{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:18:19Z","timestamp":1791357499138,"version":"4.3.1"},"reference-count":168,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2013,8,13]],"date-time":"2013-08-13T00:00:00Z","timestamp":1376352000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Arch Psychiatry Clin Neurosci"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1007\/s00406-013-0436-x","type":"journal-article","created":{"date-parts":[[2013,8,12]],"date-time":"2013-08-12T10:40:38Z","timestamp":1376304038000},"page":"3-28","source":"Crossref","is-referenced-by-count":112,"title":["Physical comorbidity and its relevance on mortality in schizophrenia: a naturalistic 12-year follow-up in general hospital admissions"],"prefix":"10.1007","volume":"264","author":[{"given":"Dieter","family":"Schoepf","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hardeep","family":"Uppal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Potluri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reinhard","family":"Heun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,8,13]]},"reference":[{"key":"436_CR1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/ajmg.10340","volume":"115","author":"HK Ackerblom","year":"2002","unstructured":"Ackerblom HK, Vaarala O, Hyoty H et al (2002) Environmental factors in the aetiology of type 1 diabetes. Am J Med Genet 115:18\u201329","journal-title":"Am J Med Genet"},{"issue":"4","key":"436_CR2","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s11892-006-0057-0","volume":"6","author":"KG Alberti","year":"2006","unstructured":"Alberti KG, Zimmer P (2006) The metabolic syndrome: time to reflect. Curr Diab Rep 6(4):259\u2013261","journal-title":"Curr Diab Rep"},{"issue":"6","key":"436_CR3","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1177\/1062860612436576","volume":"27","author":"JS Albrecht","year":"2012","unstructured":"Albrecht JS, Hirshon JM, Goldberg R, Langenbeg P, Day HR, Morgan DJ, Comer AC, Harris AD, Furuno JP (2012) Serious mental illness and acute hospital readmission in diabetic patients. Am J Med Qual 27(6):503\u2013508","journal-title":"Am J Med Qual"},{"issue":"11","key":"436_CR4","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1111\/j.1464-5491.2006.01943.x","volume":"23","author":"S Ali","year":"2006","unstructured":"Ali S, Stone MA, Peters JL, Davies MJ, Khunti K (2006) The prevalence of co-morbid depression in adults with type 2 diabetes: a systematic review and meta-analysis. Diabet Med 23(11):1165\u20131173","journal-title":"Diabet Med"},{"key":"436_CR5","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1378\/chest.116.2.375","volume":"116","author":"J Almirall","year":"1999","unstructured":"Almirall J, Gonzales CA, Balanco X, Bolibar I (1999) Proportion of community-acquired pneumonia attributable to tobacco smoking. Chest 116:375\u2013379","journal-title":"Chest"},{"key":"436_CR6","volume-title":"Diabetes 2001: vital statistics","author":"American Diabetes Association","year":"2001","unstructured":"American Diabetes Association (2001) Diabetes 2001: vital statistics. ADA, Alexandria"},{"issue":"12","key":"436_CR7","first-page":"00189-3","volume":"S0278\u20135846","author":"G Anderson","year":"2012","unstructured":"Anderson G, Maes M, Berk M (2012) Schizophrenia is primed for an increased expression of depression through activation of immuno-inflammatory, oxidative and nitrosative stress, and tryptophan catabolite pathways. Prog Neuropsychopharmacol Biol Psychiatry S0278\u20135846(12):00189-3","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"436_CR8","author":"NP Arora","year":"2012","unstructured":"Arora NP, Ghali JK (2012) Iron deficiency anaemia in heart failure. Heart Fail Rev. doi: 10.1007\/s10741-012-9342","journal-title":"Heart Fail Rev"},{"key":"436_CR9","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0002-9149(89)90117-3","volume":"63","author":"G Assmann","year":"1989","unstructured":"Assmann G, Schulte H (1989) European lipid guidelines: therapeutic recommendations. European Atherosclerosis Society. Am J Cardiol 63:53\u201355","journal-title":"Am J Cardiol"},{"issue":"12","key":"436_CR10","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1002\/pds.1325","volume":"15","author":"P Auquier","year":"2006","unstructured":"Auquier P, Lan\u00e7on C, Rouillon F, Lader M, Holmes C (2006) Mortality in schizophrenia. Pharmacoepidemiol Drug Saf 15(12):873\u2013879","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"436_CR11","doi-asserted-by":"crossref","unstructured":"Beary M, Hodgson R, Wildgust HJ (2012) A critical review of major mortality risk factors for all cause mortality in first-episode schizophrenia: clinical and research implications. J Psychopharmacol. doi: 10.1177\/0269881112440512","DOI":"10.1177\/0269881112440512"},{"key":"436_CR12","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0920-9964(02)00315-8","volume":"61","author":"RJ Beninger","year":"2003","unstructured":"Beninger RJ, Wasserman J, Zanibbi K, Charbonneau D, Mangels J, Beninger BV (2003) Typical and atypical antipsychotic medications differentially affect two nondeclarative memory tasks in schizophrenic patients: a double dissociation. Schizophr Res 61:281\u2013292","journal-title":"Schizophr Res"},{"issue":"3","key":"436_CR13","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/j.1753-6405.2010.00532.x","volume":"34","author":"MY Bertram","year":"2010","unstructured":"Bertram MY, Vos T (2010) Quantifying the duration of pre-diabetes. Aust N Z J Public Health 34(3):311\u2013314","journal-title":"Aust N Z J Public Health"},{"key":"436_CR14","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1378\/chest.09-2702","volume":"138","author":"J Bordon","year":"2010","unstructured":"Bordon J, Wiemken T, Peyrani P, Paz ML, Gnoni M, Cabral P et al (2010) Decrease in long-term survival for hospitalized patients with community-acquired pneumonia. Chest 138:279\u2013283","journal-title":"Chest"},{"key":"436_CR15","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1007\/PL00007545","volume":"251","author":"R Bottlender","year":"2001","unstructured":"Bottlender R, Jager M, Groll C, Strauss A, Moeller HJ (2001) Deficit states in schizophrenia and their association with the length of illness and gender. Eur Arch Psychiatry Clin Neurosci 251:272\u2013278","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"436_CR16","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1034\/j.1600-0447.2000.90063.x","volume":"101","author":"R Bottlender","year":"2000","unstructured":"Bottlender R, Strauss A, Moeller HJ (2000) Prevalence and background factors of depression in first admitted schizophrenic patients. Acta Psychiatr Scand 101:153\u2013160","journal-title":"Acta Psychiatr Scand"},{"issue":"1","key":"436_CR17","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.schres.2009.12.016","volume":"117","author":"LC Bresee","year":"2010","unstructured":"Bresee LC, Majumdar SR, Patten SB, Johnson JA (2010) Prevalence of cardiovascular risk factors and disease in people with schizophrenia: a population-based study. Schizophr Res 117(1):75\u201382","journal-title":"Schizophr Res"},{"key":"436_CR18","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1192\/bjp.177.3.212","volume":"177","author":"S Brown","year":"2000","unstructured":"Brown S, Inskip H, Barraclough B (2000) Causes of the excess mortality of schizophrenia. Br J Psychiatry 177:212\u2013217","journal-title":"Br J Psychiatry"},{"key":"436_CR19","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.schres.2007.10.005","volume":"98","author":"RM Capasso","year":"2008","unstructured":"Capasso RM, Lineberry TW, Bostwick JM et al (2008) Mortality in schizophrenia and schizoaffective disorder: an Olmsted County, Minnesota cohort: 1950\u20132005. Schizophr Res 98:287\u2013294","journal-title":"Schizophr