{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T04:44:00Z","timestamp":1649047440380},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2014,5,9]],"date-time":"2014-05-09T00:00:00Z","timestamp":1399593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Radiat Environ Biophys"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1007\/s00411-014-0542-9","type":"journal-article","created":{"date-parts":[[2014,5,8]],"date-time":"2014-05-08T12:58:18Z","timestamp":1399553898000},"page":"611-619","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Protective effect of an antithyroid compound against \u03b3-radiation-induced damage in human colon cancer cells"],"prefix":"10.1007","volume":"53","author":[{"given":"Marina","family":"Perona","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria A.","family":"Dagrosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romina","family":"Pagotto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana","family":"Casal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Pignataro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario A.","family":"Pisarev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo J.","family":"Juvenal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,5,9]]},"reference":[{"key":"542_CR1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0076-6879(84)05016-3","volume":"105","author":"H Aebi","year":"1984","unstructured":"Aebi H (1984) Catalase in vitro. Methods Enzymol 105:121\u2013126","journal-title":"Methods Enzymol"},{"key":"542_CR2","first-page":"60","volume-title":"Cancer facts and figures","author":"American Cancer Society","year":"2005","unstructured":"American Cancer Society (2005) Cancer facts and figures. American Cancer Society, Atlanta, p 60"},{"key":"542_CR3","first-page":"87","volume-title":"Basic clinical radiobiology","author":"SM Betzen","year":"1997","unstructured":"Betzen SM, Overgaard J (1997) Clinical manifestations of normal tissue damage. In: Steel GG (ed) Basic clinical radiobiology, 2nd edn. Oxford University Press, New York, pp 87\u201397","edition":"2"},{"key":"542_CR4","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1002\/jps.2600830220","volume":"83","author":"RT Blickenstaff","year":"1994","unstructured":"Blickenstaff RT, Brandstadter SM, Reddy S, Witt R (1994) Potential radioprotective agents. 1. Homologs of melatonin. J Pharm Sci 83:216\u2013218","journal-title":"J Pharm Sci"},{"key":"542_CR5","doi-asserted-by":"crossref","first-page":"2946","DOI":"10.1210\/jc.2006-0226","volume":"91","author":"SJ Bonnema","year":"2006","unstructured":"Bonnema SJ, Bennedbaek FN, Veje A, Marving J, Hegedus L (2006) Continuous methimazole therapy and its effect on the cure rate of hyperthyroidism using radioactive iodine: an evaluation by a randomized trial. J Clin Endocrinol Metab 91:2946\u20132951","journal-title":"J Clin Endocrinol Metab"},{"key":"542_CR6","first-page":"595","volume":"55","author":"AL Boynton","year":"1973","unstructured":"Boynton AL, Evans TC (1973) Investigation of effects of cyclic AMP and related drugs on recovery of radiation-induced mitotic delay in mouse ascites tumor cells. Radiat Res 55:595\u2013596","journal-title":"Radiat Res"},{"key":"542_CR7","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1126\/science.2981433","volume":"227","author":"PA Cerutti","year":"1985","unstructured":"Cerutti PA (1985) Prooxidant states and tumor promotion. Science 227:375\u2013380","journal-title":"Science"},{"key":"542_CR8","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0009-8981(03)00132-3","volume":"332","author":"J Chandra","year":"2003","unstructured":"Chandra J, Rajanikant GK, Rao SK, Shrinath Baliga M (2003) Alteration in the glutathione, glutathione peroxidase, superoxide dismutase and lipid peroxidation by ascorbic acid in the skin of mice exposed to fractionated \u03b3 radiation. Clin Chim Acta 332:111\u2013121","journal-title":"Clin Chim Acta"},{"key":"542_CR9","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1210\/er.2009-0007","volume":"31","author":"SY Cheng","year":"2010","unstructured":"Cheng SY, Leonard JL, Davis PJ (2010) Molecular aspects of thyroid hormone actions. Endocr Rev 31:139\u2013170","journal-title":"Endocr Rev"},{"key":"542_CR10","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1136\/bmj.1.5167.151","volume":"1","author":"J