{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T06:49:28Z","timestamp":1791874168789,"version":"4.3.4"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T00:00:00Z","timestamp":1538524800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lung"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1007\/s00408-018-0167-x","type":"journal-article","created":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T16:25:21Z","timestamp":1538583921000},"page":"761-767","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Objective and Subjective Sleep Efficiency in Adult Patients with Cystic Fibrosis and Impact on Quality of Life"],"prefix":"10.1007","volume":"196","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3470-7664","authenticated-orcid":false,"given":"Marta","family":"\u00cdscar-Urrutia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia Janeth","family":"Madrid-Carbajal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gemma","family":"Rubinos-Cuadrado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram\u00f3n","family":"Fern\u00e1ndez-\u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Jos\u00e9","family":"V\u00e1zquez-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Hern\u00e1ndez-Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Isabel","family":"Enr\u00edquez-Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Garc\u00eda-Clemente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,10,3]]},"reference":[{"key":"167_CR1","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1001\/archpedi.1938.01980140114013","volume":"56","author":"DH Andersen","year":"1938","unstructured":"Andersen DH (1938) Cystic fibrosis in the pancreas and its relationship to celiac disease. Am J Dis Child 56:344\u2013399","journal-title":"Am J Dis Child"},{"key":"167_CR2","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1126\/science.2570460","volume":"245","author":"B Kerem","year":"1989","unstructured":"Kerem B, Rommens JM, Buchanan JA, Markiewicz D, Cax TK, Chakravarti A et al (1989) Identification of the cystic fibrosis gene: genetic analysis. Science 245:1073\u20131080","journal-title":"Science"},{"issue":"4","key":"167_CR3","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1016\/j.jcf.2006.12.001","volume":"6","author":"C Verhaeghe","year":"2007","unstructured":"Verhaeghe C, Delbecque K, de Leval L, Oury C, Bours V (2007) Early inflammation in the airways of a cystic fibrosis foetus. J Cystic Fibros 6(4):304\u2013308","journal-title":"J Cystic Fibros"},{"key":"167_CR4","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1136\/thx.51.10.1023","volume":"51","author":"M Nir","year":"1996","unstructured":"Nir M, Lanng S, Johansen HK, Koch C (1996) Long term survival and nutritional data in patients with cystic fibrosis treated in Danish Centre. Thorax 51:1023\u20131027","journal-title":"Thorax"},{"key":"167_CR5","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1053\/rmed.2001.1194","volume":"95","author":"A Chetta","year":"2001","unstructured":"Chetta A, Pisi G, Zanini A, Foresi A, Grzincich GL, Aiello M et al (2001) Six minute walking test in cystic fibrosis adults with mild to moderate lung disease: comparison to healthy subjects. Respir Med 95:986\u2013991","journal-title":"Respir Med"},{"key":"167_CR6","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1016\/j.ccm.2014.06.005","volume":"35","author":"ES Katz","year":"2014","unstructured":"Katz ES (2014) Cystic fibrosis and sleep. Clin Chest Med 35:495\u2013504","journal-title":"Clin Chest Med"},{"key":"167_CR7","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1016\/j.jcf.2009.07.004","volume":"8","author":"PA Flume","year":"2009","unstructured":"Flume PA, Ciolino J, Gray S, Lester MK (2009) Patient-reported pain and impaired sleep quality in adult patients with cystic fibrosis. J Cystic Fibros 8:321\u2013325","journal-title":"J Cystic Fibros"},{"key":"167_CR8","doi-asserted-by":"publisher","first-page":"1593","DOI":"10.1378\/chest.127.5.1593","volume":"127","author":"L Jankelowitz","year":"2005","unstructured":"Jankelowitz L, Reid KJ, Wolfe L, Cullina J, Zee PC, Jain M (2005) Cystic fibrosis patients have poor sleep quality despite normal sleep latency and efficiency. Chest 127:1593\u20131599","journal-title":"Chest"},{"issue":"1","key":"167_CR9","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1007\/s11325-007-0123-0","volume":"12","author":"SK Naqvi","year":"2008","unstructured":"Naqvi SK, Sotelo C, Murry L, Simakajornboon N (2008) Sleep architecture in children and adolescents with cystic fibrosis and the association with severity of lung disease. Sleep Breath 12(1):77\u201383","journal-title":"Sleep Breath"},{"key":"167_CR10","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1183\/09031936.02.00088702","volume":"19","author":"DR Dancey","year":"2002","unstructured":"Dancey DR, Tullis