Res"},{"issue":"11","key":"436_CR20","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1111\/j.1525-1497.2006.00563.x","volume":"21","author":"CP Carney","year":"2006","unstructured":"Carney CP, Jones L, Woolson RF (2006) Medical comorbidity in women and men in schizophrenia. A population-based controlled study. J Gen Intern Med 21(11):1133\u20131137","journal-title":"J Gen Intern Med"},{"key":"436_CR21","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0168-8227(02)00200-0","volume":"59","author":"F Carral","year":"2003","unstructured":"Carral F, Olveira G, Aguilar M et al (2003) In-hospital discharge records underreport the prevalence of diabetes in hospitals. Diabetes Res Clin Pract 59:145\u2013151","journal-title":"Diabetes Res Clin Pract"},{"key":"436_CR22","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","volume":"40","author":"ME Charlson","year":"1987","unstructured":"Charlson ME, Pompei P, Ales KL, Mac Kenzie CR (1987) A new method of classifying comorbidity in longitudinal studies: development and validation. J Chron Dis 40:373\u2013383","journal-title":"J Chron Dis"},{"key":"436_CR23","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1590\/S1516-44462008005000014","volume":"30","author":"L Chaves","year":"2008","unstructured":"Chaves L, Shirakawa I (2008) Nicotine use in patients with schizophrenia evaluated by the Fagerstrom Tolerance Questionnaire: a descriptive analysis from a Brazilian sample. Rev Bras Psyquiatr 30:350\u2013352","journal-title":"Rev Bras Psyquiatr"},{"key":"436_CR24","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1093\/schbul\/sbq019","volume":"37","author":"YH Chen","year":"2011","unstructured":"Chen YH, Lin HC (2011) Poor clinical outcomes among pneumonia patients with schizophrenia. Schizophr Bull 37:1088\u20131094","journal-title":"Schizophr Bull"},{"key":"436_CR25","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.psychres.2008.07.023","volume":"178","author":"YH Chen","year":"2010","unstructured":"Chen YH, Lee HC, Lin HC (2010) Mortality among psychiatric patients in Taiwan: results from a universal National Health Insurance programme. Psychiatry Res 178:160\u2013165","journal-title":"Psychiatry Res"},{"issue":"4","key":"436_CR26","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.jpsychires.2012.12.007","volume":"47","author":"FH Chou","year":"2013","unstructured":"Chou FH, Tsai KY et al (2013) The incidence and all-cause mortality of pneumonia in patients with schizophrenia: a nine-year follow-up study. J Psychiatr Res 47(4):460\u2013466","journal-title":"J Psychiatr Res"},{"key":"436_CR27","doi-asserted-by":"crossref","unstructured":"Chwastiak L, Rosenheck RA, McEvoy JP, Keefe RS, Swartz MS, Lieberman MD (2006) Interrelationships of psychiatric symptom severity, medical comorbidity, and functioning in Schizophrenia. Psychiatr Serv 57(8):1102\u20131109, ps.psychiatryonline.org","DOI":"10.1176\/appi.ps.57.8.1102"},{"issue":"1","key":"436_CR28","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3928\/00485713-20050101-09","volume":"35","author":"D Cimpean","year":"2005","unstructured":"Cimpean D, Torrey WC, Green AI (2005) Schizophrenia and co-occurring general medical illness. Psychiatr Ann 35(1):71\u201381","journal-title":"Psychiatr Ann"},{"issue":"7","key":"436_CR29","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1097\/01.smj.0000167621.49292.11","volume":"98","author":"L Citrome","year":"2005","unstructured":"Citrome L, Blonde L, Damatarca C (2005) Metabolic issues in patients with severe mental illness. South Med J 98(7):715\u2013720","journal-title":"South Med J"},{"key":"436_CR30","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1176\/appi.ps.55.9.1006","volume":"55","author":"L Citrome","year":"2004","unstructured":"Citrome L, Jaffe A, Levine J, Allingham B, Robinson J (2004) Relationship between antipsychotic treatment and new cases of diabetes among psychiatric inpatients. Psychiatr Serv 55:1006\u20131013","journal-title":"Psychiatr Serv"},{"issue":"10","key":"436_CR31","doi-asserted-by":"crossref","first-page":"777","DOI":"10.26719\/2011.17.10.777","volume":"17","author":"T Coclami","year":"2011","unstructured":"Coclami T, Cross M (2011) Psychiatric comorbidity with type 1 and type 2 diabetes mellitus. East Mediterr Health J 17(10):777\u2013783","journal-title":"East Mediterr Health J"},{"key":"436_CR32","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/00019442-200002000-00003","volume":"8","author":"CI Cohen","year":"2000","unstructured":"Cohen CI, Cohen GD, Blank K, Gaitz C, Katz IR, Leuchter A, Maletta G, Meyers B, Sakauye K, Shamoian C (2000) Schizophrenia and older adults: an overview\u2014directions for research and policy. Am J Geriat Psychiatry 8:19\u201328","journal-title":"Am J Geriat Psychiatry"},{"key":"436_CR33","unstructured":"Cooper JE (1994) Pocket guide to the ICD-10 classification of mental and behavioral disorders, with Glossary and Diagnostic Criteria for research. Churchill Livingstone 1994 (Edinburgh, London, Melbourne, New York and Tokyo), in behalf of WHO"},{"key":"436_CR34","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.pnpbp.2007.01.008","volume":"31","author":"LA Copeland","year":"2007","unstructured":"Copeland LA, Mortensen EM, Zeber JE, Pugh MJ, Restrepo MI, Dalack GW (2007) Pulmonary disease among inpatients decedents: impact of schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 31:720\u2013727","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"436_CR35","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1161\/CIRCULATIONAHA.111.040766","volume":"125","author":"VF Corrales-Medina","year":"2012","unstructured":"Corrales-Medina VF, Musher DM, Wells GA, Chirinos JA, Chen L, Fine MJ (2012) Cardiac complications in patients with community-acquired pneumonia: incidence, timing, risk factors, and association with short-term mortality. Circulation 125:773\u2013781","journal-title":"Circulation"},{"issue":"6","key":"436_CR36","first-page":"27","volume":"66","author":"F Cournos","year":"2005","unstructured":"Cournos F, McKinnon K, Sullivan G (2005) Schizophrenia and comorbid human immunodeficiency virus or hepatitis C virus. J Clin Psychiatry 66(6):27\u201333","journal-title":"J Clin Psychiatry"},{"issue":"4","key":"436_CR37","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/0010-440X(90)90042-Q","volume":"31","author":"LS Covey","year":"1990","unstructured":"Covey LS, Glassman AH, Stetner F (1990) Depression and depressive symptoms in smoking cessation. Compr Psychiatry 31(4):350\u2013354","journal-title":"Compr Psychiatry"},{"issue":"3","key":"436_CR38","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1176\/appi.ajp.2012.12050599","volume":"170","author":"C Crump","year":"2013","unstructured":"Crump C, Winkleby MA, Sundquist K, Sundquist J (2013) Comorbidities and mortality in persons with schizophrenia: a Swedish national cohort study. Am J Psychiatry 170(3):324\u2013333","journal-title":"Am J Psychiatry"},{"key":"436_CR39","doi-asserted-by":"crossref","first-page":"715","DOI":"10.4088\/JCP.v65n0519","volume":"65","author":"AM Curkendall","year":"2004","unstructured":"Curkendall AM, Jingping M, Glasser DB, Stang MR, Jones JK (2004) Cardiovascular disease in patients with schizophrenia in Saskatchewan, Canada. J Clin Psychiatry 65:715\u2013720","journal-title":"J Clin Psychiatry"},{"key":"436_CR40","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1002\/dme.1996.13.s6.148","volume":"13","author":"CJ Currie","year":"1996","unstructured":"Currie CJ, Williams DRR, Peters JR (1996) Pattern\u2019s for in and out patient activity for diabetes: a district survey. Diabetic Med 13:148\u2013153","journal-title":"Diabetic Med"},{"key":"436_CR41","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1001\/archpsyc.63.3.267","volume":"63","author":"GL Daumit","year":"2006","unstructured":"Daumit GL, Pronovost PJ, Anthony CB, Guallar