{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:18:16Z","timestamp":1791332296495,"version":"4.3.1"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T00:00:00Z","timestamp":1648080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T00:00:00Z","timestamp":1648080000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Psychiatry Clin Neurosci"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1007\/s00406-021-01361-w","type":"journal-article","created":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T17:46:31Z","timestamp":1648230391000},"page":"541-551","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Diagnostic progression to schizophrenia in 35,255 patients with obsessive\u2013compulsive disorder: a longitudinal follow-up study"],"prefix":"10.1007","volume":"273","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6516-1073","authenticated-orcid":false,"given":"Mu-Hong","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Jen","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Sung","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Ming","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tung-Ping","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tzeng-Ji","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Mei","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,24]]},"reference":[{"key":"1361_CR1","doi-asserted-by":"publisher","first-page":"86","DOI":"10.5498\/wjp.v2.i6.86","volume":"2","author":"CW Lack","year":"2012","unstructured":"Lack CW (2012) Obsessive-compulsive disorder: evidence-based treatments and future directions for research. World J Psychiatry 2:86\u201390","journal-title":"World J Psychiatry"},{"key":"1361_CR2","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/j.psc.2014.06.004","volume":"37","author":"WK Goodman","year":"2014","unstructured":"Goodman WK, Grice DE, Lapidus KA, Coffey BJ (2014) Obsessive\u2013compulsive disorder. Psychiatr Clin North Am 37:257\u2013267","journal-title":"Psychiatr Clin North Am"},{"key":"1361_CR3","first-page":"445","volume":"74","author":"CJ Murray","year":"1996","unstructured":"Murray CJ, Lopez AD (1996) The incremental effect of age-weighting on YLLs, YLDs, and DALYs: a response. Bull World Health Organ 74:445\u2013446","journal-title":"Bull World Health Organ"},{"key":"1361_CR4","doi-asserted-by":"publisher","first-page":"2363","DOI":"10.1017\/S0033291713003243","volume":"44","author":"AJ Baxter","year":"2014","unstructured":"Baxter AJ, Vos T, Scott KM, Ferrari AJ, Whiteford HA (2014) The global burden of anxiety disorders in 2010. Psychol Med 44:2363\u20132374","journal-title":"Psychol Med"},{"key":"1361_CR5","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1001\/archpsyc.62.6.593","volume":"62","author":"RC Kessler","year":"2005","unstructured":"Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE (2005) Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 62:593\u2013602","journal-title":"Arch Gen Psychiatry"},{"key":"1361_CR6","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.schres.2019.05.024","volume":"209","author":"YF Cheng","year":"2019","unstructured":"Cheng YF, Chen VC, Yang YH, Chen KJ, Lee YC, Lu ML (2019) Risk of schizophrenia among people with obsessive-compulsive disorder: a nationwide population-based cohort study. Schizophr Res 209:58\u201363","journal-title":"Schizophr Res"},{"key":"1361_CR7","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1001\/jamapsychiatry.2014.1011","volume":"71","author":"SM Meier","year":"2014","unstructured":"Meier SM, Petersen L, Pedersen MG, Arendt MC, Nielsen PR, Mattheisen M, Mors O, Mortensen PB (2014) Obsessive-compulsive disorder