{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:25:43Z","timestamp":1783643143322,"version":"3.55.0"},"reference-count":92,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,5,13]],"date-time":"2022-05-13T00:00:00Z","timestamp":1652400000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,5,13]],"date-time":"2022-05-13T00:00:00Z","timestamp":1652400000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Psychiatry Clin Neurosci"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>People with Alzheimer\u2019s disease (AD) and delusions have worse quality of life and prognosis. However, early markers of delusions have not been identified yet. The present study investigated whether there are any detectable differences in grey matter (GM) volume and cognitive changes in the year before symptom onset between patients with AD who did and did not develop delusions. Two matched samples of AD patients, 63 who did (PT-D) and 63 who did not develop delusions (PT-ND) over 1\u00a0year, were identified from the Alzheimer\u2019s Disease Neuroimaging Initiative database. The Neuropsychiatric Inventory (NPI) was used to assess the presence of delusions. Sixty-three additional matched healthy controls (HC) were selected. Repeated-measures ANCOVA models were used to investigate group-by-time effects on the volume of selected GM regions of interest and on cognitive performance. No neurocognitive differences were observed between patient groups prior to symptom onset. Greater episodic memory decline and GM loss in bilateral caudate nuclei, medio-temporal and midline cingulo-parietal regions were found in the PT-D compared with the PT-ND group. A pattern of faster GM loss in brain areas typically affected by AD and in cortical and subcortical targets of dopaminergic pathways, paralleled by worsening of episodic memory and behavioural symptoms, may explain the emergence of delusions in patients with AD.<\/jats:p>","DOI":"10.1007\/s00406-022-01417-5","type":"journal-article","created":{"date-parts":[[2022,5,13]],"date-time":"2022-05-13T09:06:06Z","timestamp":1652432766000},"page":"229-241","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Accelerated atrophy in dopaminergic targets and medial temporo-parietal regions precedes the onset of delusions in patients with Alzheimer\u2019s disease"],"prefix":"10.1007","volume":"273","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1715-6442","authenticated-orcid":false,"given":"Riccardo","family":"Manca","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Manuel","family":"Valera-Bermejo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9488-2301","authenticated-orcid":false,"given":"Annalena","family":"Venneri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the Alzheimer\u2019s Disease Neuroimaging Initiative","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,5,13]]},"reference":[{"key":"1417_CR1","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.2174\/1567205013666160502123129","volume":"13","author":"CA K\u00f6hler","year":"2016","unstructured":"K\u00f6hler CA, Magalhaes TF, Oliveira JM, Alves GS, Knochel C, Oertel-Kn\u00f6chel V, Pantel J, Carvalho AF (2016) Neuropsychiatric disturbances in mild cognitive impairment (mci): a systematic review of population-based studies. Curr Alzheimer Res 13:1066\u20131082","journal-title":"Curr Alzheimer Res"},{"key":"1417_CR2","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.1097\/JGP.0b013e3181d6b68d","volume":"18","author":"G Spalletta","year":"2010","unstructured":"Spalletta G, Musicco M, Padovani A, Rozzini L, Perri R, Fadda L, Canonico V, Trequattrini A, Pettenati C, Caltagirone C, Palmer K (2010) Neuropsychiatric symptoms and syndromes in a large cohort of newly diagnosed, untreated patients with alzheimer disease. Am J Geriatr Psychiatry 18:1026\u20131035","journal-title":"Am J Geriatr Psychiatry"},{"key":"1417_CR3","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.AD19038BR1C","author":"D Aarsland","year":"2020","unstructured":"Aarsland D (2020) Epidemiology and pathophysiology of dementia-related psychosis. J Clin Psychiatry. https:\/\/doi.org\/10.4088\/JCP.AD19038BR1C","journal-title":"J Clin Psychiatry"},{"key":"1417_CR4","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1192\/bjp.2019.195","volume":"216","author":"AO Vik-Mo","year":"2020","unstructured":"Vik-Mo AO, Giil LM, Borda MG, Ballard C, Aarsland D (2020) The individual course of neuropsychiatric symptoms in people with alzheimer\u2019s and lewy body dementia: 12-year longitudinal cohort study. Br J Psychiatry 216:43\u201348","journal-title":"Br J Psychiatry"},{"key":"1417_CR5","doi-asserted-by":"publisher","first-page":"427","DOI":"10.3233\/JAD-150944","volume":"51","author":"G D'Onofrio","year":"2016","unstructured":"D\u2019Onofrio G, Panza F, Sancarlo D, Paris FF, Cascavilla L, Mangiacotti A, Lauriola M, Paroni GH, Seripa D, Greco A (2016) Delusions in patients with alzheimer\u2019s disease: a multidimensional approach. J Alzheimers Dis 51:427\u2013437","journal-title":"J Alzheimers Dis"},{"key":"1417_CR6","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1136\/jnnp.69.2.172","volume":"69","author":"RS Wilson","year":"2000","unstructured":"Wilson RS, Gilley DW, Bennett DA, Beckett LA, Evans DA (2000) Hallucinations, delusions, and cognitive decline in alzheimer\u2019s disease. J Neurol Neurosurg Psychiatry 