E, Steinwachs DM, Ford DE (2006) Adverse events during medical and surgical hospitalisations for patients with schizophrenia. Arch Gen Psychiatry 63:267\u2013272","journal-title":"Arch Gen Psychiatry"},{"key":"436_CR42","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.psychres.2009.01.006","volume":"176","author":"GL Daumit","year":"2010","unstructured":"Daumit GL, Anthony CB, Ford DE et al (2010) Pattern of mortality in a sample of Maryland residents with severe mental illness. Psychiatry Res 176:242\u2013245","journal-title":"Psychiatry Res"},{"key":"436_CR43","first-page":"1591","volume-title":"Comprehensive textbook of psychiatry","author":"JM Davis","year":"1989","unstructured":"Davis JM, Barter JT, Kane JM (1989) Antipsychotic drugs. In: Kaplan HI, Sadock BJ (eds) Comprehensive textbook of psychiatry, 5th edn. Williams & Wilkins, Baltimore, pp 1591\u20131626","edition":"5"},{"issue":"2\u20133","key":"436_CR44","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.schres.2005.02.010","volume":"76","author":"J Leon De","year":"2005","unstructured":"De Leon J, Diaz FJ (2005) A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors. Schizophr Res 76(2\u20133):135\u2013157","journal-title":"Schizophr Res"},{"key":"436_CR45","first-page":"433","volume":"152","author":"J Leon De","year":"1995","unstructured":"De Leon J, Dadvand M, Canuso C, White AO, Stanilla JK, Simpson GM (1995) Schizophrenia and smoking: an epidemiological survey in a state hospital. Am J Psychiatry 152:433\u2013455","journal-title":"Am J Psychiatry"},{"issue":"19","key":"436_CR46","first-page":"2388","volume":"29","author":"K Dickstein","year":"2009","unstructured":"Dickstein K, Cohen Solal A et al (2009) ESC Guidelines fort the diagnosis and treatment of acute and chronic heart failure: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Eur Heart J 29(19):2388\u20132442","journal-title":"Eur Heart J"},{"key":"436_CR47","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1001\/jama.283.4.506","volume":"283","author":"BG Druss","year":"2000","unstructured":"Druss BG, Bradford DW, Rosenheck RA, Radford MU, Krumholz HM (2000) Mental disorders and use of cardiovascular procedures after myocardial infarction. JAMA 283:506\u2013511","journal-title":"JAMA"},{"key":"436_CR48","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1001\/archpsyc.58.6.565","volume":"58","author":"BG Druss","year":"2001","unstructured":"Druss BG, Bradford WD, Roseneck RA, Radford MJ, Krumholz HM (2001) Quality of medical care and access mortality in older patients with mental disorders. Arch Gen Psychiatry 58:565\u2013572","journal-title":"Arch Gen Psychiatry"},{"key":"436_CR49","unstructured":"Druss BG, Reisinger-Walker E (2011) Mental disorders and medical comorbidity. Robert Wood Johnson Foundation, Princeton. Retrieved from http:\/\/www.rwjf.org\/files\/research\/71883.mentalhealth.report.pdf"},{"issue":"11","key":"436_CR50","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1017\/S0033291709990316","volume":"39","author":"A Dutt","year":"2009","unstructured":"Dutt A, McDonald C, Dempster E, Prata D, Shaikh M, Williams I et al (2009) The effect of COMT, BDNF, 5-HTT, NRG1 and DTNBP1 genes on hippocampal and lateral ventricular volume in psychosis. Psychol Med 39(11):1783\u20131797","journal-title":"Psychol Med"},{"key":"436_CR51","doi-asserted-by":"crossref","unstructured":"Egede LE (2007) Major depression in individuals with chronic medical disorders. Prevalence, correlates and association with health resource utilization. Lost Productivity and functional disability. Gen Hosp Psychiatry 29(5):409\u2013416","DOI":"10.1016\/j.genhosppsych.2007.06.002"},{"key":"436_CR52","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.apnu.2005.09.002","volume":"20","author":"P El-Mallah","year":"2006","unstructured":"El-Mallah P (2006) Evolving self-care in individuals with schizophrenia and diabetes mellitus. Arch Psychiatr Nurs 20:55\u201364","journal-title":"Arch Psychiatr Nurs"},{"key":"436_CR53","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1080\/08039480701414932","volume":"61","author":"BM Fors","year":"2007","unstructured":"Fors BM, Isacson D, Bingefors K, Widerlow B (2007) Mortality among persons with schizophrenia in Sweden: an epidemiological study. Nord J Psychiatry 61:252\u2013259","journal-title":"Nord J Psychiatry"},{"key":"436_CR54","doi-asserted-by":"crossref","unstructured":"Fusar-Poli P, Borgwardt S, Bechdolf A et al (2012). The psychosis high risk state. A comprehensive state-of-the-art review. Arch Gen Psychiatry. doi: 10.1001\/jamapsychiatry.2013.269","DOI":"10.1001\/jamapsychiatry.2013.269"},{"issue":"4676","key":"436_CR55","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1126\/science.6387913","volume":"226","author":"AH Glassman","year":"1984","unstructured":"Glassman AH, Jackson WK, Walsh BT, Roose SP, Rosenfeld B (1984) Cigarette craving, smoking withdrawal, and clonidine. Science 226(4676):864\u2013866","journal-title":"Science"},{"issue":"19","key":"436_CR56","doi-asserted-by":"crossref","first-page":"2863","DOI":"10.1001\/jama.1988.03720190031026","volume":"259","author":"AH Glassman","year":"1988","unstructured":"Glassman AH, Stetner F, Walsh BT, Raizman PS, Fleiss JL, Cooper TB, Covey LS (1988) Heavy smokers, smoking cessation, and clonidine. Results of a double-blind, randomized trial. JAMA 259(19):2863\u20132866","journal-title":"JAMA"},{"issue":"1","key":"436_CR57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2165\/00003495-199040010-00001","volume":"40","author":"AH Glassman","year":"1990","unstructured":"Glassman AH, Covey LS (1990) Future trends in the pharmacological treatment of smoking cessation. Drugs 40(1):1\u20135","journal-title":"Drugs"},{"issue":"12","key":"436_CR58","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1001\/jama.1990.03450120058029","volume":"264","author":"AH Glassman","year":"1990","unstructured":"Glassman AH, Helzer JE, Covey LS, Cottler LB, Stetner F, Tipp JE, Johnson J (1990) Smoking, smoking cessation, and major depression. JAMA 264(12):1546\u20131549","journal-title":"JAMA"},{"key":"436_CR59","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1177\/070674370204700904","volume":"47","author":"EM Goldner","year":"2002","unstructured":"Goldner EM, Hsu L, Waraich P, Somers JM (2002) Prevalence and incidence studies of schizophrenic disorders: a systematic review of the literature. Can J Psychiatry 47:833\u2013843","journal-title":"Can J Psychiatry"},{"key":"436_CR60","doi-asserted-by":"crossref","first-page":"129","DOI":"10.2174\/1568007024606230","volume":"1","author":"AI Green","year":"2002","unstructured":"Green AI, Salomon MS, Brenner MJ, Rawlins K (2002) Treatment of schizophrenia and comorbid substance use disorder. Curr Drug Targest CNS Neurol Disord 1:129\u2013139","journal-title":"Curr Drug Targest CNS Neurol Disord"},{"key":"436_CR61","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1136\/bmj.1.6174.1332","volume":"1","author":"LM George","year":"1979","unstructured":"George LM, Maddock K (1979) Accuracy of in-hospital activity notifications for infectious diseases. Br Med J 1:1332\u20131339","journal-title":"Br Med J"},{"key":"436_CR62","doi-asserted-by":"crossref","unstructured":"Ghali JK (2009) Anaemia and heart failure. Curr Opin Cardiol. doi: 10.1097\/HCO.0b013e328324ecec","DOI":"10.1097\/HCO.0b013e328324ecec"},{"key":"436_CR63","doi-asserted-by":"crossref","first-page":"183","DOI":"10.4088\/JCP.v66n0205","volume":"66","author":"DC Goff","year":"2005","unstructured":"Goff DC, Cather C, Evins AE et al (2005) Medical morbidity and mortality in schizophrenia: guideline for psychiatrist. J Clin Psychiatry 66:183\u2013194","journal-title":"J Clin Psychiatry"},{"key":"436_CR64","doi-asserted-by":"crossref","unstructured":"Guh DP, Zhang W, Bansback N, Amarsi Z, Birmingham CL, Anis AH (2009) The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis. BMC Public Health. doi: 10.1186\/1471-2458-9-88","DOI":"10.1186\/1471-2458-9-88"},{"key":"436_CR65","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1177\/070674379704200204","volume":"42","author":"H Hafner","year":"1997","unstructured":"Hafner H, an der Heiden W (1997) Epidemiology of schizophrenia. Can J Psychiatry 42:139\u2013151","journal-title":"Can J Psychiatry"},{"key":"436_CR66","doi-asserted-by":"crossref","first-page":"2474","DOI":"10.1001\/archinte.168.22.2474","volume":"168","author":"M Hamer","year":"2008","unstructured":"Hamer M, Stamatakis E, Steptoe A (2008) Psychiatric hospital admissions, behavioural risk factors, and all cause mortality the Scottish health survey. Arch Intern Med 168:2474\u20132479","journal-title":"Arch Intern Med"},{"issue":"1","key":"436_CR67","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.eurpsy.2011.06.001","volume":"28","author":"R Heun","year":"2013","unstructured":"Heun R, Schoepf D, Potluri R, Natalwala A (2013) Alzheimer\u2019s disease and co-morbidity: increased prevalence and possible risk factors of excess mortality in a naturalistic 7-year follow-up. Eur Psychiatry 28(1):40\u201348","journal-title":"Eur Psychiatry"},{"key":"436_CR68","first-page":"295","volume":"58","author":"A Hill","year":"1965","unstructured":"Hill A (1965) The environment and disease: association or causation. Proc R Soc Med 58:295\u2013330","journal-title":"Proc R Soc Med"},{"key":"436_CR69","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1176\/appi.ajp.161.12.2317","volume":"161","author":"S Himmelhoch","year":"2004","unstructured":"Himmelhoch S, Lehman A, Kreyenbuhl J, Daumit G, Brown C, Dixon L (2004) Prevalence of chronic obstructive pulmonary disease among those with serious mental illness. Am J Psychiatry 161:2317\u20132319","journal-title":"Am J Psychiatry"},{"key":"436_CR70","doi-asserted-by":"crossref","unstructured":"Hoang U, Stewart R, Goldacre MJ (2011) Mortality after hospital discharge for people with schizophrenia or bipolar disorder: retrospective study of linked English hospital episode statistics. BMJ. doi: 10.1136\/bmj.d5422","DOI":"10.1136\/bmj.d5422"},{"issue":"4 suppl","key":"436_CR71","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1177\/1359786810385489","volume":"24","author":"R Hodgson","year":"2010","unstructured":"Hodgson R, Wildgust HJ, Bushe CJ (2010) Review: cancer and schizophrenia\u2014is there a paradox? J Psychopharmacol 24(4 suppl):51\u201360. doi: 10.1177\/1359786810385489","journal-title":"J Psychopharmacol"},{"key":"436_CR72","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1192\/bjp.184.47.s55","volume":"184","author":"RIG Holt","year":"2004","unstructured":"Holt RIG (2004) Diagnosis, epidemiology and pathogenesis of diabetes mellitus: an update for psychiatrists. Br J Psychiatry 184:55\u201363","journal-title":"Br J Psychiatry"},{"key":"436_CR73","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0920-9964(00)00064-5","volume":"47","author":"J Hooley","year":"2001","unstructured":"Hooley J, Delgado M (2001) Pain insensitivity in the relatives of schizophrenia patients. Schizophr Res 47:265\u2013267","journal-title":"Schizophr Res"},{"issue":"4","key":"436_CR74","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1177\/1359786810385490","volume":"24","author":"K Hor","year":"2010","unstructured":"Hor K, Taylor M (2010) Suicide and schizophrenia: a systematic review of rates and risk factors. J Psychopharmacol 24(4):81\u201390","journal-title":"J Psychopharmacol"},{"key":"436_CR75","unstructured":"International Diabetes Federation (2003) Diabetes Atlas. Retrieved from http:\/\/www.idf.org\/sites\/default\/files\/IDF_Diabetes_Atlas_2ndEd.pdf"},{"key":"436_CR76","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1192\/bjp.187.3.243","volume":"187","author":"H Ito","year":"2005","unstructured":"Ito H, Koyama A, Higuchi T (2005) Polypharmacy and excessive dosing: psychiatrist\u2019s perceptions of antipsychotic drug prescription. Br J Psychiatry 187:243\u2013247","journal-title":"Br J Psychiatry"},{"key":"436_CR77","doi-asserted-by":"crossref","unstructured":"Howes O, Ohlson R, Pilowsky LS (2003) Effect of clozapine on mortality. Br J Psychiatry 183:460\u2013461. doi: 10.1192\/bjp.183.5.460","DOI":"10.1192\/bjp.183.5.460"},{"key":"436_CR78","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0920-9964(97)85354-6","volume":"28","author":"A Jablensky","year":"1997","unstructured":"Jablensky A (1997) The 100-year epidemiology of schizophrenia. Schizophr Res 28:111\u2013125","journal-title":"Schizophr Res"},{"issue":"2","key":"436_CR79","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.amjmed.2008.07.027","volume":"122","author":"A Jeremias","year":"2009","unstructured":"Jeremias A, Kaul S et al (2009) The impact of revascularisation on mortality in patients with non-acute coronary artery disease. Am J Med 122(2):151\u2013161","journal-title":"Am J Med"},{"issue":"8","key":"436_CR80","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1007\/s00125-009-1380-1","volume":"52","author":"G Joshy","year":"2009","unstructured":"Joshy G, Dunn P, Fisher M, Lawrenson R (2009) Ethnic differences in the natural progression of nephropathy among diabetes patients in New Zealand: hospital admission rate for renal complications, and incidence of end-stage renal disease and renal death. Diabetologia 52(8):1474\u20131478","journal-title":"Diabetologia"},{"issue":"10","key":"436_CR81","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1093\/qjmed\/hcm080","volume":"100","author":"N Joss","year":"2007","unstructured":"Joss N, Patel R, Paterson K, Simpson K, Perry C, Stirling C (2007) Anaemia is common and predicts mortality in diabetic nephropathy. QJM 100(10):641\u2013647","journal-title":"QJM"},{"issue":"4","key":"436_CR82","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.cardfail.2008.11.006","volume":"15","author":"M Kamalesh","year":"2009","unstructured":"Kamalesh M, Cleophas TJ (2009) Heart failure due to systolic dysfunction and mortality in diabetes: pooled analysis of 39,505 subjects. J Card Fail 15(4):305\u2013309","journal-title":"J Card Fail"},{"issue":"4","key":"436_CR83","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1093\/schbul\/sbp152","volume":"37","author":"DL Kelly","year":"2009","unstructured":"Kelly DL, Mahon RP, Wehring HJ, Liu F et al (2009) Cigarette smoking and mortality risk in people with schizophrenia. Schizophr Bull 37(4):832\u2013838","journal-title":"Schizophr Bull"},{"issue":"1","key":"436_CR84","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1037\/h0080151","volume":"66","author":"RC Kessler","year":"1996","unstructured":"Kessler RC, Nelson CB, McGonagle KA, Edlund MJ, Frank RG, Leaf PJ (1996) The epidemiology of co-occurring addictive and mental disorders: implications for prevention and service utilization. Am J Orthopsychiatry 66(1):17\u201331","journal-title":"Am J Orthopsychiatry"},{"key":"436_CR85","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.genhosppsych.2009.07.008","volume":"31","author":"A Kilbourne","year":"2009","unstructured":"Kilbourne A, Morden N, Austin K, IIgen M, McCarthy J, Dallack G (2009) Excess heart disease-related mortality in a national study of patients with mental disorders: identifying modifiable risk factors. Gen Hosp Psychiatry 31:555\u2013563","journal-title":"Gen Hosp Psychiatry"},{"key":"436_CR86","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1016\/S0140-6736(99)10385-4","volume":"354","author":"JG Killian","year":"1999","unstructured":"Killian JG, Kerr K, Lawrence C, Celermajer DS (1999) Myocarditis and cardiomyopathy associated with clozapine. Lancet 354:1841\u20131845","journal-title":"Lancet"},{"issue":"5","key":"436_CR87","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1007\/s00125-006-0159-x","volume":"49","author":"MJ Knol","year":"2006","unstructured":"Knol MJ, Twisk JW, Beekman AT, Heine RJ, Snoek FJ, Pouwer F (2006) Depression as a risk factor for the onset of type 2 diabetes mellitus: a meta-analysis. Diabetologia 49(5):837\u2013845","journal-title":"Diabetologia"},{"key":"436_CR88","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1001\/archinte.159.14.1550","volume":"159","author":"I Koivula","year":"1999","unstructured":"Koivula I, Sten M, Makela PH (1999) Prognosis after community-acquired pneumonia in the elderly: a population based 12-year follow-up study. Arch Intern Med 159:1550\u20131555","journal-title":"Arch Intern Med"},{"key":"436_CR89","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.2337\/dc06-2417","volume":"30","author":"JB Kornum","year":"2007","unstructured":"Kornum JB, Thomson RW, Riis A et al (2007) Type 2 diabetes and pneumonia outcomes: a population-based cohort study. Diabetes Care 30:2251\u20132257","journal-title":"Diabetes Care"},{"key":"436_CR90","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/S0002-9343(02)01498-5","volume":"114","author":"M Kosborod","year":"2003","unstructured":"Kosborod M, Smith GL, Radford MJ, Foody JM, Krumholz HM (2003) The prognostic importance of anaemia in patients with heart failure. Am J Med 114:112\u2013119","journal-title":"Am J Med"},{"key":"436_CR91","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1097\/01.nmd.0000221177.51089.7d","volume":"194","author":"J Kreyenbuhl","year":"2006","unstructured":"Kreyenbuhl J, Dickerson FB, Medoff DR et al (2006) Extent and management of cardiovascular risk factors in patients with type 2 diabetes mellitus and serious mental illness. J Nerv Ment Dis 194:404\u2013410","journal-title":"J Nerv Ment Dis"},{"issue":"2","key":"436_CR92","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s10654-009-9405-0","volume":"25","author":"MA Laaksonen","year":"2010","unstructured":"Laaksonen MA, Knekt P, Rissanen H, H\u00e4rk\u00e4nen T, Virtala E, Marniemi J, Aromaa A, Heli\u00f6vaara M, Reunanen A (2010) The relative importance of modifiable potential risk factors of type 2 diabetes: a meta-analysis of two cohorts. Eur J Epidemiol 25(2):115\u2013124","journal-title":"Eur J Epidemiol"},{"issue":"9","key":"436_CR93","first-page":"67","volume":"178","author":"TJR Lambert","year":"2003","unstructured":"Lambert TJR, Velakoulis D, Pantellis C (2003) Medical comorbidity in schizophrenia. Med J Aus 178(9):67\u201370","journal-title":"Med J Aus"},{"key":"436_CR94","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.schres.2011.06.008","volume":"131","author":"TM Laursen","year":"2011","unstructured":"Laursen TM (2011) Life expectancy among persons with schizophrenia or bipolar affective disorder. Schizophr Res 131:101\u2013104","journal-title":"Schizophr Res"},{"key":"436_CR95","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/YCO.0b013e32835035ca","volume":"25","author":"TM Laursen","year":"2012","unstructured":"Laursen TM, Munk-Olsen T, Vestergaard M (2012) Life expectancy and cardiovascular mortality in persons with schizophrenia. Curr Opin Psychiatry 25:83\u201388","journal-title":"Curr Opin Psychiatry"},{"key":"436_CR96","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.jacc.2004.04.047","volume":"44","author":"PC Lee","year":"2004","unstructured":"Lee PC, Annapoorna SK, Ahsan C, Fisher E, Sharma SK (2004) Anaemia is an independent predictor of mortality after percutaneous coronary intervention. J Am Coll Cardiol 44:541\u2013546","journal-title":"J Am Coll Cardiol"},{"key":"436_CR97","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.1600-0447.2007.01095.x","volume":"116","author":"S Leucht","year":"2007","unstructured":"Leucht S, Burkard T, Henderson J, Maj M, Sartorius N (2007) Physical illness and schizophrenia: a review of the literature. Acta Psychiatr Scand 116:317\u2013333","journal-title":"Acta Psychiatr Scand"},{"key":"436_CR98","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1038\/sj.npp.1300157","volume":"28","author":"JA Lieberman","year":"2003","unstructured":"Lieberman JA, Phillips M, Gu H et al (2003) Atypical and conventional antipsychotic drugs in treatment-naive-first-episode schizophrenia: a 52-week randomized trail of clozapine vs chlorpromazine. Neuropsychopharmacology 28:995\u20131003. doi: 10.1038\/sj.npp.1300157","journal-title":"Neuropsychopharmacology"},{"issue":"2\u20133","key":"436_CR99","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.schres.2010.08.022","volume":"123","author":"PI Lin","year":"2010","unstructured":"Lin PI, Shuldner AR (2010) Rethinking the genetic basis for comorbidity of schizophrenia and type-2 diabetes. Schizophr Res 123(2\u20133):234\u2013243","journal-title":"Schizophr Res"},{"issue":"3","key":"436_CR100","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.ahj.2004.08.039","volume":"149","author":"J Lindenfeld","year":"2005","unstructured":"Lindenfeld J (2005) Prevalence of anaemia and effects on mortality with heart failure. Am Heart J 149(3):391\u2013401","journal-title":"Am Heart J"},{"key":"436_CR101","doi-asserted-by":"crossref","unstructured":"Liu Y, Zezhi L, Zhang M, Deng Y, Yi Z, Shi T (2013) Exploring the pathogenetic association between schizophrenia and type-2 diabetes mellitus diseases based on pathway analysis. BMC Medical Genomics 6(Suppl 1):S17. Retrieved from http:\/\/www.biomedcentral.com\/1755-8794\/6\/S1\/S17","DOI":"10.1186\/1755-8794-6-S1-S17"},{"key":"436_CR102","first-page":"221","volume":"112","author":"T Makikyro","year":"1998","unstructured":"Makikyro T, Karvonen JT, Hakko H et al (1998) Co-morbidity of hospital-treated psychiatric and physical disorders with special reference of schizophrenia: a 28\u00a0year follow-up of the 1996 northern Finland general population birth cohort. Public health 112:221\u2013228","journal-title":"Public health"},{"issue":"7","key":"436_CR103","doi-asserted-by":"crossref","first-page":"936","DOI":"10.4088\/JCP.10m06244gry","volume":"72","author":"P Manu","year":"2011","unstructured":"Manu P, Kane JM, Corell CU (2011) Sudden deaths in psychiatric patients. J Clin Psychiatry 72(7):936\u2013941","journal-title":"J Clin Psychiatry"},{"key":"436_CR104","first-page":"309","volume-title":"Textbook of psychopharmacology","author":"SR Marder","year":"1998","unstructured":"Marder SR (1998) Antipsychotic medications. In: Schatzberg AF, Nemeroff CB (eds) Textbook of psychopharmacology, 2nd edn. American Psychiatric Press, Washington, pp 309\u2013321. doi: 10.1176\/appi.books.9780890423363.45859","edition":"2"},{"key":"436_CR105","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1212\/WNL.0b013e3181eee25f","volume":"75","author":"T Matsuzaki","year":"2010","unstructured":"Matsuzaki T, Sasaki K, Tanizaki Y et al (2010) Insulin resistance is associated with the pathology of Alzheimer disease. Neurology 75:764\u2013770","journal-title":"Neurology"},{"issue":"4","key":"436_CR106","doi-asserted-by":"crossref","first-page":"810","DOI":"10.2337\/diacare.28.4.810","volume":"28","author":"FA McAlister","year":"2005","unstructured":"McAlister FA, Majumdar SR, Blitz S, Rowe BH, Romney J, Marrie TJ (2005) The relation between hyperglycaemia and outcomes in 2,471 patients admitted to the hospital with community-acquired pneumonia. Diabetes Care 28(4):810\u2013815","journal-title":"Diabetes Care"},{"key":"436_CR107","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1161\/01.CIR.0000134964.01697.C7","volume":"110","author":"RS McKechnie","year":"2004","unstructured":"McKechnie RS, Smith D, Montoye C, Kline-Rogers E, O\u2019Donnel MJ, DeFranco AC et al (2004) Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2). Prognostic implication of anaemia on in-hospital outcomes after percutaneous coronary interventions. Circulation 110:271\u2013277. doi: 10.1161\/01.CIR.0000134964.01697.C7","journal-title":"Circulation"},{"issue":"3","key":"436_CR108","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1586\/14779072.6.3.323","volume":"6","author":"SH