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It has been hypothesized that the positive symptomatology of schizophrenia, and by extension, the odd beliefs and unusual perceptual experiences in the general population, are associated with specific alterations in memory functions. An imbalance between memory generalization and episodic memory specificity has been proposed on several counts; however, the direction of the imbalance is currently unclear. Here, we evaluated the association between positive schizotypy, and memory alterations related to hippocampal computations in a general population sample enriched for positive schizotypy. We found that memory generalization is attenuated while memory specificity is elevated in participants with more pronounced positive schizotypal traits. Our findings show that people who are prone to irrational beliefs and unusual experiences also show measurable alterations in memory and likely have difficulty grasping the global picture and rather be overpowered by fragments of information.<\/jats:p>","DOI":"10.1007\/s00406-022-01430-8","type":"journal-article","created":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T19:51:46Z","timestamp":1653681106000},"page":"447-458","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Positive schizotypy is associated with amplified mnemonic discrimination and attenuated generalization"],"prefix":"10.1007","volume":"273","author":[{"given":"\u00c1gota","family":"Vass","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melinda","family":"Becske","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1gnes","family":"Sz\u0151ll\u0151si","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mih\u00e1ly","family":"Racsm\u00e1ny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1789-9051","authenticated-orcid":false,"given":"Bertalan","family":"Polner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,5,27]]},"reference":[{"key":"1430_CR1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2014.00018","author":"U Ettinger","year":"2014","unstructured":"Ettinger U, Meyh\u00f6fer I, Steffens M et al (2014) Genetics, cognition, and neurobiology of schizotypal personality: a review of the overlap with schizophrenia. 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