as a risk factor for schizophrenia: a nationwide study. JAMA Psychiat 71:1215\u20131221","journal-title":"JAMA Psychiat"},{"key":"1361_CR8","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1111\/j.1751-7893.2012.00357.x","volume":"6","author":"LF Fontenelle","year":"2012","unstructured":"Fontenelle LF, Lin A, Pantelis C, Wood SJ, Nelson B, Yung AR (2012) Markers of vulnerability to obsessive-compulsive disorder in an ultra-high risk sample of patients who developed psychosis. Early Interv Psychiatry 6:201\u2013206","journal-title":"Early Interv Psychiatry"},{"key":"1361_CR9","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.1016\/j.jpsychires.2011.03.005","volume":"45","author":"LF Fontenelle","year":"2011","unstructured":"Fontenelle LF, Lin A, Pantelis C, Wood SJ, Nelson B, Yung AR (2011) A longitudinal study of obsessive-compulsive disorder in individuals at ultra-high risk for psychosis. J Psychiatr Res 45:1140\u20131145","journal-title":"J Psychiatr Res"},{"key":"1361_CR10","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1080\/j.1440-1614.2005.01714.x","volume":"39","author":"AR Yung","year":"2005","unstructured":"Yung AR, Yuen HP, McGorry PD, Phillips LJ, Kelly D, Dell\u2019Olio M, Francey SM, Cosgrave EM, Killackey E, Stanford C, Godfrey K, Buckby J (2005) Mapping the onset of psychosis: the comprehensive assessment of at-risk mental states. Aust N Z J Psychiatry 39:964\u2013971","journal-title":"Aust N Z J Psychiatry"},{"key":"1361_CR11","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1176\/appi.ajp.2019.18091085","volume":"176","author":"AB Zheutlin","year":"2019","unstructured":"Zheutlin AB, Dennis J, Karlsson Linner R, Moscati A, Restrepo N, Straub P, Ruderfer D, Castro VM, Chen CY, Ge T, Huckins LM, Charney A, Kirchner HL, Stahl EA, Chabris CF, Davis LK, Smoller JW (2019) Penetrance and pleiotropy of polygenic risk scores for schizophrenia in 106,160 patients across four health care systems. Am J Psychiatry 176:846\u2013855","journal-title":"Am J Psychiatry"},{"key":"1361_CR12","doi-asserted-by":"publisher","first-page":"1603","DOI":"10.1111\/epi.14508","volume":"59","author":"KC Rossi","year":"2018","unstructured":"Rossi KC, Kim AM, Jette N, Yoo JY, Hung K, Dhamoon MS (2018) Increased risk of hospital admission for ICD-9-CM psychotic episodes following admission for epilepsy. Epilepsia 59:1603\u20131611","journal-title":"Epilepsia"},{"key":"1361_CR13","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.schres.2012.02.019","volume":"138","author":"MS Pedersen","year":"2012","unstructured":"Pedersen MS, Benros ME, Agerbo E, Borglum AD, Mortensen PB (2012) Schizophrenia in patients with atopic disorders with particular emphasis on asthma: a Danish population-based study. Schizophr Res 138:58\u201362","journal-title":"Schizophr Res"},{"key":"1361_CR14","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1017\/S2045796016000561","volume":"26","author":"S Tiosano","year":"2017","unstructured":"Tiosano S, Farhi A, Watad A, Grysman N, Stryjer R, Amital H, Comaneshter D, Cohen AD, Amital D (2017) Schizophrenia among patients with systemic lupus erythematosus: population-based cross-sectional study. Epidemiol Psychiatr Sci 26:424\u2013429","journal-title":"Epidemiol Psychiatr Sci"},{"key":"1361_CR15","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1192\/bjp.bp.113.143610","volume":"206","author":"MH Chen","year":"2015","unstructured":"Chen MH, Pan TL, Li CT, Lin WC, Chen YS, Lee YC, Tsai SJ, Hsu JW, Huang KL, Tsai CF, Chang WH, Chen TJ, Su TP, Bai YM (2015) Risk of stroke among patients with post-traumatic stress disorder: nationwide longitudinal study. Br J Psychiatry 