{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T22:58:13Z","timestamp":1783033093451,"version":"3.54.6"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2010,4,18]],"date-time":"2010-04-18T00:00:00Z","timestamp":1271548800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiat Environ Biophys"],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1007\/s00411-010-0287-z","type":"journal-article","created":{"date-parts":[[2010,4,17]],"date-time":"2010-04-17T13:54:02Z","timestamp":1271512442000},"page":"397-404","source":"Crossref","is-referenced-by-count":20,"title":["Single exposure to radiation produces early anti-angiogenic effects in mouse aorta"],"prefix":"10.1007","volume":"49","author":[{"given":"Kevin G.","family":"Soucy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David O.","family":"Attarzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raghav","family":"Ramachandran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia A.","family":"Soucy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lewis H.","family":"Romer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Artin A.","family":"Shoukas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan E.","family":"Berkowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,4,18]]},"reference":[{"key":"287_CR1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0076-6879(08)02007-7","volume":"443","author":"AC Aplin","year":"2008","unstructured":"Aplin AC, Fogel E, Zorzi P, Nicosia RF (2008) The aortic ring model of angiogenesis. Methods Enzymol 443:119\u2013136","journal-title":"Methods Enzymol"},{"key":"287_CR2","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1126\/science.275.5302.964","volume":"275","author":"T Asahara","year":"1997","unstructured":"Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, Witzenbichler B, Schatteman G, Isner JM (1997) Isolation of putative progenitor endothelial cells for angiogenesis. Science 275:964\u2013967","journal-title":"Science"},{"key":"287_CR3","doi-asserted-by":"crossref","first-page":"64","DOI":"10.2307\/3579237","volume":"144","author":"M Benderitter","year":"1995","unstructured":"Benderitter M, Maingon P, Abadie C, Assem M, Maupoil V, Briot F, Horiot JC, Rochette L (1995) Effect of in vivo heart irradiation on the development of antioxidant defenses and cardiac functions in the rat. Radiat Res 144:64\u201372","journal-title":"Radiat Res"},{"key":"287_CR4","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1667\/0033-7587(2001)155[0353:REOHIP]2.0.CO;2","volume":"155","author":"A Brooks","year":"2001","unstructured":"Brooks A, Bao S, Rithidech K, Couch LA, Braby LA (2001) Relative effectiveness of hze iron-56 particles for the induction of cytogenetic damage in vivo. Radiat Res 155:353\u2013359","journal-title":"Radiat Res"},{"key":"287_CR5","doi-asserted-by":"crossref","first-page":"117","DOI":"10.2307\/3579020","volume":"142","author":"E Cardis","year":"1995","unstructured":"Cardis E, Gilbert ES, Carpenter L, Howe G, Kato I, Armstrong BK, Beral V, Cowper G, Douglas A, Fix J et al (1995) Effects of low doses and low dose rates of external ionizing radiation: cancer mortality among nuclear industry workers in three countries. Radiat Res 142:117\u2013132","journal-title":"Radiat Res"},{"key":"287_CR6","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1038\/nature04478","volume":"438","author":"P Carmeliet","year":"2005","unstructured":"Carmeliet P (2005) Angiogenesis in life, disease and medicine. Nature 438:932\u2013936","journal-title":"Nature"},{"key":"287_CR7","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S1470-2045(06)70695-7","volume":"7","author":"FA Cucinotta","year":"2006","unstructured":"Cucinotta FA, Durante M (2006) Cancer risk from exposure to galactic cosmic rays: implications for space exploration by human beings. Lancet Oncol 7:431\u2013435","journal-title":"Lancet Oncol"},{"key":"287_CR8","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1093\/jnci\/djp147","volume":"101","author":"ML Bruin De","year":"2009","unstructured":"De Bruin ML, Dorresteijn LD, van\u2019t Veer MB, Krol AD, van der Pal HJ, Kappelle AC, Boogerd W, Aleman BM, van Leeuwen FE (2009) Increased risk of stroke and transient ischemic attack in 5-year survivors of hodgkin lymphoma. J Natl Cancer Inst 101:928\u2013937","journal-title":"J Natl Cancer Inst"},{"key":"287_CR9","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0167-8140(02)00060-9","volume":"63","author":"JW Denham","year":"2002","unstructured":"Denham JW, Hauer-Jensen M (2002) The radiotherapeutic injury: a complex \u201cwound\u201d. Radiother Oncol 63:129\u2013145","journal-title":"Radiother Oncol"},{"key":"287_CR10","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0167-8140(99)00107-3","volume":"52","author":"JW Denham","year":"1999","unstructured":"Denham JW, Peters LJ, Johansen J, Poulsen M, Lamb DS, Hindley A, O\u2019Brien PC, Spry NA, Penniment M, Krawitz H, Williamson S, Bear J, Tripcony L (1999) Do acute mucosal reactions lead to consequential late reactions in patients with head and neck