{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T17:45:51Z","timestamp":1787852751293,"version":"build-2784847793"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2018,6,7]],"date-time":"2018-06-07T00:00:00Z","timestamp":1528329600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2018,6,7]],"date-time":"2018-06-07T00:00:00Z","timestamp":1528329600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81771159"],"award-info":[{"award-number":["81771159"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81500931"],"award-info":[{"award-number":["81500931"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81703482"],"award-info":[{"award-number":["81703482"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP17dm0107119"],"award-info":[{"award-number":["JP17dm0107119"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Psychiatry Clin Neurosci"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1007\/s00406-018-0909-z","type":"journal-article","created":{"date-parts":[[2018,6,7]],"date-time":"2018-06-07T06:24:28Z","timestamp":1528352668000},"page":"195-205","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Brain-derived neurotrophic factor-TrkB signaling in the medial prefrontal cortex plays a role in the anhedonia-like phenotype after spared nerve injury"],"prefix":"10.1007","volume":"270","author":[{"given":"Xi","family":"Fang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaofeng","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niannian","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangxi","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ailin","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,6,7]]},"reference":[{"key":"909_CR1","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1001\/archinte.163.20.2433","volume":"163","author":"MJ Bair","year":"2003","unstructured":"Bair MJ, Robinson RL, Katon W, Kroenke K (2003) Depression and pain comorbidity: a literature review. Arch Intern Med 163:2433\u20132445","journal-title":"Arch Intern Med"},{"key":"909_CR2","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1124\/pr.113.008144","volume":"66","author":"AK Walker","year":"2014","unstructured":"Walker AK, Kavelaars A, Heijnen CJ, Dantzer R (2014) Neuroinflammation and comorbidity of pain and depression. Pharmacol Rev 66:80\u2013101","journal-title":"Pharmacol Rev"},{"key":"909_CR3","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.bbr.2014.04.042","volume":"276","author":"JX Li","year":"2015","unstructured":"Li JX (2015) Pain and depression comorbidity: a preclinical perspective. Behav Brain Res 276:92\u201398","journal-title":"Behav Brain Res"},{"key":"909_CR4","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1002\/j.1532-2149.2013.00334.x","volume":"17","author":"F Radat","year":"2013","unstructured":"Radat F, Margot-Duclot A, Attal N (2013) Psychiatric co-morbidities in patients with chronic peripheral neuropathic pain: a multicentre cohort study. Eur J Pain 17:1547\u20131557","journal-title":"Eur J Pain"},{"key":"909_CR5","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1111\/j.1399-6576.2007.01486.x","volume":"52","author":"B Gustorff","year":"2008","unstructured":"Gustorff B, Dorner T, Likar R, Grisold W, Lawrence K, Schwarz F et al (2008) Prevalence of self-reported neuropathic pain and impact on quality of life: a prospective representative survey. Acta Anaesthesiol Scand 52:132\u2013136","journal-title":"Acta Anaesthesiol Scand"},{"key":"909_CR6","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.jpain.2011.03.003","volume":"12","author":"K Kroenke","year":"2011","unstructured":"Kroenke K, Wu J, Bair MJ, Krebs EE, Damush TM, Tu W (2011) Reciprocal relationship between pain and depression: a 12-month longitudinal analysis in primary care. J Pain 12:964\u2013973","journal-title":"J Pain"},{"key":"909_CR7","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.neulet.2003.12.010","volume":"361","author":"KA Keay","year":"2004","unstructured":"Keay KA, Monassi CR, Levison DB, Bandler R (2004) Peripheral nerve injury evokes disabilities and sensory dysfunction in a subpopulation of rats: a closer model to human chronic neuropathic pain? Neurosci Lett 361:188\u2013191","journal-title":"Neurosci Lett"},{"key":"909_CR8","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1046\/j.1460-9568.2003.02627.x","volume":"17","author":"CR