206:302\u2013307","journal-title":"Br J Psychiatry"},{"key":"1361_CR16","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1111\/jcpp.12018","volume":"54","author":"MH Chen","year":"2013","unstructured":"Chen MH, Su TP, Chen YS, Hsu JW, Huang KL, Chang WH, Bai YM (2013) Attention deficit hyperactivity disorder, tic disorder, and allergy: is there a link? A nationwide population-based study. J Child Psychol Psychiatry 54:545\u2013551","journal-title":"J Child Psychol Psychiatry"},{"key":"1361_CR17","doi-asserted-by":"publisher","first-page":"1756","DOI":"10.1038\/mp.2017.217","volume":"23","author":"CM Cheng","year":"2018","unstructured":"Cheng CM, Chang WH, Chen MH, Tsai CF, Su TP, Li CT, Tsai SJ, Hsu JW, Huang KL, Lin WC, Chen TJ, Bai YM (2018) Co-aggregation of major psychiatric disorders in individuals with first-degree relatives with schizophrenia: a nationwide population-based study. Mol Psychiatry 23:1756\u20131763","journal-title":"Mol Psychiatry"},{"key":"1361_CR18","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1093\/schbul\/sbz126","volume":"46","author":"CS Liang","year":"2020","unstructured":"Liang CS, Bai YM, Hsu JW, Huang KL, Ko NY, Chu HT, Yeh TC, Tsai SJ, Chen TJ, Chen MH (2020) The risk of sexually transmitted infections following first-episode schizophrenia among adolescents and young adults: a cohort study of 220 545 subjects. Schizophr Bull 46:795\u2013803","journal-title":"Schizophr Bull"},{"key":"1361_CR19","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/S0140-6736(15)01121-6","volume":"388","author":"MJ Owen","year":"2016","unstructured":"Owen MJ, Sawa A, Mortensen PB (2016) Schizophrenia. Lancet 388:86\u201397","journal-title":"Lancet"},{"key":"1361_CR20","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","volume":"40","author":"ME Charlson","year":"1987","unstructured":"Charlson ME, Pompei P, Ales KL, MacKenzie CR (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373\u2013383","journal-title":"J Chronic Dis"},{"key":"1361_CR21","first-page":"1","volume":"4","author":"CY Liu","year":"2006","unstructured":"Liu CY, Hung YT, Chuang YL, Chen YJ, Weng WS, Liu JS (2006) Incorporating development stratification of Taiwan townships into sampling design of large scale health interview survey. J Health Management (Chin) 4:1\u201322","journal-title":"J Health Management (Chin)"},{"key":"1361_CR22","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1093\/schbul\/sbu169","volume":"41","author":"M Cederlof","year":"2015","unstructured":"Cederlof M, Lichtenstein P, Larsson H, Boman M, Ruck C, Landen M, Mataix-Cols D (2015) Obsessive\u2013compulsive disorder, psychosis, and bipolarity: a longitudinal cohort and multigenerational family study. Schizophr Bull 41:1076\u20131083","journal-title":"Schizophr Bull"},{"key":"1361_CR23","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1016\/j.schres.2013.10.033","volume":"152","author":"M Swets","year":"2014","unstructured":"Swets M, Dekker J, van Emmerik-van OK, Smid GE, Smit F, de Haan L, Schoevers RA (2014) The obsessive compulsive spectrum in schizophrenia, a meta-analysis and meta-regression exploring prevalence rates. Schizophr Res 152:458\u2013468","journal-title":"Schizophr Res"},{"key":"1361_CR24","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.psychres.2012.02.024","volume":"197","author":"S Faragian","year":"2012","unstructured":"Faragian S, Fuchs C, Pashinian A, Weizman R, Weizman A, Poyurovsky M (2012) Age-of-onset of schizophrenic and obsessive-compulsive symptoms in patients with schizo-obsessive disorder. Psychiatry Res 197:19\u201322","journal-title":"Psychiatry