ED, Heslegrave R, Thornley K, Hanly PJ (2002) Sleep quality and daytime function in adults with cystic fibrosis and severe lung disease. Eur Respir J 19:504\u2013510","journal-title":"Eur Respir J"},{"key":"167_CR11","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1136\/archdischild-2011-300440","volume":"97","author":"B Fauroux","year":"2012","unstructured":"Fauroux B, Pepin JL, Boelle PY, Cracowski C, Murris-Espin M, Nove-Josserand R et al (2012) Sleep quality and nocturnal hypoxemia and hypercapnia in children and young adults with cystic fibrosis. Arch Dis Child 97:960\u2013966","journal-title":"Arch Dis Child"},{"key":"167_CR12","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/j.jpainsymman.2007.06.005","volume":"35","author":"GS Sawicki","year":"2008","unstructured":"Sawicki GS, Sellers DE, Robinson WM (2008) Self-reported physical and psychological symptom burden in adults with cystic fibrosis. J Pain Symptom Manage 35:372\u2013380","journal-title":"J Pain Symptom Manage"},{"key":"167_CR13","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1183\/09031936.05.00034805","volume":"26","author":"MR Miller","year":"2005","unstructured":"Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi Rcoates A, et al (2005) Standardisation of spirometry. Eur Respir J 26:319\u2013338","journal-title":"Eur Respir J"},{"key":"167_CR14","doi-asserted-by":"publisher","first-page":"1324","DOI":"10.1183\/09031936.00080312","volume":"40","author":"Report ERS Task Force","year":"2012","unstructured":"Report ERS Task Force (2012) Multiethnic reference values for spirometry for the age range of 3 to 95 years: global lung function 2012 equations. Eur Respir J 40:1324\u20131343","journal-title":"Eur Respir J"},{"key":"167_CR15","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1183\/09031936.05.00035205","volume":"26","author":"R Pellegrino","year":"2005","unstructured":"Pellegrino R, Viegi G, Enright P, Brusasco V, Crapo RO, Burgos F et al (2005) Interpretative strategies for lung function tests. Eur Respir J 26:948\u2013968","journal-title":"Eur Respir J"},{"key":"167_CR16","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1164\/rccm.167.2.211","volume":"167","author":"American Thoracic Society","year":"2003","unstructured":"American Thoracic Society (2003) ATS\/ACCP statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med 167:211\u2013277","journal-title":"Am J Respir Crit Care Med"},{"key":"167_CR17","first-page":"165","volume":"46","author":"G Oliveira","year":"2010","unstructured":"Oliveira G, Gaspar I, Cruz I, Dorado A, P\u00e9rez- Ruiz E et al (2010) Validation of the Spanish version of the revised cystic fibrosis quality of life questionnaire in adolescents and adults (CFQR 14 + Spain). Arch Bronconeumol 46:165\u2013175","journal-title":"Arch Bronconeumol"},{"issue":"suppl","key":"167_CR18","first-page":"392","volume":"17","author":"B Henry","year":"1998","unstructured":"Henry B, Staab D, Prados C, Aussge P, de Ponth-Brune S, Grosskotf C et al (1998) How to measure quality of life in cystic fibrosis (CF) patients across countries and cultures: the Cystic Fibrosis Questionnaire (CFQ) abtrac. Pediatr Pulmonol 17(suppl):392\u2013393","journal-title":"Pediatr Pulmonol"},{"key":"167_CR19","doi-asserted-by":"publisher","first-page":"2347","DOI":"10.1378\/chest.128.4.2347","volume":"128","author":"AL Quittner","year":"2005","unstructured":"Quittner AL, Buu A, Messer MA, Modi AC, Watrous M (2005) Development and validation of the cystic Fibrosis Questionnaire in The United States: a health-related quality of life measure for cystic fibrosis. Chest 128:2347\u20132354","journal-title":"Chest"},{"key":"167_CR20","first-page":"81","volume":"9","author":"A Rayuela","year":"1997","unstructured":"Rayuela A, Mac\u00edas JA (1997) Propiedades clinim\u00e9tricas de la versi\u00f3n castellana del cuestionario Pittsburg. Vigilia-Sueno 9:81\u201394","journal-title":"Vigilia-Sueno"},{"key":"167_CR21","first-page":"143","volume":"47","author":"P Lloberes","year":"2011","unstructured":"Lloberes P, Duran Cantolla J, Mart\u00ednez\u2013Garc\u00eda MA, Mar\u00edn JM, Ferrer A, Corral J et al (2011) Diagn\u00f3stico y tratamiento del s\u00edndrome de apneas-hipopneas del sue\u00f1o. [Diagnosis and treatment of sleep apnea-hypopnea syndrome.]