69:172\u2013177","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"1417_CR7","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/j.jagp.2017.10.011","volume":"26","author":"MH Connors","year":"2018","unstructured":"Connors MH, Ames D, Woodward M, Brodaty H (2018) Psychosis and clinical outcomes in alzheimer disease: a longitudinal study. Am J Geriatr Psychiatry 26:304\u2013313","journal-title":"Am J Geriatr Psychiatry"},{"key":"1417_CR8","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1159\/000339954","volume":"33","author":"CE Fischer","year":"2012","unstructured":"Fischer CE, Ismail Z, Schweizer TA (2012) Delusions increase functional impairment in alzheimer\u2019s disease. Dement Geriatr Cogn Disord 33:393\u2013399","journal-title":"Dement Geriatr Cogn Disord"},{"key":"1417_CR9","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1016\/j.biopsych.2013.08.020","volume":"75","author":"PS Murray","year":"2014","unstructured":"Murray PS, Kumar S, Demichele-Sweet MA, Sweet RA (2014) Psychosis in alzheimer\u2019s disease. Biol Psychiatry 75:542\u2013552","journal-title":"Biol Psychiatry"},{"key":"1417_CR10","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1002\/gps.4812","volume":"34","author":"L Lai","year":"2019","unstructured":"Lai L, Lee PE, Chan P, Fok MC, Hsiung GR, Sepehry AA (2019) Prevalence of delusions in drug-na\u00efve alzheimer disease patients: a meta-analysis. Int J Geriatr Psychiatry 34:1287\u20131293","journal-title":"Int J Geriatr Psychiatry"},{"key":"1417_CR11","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.3233\/JAD-190828","volume":"73","author":"CE Fischer","year":"2020","unstructured":"Fischer CE, Ismail Z, Youakim JM, Creese B, Kumar S, Nu\u00f1ez N, Ryan Darby R, Di Vita A, D\u2019Antonio F, de Lena C, McGeown WJ, Ramit R, Rasmussen J, Bell J, Wang H, Bruneau MA, Panegyres PK, Lanct\u00f4t KL, Ag\u00fcera-Ortiz L, Lyketsos C, Cummings J, Jeste DV, Sano M, Devanand DP, Sweet RA, Ballard C (2020) Revisiting criteria for psychosis in alzheimer\u2019s disease and related dementias: toward better phenotypic classification and biomarker research. J Alzheimers Dis 73:1143\u20131156","journal-title":"J Alzheimers Dis"},{"key":"1417_CR12","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1111\/j.1447-0594.2012.00897.x","volume":"13","author":"YT Kwak","year":"2013","unstructured":"Kwak YT, Yang Y, Kwak SG, Koo MS (2013) Delusions of korean patients with alzheimer\u2019s disease: study of drug-na\u00efve patients. Geriatr Gerontol Int 13:307\u2013313","journal-title":"Geriatr Gerontol Int"},{"key":"1417_CR13","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.1016\/j.jagp.2020.09.002","volume":"28","author":"J Cummings","year":"2020","unstructured":"Cummings J, Pinto LC, Cruz M, Fischer CE, Gerritsen DL, Grossberg GT, Hwang TJ, Ismail Z, Jeste DV, Koopmans R, Lanctot KL, Mateos R, Peschin S, Sampaio C, Tsuang D, Wang H, Zhong K, Bain LJ, Sano M (2020) Criteria for psychosis in major and mild neurocognitive disorders: International psychogeriatric association (ipa) consensus clinical and research definition. Am J Geriatr Psychiatry 28:1256\u20131269","journal-title":"Am J Geriatr Psychiatry"},{"key":"1417_CR14","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1111\/ggi.12105","volume":"14","author":"G Cipriani","year":"2014","unstructured":"Cipriani G, Danti S, Vedovello M, Nuti A, Lucetti C (2014) Understanding delusion in dementia: a review. Geriatr Gerontol Int 14:32\u201339","journal-title":"Geriatr Gerontol Int"},{"key":"1417_CR15","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-021-00597-3","author":"Z Ismail","year":"2022","unstructured":"Ismail Z, Creese B, Aarsland D, Kales HC, Lyketsos CG, Sweet RA, Ballard C (2022) Psychosis in alzheimer disease\u2014mechanisms, genetics and therapeutic opportunities. Nat Rev Neurol. https:\/\/doi.org\/10.1038\/s41582-021-00597-3","journal-title":"Nat Rev Neurol"},{"key":"1417_CR16","doi-asserted-by":"publisher","first-page":"283","DOI":"10.3233\/JAD-150606","volume":"50","author":"CE Fischer","year":"2016","unstructured":"Fischer CE, Qian W, Schweizer TA, Millikin CP, Ismail Z, Smith EE, Lix LM, Shelton P, Munoz DG (2016) Lewy bodies, vascular risk factors, and subcortical arteriosclerotic leukoencephalopathy, but not alzheimer pathology, are associated with development of psychosis in alzheimer\u2019s disease. J Alzheimers Dis 50:283\u2013295","journal-title":"J Alzheimers Dis"},{"key":"1417_CR17","doi-asserted-by":"publisher","first-page":"381","DOI":"10.3233\/JAD-160506","volume":"55","author":"J Kim","year":"2017","unstructured":"Kim J, Schweizer TA, Fischer CE, Munoz DG (2017) The role of cerebrovascular disease on cognitive and functional status and psychosis in severe alzheimer\u2019s disease. J Alzheimers Dis 55:381\u2013389","journal-title":"J Alzheimers Dis"},{"key":"1417_CR18","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1136\/jnnp-2018-318445","volume":"90","author":"AO Vik-Mo","year":"2019","unstructured":"Vik-Mo AO, Bencze J, Ballard C, Hortob\u00e1gyi T, Aarsland D (2019) Advanced cerebral amyloid angiopathy and small vessel disease are associated with psychosis in alzheimer\u2019s disease. J Neurol Neurosurg Psychiatry 90:728\u2013730","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"1417_CR19","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1159\/000335778","volume":"32","author":"S