Res"},{"key":"1361_CR25","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.3390\/jcm8091304","volume":"8","author":"R De Giorgi","year":"2019","unstructured":"De Giorgi R, De Crescenzo F, D\u2019Alo GL, Rizzo Pesci N, Di Franco V, Sandini C, Armando M (2019) Prevalence of non-affective psychoses in individuals with autism spectrum disorders: a systematic review. J Clin Med 8:1304","journal-title":"J Clin Med"},{"key":"1361_CR26","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1097\/CHI.0b013e31818b1c63","volume":"48","author":"J Rapoport","year":"2009","unstructured":"Rapoport J, Chavez A, Greenstein D, Addington A, Gogtay N (2009) Autism spectrum disorders and childhood-onset schizophrenia: clinical and biological contributions to a relation revisited. J Am Acad Child Adolesc Psychiatry 48:10\u201318","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"1361_CR27","first-page":"891","volume":"111","author":"O Stahlberg","year":"2004","unstructured":"Stahlberg O, Soderstrom H, Rastam M, Gillberg C (2004) Bipolar disorder, schizophrenia, and other psychotic disorders in adults with childhood onset AD\/HD and\/or autism spectrum disorders. J Neural Transm (Vienna) 111:891\u2013902","journal-title":"J Neural Transm (Vienna)"},{"issue":"Suppl 2","key":"1361_CR28","doi-asserted-by":"publisher","first-page":"S396","DOI":"10.1093\/schbul\/sbu176","volume":"41","author":"M Debbane","year":"2015","unstructured":"Debbane M, Eliez S, Badoud D, Conus P, Fluckiger R, Schultze-Lutter F (2015) Developing psychosis and its risk states through the lens of schizotypy. Schizophr Bull 41(Suppl 2):S396-407","journal-title":"Schizophr Bull"},{"key":"1361_CR29","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1111\/eip.12518","volume":"13","author":"M Bang","year":"2019","unstructured":"Bang M, Park JY, Kim KR, Lee SY, Song YY, Kang JI, Lee E, An SK (2019) Psychotic conversion of individuals at ultra-high risk for psychosis: the potential roles of schizotypy and basic symptoms. Early Interv Psychiatry 13:546\u2013554","journal-title":"Early Interv Psychiatry"},{"key":"1361_CR30","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1093\/schbul\/sbw082","volume":"43","author":"N Okkels","year":"2017","unstructured":"Okkels N, Trabjerg B, Arendt M, Pedersen CB (2017) Traumatic stress disorders and risk of subsequent schizophrenia spectrum disorder or bipolar disorder: a nationwide cohort study. Schizophr Bull 43:180\u2013186","journal-title":"Schizophr Bull"},{"key":"1361_CR31","doi-asserted-by":"publisher","first-page":"274","DOI":"10.3389\/fnins.2019.00274","volume":"13","author":"D Popovic","year":"2019","unstructured":"Popovic D, Schmitt A, Kaurani L, Senner F, Papiol S, Malchow B, Fischer A, Schulze TG, Koutsouleris N, Falkai P (2019) Childhood trauma in schizophrenia: current findings and research perspectives. Front Neurosci 13:274","journal-title":"Front Neurosci"},{"key":"1361_CR32","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1001\/archpsyc.61.10.974","volume":"61","author":"C McDonald","year":"2004","unstructured":"McDonald C, Bullmore ET, Sham PC, Chitnis X, Wickham H, Bramon E, Murray RM (2004) Association of genetic risks for schizophrenia and bipolar disorder with specific and generic brain structural endophenotypes. Arch Gen Psychiatry 61:974\u2013984","journal-title":"Arch Gen Psychiatry"},{"key":"1361_CR33","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1038\/s41398-018-0242-3","volume":"8","author":"M Markota","year":"2018","unstructured":"Markota M, Coombes BJ, Larrabee BR, McElroy SL, Bond DJ, Veldic M, Colby CL, Chauhan M, Cuellar-Barboza AB, Fuentes M, Kung S, Prieto ML, Rummans TA, Bobo WV, Frye MA, Biernacka