{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:22:03Z","timestamp":1786980123773,"version":"build-2736575974"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Lung"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1007\/s00408-021-00462-6","type":"journal-article","created":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T01:02:31Z","timestamp":1628557351000},"page":"409-416","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Influence of Obstructive Sleep Apnoea Severity on Coronary Collateral Recruitment During Coronary Occlusion"],"prefix":"10.1007","volume":"199","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7178-4744","authenticated-orcid":false,"given":"Usaid K.","family":"Allahwala","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7920-4924","authenticated-orcid":false,"given":"Peter A.","family":"Cistulli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasthi U.","family":"Dissanayake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Ward","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James C.","family":"Weaver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravinay","family":"Bhindi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,8,10]]},"reference":[{"key":"462_CR1","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.thromres.2019.03.004","volume":"177","author":"UK Allahwala","year":"2019","unstructured":"Allahwala UK, Weaver J, Bhindi R (2019) Animal chronic total occlusion models: a review of the current literature and future goals. Thromb Res 177:83\u201390. https:\/\/doi.org\/10.1016\/j.thromres.2019.03.004","journal-title":"Thromb Res"},{"key":"462_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mvr.2020.104058","author":"UK Allahwala","year":"2020","unstructured":"Allahwala UK, Khachigian LM, Nour D et al (2020) Recruitment and maturation of the coronary collateral circulation: current understanding and perspectives in arteriogenesis. Microvasc Res. https:\/\/doi.org\/10.1016\/j.mvr.2020.104058","journal-title":"Microvasc Res"},{"key":"462_CR3","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2147\/NSS.S124657","volume":"10","author":"AM Osman","year":"2018","unstructured":"Osman AM, Carter SG, Carberry JC et al (2018) Obstructive sleep apnea: current perspectives. Nat Sci Sleep 10:21\u201334. https:\/\/doi.org\/10.2147\/NSS.S124657","journal-title":"Nat Sci Sleep"},{"key":"462_CR4","doi-asserted-by":"publisher","first-page":"1829","DOI":"10.1001\/jama.283.14.1829","volume":"283","author":"FJ Nieto","year":"2000","unstructured":"Nieto FJ, Young TB, Lind BK et al (2000) Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health Study. JAMA 283:1829\u20131836. https:\/\/doi.org\/10.1001\/jama.283.14.1829","journal-title":"JAMA"},{"key":"462_CR5","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1378\/chest.11-3124","volume":"143","author":"FN Jilwan","year":"2013","unstructured":"Jilwan FN, Escourrou P, Garcia G et al (2013) High occurrence of hypoxemic sleep respiratory disorders in precapillary pulmonary hypertension and mechanisms. Chest 143:47\u201355. https:\/\/doi.org\/10.1378\/chest.11-3124","journal-title":"Chest"},{"key":"462_CR6","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.ejheart.2006.08.003","volume":"9","author":"O Oldenburg","year":"2007","unstructured":"Oldenburg O, Lamp B, Faber L et al (2007) Sleep-disordered breathing in patients with symptomatic heart failure: a contemporary study of prevalence in and characteristics of 700 patients. Eur J Heart Fail 9:251\u2013257. https:\/\/doi.org\/10.1016\/j.ejheart.2006.08.003","journal-title":"Eur J Heart Fail"},{"key":"462_CR7","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1378\/chest.11-0975","volume":"141","author":"FN Albuquerque","year":"2012","unstructured":"Albuquerque FN, Calvin AD, Sert Kuniyoshi FH et al (2012) Sleep-disordered breathing and excessive daytime sleepiness in patients with atrial fibrillation. Chest 141:967\u2013973. https:\/\/doi.org\/10.1378\/chest.11-0975","journal-title":"Chest"},{"key":"462_CR8","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.12828","volume":"28","author":"A