Monassi","year":"2003","unstructured":"Monassi CR, Bandler R. Keay KA (2003) A subpopulation of rats show social and sleep-waking changes typical of chronic neuropathic pain following peripheral nerve injury. Eur J Neurosci 17:1907\u20131920","journal-title":"Eur J Neurosci"},{"key":"909_CR9","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1089\/neu.2013.3204","volume":"31","author":"K Luedtke","year":"2014","unstructured":"Luedtke K, Bouchard SM, Woller SA, Funk MK, Aceves M, Hook MA (2014) Assessment of depression in a rodent model of spinal cord injury. J Neurotrauma 31:1107\u20131121","journal-title":"J Neurotrauma"},{"key":"909_CR10","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0896-6273(02)00653-0","volume":"34","author":"EJ Nestler","year":"2002","unstructured":"Nestler EJ, Barrot M, DiLeone RJ, Eisch AJ, Gold SJ, Monteggia LM (2002) Neurobiology of depression. Neuron 34:13\u201325","journal-title":"Neuron"},{"key":"909_CR11","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.brainresrev.2004.02.003","volume":"45","author":"K Hashimoto","year":"2004","unstructured":"Hashimoto K, Shimizu E, Iyo M (2004) Critical role of brain-derived neurotrophic factor in mood disorders. Brain Res Brain Res Rev 45:104\u2013114","journal-title":"Brain Res Brain Res Rev"},{"key":"909_CR12","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1016\/j.biopsych.2006.02.013","volume":"59","author":"RS Duman","year":"2006","unstructured":"Duman RS, Monteggia LM (2006) A neurotrophic model for stress-related mood disorders. Biol Psychiatry 59:1116\u20131127","journal-title":"Biol Psychiatry"},{"key":"909_CR13","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1038\/nn1971","volume":"10","author":"K Martinowich","year":"2007","unstructured":"Martinowich K, Manji H, Lu B (2007) New insights into BDNF function in depression and anxiety. Nat Neurosci 10:1089\u20131093","journal-title":"Nat Neurosci"},{"key":"909_CR14","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1440-1819.2010.02113.x","volume":"64","author":"K Hashimoto","year":"2010","unstructured":"Hashimoto K (2010) Brain-derived neurotrophic factor as a biomarker for mood disorders: an historical overview and future directions. Psychiatry Clin Neurosci 64:341\u2013357","journal-title":"Psychiatry Clin Neurosci"},{"key":"909_CR15","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.pneurobio.2012.09.001","volume":"100","author":"K Hashimoto","year":"2013","unstructured":"Hashimoto K (2013) Sigma-1 receptor chaperone and brain-derived neurotrophic factor: emerging links between cardiovascular disease and depression. Prog Neurobiol 100:15\u201329","journal-title":"Prog Neurobiol"},{"key":"909_CR16","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/978-3-642-45106-5_17","volume":"220","author":"E Castr\u00e9n","year":"2014","unstructured":"Castr\u00e9n E (2014) Neurotrophins and psychiatric disorders. Handb Exp Pharmacol 220:461\u2013479","journal-title":"Handb Exp Pharmacol"},{"key":"909_CR17","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.neuropharm.2015.10.034","volume":"102","author":"C Bj\u00f6rkholm","year":"2016","unstructured":"Bj\u00f6rkholm C, Monteggia LM (2016) BDNF\u2014a key transducer of antidepressant effects. Neuropharmacology 102:72\u201379","journal-title":"Neuropharmacology"},{"key":"909_CR18","doi-asserted-by":"crossref","first-page":"721","DOI":"10.2174\/1570159X14666160119094646","volume":"14","author":"JC Zhang","year":"2016","unstructured":"Zhang JC, Yao W, Hashimoto K (2016) Brain-derived neurotrophic factor (BDNF)-TrkB signaling in inflammation-related depression and potential therapeutic targets. Curr Neuropharmacol 14:721\u2013731","journal-title":"Curr Neuropharmacol"},{"key":"909_CR19","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/s00213-015-4128-2","volume":"233","author":"WX Liu","year":"2016","unstructured":"Liu WX, Wang J, Xie ZM, Xu N, Zhang GF, Jia M et al (2016) Regulation of glutamate transporter 1 via BDNF-TrkB signaling plays a role in the anti-apoptotic and antidepressant effects of ketamine in chronic unpredictable stress model of depression. Psychopharmacology 233:405\u2013415","journal-title":"Psychopharmacology"},{"key":"909_CR20","first-page":"pyu077","volume":"18","author":"JC Zhang","year":"2014","unstructured":"Zhang JC, Wu J, Fujita Y, Yao W, Ren Q, Yang Q et al (2014) Antidepressant effects