JM (2018) Association of schizophrenia polygenic risk score with manic and depressive psychosis in bipolar disorder. Transl Psychiatry 8:188","journal-title":"Transl Psychiatry"},{"key":"1361_CR34","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1093\/schbul\/sbm028","volume":"33","author":"CU Correll","year":"2007","unstructured":"Correll CU, Penzner JB, Frederickson AM, Richter JJ, Auther AM, Smith CW, Kane JM, Cornblatt BA (2007) Differentiation in the preonset phases of schizophrenia and mood disorders: evidence in support of a bipolar mania prodrome. Schizophr Bull 33:703\u2013714","journal-title":"Schizophr Bull"},{"key":"1361_CR35","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1001\/jamapsychiatry.2017.3485","volume":"75","author":"J Allardyce","year":"2018","unstructured":"Allardyce J, Leonenko G, Hamshere M, Pardinas AF, Forty L, Knott S, Gordon-Smith K, Porteous DJ, Haywood C, Di Florio A, Jones L, McIntosh AM, Owen MJ, Holmans P, Walters JTR, Craddock N, Jones I, O\u2019Donovan MC, Escott-Price V (2018) Association between schizophrenia-related polygenic liability and the occurrence and level of mood-incongruent psychotic symptoms in bipolar disorder. JAMA Psychiat 75:28\u201335","journal-title":"JAMA Psychiat"},{"key":"1361_CR36","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1186\/s12888-016-0920-8","volume":"16","author":"Y Wei","year":"2016","unstructured":"Wei Y, Zhang T, Chow A, Tang Y, Xu L, Dai Y, Liu X, Su T, Pan X, Cui Y, Li Z, Jiang K, Xiao Z, Tang Y, Wang J (2016) Co-morbidity of personality disorder in schizophrenia among psychiatric outpatients in China: data from epidemiologic survey in a clinical population. BMC Psychiatry 16:224","journal-title":"BMC Psychiatry"},{"key":"1361_CR37","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1016\/j.schres.2006.12.023","volume":"91","author":"DL Fogelson","year":"2007","unstructured":"Fogelson DL, Nuechterlein KH, Asarnow RA, Payne DL, Subotnik KL, Jacobson KC, Neale MC, Kendler KS (2007) Avoidant personality disorder is a separable schizophrenia-spectrum personality disorder even when controlling for the presence of paranoid and schizotypal personality disorders. The UCLA family study. Schizophr Res 91:192\u2013199","journal-title":"Schizophr Res"},{"key":"1361_CR38","unstructured":"Cross-Disorder Group of the Psychiatric Genomics C, Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, Andreassen OA, Anjorin A, Anney R, Anttila V, Arking DE, Asherson P, Azevedo MH, Backlund L, Badner JA, Bailey AJ, Banaschewski T, Barchas JD, Barnes MR, Barrett TB, Bass N, Battaglia A, Bauer M, Bayes M, Bellivier F, Bergen SE, Berrettini W, Betancur C, Bettecken T, Biederman J, Binder EB, Black DW, Blackwood DH, Bloss CS, Boehnke M, Boomsma DI, Breen G, Breuer R, Bruggeman R, Cormican P, Buccola NG, Buitelaar JK, Bunney WE, Buxbaum JD, Byerley WF, Byrne EM, Caesar S, Cahn W, Cantor RM, Casas M, Chakravarti A, Chambert K, Choudhury K, Cichon S, Cloninger CR, Collier DA, Cook EH, Coon H, Cormand B, Corvin A, Coryell WH, Craig DW, Craig IW, Crosbie J, Cuccaro ML, Curtis D, Czamara D, Datta S, Dawson G, Day R, De Geus EJ, Degenhardt F, Djurovic S, Donohoe GJ, Doyle AE, Duan J, Dudbridge F, Duketis E, Ebstein RP, Edenberg HJ, Elia J, Ennis S, Etain B, Fanous A, Farmer AE, Ferrier IN, Flickinger M, Fombonne E, Foroud T, Frank J, Franke B, Fraser C, Freedman R, Freimer NB, Freitag CM, Friedl M, Frisen L, Gallagher L, Gejman PV, Georgieva L, Gershon ES, Geschwind DH, Giegling I, Gill M, Gordon SD, Gordon-Smith K, Green EK, Greenwood TA, Grice DE, Gross M, Grozeva D, Guan W, Gurling H, De Haan L, Haines JL, Hakonarson H, Hallmayer