Bikov","year":"2019","unstructured":"Bikov A, Kolossvary M, Jermendy AL et al (2019) Comprehensive coronary plaque assessment in patients with obstructive sleep apnea. J Sleep Res 28:e12828. https:\/\/doi.org\/10.1111\/jsr.12828","journal-title":"J Sleep Res"},{"key":"462_CR9","doi-asserted-by":"publisher","first-page":"1455","DOI":"10.1016\/j.amjcard.2020.02.023","volume":"125","author":"UK Allahwala","year":"2020","unstructured":"Allahwala UK, Weaver JC, Nelson GI et al (2020) Effect of recruitment of acute coronary collaterals on in-hospital mortality and on left ventricular function in patients presenting with ST elevation myocardial infarction. Am J Cardiol 125:1455\u20131460. https:\/\/doi.org\/10.1016\/j.amjcard.2020.02.023","journal-title":"Am J Cardiol"},{"key":"462_CR10","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-020-02282-6","author":"UK Allahwala","year":"2020","unstructured":"Allahwala UK, Nour D, Alsanjari O et al (2020) Prognostic implications of the rapid recruitment of coronary collaterals during ST elevation myocardial infarction (STEMI): a meta-analysis of over 14,000 patients. J Thromb Thrombolysis. https:\/\/doi.org\/10.1007\/s11239-020-02282-6","journal-title":"J Thromb Thrombolysis"},{"key":"462_CR11","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1536\/ihj.19-456","volume":"61","author":"UK Allahwala","year":"2020","unstructured":"Allahwala UK, Kott K, Bland A et al (2020) Predictors and prognostic implications of well-matured coronary collateral circulation in patients with a chronic total occlusion (CTO). Int Heart J 61:223\u2013230. https:\/\/doi.org\/10.1536\/ihj.19-456","journal-title":"Int Heart J"},{"key":"462_CR12","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29348","author":"UK Allahwala","year":"2020","unstructured":"Allahwala UK, Nour D, Bhatia K et al (2020) Prognostic impact of collaterals in patients with a coronary chronic total occlusion: a meta-analysis of over 3,000 patients. Catheter Cardiovasc Interv. https:\/\/doi.org\/10.1002\/ccd.29348","journal-title":"Catheter Cardiovasc Interv"},{"key":"462_CR13","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.amjcard.2021.02.034","volume":"148","author":"UK Allahwala","year":"2021","unstructured":"Allahwala UK, Cistulli PA, Ekmejian A et al (2021) Relation of obstructive sleep apnea in patients with a coronary chronic total occlusion to coronary collaterals and mortality. Am J Cardiol 148:30\u201335. https:\/\/doi.org\/10.1016\/j.amjcard.2021.02.034","journal-title":"Am J Cardiol"},{"key":"462_CR14","doi-asserted-by":"publisher","unstructured":"Allahwala UK, Cistulli PA, Ciofani JL, et al (2021) Influence of obstructive sleep apnoea on outcomes in patients with ST elevation myocardial infarction (STEMI)\u2014the role of the coronary collateral circulation. Heart Lung Circ. https:\/\/doi.org\/10.1016\/j.hlc.2021.07.008","DOI":"10.1016\/j.hlc.2021.07.008"},{"key":"462_CR15","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.119.007813","volume":"12","author":"UK Allahwala","year":"2019","unstructured":"Allahwala UK, Brilakis ES, Byrne J et al (2019) Applicability and interpretation of coronary physiology in the setting of a chronic total occlusion. Circ Cardiovasc Interv 12:e007813. https:\/\/doi.org\/10.1161\/CIRCINTERVENTIONS.119.007813","journal-title":"Circ Cardiovasc Interv"},{"key":"462_CR16","volume-title":"A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects","author":"A Rechschaffen","year":"1968","unstructured":"Rechschaffen A, Kales A (1968) A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects. Brain Information Service\/Brain Research Institute, Los Angeles"},{"key":"462_CR17","volume-title":"The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications","author":"C Iber","year":"2007","unstructured":"Iber C, American Academy of Sleep Medicine (2007) The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications. American Academy of Sleep Medicine, Westchester"},{"key":"462_CR18","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1016\/s0735-1097(85)80380-6","volume":"5","author":"KP