cancer? Radiother Oncol 52:157\u2013164","journal-title":"Radiother Oncol"},{"key":"287_CR11","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1006\/niox.1997.0133","volume":"1","author":"S Dimmeler","year":"1997","unstructured":"Dimmeler S, Zeiher AM (1997) Nitric oxide and apoptosis: another paradigm for the double-edged role of nitric oxide. Nitric Oxide 1:275\u2013281","journal-title":"Nitric Oxide"},{"key":"287_CR12","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1200\/JCO.2002.20.1.282","volume":"20","author":"LD Dorresteijn","year":"2002","unstructured":"Dorresteijn LD, Kappelle AC, Boogerd W, Klokman WJ, Balm AJ, Keus RB, van Leeuwen FE, Bartelink H (2002) Increased risk of ischemic stroke after radiotherapy on the neck in patients younger than 60\u00a0years. J Clin Oncol 20:282\u2013288","journal-title":"J Clin Oncol"},{"key":"287_CR13","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1016\/S0140-6736(00)02263-7","volume":"355","author":"EBCTCG","year":"2000","unstructured":"EBCTCG (2000) Favourable and unfavourable effects on long-term survival of radiotherapy for early breast cancer: an overview of the randomised trials. Early breast cancer trialists\u2019 collaborative group. Lancet 355:1757\u20131770","journal-title":"Lancet"},{"key":"287_CR14","doi-asserted-by":"crossref","first-page":"5711","DOI":"10.4049\/jimmunol.181.8.5711","volume":"181","author":"M Gelati","year":"2008","unstructured":"Gelati M, Aplin AC, Fogel E, Smith KD, Nicosia RF (2008) The angiogenic response of the aorta to injury and inflammatory cytokines requires macrophages. J Immunol 181:5711\u20135719","journal-title":"J Immunol"},{"key":"287_CR15","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1182\/blood.V92.3.765","volume":"92","author":"A Gratwohl","year":"1998","unstructured":"Gratwohl A, John L, Baldomero H, Roth J, Tichelli A, Nissen C, Lyman SD, Wodnar-Filipowicz A (1998) Flt-3 ligand provides hematopoietic protection from total body irradiation in rabbits. Blood 92:765\u2013769","journal-title":"Blood"},{"key":"287_CR16","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1001\/jama.1993.03510160067031","volume":"270","author":"SL Hancock","year":"1993","unstructured":"Hancock SL, Tucker MA, Hoppe RT (1993) Factors affecting late mortality from heart disease after treatment of hodgkin\u2019s disease. JAMA 270:1949\u20131955","journal-title":"JAMA"},{"key":"287_CR17","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.bbrc.2008.01.080","volume":"368","author":"F Hillen","year":"2008","unstructured":"Hillen F, Kaijzel EL, Castermans K, Oude Egbrink MG, Lowik CW, Griffioen AW (2008) A transgenic tie2-gfp athymic mouse model; a tool for vascular biology in xenograft tumors. Biochem Biophys Res Commun 368:364\u2013367","journal-title":"Biochem Biophys Res Commun"},{"key":"287_CR18","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/S0360-3016(01)01570-X","volume":"50","author":"M Kollum","year":"2001","unstructured":"Kollum M, Cottin Y, Chan RC, Kim HS, Bhargava B, Vodovotz Y, Waksman R (2001) Decreased adventitial neovascularization after intracoronary irradiation in swine: a time course study. Int J Radiat Oncol Biol Phys 50:1033\u20131039","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"287_CR19","doi-asserted-by":"crossref","first-page":"118","DOI":"10.2307\/3576889","volume":"110","author":"S Lauk","year":"1987","unstructured":"Lauk S (1987) Endothelial alkaline phosphatase activity loss as an early stage in the development of radiation-induced heart disease in rats. Radiat Res 110:118\u2013128","journal-title":"Radiat Res"},{"key":"287_CR20","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/0360-3016(85)90314-1","volume":"11","author":"S Lauk","year":"1985","unstructured":"Lauk S, Kiszel Z, Buschmann J, Trott KR (1985) Radiation-induced heart disease in rats. Int J Radiat Oncol Biol Phys 11:801\u2013808","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"287_CR21","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/jemt.10249","volume":"60","author":"J Li","year":"2003","unstructured":"Li J, Zhang YP, Kirsner RS (2003) Angiogenesis in wound repair: angiogenic growth factors and the extracellular matrix. Microsc Res Tech 60:107\u2013114","journal-title":"Microsc Res Tech"},{"key":"287_CR22","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1016\/S0002-9440(10)63749-2","volume":"164","author":"MC Montesinos","year":"2004","unstructured":"Montesinos MC, Shaw JP, Yee H, Shamamian P, Cronstein BN (2004) Adenosine a(2a) receptor activation promotes wound neovascularization by stimulating angiogenesis and vasculogenesis. Am J Pathol 164:1887\u20131892","journal-title":"Am J Pathol"},{"key":"287_CR23","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1667\/0033-7587(2001)156[0232:IOASLP]2.0.CO;2","volume":"156","author":"CW Oh","year":"2001","unstructured":"Oh CW, Bump EA, Kim JS, Janigro D, Mayberg MR (2001) Induction of a senescence-like phenotype in bovine aortic endothelial cells by ionizing radiation. Radiat Res 156:232\u2013240","journal-title":"Radiat