J, Hamilton SP, Hamshere ML, Hansen TF, Hartmann AM, Hautzinger M, Heath AC, Henders AK, Herms S, Hickie IB, Hipolito M, Hoefels S, Holmans PA, Holsboer F, Hoogendijk WJ, Hottenga JJ, Hultman CM, Hus V, Ingason A, Ising M, Jamain S, Jones EG, Jones I, Jones L, Tzeng JY, Kahler AK, Kahn RS, Kandaswamy R, Keller MC, Kennedy JL, Kenny E, Kent L, Kim Y, Kirov GK, Klauck SM, Klei L, Knowles JA, Kohli MA, Koller DL, Konte B, Korszun A, Krabbendam L, Krasucki R, Kuntsi J, Kwan P, Landen M, Langstrom N, Lathrop M, Lawrence J, Lawson WB, Leboyer M, Ledbetter DH, Lee PH, Lencz T, Lesch KP, Levinson DF, Lewis CM, Li J, Lichtenstein P, Lieberman JA, Lin DY, Linszen DH, Liu C, Lohoff FW, Loo SK, Lord C, Lowe JK, Lucae S, MacIntyre DJ, Madden PA, Maestrini E, Magnusson PK, Mahon PB, Maier W, Malhotra AK, Mane SM, Martin CL, Martin NG, Mattheisen M, Matthews K, Mattingsdal M, McCarroll SA, McGhee KA, McGough JJ, McGrath PJ, McGuffin P, McInnis MG, McIntosh A, McKinney R, McLean AW, McMahon FJ, McMahon WM, McQuillin A, Medeiros H, Medland SE, Meier S, Melle I, Meng F, Meyer J, Middeldorp CM, Middleton L, Milanova V, Miranda A, Monaco AP, Montgomery GW, Moran JL, Moreno-De-Luca D, Morken G, Morris DW, Morrow EM, Moskvina V, Muglia P, Muhleisen TW, Muir WJ, Muller-Myhsok B, Murtha M, Myers RM, Myin-Germeys I, Neale MC, Nelson SF, Nievergelt CM, Nikolov I, Nimgaonkar V, Nolen WA, Nothen MM, Nurnberger JI, Nwulia EA, Nyholt DR, O'Dushlaine C, Oades RD, Olincy A, Oliveira G, Olsen L, Ophoff RA, Osby U, Owen MJ, Palotie A, Parr JR, Paterson AD, Pato CN, Pato MT, Penninx BW, Pergadia ML, Pericak-Vance MA, Pickard BS, Pimm J, Piven J, Posthuma D, Potash JB, Poustka F, Propping P, Puri V, Quested DJ, Quinn EM, Ramos-Quiroga JA, Rasmussen HB, Raychaudhuri S, Rehnstrom K, Reif A, Ribases M, Rice JP, Rietschel M, Roeder K, Roeyers H, Rossin L, Rothenberger A, Rouleau G, Ruderfer D, Rujescu D, Sanders AR, Sanders SJ, Santangelo SL, Sergeant JA, Schachar R, Schalling M, Schatzberg AF, Scheftner WA, Schellenberg GD, Scherer SW, Schork NJ, Schulze TG, Schumacher J, Schwarz M, Scolnick E, Scott LJ, Shi J, Shilling PD, Shyn SI, Silverman JM, Slager SL, Smalley SL, Smit JH, Smith EN, Sonuga-Barke EJ, St Clair D, State M, Steffens M, Steinhausen HC, Strauss JS, Strohmaier J, Stroup TS, Sutcliffe JS, Szatmari P, Szelinger S, Thirumalai S, Thompson RC, Todorov AA, Tozzi F, Treutlein J, Uhr M, van den Oord EJ, Van Grootheest G, Van Os J, Vicente AM, Vieland VJ, Vincent JB, Visscher PM, Walsh CA, Wassink TH, Watson SJ, Weissman MM, Werge T, Wienker TF, Wijsman EM, Willemsen G, Williams N, Willsey AJ, Witt SH, Xu W, Young AH, Yu TW, Zammit S, Zandi PP, Zhang P, Zitman FG, Zollner S, Devlin B, Kelsoe JR, Sklar P, Daly MJ, O'Donovan MC, Craddock N, Sullivan PF, Smoller JW, Kendler KS, Wray NR, International Inflammatory Bowel Disease Genetics C. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet. 2013;45:984\u2013994."},{"key":"1361_CR39","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1001\/jamapsychiatry.2020.4799","volume":"78","author":"M Nourredine","year":"2021","unstructured":"Nourredine M, Gering A, Fourneret P, Rolland B, Falissard B, Cucherat M, Geoffray MM, Jurek L (2021) Association of attention-deficit\/hyperactivity disorder in childhood and adolescence with the risk of subsequent psychotic disorder: a systematic review and meta-analysis. JAMA Psychiat 78:519\u2013529","journal-title":"JAMA Psychiat"},{"key":"1361_CR40","doi-asserted-by":"publisher","first-page":"453","DOI":"10.3389\/fpsyt.2019.00453","volume":"10","author":"MJH Begemann","year":"2019","unstructured":"Begemann MJH, Linszen MMJ, de Boer JN, Hovenga WD, Gangadin