of TrkB ligands on depression-like behavior and dendritic changes in mice after inflammation. Int J Neuropsychopharmacol 18:pyu077","journal-title":"Int J Neuropsychopharmacol"},{"key":"909_CR21","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.jnutbio.2016.10.004","volume":"39","author":"JC Zhang","year":"2017","unstructured":"Zhang JC, Yao W, Dong C, Yang C, Ren Q, Ma M et al (2017) Prophylactic effects of sulforaphane on depression-like behavior and dendritic changes in mice after inflammation. J Nutr Biochem 39:134\u2013144","journal-title":"J Nutr Biochem"},{"key":"909_CR22","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s00213-016-4483-7","volume":"234","author":"M Ma","year":"2017","unstructured":"Ma M, Ren Q, Yang C, Zhang JC, Yao W, Dong C et al (2017) Antidepressant effects of combination of brexpiprazole and fluoxetine on depression-like behavior and dendritic changes in mice after inflammation. Psychopharmacology 234:525\u2013533","journal-title":"Psychopharmacology"},{"key":"909_CR23","doi-asserted-by":"crossref","first-page":"e632","DOI":"10.1038\/tp.2015.136","volume":"5","author":"C Yang","year":"2015","unstructured":"Yang C, Shirayama Y, Zhang JC, Ren Q, Yao W, Ma M et al (2015) R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects. Transl Psychiatry 5:e632","journal-title":"Transl Psychiatry"},{"key":"909_CR24","doi-asserted-by":"crossref","first-page":"39209","DOI":"10.1038\/srep39209","volume":"6","author":"M Ma","year":"2016","unstructured":"Ma M, Ren Q, Yang C, Zhang JC, Yao W, Dong C et al (2016) Adjunctive treatment of brexpiprazole with fluoxetine shows a rapid antidepressant effect in social defeat stress model: role of BDNF-TrkB signaling. Sci Rep 6:39209","journal-title":"Sci Rep"},{"key":"909_CR25","first-page":"228","volume":"20","author":"C Dong","year":"2017","unstructured":"Dong C, Zhang JC, Yao W, Ren Q, Ma M, Yang C et al (2017) Rapid and sustained antidepressant action of the mGlu2\/3 receptor antagonist MGS0039 in the social defeat stress model: comparison with ketamine. Int J Neuropsychopharmacol 20:228\u2013236","journal-title":"Int J Neuropsychopharmacol"},{"key":"909_CR26","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1016\/j.euroneuro.2015.09.002","volume":"25","author":"Y Shirayama","year":"2015","unstructured":"Shirayama Y, Yang C, Zhang JC, Ren Q, Yao W, Hashimoto K (2015) Alterations in brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in the brain regions of a learned helplessness rat model and antidepressant effects of TrkB agonist and antagonist. Eur Neuropsychopharmacol 25:2449\u20132458","journal-title":"Eur Neuropsychopharmacol"},{"key":"909_CR27","doi-asserted-by":"crossref","first-page":"pyu121","DOI":"10.1093\/ijnp\/pyu121","volume":"18","author":"C Yang","year":"2015","unstructured":"Yang C, Shirayama Y, Zhang JC, Ren Q, Hashimoto K (2015) Regional differences in brain-derived neurotrophic factor levels and dendritic spine density confer resilience to inescapable stress. Int J Neuropsychopharmacol 18:pyu121","journal-title":"Int J Neuropsychopharmacol"},{"key":"909_CR28","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1007\/s00406-016-0693-6","volume":"266","author":"B Yang","year":"2016","unstructured":"Yang B, Yang C, Ren Q, Zhang JC, Chen QX, Shirayama Y et al (2016) Regional differences in the expression of brain-derived neurotrophic factor (BDNF) pro-peptide, proBDNF and preproBDNF in the brain confer stress resilience. Eur Arch Psychiatry Clin Neurosci 266:765\u2013769","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"909_CR29","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.pneurobio.2008.04.004","volume":"85","author":"A Merighi","year":"2008","unstructured":"Merighi A, Salio C, Ghirri A, Lossi L, Ferrini F, Betelli C et al (2008) BDNF as a pain modulator. Prog Neurobiol 85:297\u2013317","journal-title":"Prog Neurobiol"},{"key":"909_CR30","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1017\/S1740925X12000087","volume":"7","author":"T Trang","year":"2011","unstructured":"Trang T, Beggs S, Salter MW (2011) Brain-derived neurotrophic factor from microglia: a molecular substrate for neuropathic pain. Neuron Glia Biol 7:99\u2013108","journal-title":"Neuron Glia Biol"},{"key":"909_CR31","doi-asserted-by":"crossref","first-page":"3124","DOI":"10.1038\/s41598-017-03590-3","volume":"7","author":"ZM