Crooks","year":"1960","unstructured":"Crooks J, Buchanan WW, Wayne EJ, Macdonald E (1960) Effect of pretreatment with methylthiouracil on results of I-131 therapy. Br Med J 1:151\u2013154","journal-title":"Br Med J"},{"key":"542_CR11","doi-asserted-by":"crossref","first-page":"7270","DOI":"10.1158\/0008-5472.CAN-05-4365","volume":"66","author":"FB Davis","year":"2006","unstructured":"Davis FB, Tang HY, Shih A, Keating T, Lansing L, Hercbergs AH, Fenstermaker RA, Mousa A, Mousa SA, Davis PJ, Lin HY (2006) Acting via a cell surface receptor, thyroid hormone is a growth factor for glioma cells. Cancer Res 66:7270\u20137275","journal-title":"Cancer Res"},{"key":"542_CR12","doi-asserted-by":"crossref","first-page":"5337","DOI":"10.1210\/endo.137.12.8940355","volume":"137","author":"K Punta Del","year":"1996","unstructured":"Del Punta K, Charreau EH, Pignataro OP (1996) Nitric oxide inhibits Leydig cell steroidogenesis. Endocrinology 137:5337\u20135343","journal-title":"Endocrinology"},{"key":"542_CR13","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1080\/09553000902985128","volume":"85","author":"SP Ghosh","year":"2009","unstructured":"Ghosh SP, Kulkarni S, Hieber K, Toles R, Romanyukha L, Kao TC, Hauer-Jensen M, Kumar KS (2009) Gamma-tocotrienol, a tocol antioxidant as a potent radioprotector. Int J Radiat Biol 85:598\u2013606","journal-title":"Int J Radiat Biol"},{"key":"542_CR14","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1159\/000067146","volume":"63","author":"DJ Grdina","year":"2002","unstructured":"Grdina DJ, Murley JS, Kataoka Y (2002) Radioprotectants: current status and new directions. Oncology 63:2\u201310","journal-title":"Oncology"},{"key":"542_CR15","first-page":"323","volume":"23","author":"JS Greenberger","year":"2009","unstructured":"Greenberger JS (2009) Radioprotection. In Vivo 23:323\u2013336","journal-title":"In Vivo"},{"key":"542_CR16","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1259\/0007-1285-38-445-72","volume":"38","author":"WR Greig","year":"1965","unstructured":"Greig WR, Crooks J, MacGregor AG, McIntosh JA (1965) The radioprotective effect of methylthiouracil on the thyroid gland of the rat. Br J Radiol 38:72\u201374","journal-title":"Br J Radiol"},{"key":"542_CR17","doi-asserted-by":"crossref","first-page":"352","DOI":"10.4161\/cc.10.2.14641","volume":"10","author":"AH Hercbergs","year":"2011","unstructured":"Hercbergs AH, Lin HY, Davis FB, Davis PJ, Leith JT (2011) Radiosensitization and production of DNA double-strand breaks in U87MG brain tumor cells induced by tetraiodothyroacetic acid (tetrac). Cell Cycle 10:352\u2013357","journal-title":"Cell Cycle"},{"key":"542_CR18","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1210\/en.2010-1163","volume":"152","author":"JM Hershman","year":"2011","unstructured":"Hershman JM, Okunyan A, Rivina Y, Cannon S, Hogen V (2011) Prevention of DNA double-strand breaks induced by radioiodide-(131)I in FRTL-5 thyroid cells. Endocrinology 152:1130\u20131135. doi: 10.1210\/en.2010-1163","journal-title":"Endocrinology"},{"key":"542_CR19","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1210\/jc.74.4.737","volume":"74","author":"AE Heufelder","year":"1992","unstructured":"Heufelder AE, Wenzel BE, Bahn RS (1992) Methimazole and propylthiouracil inhibit the oxygen free-radical induced expression of a 72 kilodalton heat shock protein in Graves\u2019 retroocular fibroblasts. J Clin Endocrinol Metab 74:737\u2013742","journal-title":"J Clin Endocrinol Metab"},{"key":"542_CR20","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/0006-2952(92)90561-V","volume":"43","author":"M Hicks","year":"1992","unstructured":"Hicks M, Woug LS, Day RO (1992) Antioxidant activity of propylthiouracil. Biochem Pharmacol 43:439\u2013444","journal-title":"Biochem Pharmacol"},{"key":"542_CR21","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1530\/acta.0.1120210","volume":"112","author":"M Imamura","year":"1986","unstructured":"Imamura M, Aoki N, Saito T, Ohno Y, Maruyama Y, Yamaguchi J, Yamamoto T (1986) Inhibitory effects of antithyroid drugs on oxygen radical formation in human neutrophils. Acta Endocrinol 112:210\u2013216","journal-title":"Acta Endocrinol"},{"key":"542_CR22","doi-asserted-by":"crossref","first-page":"811","DOI":"10.3109\/09553002.2010.488276","volume":"86","author":"C