Palmqvist","year":"2011","unstructured":"Palmqvist S, Sarwari A, Wattmo C, Bronge L, Zhang Y, Wahlund LO, N\u00e4gga K (2011) Association between subcortical lesions and behavioral and psychological symptoms in patients with alzheimer\u2019s disease. Dement Geriatr Cogn Disord 32:417\u2013423","journal-title":"Dement Geriatr Cogn Disord"},{"key":"1417_CR20","doi-asserted-by":"publisher","first-page":"115","DOI":"10.3233\/JAD-180688","volume":"66","author":"AJ Ehrenberg","year":"2018","unstructured":"Ehrenberg AJ, Suemoto CK, Fran\u00e7a Resende EP, Petersen C, Leite REP, Rodriguez RD, Ferretti-Rebustini REL, You M, Oh J, Nitrini R, Pasqualucci CA, Jacob-Filho W, Kramer JH, Gatchel JR, Grinberg LT (2018) Neuropathologic correlates of psychiatric symptoms in alzheimer\u2019s disease. J Alzheimers Dis 66:115\u2013126","journal-title":"J Alzheimers Dis"},{"key":"1417_CR21","doi-asserted-by":"publisher","first-page":"2455","DOI":"10.1093\/brain\/awn151","volume":"131","author":"PD Bruen","year":"2008","unstructured":"Bruen PD, McGeown WJ, Shanks MF, Venneri A (2008) Neuroanatomical correlates of neuropsychiatric symptoms in alzheimer\u2019s disease. Brain 131:2455\u20132463","journal-title":"Brain"},{"key":"1417_CR22","doi-asserted-by":"publisher","first-page":"627","DOI":"10.3233\/JAD-2010-100048","volume":"21","author":"L Serra","year":"2010","unstructured":"Serra L, Perri R, Cercignani M, Span\u00f2 B, Fadda L, Marra C, Carlesimo GA, Caltagirone C, Bozzali M (2010) Are the behavioral symptoms of alzheimer\u2019s disease directly associated with neurodegeneration? J Alzheimers Dis 21:627\u2013639","journal-title":"J Alzheimers Dis"},{"key":"1417_CR23","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1017\/S1041610211000974","volume":"24","author":"D Whitehead","year":"2012","unstructured":"Whitehead D, Tunnard C, Hurt C, Wahlund LO, Mecocci P, Tsolaki M, Vellas B, Spenger C, K\u0142oszewska I, Soininen H, Cromb D, Lovestone S, Simmons A, Consortium A (2012) Frontotemporal atrophy associated with paranoid delusions in women with alzheimer\u2019s disease. Int psychogeriatrics 24:99\u2013107","journal-title":"Int psychogeriatrics"},{"key":"1417_CR24","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1093\/brain\/awaa058","volume":"143","author":"AM Tetreault","year":"2020","unstructured":"Tetreault AM, Phan T, Orlando D, Lyu I, Kang H, Landman B, Darby RR, AsDN I (2020) Network localization of clinical, cognitive, and neuropsychiatric symptoms in alzheimer\u2019s disease. Brain 143:1249\u20131260","journal-title":"Brain"},{"key":"1417_CR25","doi-asserted-by":"publisher","first-page":"1060","DOI":"10.1016\/j.jagp.2019.03.020","volume":"27","author":"W Qian","year":"2019","unstructured":"Qian W, Fischer CE, Churchill NW, Kumar S, Rajji T, Schweizer TA (2019) Delusions in alzheimer disease are associated with decreased default mode network functional connectivity. Am J Geriatr Psychiatry 27:1060\u20131068","journal-title":"Am J Geriatr Psychiatry"},{"key":"1417_CR26","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1002\/gps.4757","volume":"33","author":"E McLachlan","year":"2018","unstructured":"McLachlan E, Bousfield J, Howard R, Reeves S (2018) Reduced parahippocampal volume and psychosis symptoms in alzheimer\u2019s disease. Int J Geriatr Psychiatry 33:389\u2013395","journal-title":"Int J Geriatr Psychiatry"},{"key":"1417_CR27","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1159\/000089215","volume":"21","author":"S Nakano","year":"2006","unstructured":"Nakano S, Yamashita F, Matsuda H, Kodama C, Yamada T (2006) Relationship between delusions and regional cerebral blood flow in alzheimer\u2019s disease. Dement Geriatr Cogn Disord 21:16\u201321","journal-title":"Dement Geriatr Cogn Disord"},{"key":"1417_CR28","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1017\/S1041610213000094","volume":"25","author":"M Nakatsuka","year":"2013","unstructured":"Nakatsuka M, Meguro K, Tsuboi H, Nakamura K, Akanuma K, Yamaguchi S (2013) Content of delusional thoughts in alzheimer\u2019s disease and assessment of content-specific brain dysfunctions with behave-ad-fw and spect. Int Psychogeriatr 25:939\u2013948","journal-title":"Int Psychogeriatr"},{"key":"1417_CR29","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1111\/j.1479-8301.2012.00427.x","volume":"12","author":"K Nomura","year":"2012","unstructured":"Nomura K, Kazui H, Wada T, Sugiyama H, Yamamoto D, Yoshiyama K, Shimosegawa E, Hatazawa J, Takeda M (2012) Classification of delusions in alzheimer\u2019s disease and their neural correlates. Psychogeriatrics 12:200\u2013210","journal-title":"Psychogeriatrics"},{"key":"1417_CR30","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1080\/13546800244000021","volume":"7","author":"MF Shanks","year":"2002","unstructured":"Shanks MF, Venneri A (2002) The emergence of delusional companions in alzheimer\u2019s disease: an unusual misidentification syndrome. Cogn Neuropsychiatry 7:317\u2013328","journal-title":"Cogn Neuropsychiatry"},{"key":"1417_CR31","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1016\/S0010-9452(08)70818-9","volume":"35","author":"RT Staff","year":"1999","unstructured":"Staff RT, Shanks MF, Macintosh L, Pestell SJ, Gemmell HG, Venneri A (1999) Delusions in alzheimer\u2019s disease: spet evidence of right hemispheric dysfunction. Cortex 35:549\u2013560","journal-title":"Cortex"},{"key":"1417_CR32","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/S0028-3932(99)00061-5","volume":"38","author":"A Venneri","year":"2000","unstructured":"Venneri A, Shanks MF, Staff RT, Della Sala S (2000) Nurturing syndrome: a form of pathological bereavement with delusions in alzheimer\u2019s disease. Neuropsychologia 38:213\u2013214","journal-title":"Neuropsychologia"},{"key":"1417_CR33","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1136\/jnnp.69.2.167","volume":"69","author":"MS Mega","year":"2000","unstructured":"Mega MS, Lee L, Dinov ID, Mishkin F, Toga AW, Cummings JL (2000) Cerebral correlates of psychotic symptoms in alzheimer\u2019s disease. J Neurol Neurosurg Psychiatry 69:167\u2013171","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"1417_CR34","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1176\/jnp.13.1.50","volume":"13","author":"OL Lopez","year":"2001","unstructured":"Lopez OL, Smith G, Becker JT, Meltzer CC, DeKosky ST (2001) The psychotic phenomenon in probable alzheimer\u2019s disease: a positron emission tomography study. J Neuropsychiatry Clin Neurosci 13:50\u201355","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"1417_CR35","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1016\/0006-3223(94)00326-X","volume":"38","author":"MJ Mentis","year":"1995","unstructured":"Mentis MJ, Weinstein EA, Horwitz B, McIntosh AR, Pietrini P, Alexander GE, Furey M, Murphy DG (1995) Abnormal brain glucose metabolism in the delusional misidentification syndromes: a positron emission tomography study in alzheimer disease. Biol Psychiatry 38:438\u2013449","journal-title":"Biol Psychiatry"},{"key":"1417_CR36","doi-asserted-by":"publisher","first-page":"1346","DOI":"10.1016\/j.jagp.2013.06.005","volume":"22","author":"DL Sultzer","year":"2014","unstructured":"Sultzer DL, Leskin LP, Melrose RJ, Harwood DG, Narvaez TA, Ando TK, Mandelkern MA (2014) Neurobiology of delusions, memory, and insight in alzheimer disease. Am J Geriatr Psychiatry 22:1346\u20131355","journal-title":"Am J Geriatr Psychiatry"},{"key":"1417_CR37","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1212\/01.wnl.0000341932.21961.f3","volume":"72","author":"S Reeves","year":"2009","unstructured":"Reeves S, Brown R, Howard R, Grasby P (2009) Increased striatal dopamine (d2\/d3) receptor availability and delusions in alzheimer disease. Neurology 72:528\u2013534","journal-title":"Neurology"},{"key":"1417_CR38","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1016\/j.jagp.2012.10.028","volume":"22","author":"J Koppel","year":"2014","unstructured":"Koppel J, Sunday S, Goldberg TE, Davies P, Christen E, Greenwald BS, AsDN I (2014) Psychosis in alzheimer\u2019s disease is associated with frontal metabolic impairment and accelerated decline in working memory: findings from the alzheimer\u2019s disease neuroimaging initiative. Am J Geriatr Psychiatry 22:698\u2013707","journal-title":"Am J Geriatr Psychiatry"},{"key":"1417_CR39","first-page":"1","volume":"9","author":"S Nakaaki","year":"2013","unstructured":"Nakaaki S, Sato J, Torii K, Oka M, Negi A, Nakamae T, Narumoto J, Miyata J, Furukawa TA, Mimura M (2013) Neuroanatomical abnormalities before onset of delusions in patients with alzheimer\u2019s disease: a voxel-based morphometry study. Neuropsychiatr Dis Treat 9:1\u20138","journal-title":"Neuropsychiatr Dis Treat"},{"key":"1417_CR40","first-page":"25","volume":"9","author":"S Nakaaki","year":"2013","unstructured":"Nakaaki S, Sato J, Torii K, Oka M, Negi A, Nakamae T, Narumoto J, Miyata J, Furukawa TA, Mimura M (2013) Decreased white matter integrity before the onset of delusions in patients with alzheimer\u2019s disease: diffusion tensor imaging. Neuropsychiatr Dis Treat 9:25\u201329","journal-title":"Neuropsychiatr Dis Treat"},{"key":"1417_CR41","first-page":"70","volume":"6","author":"CJ Anor","year":"2021","unstructured":"Anor CJ, Dadar M, Collins DL, Tartaglia MC (2021) The longitudinal assessment of neuropsychiatric symptoms in mild cognitive impairment and alzheimer\u2019s disease and their association with white matter hyperintensities in the national alzheimer\u2019s coordinating center\u2019s uniform data set. Biol Psychiatry Cogn Neurosci Neuroimaging 6:70\u201378","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"key":"1417_CR42","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1002\/gps.4291","volume":"31","author":"CE Fischer","year":"2016","unstructured":"Fischer CE, Ting WK, Millikin CP, Ismail Z, Schweizer TA, Initiative ADN (2016) Gray matter atrophy in patients with mild cognitive impairment\/alzheimer\u2019s disease over the course of developing delusions. Int J Geriatr Psychiatry 31:76\u201382","journal-title":"Int J Geriatr Psychiatry"},{"key":"1417_CR43","doi-asserted-by":"publisher","first-page":"1689","DOI":"10.1002\/gps.5183","volume":"34","author":"F D'Antonio","year":"2019","unstructured":"D\u2019Antonio F, Di Vita A, Zazzaro G, Brus\u00e0 E, Trebbastoni A, Campanelli A, Ferracuti S, de Lena C, Guariglia C, Boccia M (2019) Psychosis of alzheimer\u2019s disease: neuropsychological and neuroimaging longitudinal study. Int J Geriatr Psychiatry 34:1689\u20131697","journal-title":"Int J Geriatr Psychiatry"},{"key":"1417_CR44","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1016\/j.jagp.2018.09.016","volume":"27","author":"W