Xie","year":"2017","unstructured":"Xie ZM, Wang XM, Xu N, Wang J, Pan W, Tang XH et al (2017) Alterations in the inflammatory cytokines and brain-derived neurotrophic factor contribute to depression-like phenotype after spared nerve injury: improvement by ketamine. Sci Rep 7:3124","journal-title":"Sci Rep"},{"key":"909_CR32","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1034\/j.1600-0447.2001.103002122.x","volume":"103","author":"J Spijker","year":"2001","unstructured":"Spijker J, Bijl RV, De Graaf R, Nolen WA (2001) Determinants of poor 1-year outcome of DSM-III-R major depression in the general population: results of The Netherlands mental health survey and incidence study (NEMESIS). Acta Psychiatr Scand 103:122\u2013130","journal-title":"Acta Psychiatr Scand"},{"key":"909_CR33","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.jaac.2012.01.011","volume":"51","author":"DL McMakin","year":"2012","unstructured":"McMakin DL, Olino TM, Porta G, Dietz LJ, Emslie G, Clarke G et al (2012) Anhedonia predicts poorer recovery among youth with selective serotonin reuptake inhibitor treatment\u2013resistant depression. J Am Acad Child Adolesc Psychiatry 51:404\u2013411","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"909_CR34","doi-asserted-by":"crossref","first-page":"2687","DOI":"10.1073\/pnas.0913572107","volume":"107","author":"SW Jang","year":"2010","unstructured":"Jang SW, Liu X, Yepes M, Stepherd KR, Miller GW, Liu Y et al (2010) A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone. Proc Natl Acad Sci USA 107:2687\u20132692","journal-title":"Proc Natl Acad Sci USA"},{"key":"909_CR35","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1172\/JCI43992","volume":"121","author":"M Cazorla","year":"2011","unstructured":"Cazorla M, Pr\u00e9mont J, Mann A, Girard N, Kellendonk C, Rognan D (2011) Identification of a low\u2013molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice. J Clin Invest 121:1846\u20131857","journal-title":"J Clin Invest"},{"key":"909_CR36","doi-asserted-by":"crossref","first-page":"e666","DOI":"10.1038\/tp.2015.157","volume":"5","author":"Q Ren","year":"2015","unstructured":"Ren Q, Ma M, Yang C, Zhang JC, Yao W, Hashimoto K (2015) BDNF-TrkB signaling in the nucleus accumbens shell of mice has key role in methamphetamine withdrawal symptoms. Transl Psychiatry 5:e666","journal-title":"Transl Psychiatry"},{"key":"909_CR37","doi-asserted-by":"crossref","unstructured":"Fang X, Zhan G, Zhang J, Xu H, Zhu B, Hu Y et al (2018) Abnormalities in inflammatory cytokines confer susceptible to chronic neuropathic pain-related anhedonia in a rat model of spared nerve injury. Clin Psychopharmacol Neurosci (in press)","DOI":"10.9758\/cpn.2019.17.2.189"},{"key":"909_CR38","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/s12974-015-0318-4","volume":"12","author":"PJ Austin","year":"2015","unstructured":"Austin PJ, Berglund AM, Siu S, Fiore NT, Gerke-Duncan MB, Ollerenshaw SL et al (2015) Evidence for a distinct neuro-immune signature in rats that develop behavioural disability after nerve injury. J Neuroinflamm 12:96","journal-title":"J Neuroinflamm"},{"key":"909_CR39","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.neuroscience.2010.08.040","volume":"171","author":"PJ Austin","year":"2010","unstructured":"Austin PJ, Beyer K, Bembrick AL, Keay KA (2010) Peripheral nerve injury differentially regulates dopaminergic pathways in the nucleus accumbens of rats with either \u2018pain alone\u2019 or \u2018pain and disability\u2019. Neuroscience 171:329\u2013343","journal-title":"Neuroscience"},{"key":"909_CR40","first-page":"12","volume":"12","author":"WS Gui","year":"2016","unstructured":"Gui WS, Wei X, Mai CL, Murugan M, Wu LJ, Xin WJ et al (2016) Interleukin-1\u03b2 overproduction is a common cause for neuropathic pain, memory deficit, and depression following peripheral nerve injury in rodents. Mol Pain 12:12","journal-title":"Mol Pain"},{"key":"909_CR41","doi-asserted-by":"crossref","first-page":"e741","DOI":"10.1038\/tp.2016.21","volume":"6","author":"HL Sun","year":"2016","unstructured":"Sun HL, Zhou ZQ, Zhang GF, Yang C, Wang XM, Shen JC et al (2016) Role of hippocampal p11 in the sustained antidepressant effect of ketamine in the chronic unpredictable mild stress model. Transl Psychiatry 6:e741","journal-title":"Transl