. Arch Bronconeumol 47:143\u2013156","journal-title":"Arch Bronconeumol"},{"key":"167_CR22","doi-asserted-by":"crossref","first-page":"597","DOI":"10.5664\/jcsm.2172","volume":"8","author":"RB Berry","year":"2012","unstructured":"Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK et al (2012) Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the scoring of sleep associated events. Deliberations of the sleep apnea definitions task force of the American academy of sleep medicine. J Clin Sleep Med 8:597\u2013619","journal-title":"J Clin Sleep Med"},{"key":"167_CR23","doi-asserted-by":"publisher","first-page":"1041","DOI":"10.1007\/s11325-011-0599-5","volume":"16","author":"C Perin","year":"2012","unstructured":"Perin C, Fagondes SC, Casarotto FC et al (2012) Sleep findings and predictors of sleep desaturation in adult cystic fibrosis patients. Sleep Breath 16:1041\u20131048","journal-title":"Sleep Breath"},{"key":"167_CR24","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1136\/adc.84.1.50","volume":"84","author":"MP Villa","year":"2001","unstructured":"Villa MP, Pagani J, Lucidi V, Palamides S, Ronchetti R (2001) Nocturnal oximetry in infants with cystic fibrosis. Arch Dis Child 84:50\u201354","journal-title":"Arch Dis Child"},{"key":"167_CR25","first-page":"3","volume-title":"Breathing disorders in sleep","author":"MJ Morrell","year":"2002","unstructured":"Morrell MJ, Dempsey JA (2002) Impact of Sleep on ventilation. In: McNicholas WT, Phillipson EA (eds) Breathing disorders in sleep. WB Saunders, London, pp\u00a03\u201317"},{"key":"167_CR26","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1164\/arrd.1980.121.3.463","volume":"121","author":"NL Muller","year":"1980","unstructured":"Muller NL, Francias PW, Gurwitz D, Levison H, Bryan AL (1980) Mechanism of hemoglobin desaturation during rapid eye movement sleep in normal subjects and in patients with cystic fibrosis. Am Rev Respir Dis 121:463\u2013469","journal-title":"Am Rev Respir Dis"},{"key":"167_CR27","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1164\/arrd.1984.129.5.712","volume":"129","author":"S Spier","year":"1984","unstructured":"Spier S, Rivlin J, Hughes D, Levison H (1984) The effect of oxygen on sleep, blood gases and ventilation in cystic fibrosis. Am Rev Respir Dis 129:712\u2013718","journal-title":"Am Rev Respir Dis"},{"key":"167_CR28","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/S0022-3476(89)80553-0","volume":"114","author":"R Zinmam","year":"1989","unstructured":"Zinmam R, Cory M, Coates AL et al (1989) Nocturnal Home oxygen in the treatment of hypoxemic cystic fibrosis patients. J Pediatr 114:368\u2013377","journal-title":"J Pediatr"},{"key":"167_CR29","first-page":"741","volume":"134","author":"DC Stokes","year":"1980","unstructured":"Stokes DC, McBride JT, Wall MA, Erba G, Strieder DJ (1980) Sleep Hypoxemia in young adults with cystic fibrosis. Am J Dis Child 134:741\u2013743","journal-title":"Am J Dis Child"},{"key":"167_CR30","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1378\/chest.120.4.1239","volume":"120","author":"MA Milross","year":"2001","unstructured":"Milross MA, Piper AJ, Norman M, Willson GN, Grunstein RR, Sullivan CE, Bye PT (2001) Predicting sleep-disordered breathing with cystic fibrosis. Chest 120:1239\u20131245","journal-title":"Chest"},{"key":"167_CR31","doi-asserted-by":"publisher","first-page":"1780","DOI":"10.1016\/j.ijporl.2009.09.037","volume":"73","author":"RT Ramos","year":"2009","unstructured":"Ramos RT, Salles C, Gregorio PB, Barros AT, Santana A, Araujo Filho-JB, Acosta AX (2009) Evaluation of the upper airway in children and adolescents with cystic fibrosis and obstructive sleep apnea syndrome. Int J Pediatr Otorhinolaryngol 73:1780\u20131785","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"167_CR32","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1378\/chest.100.3.659","volume":"100","author":"MJ Coffey","year":"1991","unstructured":"Coffey MJ, Fitzgerald MX, Mc Nicholas WT (1991) Comparison of oxygen desaturation during sleep and exercise in patients with cystic fibrosis. Chest 100:659\u2013662","journal-title":"Chest"},{"key":"167_CR33","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1378\/chest.116.3.647","volume":"116","author":"S Bradley","year":"1999","unstructured":"Bradley S, Salin P, Wilson J, Johns D, Walters EH, Naughton MT (1999) Hypoxemia and hypercapnia during exercise and sleep in patients with cystic fibrosis. Chest 116:647","journal-title":"Chest"}],"container-title":["Lung"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00408-018-0167-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00408-018-0167-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00408-018-0167-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T23:47:44Z","timestamp":1605138464000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00408-018-0167-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,3]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["167"],"URL":"https:\/\/doi.org\/10.1007\/s00408-018-0167-x","relation":{},"ISSN":["0341-2040","1432-1750"],"issn-type":[{"value":"0341-2040","type":"print"},{"value":"1432-1750","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,3]]},"assertion":[{"value":"20 March 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 September 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 October 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}