33:1113\u20131126","journal-title":"Neuropsychopharmacology"},{"key":"26_CR51","doi-asserted-by":"crossref","first-page":"2760","DOI":"10.1038\/sj.npp.1301664","volume":"33","author":"T Rubino","year":"2008","unstructured":"Rubino T, Vigano\u2019 D, Realini N, Guidali C, Braida D, Capurro V, Castiglioni C, Cherubino F, Romualdi P, Candeletti S, Sala M, Parolaro D (2008) Chronic delta(9)- tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates. Neuropsychopharmacology 33:2760\u20132771","journal-title":"Neuropsychopharmacology"},{"key":"26_CR52","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0091-3057(98)00099-9","volume":"61","author":"P Rubio","year":"1998","unstructured":"Rubio P, Rodriguez de Fonseca F, Martin-Calderon JL, del Arco I, Bartolome S, Villanua MA, Navarro M (1998) Maternal exposure to low doses of delta9- tetrahydrocannabinol facilitates morphine-induced place conditioning in adult male offspring. Pharmacol Biochem Behav 61:229\u2013238","journal-title":"Pharmacol Biochem Behav"},{"key":"26_CR53","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1016\/0024-3205(95)00204-J","volume":"56","author":"P Rubio","year":"1995","unstructured":"Rubio P, Rodriguez de Fonseca F, Munoz RM, Ariznavarreta C, Martin-Calderon JL, Navarro M (1995) Long-term behavioral effects of perinatal exposure to delta 9- tetrahydrocannabinol in rats: possible role of pituitary\u2013adrenal axis. Life Sci 56:2169\u20132176","journal-title":"Life Sci"},{"issue":"2","key":"26_CR54","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/j.1369-1600.2008.00110.x","volume":"13","author":"M Schneider","year":"2008","unstructured":"Schneider M (2008) Puberty as a highly vulnerable developmental period for the consequences of cannabis exposure. Addict Biol 13(2):253\u2013263","journal-title":"Addict Biol"},{"key":"26_CR55","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1097\/00008877-200509000-00018","volume":"16","author":"M Schneider","year":"2005","unstructured":"Schneider M, Drews E, Koch M (2005) Behavioral effects in adult rats of chronic prepubertal treatment with the cannabinoid receptor agonist WIN 55, 212\u20132. Behav Pharmacol 16:447\u2013454","journal-title":"Behav Pharmacol"},{"key":"26_CR56","doi-asserted-by":"crossref","unstructured":"Schneider M, Koch M (2003) Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognition memory and the performance in a progressive ratio task in adult rats. Neuropsychopharmacology 28:1760\u20131769","DOI":"10.1038\/sj.npp.1300225"},{"key":"26_CR57","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1038\/sj.npp.1300634","volume":"30","author":"M Schneider","year":"2005","unstructured":"Schneider M, Koch M (2005) Deficient social and play behavior in juvenile and adult rats after neonatal cortical lesion: effects of chronic pubertal cannabinoid treatment. Neuropsychopharmacology 30:944\u2013957","journal-title":"Neuropsychopharmacology"},{"key":"26_CR58","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1369-1600.2008.00117.x","volume":"13","author":"M Schneider","year":"2008","unstructured":"Schneider M, Schoemig E, Leweke FM (2008) Acute and chronic cannabinoid treatment differentially affects recognition memory and social behavior in pubertal and adult rats. Addict Biol 13:345\u2013357","journal-title":"Addict Biol"},{"key":"26_CR59","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/sj.npp.1300770","volume":"31","author":"ME Singh","year":"2006","unstructured":"Singh ME, McGregor IS, Mallet PE (2006) Perinatal exposure to delta(9)- tetrahydrocannabinol alters heroin-induced place conditioning and fos- immunoreactivity. Neuropsychopharmacology 31:58\u201369","journal-title":"Neuropsychopharmacology"},{"key":"26_CR60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1037\/0735-7036.122.1.1","volume":"122","author":"SM Siviy","year":"2008","unstructured":"Siviy SM, Harrison KA (2008) Effects of neonatal handling on play behavior and fear towards a predator odor in juvenile rats (Rattus norvegicus). J Comp Psychol 122:1\u20138","journal-title":"J Comp Psychol"},{"key":"26_CR61","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.biopsych.2006.03.073","volume":"61","author":"MS Spano","year":"2007","unstructured":"Spano MS, Ellgren M, Wang X, Hurd YL (2007) Prenatal