Kahmann","year":"2010","unstructured":"Kahmann C, Wunderlich G, Freudenberg R, Z\u00f6phel K, Oehme L, Kotzerke J (2010) Radioprotection of thyroid cells mediated by methimazole. Int J Radiat Biol 86:811\u2013816","journal-title":"Int J Radiat Biol"},{"key":"542_CR23","doi-asserted-by":"crossref","first-page":"107","DOI":"10.2307\/3574188","volume":"62","author":"S Lehnert","year":"1975","unstructured":"Lehnert S (1975) Modification of postirradiation survival of mammalian cells by intracellular cyclic AMP. Radiat Res 62:107\u2013116","journal-title":"Radiat Res"},{"key":"542_CR24","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"OH Lowry","year":"1951","unstructured":"Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265\u2013275","journal-title":"J Biol Chem"},{"key":"542_CR100","doi-asserted-by":"crossref","unstructured":"Mat\u00e9s JM, P\u00e9rez-G\u00f3mez C, N\u00fa\u00f1ez de Castro I (1999) Antioxidant enzymes and human diseases. Clin Biochem 32:595\u2013603","DOI":"10.1016\/S0009-9120(99)00075-2"},{"key":"542_CR25","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/166515a0","volume":"166","author":"RH Mole","year":"1950","unstructured":"Mole RH, Philpot JL, Hodges GR (1950) Reduction in lethal effect of x-radiation by pretreatment with thiourea or sodium ethane dithiophosphonate. Nature 166:515","journal-title":"Nature"},{"key":"542_CR26","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1667\/RR0758.1","volume":"167","author":"JS Murley","year":"2007","unstructured":"Murley JS, Kataoka Y, Baker KL, Diamond AM, Morgan WF, Grdina DJ (2007) Manganese superoxide dismutase (SOD2)-mediated delayed radioprotection induced by the free thiol form of amifostine and tumor necrosis factor alpha. Radiat Res 167:465\u2013474","journal-title":"Radiat Res"},{"key":"542_CR27","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1269\/jrr.42.21","volume":"42","author":"CKK Nair","year":"2001","unstructured":"Nair CKK, Parida DK, Nomura T (2001) Radioprotectors in radiotherapy. Journal of Radiat Res 42:21\u201337","journal-title":"Journal of Radiat Res"},{"key":"542_CR28","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1007\/BF01953816","volume":"36","author":"F Ojeda","year":"1980","unstructured":"Ojeda F, Aravena G, Folch H (1980) Modification of radiation response by agents that elevate the intracellular cAMP level. Experientia 36:857\u2013858","journal-title":"Experientia"},{"key":"542_CR29","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1667\/RR2658.1","volume":"179","author":"M Perona","year":"2013","unstructured":"Perona M, Dagrosa MA, Pagotto R, Casal M, Pignataro OP, Pisarev MA, Juvenal GJ (2013) Protection against radiation-induced damage of 6-propyl-2-thiouracil (PTU) in thyroid cells. Radiat Res 179:352\u2013360","journal-title":"Radiat Res"},{"key":"542_CR30","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1080\/rab.22.2.187.189","volume":"22","author":"KN Prasad","year":"1972","unstructured":"Prasad KN (1972) Radioprotective effect of prostaglandin and an inhibitor of cyclic nucleotide phosphodiesterase on mammalian cells in culture. Int J Radiat Biol Relat Stud Phys Chem Med 22:187\u2013189","journal-title":"Int J Radiat Biol Relat Stud Phys Chem Med"},{"key":"542_CR31","unstructured":"Prasad KN (1995) Modifications of cellular radiation damage. In: Handbook of radiobiology, 2nd edn. CRC Press, Cleveland"},{"key":"542_CR32","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.ijrobp.2011.06.2004","volume":"83","author":"S Rieken","year":"2012","unstructured":"Rieken S, Habermehl D, Wuerth L, Brons S, Mohr A, Lindel K, Weber K, Haberer T, Debus J, Combs SE (2012) Carbon ion irradiation inhibits glioma cell migration through downregulation of integrin expression. Int J Radiat Oncol Biol Phys 83:394\u2013399","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"542_CR33","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.1749-6632.1971.tb45229.x","volume":"185","author":"GA Robison","year":"1971","unstructured":"Robison GA, Sutherland EW (1971) Cyclic AMP and the function of eukaryotic cells: an introduction. Ann N Y Acad Sci 185:5\u2013189","journal-title":"Ann N Y Acad Sci"},{"key":"542_CR34","doi-asserted-by":"crossref","first-page":"516","DOI":"10.2307\/3577801","volume":"120","author":"E