Res"},{"key":"287_CR24","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1046\/j.1440-1681.2001.03528.x","volume":"28","author":"YK On","year":"2001","unstructured":"On YK, Kim HS, Kim SY, Chae IH, Oh BH, Lee MM, Park YB, Choi YS, Chung MH (2001) Vitamin c prevents radiation-induced endothelium-dependent vasomotor dysfunction and de-endothelialization by inhibiting oxidative damage in the rat. Clin Exp Pharmacol Physiol 28:816\u2013821","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"287_CR25","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1667\/RR3049","volume":"160","author":"DL Preston","year":"2003","unstructured":"Preston DL, Shimizu Y, Pierce DA, Suyama A, Mabuchi K (2003) Studies of mortality of atomic bomb survivors. Report 13: solid cancer and noncancer disease mortality: 1950-1997. Radiat Res 160:381\u2013407","journal-title":"Radiat Res"},{"key":"287_CR26","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1038\/sj.bjp.0701654","volume":"123","author":"F Qi","year":"1998","unstructured":"Qi F, Sugihara T, Hattori Y, Yamamoto Y, Kanno M, Abe K (1998) Functional and morphological damage of endothelium in rabbit ear artery following irradiation with cobalt60. Br J Pharmacol 123:653\u2013660","journal-title":"Br J Pharmacol"},{"key":"287_CR27","doi-asserted-by":"crossref","first-page":"14","DOI":"10.2307\/3580045","volume":"152","author":"RW Rose","year":"1999","unstructured":"Rose RW, Grant DS, O\u2019Hara MD, Williamson SK (1999) The role of laminin-1 in the modulation of radiation damage in endothelial cells and differentiation. Radiat Res 152:14\u201328","journal-title":"Radiat Res"},{"key":"287_CR28","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/j.jacc.2007.09.059","volume":"51","author":"DP Sieveking","year":"2008","unstructured":"Sieveking DP, Buckle A, Celermajer DS, Ng MK (2008) Strikingly different angiogenic properties of endothelial progenitor cell subpopulations: insights from a novel human angiogenesis assay. J Am Coll Cardiol 51:660\u2013668","journal-title":"J Am Coll Cardiol"},{"key":"287_CR29","first-page":"1012","volume":"63","author":"P Sonveaux","year":"2003","unstructured":"Sonveaux P, Brouet A, Havaux X, Gregoire V, Dessy C, Balligand JL, Feron O (2003) Irradiation-induced angiogenesis through the up-regulation of the nitric oxide pathway: implications for tumor radiotherapy. Cancer Res 63:1012\u20131019","journal-title":"Cancer Res"},{"key":"287_CR30","doi-asserted-by":"crossref","unstructured":"Soucy KG, Lim HK, Benjo A, Santhanam L, Ryoo S, Shoukas AA, Vazquez ME, Berkowitz DE (2007) Single exposure gamma-irradiation amplifies xanthine oxidase activity and induces endothelial dysfunction in rat aorta. Radiat Environ Biophys 46:179\u2013186","DOI":"10.1007\/s00411-006-0090-z"},{"key":"287_CR31","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1096\/fj.07-8076com","volume":"22","author":"JL Spees","year":"2008","unstructured":"Spees JL, Whitney MJ, Sullivan DE, Lasky JA, Laboy M, Ylostalo J, Prockop DJ (2008) Bone marrow progenitor cells contribute to repair and remodeling of the lung and heart in a rat model of progressive pulmonary hypertension. Faseb J 22:1226\u20131236","journal-title":"Faseb J"},{"key":"287_CR32","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/S0033-8389(22)01790-0","volume":"9","author":"JR Stewart","year":"1971","unstructured":"Stewart JR, Fajardo LF (1971) Radiation-induced heart disease. Clinical and experimental aspects. Radiol Clin North Am 9:511\u2013531","journal-title":"Radiol Clin North Am"},{"key":"287_CR33","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1161\/01.CIR.100.6.635","volume":"100","author":"T Sugihara","year":"1999","unstructured":"Sugihara T, Hattori Y, Yamamoto Y, Qi F, Ichikawa R, Sato A, Liu MY, Abe K, Kanno M (1999) Preferential impairment of nitric oxide-mediated endothelium-dependent relaxation in human cervical arteries after irradiation. Circulation 100:635\u2013641","journal-title":"Circulation"},{"key":"287_CR34","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1161\/01.RES.0000137877.89448.78","volume":"95","author":"C Urbich","year":"2004","unstructured":"Urbich C, Dimmeler S (2004) Endothelial progenitor cells: characterization and role in vascular biology. Circ Res 95:343\u2013353","journal-title":"Circ Res"}],"container-title":["Radiation and Environmental Biophysics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00411-010-0287-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00411-010-0287-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00411-010-0287-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T20:56:06Z","timestamp":1685566566000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00411-010-0287-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4,18]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["287"],"URL":"https:\/\/doi.org\/10.1007\/s00411-010-0287-z","relation":{},"ISSN":["0301-634X","1432-2099"],"issn-type":[{"value":"0301-634X","type":"print"},{"value":"1432-2099","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4,18]]}}}