cannabis exposure increases heroin seeking with allostatic changes in limbic enkephalin systems in adulthood. Biol Psychiatry 61:554\u2013563","journal-title":"Biol Psychiatry"},{"key":"26_CR62","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1080\/10253890701653039","volume":"11","author":"A Stamatakis","year":"2008","unstructured":"Stamatakis A, Pondiki S, Kitraki E, Diamantopoulou A, Panagiotaropoulos T, Raftogianni A, Stylianopoulou F (2008) Effect of neonatal handling on adult rat spatial learning and memory following acute stress. Stress 11:148\u2013159","journal-title":"Stress"},{"key":"26_CR63","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s00213-008-1162-3","volume":"198","author":"V Trezza","year":"2008","unstructured":"Trezza V, Campolongo P, Cassano T, Macheda T, Dipasquale P, Carratu MR, Gaetani S, Cuomo V (2008) Effects of perinatal exposure to delta-9-tetrahydrocannabinol on the emotional reactivity of the offspring: a longitudinal behavioral study in Wistar rats. Psychopharmacology (Berl) 198:529\u2013537","journal-title":"Psychopharmacology (Berl)"},{"key":"26_CR64","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/0006-8993(95)00255-O","volume":"680","author":"G Vela","year":"1995","unstructured":"Vela G, Fuentes JA, Bonnin A, Fernandez-Ruiz J, Ruiz-Gayo M (1995) Perinatal exposure to delta 9-tetrahydrocannabinol (delta 9-THC) leads to changes in opioid- related behavioral patterns in rats. Brain Res 680:142\u2013147","journal-title":"Brain Res"},{"key":"26_CR65","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0006-8993(98)00766-5","volume":"807","author":"G Vela","year":"1998","unstructured":"Vela G, Martin S, Garcia-Gil L, Crespo JA, Ruiz-Gayo M, Fernandez-Ruiz JJ, Garcia-Lecumberri C, Pelaprat D, Fuentes JA, Ramos JA, Ambrosio E (1998) Maternal exposure to D9-tetrahydrocannabinol facilitates morphine self-administration behavior and changes regional binding to central m opioid receptors in adult offspring female rats. Brain Res 807:101\u2013109","journal-title":"Brain Res"},{"key":"26_CR66","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.tox.2008.04.019","volume":"249","author":"H Viberg","year":"2008","unstructured":"Viberg H, Ponten E, Eriksson P, Gordh T, Fredriksson A (2008) Neonatal ketamine exposure results in changes in biochemical substrates of neuronal growth and synaptogenesis, and alters adult behavior irreversibly. Toxicology 249:153\u2013159","journal-title":"Toxicology"},{"key":"26_CR67","doi-asserted-by":"crossref","first-page":"e3320","DOI":"10.1371\/journal.pone.0003320","volume":"3","author":"H Wang","year":"2008","unstructured":"Wang H, Xie H, Dey SK (2008) Loss of cannabinoid receptor CB1 induces preterm birth. PLoS ONE 3:e3320","journal-title":"PLoS ONE"},{"key":"26_CR68","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1590\/S1516-44462008000300015","volume":"30","author":"AW Zuardi","year":"2008","unstructured":"Zuardi AW (2008) Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action. Rev Bras Psiquiatr 30:271\u2013280","journal-title":"Rev Bras Psiquiatr"},{"key":"26_CR69","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1056\/NEJM198903233201203","volume":"320","author":"B Zuckerman","year":"1989","unstructured":"Zuckerman B, Frank DA, Hingson R, Amaro H, Levenson SM, Kayne H, Parker S, Vinci R, Aboagye K, Fried LE (1989) Effects of maternal marijuana and cocaine use on fetal growth. N Engl J Med 320:762\u2013768","journal-title":"N Engl J Med"}],"container-title":["European Archives of Psychiatry and Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00406-009-0026-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00406-009-0026-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00406-009-0026-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T18:20:12Z","timestamp":1559067612000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00406-009-0026-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7,2]]},"references-count":69,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["26"],"URL":"https:\/\/doi.org\/10.1007\/s00406-009-0026-0","relation":{},"ISSN":["0940-1334","1433-8491"],"issn-type":[{"value":"0940-1334","type":"print"},{"value":"1433-8491","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,7,2]]}}}