Qian","year":"2019","unstructured":"Qian W, Schweizer TA, Churchill NW, Millikin C, Ismail Z, Smith EE, Lix LM, Munoz DG, Barfett JJ, Rajji TK, Fischer CE (2019) Gray matter changes associated with the development of delusions in alzheimer disease. Am J Geriatr Psychiatry 27:490\u2013498","journal-title":"Am J Geriatr Psychiatry"},{"key":"1417_CR45","doi-asserted-by":"publisher","first-page":"1500","DOI":"10.1111\/ene.13076","volume":"23","author":"N Boublay","year":"2016","unstructured":"Boublay N, Schott AM, Krolak-Salmon P (2016) Neuroimaging correlates of neuropsychiatric symptoms in alzheimer\u2019s disease: a review of 20 years of research. Eur J Neurol 23:1500\u20131509","journal-title":"Eur J Neurol"},{"key":"1417_CR46","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.pscychresns.2012.01.008","volume":"202","author":"Z Ismail","year":"2012","unstructured":"Ismail Z, Nguyen MQ, Fischer CE, Schweizer TA, Mulsant BH (2012) Neuroimaging of delusions in alzheimer\u2019s disease. Psychiatry Res 202:89\u201395","journal-title":"Psychiatry Res"},{"key":"1417_CR47","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1007\/s11126-018-9588-1","volume":"89","author":"MV Seeman","year":"2018","unstructured":"Seeman MV (2018) Understanding the delusion of theft. Psychiatr Q 89:881\u2013889","journal-title":"Psychiatr Q"},{"key":"1417_CR48","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1590\/1516-4446-2016-1991","volume":"39","author":"FF de Oliveira","year":"2017","unstructured":"de Oliveira FF, Chen ES, Smith MC, Bertolucci PH (2017) Associations of cerebrovascular metabolism genotypes with neuropsychiatric symptoms and age at onset of alzheimer\u2019s disease dementia. Braz J Psychiatry 39:95\u2013103","journal-title":"Braz J Psychiatry"},{"key":"1417_CR49","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1038\/sj.npp.1301148","volume":"32","author":"KF Zdanys","year":"2007","unstructured":"Zdanys KF, Kleiman TG, MacAvoy MG, Black BT, Rightmer TE, Grey M, Garman KS, Tampi RR, Gelernter J, van Dyck CH (2007) Apolipoprotein e epsilon4 allele increases risk for psychotic symptoms in alzheimer\u2019s disease. Neuropsychopharmacology 32:171\u2013179","journal-title":"Neuropsychopharmacology"},{"key":"1417_CR50","doi-asserted-by":"publisher","first-page":"2022","DOI":"10.1176\/appi.ajp.162.11.2022","volume":"162","author":"SA Ropacki","year":"2005","unstructured":"Ropacki SA, Jeste DV (2005) Epidemiology of and risk factors for psychosis of alzheimer\u2019s disease: a review of 55 studies published from 1990 to 2003. Am J Psychiatry 162:2022\u20132030","journal-title":"Am J Psychiatry"},{"key":"1417_CR51","doi-asserted-by":"publisher","first-page":"S10","DOI":"10.1212\/WNL.48.5_Suppl_6.10S","volume":"48","author":"JL Cummings","year":"1997","unstructured":"Cummings JL (1997) The neuropsychiatric inventory: assessing psychopathology in dementia patients. Neurology 48:S10-16","journal-title":"Neurology"},{"key":"1417_CR52","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1176\/jnp.12.2.233","volume":"12","author":"DI Kaufer","year":"2000","unstructured":"Kaufer DI, Cummings JL, Ketchel P, Smith V, MacMillan A, Shelley T, Lopez OL, DeKosky ST (2000) Validation of the npi-q, a brief clinical form of the neuropsychiatric inventory. J Neuropsychiatry Clin Neurosci 12:233\u2013239","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"1417_CR53","doi-asserted-by":"publisher","first-page":"261","DOI":"10.3389\/fpsyg.2014.00261","volume":"5","author":"T Guadalupe","year":"2014","unstructured":"Guadalupe T, Willems RM, Zwiers MP, Arias Vasquez A, Hoogman M, Hagoort P, Fernandez G, Buitelaar J, Franke B, Fisher SE, Francks C (2014) Differences in cerebral cortical anatomy of left- and right-handers. Front Psychol 5:261","journal-title":"Front Psychol"},{"key":"1417_CR54","doi-asserted-by":"publisher","first-page":"e1564","DOI":"10.4088\/JCP.15m10617","volume":"77","author":"EA Weamer","year":"2016","unstructured":"Weamer EA, DeMichele-Sweet MA, Cloonan YK, Lopez OL, Sweet RA (2016) Incident psychosis in subjects with mild cognitive impairment or alzheimer\u2019s disease. J Clin Psychiatry 77:e1564\u2013e1569","journal-title":"J Clin Psychiatry"},{"key":"1417_CR55","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1016\/j.jalz.2018.02.018","volume":"14","author":"CR Jack Jr","year":"2018","unstructured":"Jack CR Jr, Bennett DA, Blennow K, Carrillo MC, Dunn B, Haeberlein SB, Holtzman DM, Jagust W, Jessen F, Karlawish J, Liu E, Molinuevo JL, Montine T, Phelps C, Rankin KP, Rowe CC, Scheltens P, Siemers E, Snyder HM, Sperling R (2018) Nia-aa research framework: toward a biological definition of alzheimer\u2019s disease. Alzheimers Dement 14:535\u2013562","journal-title":"Alzheimers Dement"},{"key":"1417_CR56","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1186\/2051-5960-1-65","volume":"1","author":"JB Toledo","year":"2013","unstructured":"Toledo JB, Cairns NJ, Da X, Chen K, Carter D, Fleisher A, Householder E, Ayutyanont N, Roontiva A, Bauer RJ, Eisen P, Shaw LM, Davatzikos C, Weiner MW, Reiman EM, Morris JC, Trojanowski JQ (2013) Clinical and multimodal biomarker correlates of adni neuropathological findings. Acta Neuropathol Commun 1:65","journal-title":"Acta Neuropathol Commun"},{"key":"1417_CR57","doi-asserted-by":"publisher","first-page":"1470","DOI":"10.1016\/j.jalz.2018.01.010","volume":"14","author":"O