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M.P. has no disclosures to report. P.O.B. reports grants and personal fees from AstraZeneca, personal fees from GSK, grants from Novartis, grants and personal fees from Medimmune, and personal fees from Chiesi, outside the submitted work. I.S. reports grants and personal fees from Merck Canada, grants and personal fees from GSK, and personal fees from AstraZeneca, Respiplus, and Genentech outside the submitted work. I.S. is currently supported by the E.J. Moran Campbell Early Career Award, Department of Medicine, McMaster University.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}