SS, Schutte MJL, Sommer IEC (2019) Atopy increases risk of psychotic experiences: a large population-based study. Front Psychiatry 10:453","journal-title":"Front Psychiatry"},{"key":"1361_CR41","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1093\/schbul\/sbaa009","volume":"46","author":"YL Chen","year":"2020","unstructured":"Chen YL, Pan CH, Chang CK, Chen PH, Chang HM, Tai MH, Su SS, Tsai SY, Chen CC, Kuo CJ (2020) Physical illnesses before diagnosed as schizophrenia: a nationwide case\u2013control study. Schizophr Bull 46:785\u2013794","journal-title":"Schizophr Bull"},{"key":"1361_CR42","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1001\/jamapsychiatry.2015.0346","volume":"72","author":"E Agerbo","year":"2015","unstructured":"Agerbo E, Sullivan PF, Vilhjalmsson BJ, Pedersen CB, Mors O, Borglum AD, Hougaard DM, Hollegaard MV, Meier S, Mattheisen M, Ripke S, Wray NR, Mortensen PB (2015) Polygenic risk score, parental socioeconomic status, family history of psychiatric disorders, and the risk for schizophrenia: a Danish population-based study and meta-analysis. JAMA Psychiat 72:635\u2013641","journal-title":"JAMA Psychiat"},{"key":"1361_CR43","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/j.psychres.2009.08.003","volume":"179","author":"T Owashi","year":"2010","unstructured":"Owashi T, Ota A, Otsubo T, Susa Y, Kamijima K (2010) Obsessive-compulsive disorder and obsessive-compulsive symptoms in Japanese inpatients with chronic schizophrenia - a possible schizophrenic subtype. Psychiatry Res 179:241\u2013246","journal-title":"Psychiatry Res"},{"key":"1361_CR44","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1017\/S1092852916000390","volume":"22","author":"E Scotti-Muzzi","year":"2017","unstructured":"Scotti-Muzzi E, Saide OL (2017) Schizo-obsessive spectrum disorders: an update. CNS Spectr 22:258\u2013272","journal-title":"CNS Spectr"},{"key":"1361_CR45","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1093\/schbul\/sbx194","volume":"45","author":"YM Wang","year":"2019","unstructured":"Wang YM, Zou LQ, Xie WL, Yang ZY, Zhu XZ, Cheung EFC, Sorensen TA, Moller A, Chan RCK (2019) Altered functional connectivity of the default mode network in patients with Schizo-obsessive comorbidity: a comparison between schizophrenia and obsessive\u2013compulsive disorder. Schizophr Bull 45:199\u2013210","journal-title":"Schizophr Bull"},{"key":"1361_CR46","doi-asserted-by":"publisher","first-page":"560","DOI":"10.3389\/fnhum.2014.00560","volume":"8","author":"M Bleich-Cohen","year":"2014","unstructured":"Bleich-Cohen M, Poyurovsky M, Hendler T, Weizman R, Sharon H (2014) Does co-morbid obsessive\u2013compulsive disorder modify the abnormal language processing in schizophrenia patients? An FMRI study. Front Hum Neurosci 8:560","journal-title":"Front Hum Neurosci"},{"key":"1361_CR47","doi-asserted-by":"publisher","first-page":"1836","DOI":"10.1007\/s11682-016-9657-8","volume":"11","author":"C Hawco","year":"2017","unstructured":"Hawco C, Voineskos AN, Radhu N, Rotenberg D, Ameis S, Backhouse FA, Semeralul M, Daskalakis ZJ (2017) Age and gender interactions in white matter of schizophrenia and obsessive compulsive disorder compared to non-psychiatric controls: commonalities across disorders. Brain Imaging Behav 11:1836\u20131848","journal-title":"Brain Imaging Behav"},{"key":"1361_CR48","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1038\/tp.2016.34","volume":"6","author":"J Costas","year":"2016","unstructured":"Costas J, Carrera N, Alonso P, Gurriaran X, Segalas C, Real E, Lopez-Sola C, Mas S, Gasso P, Domenech L, Morell M, Quintela I, Lazaro L, Menchon JM, Estivill X, Carracedo