Hansson","year":"2018","unstructured":"Hansson O, Seibyl J, Stomrud E, Zetterberg H, Trojanowski JQ, Bittner T, Lifke V, Corradini V, Eichenlaub U, Batrla R, Buck K, Zink K, Rabe C, Blennow K, Shaw LM (2018) Csf biomarkers of alzheimer\u2019s disease concord with amyloid-\u03b2 pet and predict clinical progression: a study of fully automated immunoassays in biofinder and adni cohorts. Alzheimers Dement 14:1470\u20131481","journal-title":"Alzheimers Dement"},{"key":"1417_CR58","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1002\/jmri.21049","volume":"27","author":"CR Jack Jr","year":"2008","unstructured":"Jack CR Jr, Bernstein MA, Fox NC, Thompson P, Alexander G, Harvey D, Borowski B, Britson PJ, Whitwell JL, Ward C, Dale AM, Felmlee JP, Gunter JL, Hill DL, Killiany R, Schuff N, Fox-Bosetti S, Lin C, Studholme C, DeCarli CS, Krueger G, Ward HA, Metzger GJ, Scott KT, Mallozzi R, Blezek D, Levy J, Debbins JP, Fleisher AS, Albert M, Green R, Bartzokis G, Glover G, Mugler J, Weiner MW (2008) The alzheimer\u2019s disease neuroimaging initiative (adni): Mri methods. J Magn Reson Imaging 27:685\u2013691","journal-title":"J Magn Reson Imaging"},{"key":"1417_CR59","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1006\/nimg.2000.0582","volume":"11","author":"J Ashburner","year":"2000","unstructured":"Ashburner J, Friston KJ (2000) Voxel-based morphometry\u2013the methods. Neuroimage 11:805\u2013821","journal-title":"Neuroimage"},{"key":"1417_CR60","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.neuroimage.2015.07.075","volume":"122","author":"ET Rolls","year":"2015","unstructured":"Rolls ET, Joliot M, Tzourio-Mazoyer N (2015) Implementation of a new parcellation of the orbitofrontal cortex in the automated anatomical labeling atlas. Neuroimage 122:1\u20135","journal-title":"Neuroimage"},{"key":"1417_CR61","doi-asserted-by":"publisher","first-page":"167","DOI":"10.3233\/JAD-171018","volume":"63","author":"M De Marco","year":"2018","unstructured":"De Marco M, Venneri A (2018) Volume and connectivity of the ventral tegmental area are linked to neurocognitive signatures of alzheimer\u2019s disease in humans. J Alzheimers Dis 63:167\u2013180","journal-title":"J Alzheimers Dis"},{"key":"1417_CR62","doi-asserted-by":"publisher","first-page":"1233","DOI":"10.1016\/S1053-8119(03)00169-1","volume":"19","author":"JA Maldjian","year":"2003","unstructured":"Maldjian JA, Laurienti PJ, Kraft RA, Burdette JH (2003) An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fmri data sets. Neuroimage 19:1233\u20131239","journal-title":"Neuroimage"},{"key":"1417_CR63","doi-asserted-by":"publisher","first-page":"18707","DOI":"10.1038\/s41598-020-71368-1","volume":"10","author":"A Venneri","year":"2020","unstructured":"Venneri A, De Marco M (2020) Reduced monoaminergic nuclei mri signal detectable in pre-symptomatic older adults with future memory decline. Sci Rep 10:18707","journal-title":"Sci Rep"},{"key":"1417_CR64","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.neurobiolaging.2018.08.012","volume":"72","author":"L Serra","year":"2018","unstructured":"Serra L, D\u2019Amelio M, Di Domenico C, Dipasquale O, Marra C, Mercuri NB, Caltagirone C, Cercignani M, Bozzali M (2018) In vivo mapping of brainstem nuclei functional connectivity disruption in alzheimer\u2019s disease. Neurobiol Aging 72:72\u201382","journal-title":"Neurobiol Aging"},{"key":"1417_CR65","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1080\/00325481.2019.1663127","volume":"131","author":"E Capogna","year":"2019","unstructured":"Capogna E, Manca R, De Marco M, Hall A, Soininen H, Venneri A (2019) Understanding the effect of cognitive\/brain reserve and depression on regional atrophy in early alzheimer\u2019s disease. Postgrad Med 131:533\u2013538","journal-title":"Postgrad Med"},{"key":"1417_CR66","doi-asserted-by":"publisher","first-page":"1865","DOI":"10.1002\/hbm.22297","volume":"35","author":"A Marchewka","year":"2014","unstructured":"Marchewka A, Kherif F, Krueger G, Grabowska A, Frackowiak R, Draganski B, AsDN I (2014) Influence of magnetic field strength and image registration strategy on voxel-based morphometry in a study of alzheimer\u2019s disease. Hum Brain Mapp 35:1865\u20131874","journal-title":"Hum Brain Mapp"},{"key":"1417_CR67","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.nicl.2014.11.001","volume":"7","author":"D Schmitter","year":"2014","unstructured":"Schmitter D, Roche A, Mar\u00e9chal B, Ribes D, Abdulkadir A, Bach-Cuadra M, Daducci A, Granziera C, Kl\u00f6ppel S, Maeder P, Meuli R, Krueger G, AsDN I (2014) An evaluation of volume-based morphometry for prediction of mild cognitive impairment and alzheimer\u2019s disease. Neuroimage Clin 7:7\u201317","journal-title":"Neuroimage Clin"},{"key":"1417_CR68","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1192\/bjp.157.1.72","volume":"157","author":"A Burns","year":"1990","unstructured":"Burns A, Jacoby R, Levy R (1990) Psychiatric phenomena in alzheimer\u2019s disease. I: disorders of thought content. Br J Psychiatry 157:72\u201376","journal-title":"Br J Psychiatry"},{"key":"1417_CR69","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1176\/jnp.2008.20.1.62","volume":"20","author":"AM McMurtray","year":"2008","unstructured":"McMurtray AM, Sultzer DL, Monserratt L, Yeo T, Mendez MF (2008) Content-specific delusions