Psychiatry"},{"key":"909_CR42","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1007\/BF02532343","volume":"21","author":"M Yamamoto","year":"1996","unstructured":"Yamamoto M. Sobue G, Yamamoto K, Terao S, Mitsuma T (1996) Expression of mRNAs for neurotrophic factors (NGF, BDNF, NT-3, and GDNF) and their receptors (p75NGFR, trkA, trkB, and trkC) in the adult human peripheral nervous system and nonneural tissues. Neurochem Res 21:929\u2013938","journal-title":"Neurochem Res"},{"key":"909_CR43","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1053\/jhep.2001.20793","volume":"33","author":"D Cassiman","year":"2001","unstructured":"Cassiman D, Denef C, Desmer VJ, Roskams T (2001) Human and rat hepatic stellate cells express neurotrophins and neurotrophin receptors. Hepatology 33:148\u2013158","journal-title":"Hepatology"},{"key":"909_CR44","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1158\/0008-5472.219.65.1","volume":"65","author":"ZF Yang","year":"2005","unstructured":"Yang ZF, Ho DW, Lam CT, Luk JM, Lum CT, Yu WC et al (2005) Identification of brain-derived neurotrophic factor as a novel functional protein in hepatocellular carcinoma. Cancer Res 65:219\u2013225","journal-title":"Cancer Res"},{"key":"909_CR45","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.mce.2016.04.015","volume":"430","author":"Y Genzer","year":"2016","unstructured":"Genzer Y, Dadon M, Burg C, Chapnik N, O (2016) Effect of dietary fat and the circadian clock on the expression of brain-derived neurotrophic factor (BDNF). Mol Cell Endocrinol 430:49\u201355","journal-title":"Mol Cell Endocrinol"},{"key":"909_CR46","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3389\/fnmol.2017.00147","volume":"10","author":"E Hurtado","year":"2017","unstructured":"Hurtado E, Cilleros V, Nadal L, Sim\u00f3 A, Obis T, Garcia N et al (2017) Muscle contraction regulates BDNF\/TrkB signaling to modulate synaptic function through presynaptic cPKC\u03b1 and cPKC\u03b2I. Front Mol Neurosci 10:147","journal-title":"Front Mol Neurosci"},{"key":"909_CR47","doi-asserted-by":"crossref","first-page":"e1128","DOI":"10.1038\/tp.2017.95","volume":"7","author":"B Yang","year":"2017","unstructured":"Yang B, Ren Q, Zhang JC, Chen QX, Hashimoto K (2017) Altered expression of BDNF, BDNF pro-peptide and their precursor proBDNF in brain and liver tissues from psychiatric disorders: rethinking the brain-liver axis. Transl Psychiatry 7:e1128","journal-title":"Transl Psychiatry"},{"key":"909_CR48","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1517\/14728222.2014.994506","volume":"19","author":"J Nijs","year":"2015","unstructured":"Nijs J, Meeus M, Versijpt J, Moens M, Bos I, Knaepen K et al (2015) Brain-derived neurotrophic factor as a driving force behind neuroplasticity in neuropathic and central sensitization pain: a new therapeutic target? Expert Opin Ther Targets 19:565\u2013576","journal-title":"Expert Opin Ther Targets"},{"key":"909_CR49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2017.03.029","volume":"1665","author":"H Zhao","year":"2017","unstructured":"Zhao H, Alam A, San CY, Eguchi S, Chen Q, Lian Q et al (2017) Molecular mechanisms of brain-derived neurotrophic factor in neuro-protection: Recent developments. Brain Res 1665:1\u201321","journal-title":"Brain Res"}],"container-title":["European Archives of Psychiatry and Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00406-018-0909-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00406-018-0909-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00406-018-0909-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,7]],"date-time":"2024-07-07T09:46:41Z","timestamp":1720345601000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00406-018-0909-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,7]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["909"],"URL":"https:\/\/doi.org\/10.1007\/s00406-018-0909-z","relation":{},"ISSN":["0940-1334","1433-8491"],"issn-type":[{"value":"0940-1334","type":"print"},{"value":"1433-8491","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,7]]},"assertion":[{"value":"11 April 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 May 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 June 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Dr. Chun Yang received the research support from B. Braun Medical Inc. Other authors declared no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}