Meeuwisse-Pasterkamp","year":"2008","unstructured":"Meeuwisse-Pasterkamp SH, van der Klauw MM, Wolffenbuttel BH (2008) Type 2 diabetes mellitus: prevention of macrovascular complications. Expert Rev Cardiovasc Ther 6(3):323\u2013341","journal-title":"Expert Rev Cardiovasc Ther"},{"issue":"7","key":"436_CR109","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1097\/01.ALC.0000171488.63823.09","volume":"29","author":"DJ Meyerhoff","year":"2005","unstructured":"Meyerhoff DJ, Bode C, Nixon SJ, de Bruin EA, Bode JC, Seitz HK (2005) Health risks of chronic moderate and heavy alcohol consumption: how much is too much? Alcohol Clin Exp Res 29(7):1334\u20131340","journal-title":"Alcohol Clin Exp Res"},{"issue":"12","key":"436_CR110","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.2337\/dc08-0985","volume":"31","author":"B Mezuk","year":"2008","unstructured":"Mezuk B, Eaton WW, Albrecht S, Golden SH (2008) Depression and type 2 diabetes over the lifespan: a meta-analysis. Diabetes Care 31(12):2383\u20132390","journal-title":"Diabetes Care"},{"key":"436_CR111","doi-asserted-by":"crossref","first-page":"D5652","DOI":"10.1136\/bmj.d5652","volume":"343","author":"BJ Miller","year":"2011","unstructured":"Miller BJ (2011) Hospital admission for schizophrenia and bipolar disorder: a critical window to recognize and modify the risk of mortality. BMJ 343:D5652","journal-title":"BMJ"},{"issue":"11 (Suppl 4)","key":"436_CR112","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/1359786810382059","volume":"24","author":"AJ Mitchell","year":"2010","unstructured":"Mitchell AJ, Dinan TJ (2010) Schizophrenia: a multisystem disease. J Psychopharmacol 24(11 (Suppl 4)):5\u20137","journal-title":"J Psychopharmacol"},{"key":"436_CR113","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1001\/archinte.162.9.1059","volume":"162","author":"EM Mortensen","year":"2002","unstructured":"Mortensen EM, Coley CM, Singer DE et al (2002) Causes of death for patients with community-acquired pneumonia: results from the Pneumonia Patient Outcomes Research Team cohort study. Arch Intern Med 162:1059\u20131064","journal-title":"Arch Intern Med"},{"key":"436_CR114","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1192\/apt.6.3.169","volume":"6","author":"C Mulholland","year":"2000","unstructured":"Mulholland C, Cooper S (2000) The symptom of depression in schizophrenia and its management. Adv Psychiatr Treat 6:169\u2013177. doi: 10.1192\/apt.6.3.169","journal-title":"Adv Psychiatr Treat"},{"key":"436_CR115","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/S0010-440X(96)90054-1","volume":"37","author":"S Mukherjee","year":"1996","unstructured":"Mukherjee S, Decina P, Bocola V, Saraceni F, Scapicchio PL (1996) Diabetes mellitus in schizophrenic patients. Compr Psychiatry 37:68\u201373","journal-title":"Compr Psychiatry"},{"key":"436_CR116","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0006-3223(97)00031-0","volume":"43","author":"GM Murphy","year":"1998","unstructured":"Murphy GM, Lim KO, Wienecke M et al (1998) No neuropathology evidence for an increased frequency of Alzheimer\u2019s disease among elderly schizophrenics. Biol Psychiatry 43:205\u2013209","journal-title":"Biol Psychiatry"},{"key":"436_CR117","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/S0140-6736(07)61415-9","volume":"370","author":"S Moussavi","year":"2007","unstructured":"Moussavi S, Chatterji S et al (2007) Depression, chronic diseases, and decrements in health: results from the World Health Surveys. Lancet 370:851\u2013858","journal-title":"Lancet"},{"key":"436_CR118","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1016\/j.jacc.2006.08.034","volume":"48","author":"JN Nanas","year":"2006","unstructured":"Nanas JN, Matsouka C, Karageorgopoulolos D, Leonti A, Tsolakis E, Drakos SG et al (2006) Aetiology of anaemia in patients with advanced heart failure. J Am Coll Cardiol 48:2485\u20132489","journal-title":"J Am Coll Cardiol"},{"key":"436_CR119","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1177\/070674379103600401","volume":"36","author":"SC Newman","year":"1991","unstructured":"Newman SC, Bland RC (1991) Mortality in a cohort of patients with schizophrenia: a record linkage study. Can J Psychiatry 36:239\u2013245","journal-title":"Can J Psychiatry"},{"issue":"23","key":"436_CR120","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.1093\/eurheartj\/ehl338","volume":"27","author":"A Nicholson","year":"2006","unstructured":"Nicholson A, Kuper H, Hemingway H (2006) Depression as an etiologic and prognostic factor in coronary heart disease: a meta-analysis of 6,362 events among 146538 participants in 54 observational studies. Eur Heart J 27(23):2763\u20132774","journal-title":"Eur Heart J"},{"key":"436_CR121","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.amjcard.2004.06.058","volume":"94","author":"E Nikolsky","year":"2004","unstructured":"Nikolsky E, Mehran R, Aymong E, Mintz GS, Lansky AJ, Lasic Z et al (2004) The impact of anaemia on outcomes of patients undergoing percutaneous coronary intervention. Am J Cardiol 94:1023\u20131027. doi: 10.1161\/CIRCINTERVENTIONS.111.965749","journal-title":"Am J Cardiol"},{"key":"436_CR122","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1097\/JCP.0b013e3181f14098","volume":"5","author":"D Novick","year":"2010","unstructured":"Novick D, Haro JM, Bertsch J, Haddad PM (2010) Incidence of extrapyramidal symptoms and tardive dyskinesia in schizophrenia: thirty-six-month results from the European schizophrenia outpatient health outcomes study. J Clin Psychopharmacol 5:531\u2013540","journal-title":"J Clin Psychopharmacol"},{"key":"436_CR123","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.1523\/JNEUROSCI.4575-09.2010","volume":"30","author":"V Oertel","year":"2010","unstructured":"Oertel V, Kn\u00f6chel C, Rotarska-Jagiela A, Schonmeyer R, Lindner M, van de Ven V, Haenschel C, Uhlhaas P, Maurer K, Linden DE (2010) Reduced laterality as a trait marker of schizophrenia: evidence from structural and functional neuroimaging. J Neurosci 30:2289\u20132299","journal-title":"J Neurosci"},{"key":"436_CR124","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1136\/bmj.321.7259.483","volume":"321","author":"U Osby","year":"2000","unstructured":"Osby U, Correia N, Brandt L et al (2000) Time trends in schizophrenia mortality in Stockholm County, Sweden. BMJ 321:483\u2013484","journal-title":"BMJ"},{"key":"436_CR125","unstructured":"Parks J, Svendsen D, Singer P, Foti ME (2006) Morbidity and mortality in people with serious mental illness. National Association of State Mental Health Program Directors (NASMHPD) Medical Directors Council, Alexandria. Retrieved from http:\/\/www.dsamh.utah.gov\/docs\/mortality-morbidity_nasmhpd.pdf"},{"issue":"3","key":"436_CR126","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1159\/000107084","volume":"24","author":"TK Phung","year":"2007","unstructured":"Phung TK, Andersen BB, H\u00f8gh P, Kessing LV, Mortensen PB, Waldemar G (2007) Validity of dementia diagnoses in the Danish in-hospital registers. Dement Geriat Cogn Disord 24(3):220\u2013228","journal-title":"Dement Geriat Cogn Disord"},{"key":"436_CR127","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1093\/schbul\/19.4.805","volume":"19","author":"I Prohovnik","year":"1993","unstructured":"Prohovnik I, Dwork AJ, Kaufman MA, Wilson N (1993) Alzheimer-type neuropathology in elderly schizophrenia patients. Schizophr Bull 19:805\u2013816","journal-title":"Schizophr Bull"},{"issue":"7256","key":"436_CR128","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1038\/nature08185","volume":"460","author":"SM Purcell","year":"2009","unstructured":"Purcell SM, Wray NR, Stone JL, Visscher PM, O\u2019Donovan MC, Sullivan PF et al (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460(7256):748\u2013752","journal-title":"Nature"},{"key":"436_CR129","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/S0006-3223(96)89255-9","volume":"40","author":"T Rabinowitz","year":"1996","unstructured":"Rabinowitz T, Frankenburg R, Centorrino F, Kando J (1996) The effect of clozapine on saliva flow rate: a pilot study. Biol Psychiatry 40:1123\u20131134","journal-title":"Biol Psychiatry"},{"key":"436_CR130","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1001\/archpsyc.65.12.1402","volume":"65","author":"S Rathore","year":"2008","unstructured":"Rathore S, Wang Y, Druss B, Masoudi F, Krumholz H (2008) Mental disorders, quality of care, and outcomes in older patients hospitalized with heart failure: an analysis of the national heart failure project. Arch Gen Psychiatry 65:1402\u20131408","journal-title":"Arch Gen Psychiatry"},{"issue":"19","key":"436_CR131","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.1001\/jama.1990.03450190043026","volume":"264","author":"DA Regier","year":"1990","unstructured":"Regier DA, Farmer ME, Rae DS et al (1990) Comorbidity of mental disorders with alcohol and other drug abuse: results from the Epidemiologic Catchment Area (ECA) study. JAMA 264(19):2511\u20132518","journal-title":"JAMA"},{"key":"436_CR132","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1016\/j.ehj.2003.09.008","volume":"24","author":"H Reinecke","year":"2003","unstructured":"Reinecke H, Trey T, Wellmann J, Heidrich J, Fobker M, Wichter T et al (2003) Haemoglobin-related mortality in patients undergoing percutaneous coronary intervention. Eur Heart J 24:2142\u20132150","journal-title":"Eur Heart J"},{"key":"436_CR133","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0920-9964(03)00086-0","volume":"68","author":"LM Ritter","year":"2004","unstructured":"Ritter LM, Meador-Woodruff JH, Dalack GW (2004) Neurocognitive measures of prefrontal cortical dysfunction in schizophrenia. Schizophr Res 68:65\u201373","journal-title":"Schizophr Res"},{"issue":"6","key":"436_CR134","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1097\/00001648-200011000-00002","volume":"11","author":"A Ruigomez","year":"2000","unstructured":"Ruigomez A, GarciaRodriguez LA, Dev VJ, Arellano F, Raniwala J (2000) Are schizophrenia or antipsychotic drugs a risk factor for cataracts? Epidemiology 11(6):620\u2013623","journal-title":"Epidemiology"},{"key":"436_CR135","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1176\/appi.ajp.160.2.284","volume":"160","author":"MC Ryan","year":"2003","unstructured":"Ryan MC, Collins P, Thakore JH (2003) Impaired fasting glucose tolerance in first episode, drug na\u00efve patients with schizophrenia. Am J Psychiatry 160:284\u2013289","journal-title":"Am J Psychiatry"},{"key":"436_CR136","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1001\/archpsyc.64.10.1123","volume":"64","author":"S Saha","year":"2007","unstructured":"Saha S, Chant D, McGrath J (2007) A systematic review of mortality in schizophrenia: is the differential mortality gap worsening over time? Arch Gen Psychiatry 64:1123\u20131131","journal-title":"Arch Gen Psychiatry"},{"issue":"5","key":"436_CR137","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1111\/j.1600-0447.2008.01158.x","volume":"117","author":"S Saddichha","year":"2008","unstructured":"Saddichha S, Manjunatha N, Ameen S, Akhtar S (2008) Diabetes and schizophrenia - effect of disease or drug? Results from a randomized, double-blind, controlled prospective study in first-episode schizophrenia. Acta Psychiatr Scand 117(5):342\u2013347","journal-title":"Acta Psychiatr Scand"},{"key":"436_CR138","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1176\/ajp.153.3.397","volume":"153","author":"S Saravay","year":"1996","unstructured":"Saravay S, Pollack S, Steinberg M, Weinschel B, Habert M (1996) Four year follow-up of the influence of psychological comorbidity on medical rehospitalisation. Am J Psychiatry 153:397\u2013403","journal-title":"Am J Psychiatry"},{"issue":"6","key":"436_CR139","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1177\/070674370905400606","volume":"54","author":"S Satyanarayana","year":"2009","unstructured":"Satyanarayana S et al (2009) Prevalence and correlates of chronic depression in the Canadian community health survey: mental health and well-being. Can J Psychiatry 54(6):389\u2013398","journal-title":"Can J Psychiatry"},{"key":"436_CR140","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1176\/appi.ajp.2010.10111680","volume":"168","author":"MA Schechter","year":"2011","unstructured":"Schechter MA (2011) Nicotine replacement therapy in the psychiatric emergency department. Am J Psychiatry 168:347\u2013349","journal-title":"Am J Psychiatry"},{"issue":"1","key":"436_CR141","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.eurpsy.2011.02.009","volume":"27","author":"D Schoepf","year":"2012","unstructured":"Schoepf D, Potluri R, Uppal H, Natalwala A, Heun R (2012) Type-2 diabetes mellitus in schizophrenia: increased prevalence and major risk factor of excess mortality in a naturalistic 7-year follow up. Eur Psychiatry 27(1):33\u201342","journal-title":"Eur Psychiatry"},{"issue":"3","key":"436_CR142","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s00115-001-1241-8","volume":"74","author":"D Schoepf","year":"2003","unstructured":"Schoepf D, Heun R, Weiffenbach O, Herrmann S, Maier W (2003) The 4-week prevalence of somatoform disorders and associated psychosocial impairment. Nervenarzt 74(3):245\u2013251","journal-title":"Nervenarzt"},{"key":"436_CR143","doi-asserted-by":"crossref","unstructured":"Schuckit MA, Smith TL, Chacko Y (2006) Evaluation of a depression-related model of alcohol problems in 430 probands from the San Diego Prospective Study. Drug Alcohol Depend 82(3):194\u2013203","DOI":"10.1016\/j.drugalcdep.2005.09.006"},{"key":"436_CR144","doi-asserted-by":"crossref","unstructured":"Seldenrijk A, Vogelzangs N, van Oppen P, Penninx B, van Schaik A (2013) Depression, vascular conditions and chronicity. In: Schoepf D (ed) Psychiatric disorders: new frontiers in affective disorders. InTech, pp 279\u2013294. doi: 10.5772\/51623","DOI":"10.5772\/51623"},{"key":"436_CR145","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.schres.2004.03.020","volume":"72","author":"B Shurman","year":"2005","unstructured":"Shurman B, Horan WP, Nuechterlein KH (2005) Schizophrenia patients demonstrate a distinctive pattern of decision-making impairment on the Iowa Gambling Task. Schizophr Res 72:215\u2013224","journal-title":"Schizophr Res"},{"issue":"2","key":"436_CR146","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1097\/00131746-200603000-00004","volume":"12","author":"MK Singh","year":"2006","unstructured":"Singh MK, Giles LL, Nasrallah HA (2006) Pain insensitivity in schizophrenia: trait or state marker? J Psychiatr Pract 12(2):90\u2013102","journal-title":"J Psychiatr Pract"},{"key":"436_CR147","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1176\/appi.ajp.157.9.1379","volume":"157","author":"SG Sirris","year":"2000","unstructured":"Sirris SG (2000) Depression in schizophrenia: perspective in the era of atypical antipsychotic agents. Am J Psychiatry 157:1379\u20131389","journal-title":"Am J Psychiatry"},{"key":"436_CR148","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1192\/bjp.bp.107.037184","volume":"192","author":"M Smith","year":"2008","unstructured":"Smith M, Hopkins D, Peveler RC, Holt RIG, Woodward M, Ismail K (2008) First vs. second-generation antipsychotics and risk for diabetes in schizophrenia: systematic review and meta-analysis. Br J Psychiatry 192:406\u2013411","journal-title":"Br J Psychiatry"},{"issue":"1","key":"436_CR149","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0920-9964(00)00008-6","volume":"47","author":"TN Srinivasan","year":"2001","unstructured":"Srinivasan TN, Thara R, Padmavathi