from right caudate lacunar stroke: association with prefrontal hypometabolism. J Neuropsychiatry Clin Neurosci 20:62\u201367","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"1417_CR70","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1016\/j.ijge.2015.04.003","volume":"9","author":"Y Cheng","year":"2015","unstructured":"Cheng Y, Liu H (2015) Psychotic symptoms associated with left caudate infarction. Int J Gerontol 9:180\u2013182","journal-title":"Int J Gerontol"},{"key":"1417_CR71","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1111\/j.1479-8301.2011.00385.x","volume":"12","author":"K Meguro","year":"2012","unstructured":"Meguro K, Meguro M, Akanuma K (2012) Recurrent delusional ideas due to left caudate head infarction, without dementia. Psychogeriatrics 12:58\u201361","journal-title":"Psychogeriatrics"},{"key":"1417_CR72","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.biopsych.2016.03.2104","volume":"81","author":"JJ Weinstein","year":"2017","unstructured":"Weinstein JJ, Chohan MO, Slifstein M, Kegeles LS, Moore H, Abi-Dargham A (2017) Pathway-specific dopamine abnormalities in schizophrenia. Biol Psychiatry 81:31\u201342","journal-title":"Biol Psychiatry"},{"key":"1417_CR73","doi-asserted-by":"publisher","first-page":"5519","DOI":"10.1002\/hbm.23744","volume":"38","author":"F Caravaggio","year":"2017","unstructured":"Caravaggio F, Ku Chung J, Plitman E, Boileau I, Gerretsen P, Kim J, Iwata Y, Patel R, Chakravarty MM, Remington G, Graff-Guerrero A (2017) The relationship between subcortical brain volume and striatal dopamine d 2\/3 receptor availability in healthy humans assessed with [11 c]-raclopride and [11 c]-(+)-phno pet. Hum Brain Mapp 38:5519\u20135534","journal-title":"Hum Brain Mapp"},{"key":"1417_CR74","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.neuroimage.2009.01.049","volume":"46","author":"ND Woodward","year":"2009","unstructured":"Woodward ND, Zald DH, Ding Z, Riccardi P, Ansari MS, Baldwin RM, Cowan RL, Li R, Kessler RM (2009) Cerebral morphology and dopamine d2\/d3 receptor distribution in humans: a combined [18f] fallypride and voxel-based morphometry study. Neuroimage 46:31\u201338","journal-title":"Neuroimage"},{"key":"1417_CR75","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbab034","author":"L Smigielski","year":"2021","unstructured":"Smigielski L, Wotruba D, Treyer V, R\u00f6ssler J, Papiol S, Falkai P, Gr\u00fcnblatt E, Walitza S, R\u00f6ssler W (2021) The interplay between postsynaptic striatal d2\/3 receptor availability, adversity exposure and odd beliefs: a [11c]-raclopride pet study. Schizophr Bull. https:\/\/doi.org\/10.1093\/schbul\/sbab034","journal-title":"Schizophr Bull"},{"key":"1417_CR76","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.neuropsychologia.2018.04.030","volume":"123","author":"T M\u00fcller","year":"2019","unstructured":"M\u00fcller T, Apps MAJ (2019) Motivational fatigue: a neurocognitive framework for the impact of effortful exertion on subsequent motivation. Neuropsychologia 123:141\u2013151","journal-title":"Neuropsychologia"},{"key":"1417_CR77","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1038\/s41562-018-0440-2","volume":"2","author":"E Reutskaja","year":"2018","unstructured":"Reutskaja E, Lindner A, Nagel R, Andersen RA, Camerer CF (2018) Choice overload reduces neural signatures of choice set value in dorsal striatum and anterior cingulate cortex. Nat Hum Behav 2:925\u2013935","journal-title":"Nat Hum Behav"},{"key":"1417_CR78","doi-asserted-by":"publisher","first-page":"e113","DOI":"10.1016\/j.biopsych.2011.03.028","volume":"69","author":"R Cools","year":"2011","unstructured":"Cools R, D\u2019Esposito M (2011) Inverted-u-shaped dopamine actions on human working memory and cognitive control. Biol Psychiatry 69:e113\u2013e125","journal-title":"Biol Psychiatry"},{"key":"1417_CR79","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1093\/cercor\/bhz142","volume":"30","author":"G Papenberg","year":"2020","unstructured":"Papenberg G, Karalija N, Salami A, Rieckmann A, Andersson M, Axelsson J, Riklund K, Lindenberger U, L\u00f6vd\u00e9n M, Nyberg L, B\u00e4ckman L (2020) Balance between transmitter availability and dopamine d2 receptors in prefrontal cortex influences memory functioning. Cereb Cortex 30:989\u20131000","journal-title":"Cereb Cortex"},{"key":"1417_CR80","doi-asserted-by":"publisher","DOI":"10.1016\/j.concog.2020.102935","volume":"81","author":"MH Connors","year":"2020","unstructured":"Connors MH, Halligan PW (2020) Delusions and theories of belief. Conscious Cogn 81:102935","journal-title":"Conscious Cogn"},{"key":"1417_CR81","doi-asserted-by":"publisher","first-page":"E10167","DOI":"10.1073\/pnas.1809298115","volume":"115","author":"MM Nour","year":"2018","unstructured":"Nour MM, Dahoun T, Schwartenbeck P, Adams RA, FitzGerald THB, Coello C, Wall MB, Dolan RJ, Howes OD (2018) Dopaminergic basis for signaling belief updates, but not surprise, and the link to paranoia. Proc Natl Acad Sci USA 115:E10167\u2013E10176","journal-title":"Proc Natl Acad Sci USA"},{"key":"1417_CR82","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.tins.2018.12.004","volume":"42","author":"RA McCutcheon","year":"2019","unstructured":"McCutcheon RA, Abi-Dargham A, Howes OD (2019) Schizophrenia, dopamine and the striatum: from biology to symptoms. Trends Neurosci 42:205\u2013220","journal-title":"Trends