{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T14:47:36Z","timestamp":1791989256870,"version":"4.4.0"},"reference-count":55,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur Arch Psychiatry Clin Neurosci"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Sexuality and intimacy are central dimensions of identity, emotional well-being, social connectedness, and quality of life. In individuals with schizophrenia spectrum disorders (SSDs), these domains may be profoundly affected by illness-related, psychological, interpersonal, social, institutional, and treatment-related factors. Although antipsychotic-induced sexual dysfunction is clinically relevant, a broader understanding of patients\u2019 subjective experiences is needed to capture the meaning of sexuality, intimacy, and relational well-being in this population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic review was conducted in accordance with the ENTREQ framework. PubMed, Scopus, and PsycINFO were searched to identify qualitative and mixed-methods studies exploring patients\u2019 subjective experiences of sexuality, sexual well-being, intimate relationships, and antipsychotic-induced sexual dysfunction in SSDs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Fifteen reports from 14 studies met the inclusion criteria. Thematic synthesis identified six overarching descriptive themes: (1) illness-related challenges to sexual well-being, (2) abuse and traumatic experiences, (3) beliefs about sexuality, (4) the role of the healthcare system, (5) barriers and facilitators of sexual well-being, and (6) antipsychotic-induced sexual side effects. Patients\u2019 accounts showed that sexuality was not limited to sexual functioning, but was closely connected to self-image, stigma, emotional closeness, relational opportunities, trauma, institutional restrictions, and communication with clinicians. The analytical synthesis indicated that these factors interacted through their effects on self-image, relational confidence, opportunities for intimacy, and sexual agency, potentially reinforcing vulnerability or supporting well-being and personal recovery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Sexual well-being in individuals with SSDs is shaped by medication-related, relational, psychological, and healthcare-related factors. These findings support the integration of sexuality into patient-centred psychiatric care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00406-026-02398-5","type":"journal-article","created":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T14:11:04Z","timestamp":1791987064000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Exploring sexuality, sexual well-being and intimacy in schizophrenia spectrum disorders: systematic review and meta-synthesis of qualitative studies"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-4923-9301","authenticated-orcid":false,"given":"Sofia Francesca","family":"Aprile","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Rodolico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Chiarenza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doris","family":"Cutrona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Munaf\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Salvina","family":"Signorelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Leucht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Caraci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,14]]},"reference":[{"key":"2398_CR1","doi-asserted-by":"publisher","first-page":"750","DOI":"10.2471\/BLT.23.291043","volume":"101","author":"M Narasimhan","year":"2023","unstructured":"Narasimhan M, Gilmore K, Murillo R, Allotey P (2023) Sexual health and well-being across the life course: call for papers. 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