R, McCreadie RG (2001) Relationship of extrapyramidal symptoms to age at onset and drug treatment in middle-aged and elderly schizophrenic patients. Schizophr Res 47(1):69\u201375","journal-title":"Schizophr Res"},{"key":"436_CR150","doi-asserted-by":"crossref","first-page":"425","DOI":"10.4088\/JCP.v60n0701","volume":"60","author":"SM Stahl","year":"1999","unstructured":"Stahl SM (1999) Antipsychotic polypharmacy, part 1. Therapeutic option or dirty little secret. J Clin Psychiatr 60:425\u2013426","journal-title":"J Clin Psychiatr"},{"key":"436_CR151","doi-asserted-by":"crossref","first-page":"313","DOI":"10.2174\/0929867043456070","volume":"11","author":"SM Stahl","year":"2004","unstructured":"Stahl SM, Grady SM (2004) A critical review of atypical antipsychotic utilization: comparing monotherapy with polypharmacy and augmentation. Curr Med Chem 11:313\u2013327. doi: 10.2174\/0929867043456070","journal-title":"Curr Med Chem"},{"issue":"3","key":"436_CR152","first-page":"271","volume":"70","author":"J Steiner","year":"2013","unstructured":"Steiner J, Walter MD et al (2013) Increased prevalence of diverse N-Methyl-D-Aspartate Glutamate receptor antibodies in patients with an initial diagnosis of schizophrenia. Specific relevance of IgG NR1a antibodies for distinction from N-Methyl-D-Aspartate Glutamate receptor encephalitis. JAMA. Psychiatry 70(3):271\u2013278","journal-title":"Psychiatry"},{"issue":"2","key":"436_CR153","doi-asserted-by":"crossref","first-page":"215","DOI":"10.2337\/dc08-s257","volume":"31","author":"AO Stirban","year":"2008","unstructured":"Stirban AO, Tschoepe D (2008) Cardiovascular complications in diabetes: targets and interventions. Diabetes Care 31(2):215\u2013221. doi: 10.2337\/dc08-s257","journal-title":"Diabetes Care"},{"issue":"1","key":"436_CR154","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1097\/PSY.0b013e31827ad512","volume":"75","author":"J Suvisaari","year":"2013","unstructured":"Suvisaari J, Partti K, Per\u00e4l\u00e4 J, Vierti\u00f6 S, Saarni SE, L\u00f6nnqvist J, Saarni SI, H\u00e4rk\u00e4nen T (2013) Mortality and its determinants in people with psychotic disorder. Psychosom Med 75(1):60\u201367","journal-title":"Psychosom Med"},{"key":"436_CR155","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/S1525-5050(03)00160-4","volume":"4","author":"DC Taylor","year":"2003","unstructured":"Taylor DC (2003) Schizophrenia and epilepsies: Why? When? How? Epilepsy Behav 4:474\u2013482","journal-title":"Epilepsy Behav"},{"key":"436_CR156","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/S0140-6736(09)60742-X","volume":"274","author":"J Tiihonen","year":"2009","unstructured":"Tiihonen J, Lonnqvist J, Wahlbeck K, Klaukka T, Niskanen L, Tanskanen A et al (2009) 11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study). Lancet 274:620\u2013627. doi: 10.1016\/S0140-6736(09)60742-X","journal-title":"Lancet"},{"issue":"3","key":"436_CR157","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/YIC.0b013e3283277614","volume":"24","author":"MH Trivedi","year":"2009","unstructured":"Trivedi MH, Corey-Lisle PK et al (2009) Remission, response without remission, and nonresponse in major depressive disorder: impact on functioning. Int Clin Psychopharmcol 24(3):133\u2013138","journal-title":"Int Clin Psychopharmcol"},{"issue":"8","key":"436_CR158","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1023\/A:1025369623365","volume":"18","author":"LJ Ubink-Veltmaat","year":"2003","unstructured":"Ubink-Veltmaat LJ, Bilo HJ, Groenier KH et al (2003) Prevalence, incidence and mortality of type 2 diabetes mellitus revisited: a prospective population-based study in the Netherlands (ZODIAC-1). Eur J Epidemiol 18(8):793\u2013800","journal-title":"Eur J Epidemiol"},{"key":"436_CR159","first-page":"1","volume":"58","author":"A Varma","year":"2010","unstructured":"Varma A, Appleton DL et al (2010) Iron deficiency anaemia and cardiac mortality in patients with left ventricular systolic dysfunction undergoing coronary stenting. Minerva Cardiolangiol 58:1\u201310","journal-title":"Minerva Cardiolangiol"},{"key":"436_CR160","unstructured":"Wahlbeck K, M\u00e4kinen M (2008). Prevention of depression and suicide. Consensus paper. European Communities, Luxembourg. http:\/\/ec.europa.eu\/health\/archive\/ph_determinants\/life_style\/mental\/docs\/consensus_depression_en.pdf"},{"key":"436_CR161","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1176\/appi.ps.60.8.1059","volume":"60","author":"NS Weber","year":"2009","unstructured":"Weber NS, Cowan DN, Millikan AM, Niebuhr DW (2009) Psychiatric and general medical conditions co-morbid with schizophrenia in the national hospital discharge survey. Psychiatr Serv 60:1059\u20131067","journal-title":"Psychiatr Serv"},{"key":"436_CR162","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.2337\/diacare.27.5.1047","volume":"27","author":"S Wild","year":"2004","unstructured":"Wild S, Roglic G, Green A, Sicree R, King H (2004) Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27:1047\u20131053","journal-title":"Diabetes Care"},{"key":"436_CR163","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0895-4356(00)00303-6","volume":"54","author":"JC Will","year":"2001","unstructured":"Will JC, Vinicor F, Stevenson J (2001) Recording of diabetes on death certificates. Has it improved? J Clin Epidemiol 54:239\u2013244","journal-title":"J Clin Epidemiol"},{"key":"436_CR164","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0920-9964(97)00135-7","volume":"30","author":"KE Wilder","year":"1998","unstructured":"Wilder KE, Weinberger DR, Goldberg TE (1998) Operant conditioning and the orbitofrontal cortex in schizophrenic patients: unexpected evidence for intact functioning. Schizophr Res 30:169\u2013174","journal-title":"Schizophr Res"},{"key":"436_CR165","unstructured":"World Health Organisation (1999) Definition, diagnosis and classification of diabetes mellitus and its complications: Part 1. Diagnosis and classification of diabetes mellitus. World Health Organisation. http:\/\/www.aacc.org\/sitecollectiondocuments\/nacb\/lmpg\/diabetes\/1107_diabetesupdate_draftguidelines.pdf"},{"key":"436_CR166","unstructured":"Wu JH, Dickson M, Durkin M, Canuso CM (2007) Treated liver disease in Medicaid recipients with schizophrenia or bipolar disorder. Primary Psychiatry 14 (10):71\u201379. http:\/\/www.primarypsychiatry.com\/aspx\/articledetail.aspx?articleid=1282"},{"issue":"24","key":"436_CR167","first-page":"3198","volume":"283","author":"JK Young","year":"2000","unstructured":"Young JK, Forster DA (2000) Cardiovascular procedures in mental disorders. JAMA 283(24):3198\u20133199. doi: 10.1001\/jama.283.24.3198","journal-title":"JAMA"},{"issue":"2","key":"436_CR168","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1093\/schbul\/23.2.247","volume":"23","author":"DM Ziedonis","year":"1997","unstructured":"Ziedonis DM, George TP (1997) Schizophrenia and nicotine use: report of a pilot smoking cessation program and review of neurobiological and clinical issues. Schizophr Bull 23(2):247\u2013253","journal-title":"Schizophr Bull"}],"container-title":["European Archives of Psychiatry and Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00406-013-0436-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00406-013-0436-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00406-013-0436-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T17:03:57Z","timestamp":1596301437000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00406-013-0436-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,13]]},"references-count":168,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["436"],"URL":"https:\/\/doi.org\/10.1007\/s00406-013-0436-x","relation":{},"ISSN":["0940-1334","1433-8491"],"issn-type":[{"value":"0940-1334","type":"print"},{"value":"1433-8491","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,13]]}}}