Neurosci"},{"key":"1417_CR83","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1016\/S0306-4522(97)00534-4","volume":"84","author":"IJ Mitchell","year":"1998","unstructured":"Mitchell IJ, Cooper AJ, Griffiths MR, Barber DJ (1998) Phencyclidine and corticosteroids induce apoptosis of a subpopulation of striatal neurons: a neural substrate for psychosis? Neuroscience 84:498\u2013501","journal-title":"Neuroscience"},{"key":"1417_CR84","doi-asserted-by":"publisher","first-page":"2274","DOI":"10.1016\/j.neubiorev.2012.08.001","volume":"36","author":"SJ Reeves","year":"2012","unstructured":"Reeves SJ, Gould RL, Powell JF, Howard RJ (2012) Origins of delusions in alzheimer\u2019s disease. Neurosci Biobehav Rev 36:2274\u20132287","journal-title":"Neurosci Biobehav Rev"},{"key":"1417_CR85","doi-asserted-by":"publisher","first-page":"1584","DOI":"10.1002\/mds.27184","volume":"32","author":"K Kasanuki","year":"2017","unstructured":"Kasanuki K, Heckman MG, Diehl NN, Murray ME, Koga S, Soto A, Ross OA, Dickson DW (2017) Regional analysis and genetic association of nigrostriatal degeneration in lewy body disease. Mov Disord 32:1584\u20131593","journal-title":"Mov Disord"},{"key":"1417_CR86","doi-asserted-by":"publisher","first-page":"8683","DOI":"10.1073\/pnas.93.16.8683","volume":"93","author":"FA Middleton","year":"1996","unstructured":"Middleton FA, Strick PL (1996) The temporal lobe is a target of output from the basal ganglia. Proc Natl Acad Sci USA 93:8683\u20138687","journal-title":"Proc Natl Acad Sci USA"},{"key":"1417_CR87","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1196\/annals.1440.011","volume":"1124","author":"RL Buckner","year":"2008","unstructured":"Buckner RL, Andrews-Hanna JR, Schacter DL (2008) The brain\u2019s default network: anatomy, function, and relevance to disease. Ann NY Acad Sci 1124:1\u201338","journal-title":"Ann NY Acad Sci"},{"key":"1417_CR88","doi-asserted-by":"publisher","first-page":"294","DOI":"10.3758\/s13415-020-00769-6","volume":"20","author":"E Ambrosini","year":"2020","unstructured":"Ambrosini E, Capizzi M, Arbula S, Vallesi A (2020) Right-lateralized intrinsic brain dynamics predict monitoring abilities. Cogn Affect Behav Neurosci 20:294\u2013308","journal-title":"Cogn Affect Behav Neurosci"},{"key":"1417_CR89","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1002\/psp4.12389","volume":"8","author":"F D'Antonio","year":"2019","unstructured":"D\u2019Antonio F, Reeves S, Sheng Y, McLachlan E, de Lena C, Howard R, Bertrand J (2019) Misidentification subtype of alzheimer\u2019s disease psychosis predicts a faster cognitive decline. CPT Pharmacomet Syst Pharm 8:308\u2013315","journal-title":"CPT Pharmacomet Syst Pharm"},{"key":"1417_CR90","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1177\/1533317517703478","volume":"32","author":"J Cohen-Mansfield","year":"2017","unstructured":"Cohen-Mansfield J, Golander H, Cohen R (2017) Rethinking psychosis in dementia: an analysis of antecedents and explanations. Am J Alzheimers Dis Other Demen 32:265\u2013271","journal-title":"Am J Alzheimers Dis Other Demen"},{"key":"1417_CR91","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.cpr.2017.04.006","volume":"54","author":"A Broyd","year":"2017","unstructured":"Broyd A, Balzan RP, Woodward TS, Allen P (2017) Dopamine, cognitive biases and assessment of certainty: a neurocognitive model of delusions. Clin Psychol Rev 54:96\u2013106","journal-title":"Clin Psychol Rev"},{"key":"1417_CR92","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1080\/13546805.2014.990625","volume":"20","author":"PR Corlett","year":"2015","unstructured":"Corlett PR, Fletcher PC (2015) Delusions and prediction error: clarifying the roles of behavioural and brain responses. Cogn Neuropsychiatry 20:95\u2013105","journal-title":"Cogn Neuropsychiatry"}],"container-title":["European Archives of Psychiatry and Clinical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00406-022-01417-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00406-022-01417-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00406-022-01417-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,24]],"date-time":"2023-02-24T05:17:23Z","timestamp":1677215843000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00406-022-01417-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,13]]},"references-count":92,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["1417"],"URL":"https:\/\/doi.org\/10.1007\/s00406-022-01417-5","relation":{},"ISSN":["0940-1334","1433-8491"],"issn-type":[{"value":"0940-1334","type":"print"},{"value":"1433-8491","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,13]]},"assertion":[{"value":"5 November 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Institutional review boards of each site involved in ADNI approved the study protocol. Approval for secondary analyses of this dataset was granted by the Research Committee of Brunel University of London (reference number 30422-TISS-Jul\/2021-33453-2).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All participants provided written informed consent to take part in ADNI.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"All ADNI participants provided written informed consent to sharing their data with the scientific community that also includes publications.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}