Rentrop","year":"1985","unstructured":"Rentrop KP, Cohen M, Blanke H et al (1985) Changes in collateral channel filling immediately after controlled coronary artery occlusion by an angioplasty balloon in human subjects. J Am Coll Cardiol 5:587\u2013592. https:\/\/doi.org\/10.1016\/s0735-1097(85)80380-6","journal-title":"J Am Coll Cardiol"},{"key":"462_CR19","doi-asserted-by":"publisher","first-page":"H1103","DOI":"10.1152\/ajpheart.1990.258.4.H1103","volume":"258","author":"WM Chilian","year":"1990","unstructured":"Chilian WM, Mass HJ, Williams SE et al (1990) Microvascular occlusions promote coronary collateral growth. Am J Physiol 258:H1103\u2013H1111. https:\/\/doi.org\/10.1152\/ajpheart.1990.258.4.H1103","journal-title":"Am J Physiol"},{"key":"462_CR20","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1007\/s00380-019-01493-z","volume":"35","author":"UK Allahwala","year":"2020","unstructured":"Allahwala UK, Weaver JC, Bhindi R (2020) Spontaneous coronary collateral recruitment in patients with recurrent ST elevation myocardial infarction (STEMI). Heart Vessels 35:291\u2013296. https:\/\/doi.org\/10.1007\/s00380-019-01493-z","journal-title":"Heart Vessels"},{"key":"462_CR21","doi-asserted-by":"publisher","first-page":"S393","DOI":"10.1016\/j.hlc.2019.06.603","volume":"28","author":"UK Allahwala","year":"2019","unstructured":"Allahwala UK, Ward M, Weaver J et al (2019) Correlation between coronary collaterals and systemic endothelial biomarkers: MCP-1 and ICAM-1 are associated with the coronary collateral circulation. Heart Lung Circ 28:S393","journal-title":"Heart Lung Circ"},{"key":"462_CR22","doi-asserted-by":"publisher","first-page":"1664","DOI":"10.1161\/01.ATV.0000138028.14390.e4","volume":"24","author":"F Pipp","year":"2004","unstructured":"Pipp F, Boehm S, Cai WJ et al (2004) Elevated fluid shear stress enhances postocclusive collateral artery growth and gene expression in the pig hind limb. Arterioscler Thromb Vasc Biol 24:1664\u20131668. https:\/\/doi.org\/10.1161\/01.ATV.0000138028.14390.e4","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"462_CR23","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1161\/01.RES.0000122041.73808.B5","volume":"94","author":"M Heil","year":"2004","unstructured":"Heil M, Ziegelhoeffer T, Wagner S et al (2004) Collateral artery growth (arteriogenesis) after experimental arterial occlusion is impaired in mice lacking CC-chemokine receptor-2. Circ Res 94:671\u2013677. https:\/\/doi.org\/10.1161\/01.RES.0000122041.73808.B5","journal-title":"Circ Res"},{"key":"462_CR24","doi-asserted-by":"publisher","first-page":"1940","DOI":"10.1161\/01.CIR.0000143624.72027.11","volume":"110","author":"GS Werner","year":"2004","unstructured":"Werner GS, Jandt E, Krack A et al (2004) Growth factors in the collateral circulation of chronic total coronary occlusions: relation to duration of occlusion and collateral function. Circulation 110:1940\u20131945. https:\/\/doi.org\/10.1161\/01.CIR.0000143624.72027.11","journal-title":"Circulation"},{"key":"462_CR25","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.ancard.2015.01.014","volume":"64","author":"H Ben Ahmed","year":"2015","unstructured":"Ben Ahmed H, Boussaid H, Longo S et al (2015) Impact of obstructive sleep apnea in recruitment of coronary collaterality during inaugural acute myocardial infarction. Ann Cardiol Angeiol (Paris) 64:273\u2013278. https:\/\/doi.org\/10.1016\/j.ancard.2015.01.014","journal-title":"Ann Cardiol Angeiol (Paris)"},{"key":"462_CR26","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1378\/chest.09-1136","volume":"137","author":"S Steiner","year":"2010","unstructured":"Steiner S, Schueller PO, Schulze V et al (2010) Occurrence of coronary collateral vessels in patients with sleep apnea and total coronary occlusion. Chest 137:516\u2013520. https:\/\/doi.org\/10.1378\/chest.09-1136","journal-title":"Chest"},{"key":"462_CR27","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1093\/sleep\/31.6.809","volume":"31","author":"GS Hamilton","year":"2008","unstructured":"Hamilton GS, Solin P, Walker A (2008) Coronary blood flow becomes uncoupled from myocardial work during obstructive sleep apnea in the presence of endothelial dysfunction. Sleep 31:809\u2013816. https:\/\/doi.org\/10.1093\/sleep\/31.6.809","journal-title":"Sleep"},{"key":"462_CR28","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1161\/HYPERTENSIONAHA.111.170910","volume":"58","author":"M Butt","year":"2011","unstructured":"Butt M, Khair OA, Dwivedi G et al (2011) Myocardial perfusion by myocardial contrast echocardiography and endothelial dysfunction in obstructive sleep apnea. Hypertension 58:417\u2013424. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.111.170910","journal-title":"Hypertension"},{"key":"462_CR29","doi-asserted-by":"publisher","first-page":"38","DOI":"10.2174\/1573403x113099990005","volume":"10","author":"M Stoller","year":"2014","unstructured":"Stoller M, Seiler C (2014) Pathophysiology of coronary collaterals. Curr Cardiol Rev 10:38\u201356. https:\/\/doi.org\/10.2174\/1573403x113099990005","journal-title":"Curr Cardiol Rev"},{"key":"462_CR30","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0183836","volume":"12","author":"Z Liu","year":"2017","unstructured":"Liu Z, Pericak-Vance MA, Goldschmidt-Clermont P et al (2017) Coronary collateralization shows sex and racial-ethnic differences in obstructive artery disease patients. PLoS ONE 12:e0183836. https:\/\/doi.org\/10.1371\/journal.pone.0183836","journal-title":"PLoS ONE"},{"key":"462_CR31","doi-asserted-by":"publisher","first-page":"146","DOI":"10.5152\/akd.2012.250","volume":"13","author":"C Zorkun","year":"2013","unstructured":"Zorkun C, Akkaya E, Zorlu A et al (2013) Determinants of coronary collateral circulation in patients with coronary artery disease. Anadolu Kardiyol Derg 13:146\u2013151. https:\/\/doi.org\/10.5152\/akd.2012.250","journal-title":"Anadolu Kardiyol Derg"},{"key":"462_CR32","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1038\/79510","volume":"6","author":"Y Kureishi","year":"2000","unstructured":"Kureishi Y, Luo Z, Shiojima I et al (2000) The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nat Med 6:1004\u20131010. https:\/\/doi.org\/10.1038\/79510","journal-title":"Nat Med"},{"key":"462_CR33","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1136\/hrt.2003.017871","volume":"90","author":"S Zbinden","year":"2004","unstructured":"Zbinden S, Brunner N, Wustmann K et al (2004) Effect of statin treatment on coronary collateral flow in patients with coronary artery disease. Heart 90:448\u2013449. https:\/\/doi.org\/10.1136\/hrt.2003.017871","journal-title":"Heart"}],"container-title":["Lung"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00408-021-00462-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00408-021-00462-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00408-021-00462-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,3]],"date-time":"2021-09-03T14:19:05Z","timestamp":1630678745000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00408-021-00462-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["462"],"URL":"https:\/\/doi.org\/10.1007\/s00408-021-00462-6","relation":{},"ISSN":["0341-2040","1432-1750"],"issn-type":[{"value":"0341-2040","type":"print"},{"value":"1432-1750","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"7 June 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 July 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 August 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"UKA has received an unconditional research grant from Heart Research Australia. PAC holds an endowed academic Chairs at the University of Sydney, established through funding from ResMed. PAC has received research support from ResMed, SomnoMed, Zephyr Sleep Technologies and Bayer. He is a consultant\/adviser to Zephyr Sleep Technologies, ResMed and SomnoMed. He has a pecuniary interest in SomnoMed related to a previous role in R&D (2004). He has received speaker fees from Nox Medical and ResMed. RB has received an unconditional future leaders fellowship from the Heart Foundation.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}