A (2016) Exon-focused genome-wide association study of obsessive\u2013compulsive disorder and shared polygenic risk with schizophrenia. Transl Psychiatry 6:768","journal-title":"Transl Psychiatry"},{"key":"1361_CR49","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1186\/s13039-015-0144-5","volume":"8","author":"M Sakai","year":"2015","unstructured":"Sakai M, Watanabe Y, Someya T, Araki K, Shibuya M, Niizato K, Oshima K, Kunii Y, Yabe H, Matsumoto J, Wada A, Hino M, Hashimoto T, Hishimoto A, Kitamura N, Iritani S, Shirakawa O, Maeda K, Miyashita A, Niwa S, Takahashi H, Kakita A, Kuwano R, Nawa H (2015) Assessment of copy number variations in the brain genome of schizophrenia patients. Mol Cytogenet 8:46","journal-title":"Mol Cytogenet"},{"key":"1361_CR50","first-page":"100539","volume":"26","author":"L Mawn","year":"2020","unstructured":"Mawn L, Campbell T, Aynsworth C, Beckwith H, Luce A, Barclay N, Dodgson G, Freeston MH (2020) Comorbidity of obsessive-compulsive and psychotic experiences: a systematic review and meta-analysis. J Obs Compuls Relat Disord 26:100539","journal-title":"J Obs Compuls Relat Disord"},{"key":"1361_CR51","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1111\/acps.12258","volume":"130","author":"M Zink","year":"2014","unstructured":"Zink M, Schirmbeck F, Rausch F, Eifler S, Elkin H, Solojenkina X, Englisch S, Wagner M, Maier W, Lautenschlager M, Heinz A, Gudlowski Y, Janssen B, Gaebel W, Michel TM, Schneider F, Lambert M, Naber D, Juckel G, Krueger-Oezguerdal S, Wobrock T, Hasan A, Riedel M, Muller H, Klosterkotter J, Bechdolf A (2014) Obsessive\u2013compulsive symptoms in at-risk mental states for psychosis: associations with clinical impairment and cognitive function. Acta Psychiatr Scand 130:214\u2013226","journal-title":"Acta Psychiatr Scand"},{"key":"1361_CR52","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1007\/s00406-019-01022-z","volume":"270","author":"AR Rasmussen","year":"2020","unstructured":"Rasmussen AR, Nordgaard J, Parnas J (2020) Schizophrenia-spectrum psychopathology in obsessive-compulsive disorder: an empirical study. Eur Arch Psychiatry Clin Neurosci 270:993\u20131002","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"1361_CR53","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1007\/s11920-019-1051-y","volume":"21","author":"C Tezenas Montcel","year":"2019","unstructured":"Tezenas Montcel C, Pelissolo A, Schurhoff F, Pignon B (2019) Obsessive\u2013compulsive symptoms in schizophrenia: an up-to-date review of literature. Curr Psychiatry Rep 21:64","journal-title":"Curr Psychiatry Rep"}],"container-title":["European Archives of Psychiatry and Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00406-021-01361-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00406-021-01361-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00406-021-01361-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T10:04:19Z","timestamp":1681121059000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00406-021-01361-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,24]]},"references-count":53,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["1361"],"URL":"https:\/\/doi.org\/10.1007\/s00406-021-01361-w","relation":{},"ISSN":["0940-1334","1433-8491"],"issn-type":[{"value":"0940-1334","type":"print"},{"value":"1433-8491","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,24]]},"assertion":[{"value":"6 July 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 November 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 March 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"No conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}