Ron","year":"1989","unstructured":"Ron E, Modan B, Preston D, Alfandary E, Stovall M, Boice JD Jr (1989) Thyroid neoplasia following low-dose radiation in childhood. Radiat Res 120:516\u2013531","journal-title":"Radiat Res"},{"key":"542_CR35","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1054\/drup.2001.0213","volume":"4","author":"IB Roninson","year":"2001","unstructured":"Roninson IB, Broude EV, Chang BD (2001) If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells. Drug Resist Update 4:303\u2013313","journal-title":"Drug Resist Update"},{"key":"542_CR36","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1089\/thy.1999.9.1181","volume":"9","author":"O Sabri","year":"1999","unstructured":"Sabri O, Zimny M, Schreckenberger M, Reinartz P, Ostwald E, Buell U (1999) Radioiodine therapy in Graves\u2019 disease patients with large diffuse goiters treated with or without carbimazole at the time of radioiodine therapy. Thyroid 9:1181\u20131188","journal-title":"Thyroid"},{"key":"542_CR38","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.ijrobp.2005.06.023","volume":"64","author":"AD Sasse","year":"2006","unstructured":"Sasse AD, Clark LG, Sasse EC, Clark OA (2006) Amifostine reduces side effects and improves complete response rate during radiotherapy: results of a meta-analysis. Int J Radiat Oncol Biol Phys 64:784\u2013791","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"542_CR39","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1080\/09553007114550251","volume":"19","author":"JF Scaife","year":"1971","unstructured":"Scaife JF (1971) Cyclic 3\u2032-5\u2032-adenosine monophosphate: its possible role in mammalian cell mitosis and radiation-induced mitotic G2-delay. Int J Radiat Biol Relat Stud Phys Chem Med 19:191\u2013195","journal-title":"Int J Radiat Biol Relat Stud Phys Chem Med"},{"key":"542_CR41","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1677\/joe.1.06574","volume":"189","author":"G Sener","year":"2006","unstructured":"Sener G, Kabasakal L, Atasoy BM, Erzik C, Velio\u011flu-O\u011f\u00fcn\u00e7 A, Cetinel S, Contuk G, Gedik N, Ye\u011fen BC (2006) Propylthiouracil-induced hypothyroidism protects ionizing radiation-induced multiple organ damage in rats. J Endocrinol 189:257\u2013269","journal-title":"J Endocrinol"},{"key":"542_CR42","unstructured":"Sonntag CV (1987) Protection, sensitization and the oxygen effect. In: The chemical basis of radiation Biology. Taylor and Francis, London"},{"key":"542_CR43","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1016\/j.freeradbiomed.2007.02.030","volume":"42","author":"BP Soule","year":"2007","unstructured":"Soule BP, Hyodo F, Matsumoto K, Simone NL, Cook JA, Krishna MC, Mitchell JB (2007) The chemistry and biology of nitroxide compounds. Free Radic Biol Med 42:1632\u20131650","journal-title":"Free Radic Biol Med"},{"key":"542_CR44","doi-asserted-by":"crossref","unstructured":"Stone HB, Moulder JE, Coleman CN, Ang KK, Anscher MS, Barcellos-Hoff MH, Dynan WS, Fike JR, Grdina DJ, Greenberger JS, Hauer-Jensen M, Hill RP, Kolesnick RN, Macvittie TJ, Marks C, McBride WH, Metting N, Pellmar T, Purucker M, Robbins ME, Schiestl RH, Seed TM, Tomaszewski JE, Travis EL, Wallner PE, Wolpert M, Zaharevitz D (2004) Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3\u20134, 2003. Radiat Res 162:711\u2013728","DOI":"10.1667\/RR3276"},{"key":"542_CR45","doi-asserted-by":"crossref","first-page":"621","DOI":"10.2307\/3573143","volume":"44","author":"JM Yuhas","year":"1970","unstructured":"Yuhas JM (1970) Biological factors affecting the radioprotective efficiency of S-2-[2-aminopropylamino] ethylphosphorothioic acid (WR-2721). LD50(3) doses. Radiat Res 44:621\u2013628","journal-title":"Radiat Res"}],"container-title":["Radiation and Environmental Biophysics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00411-014-0542-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00411-014-0542-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00411-014-0542-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T08:07:59Z","timestamp":1648973279000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00411-014-0542-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,9]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["542"],"URL":"https:\/\/doi.org\/10.1007\/s00411-014-0542-9","relation":{},"ISSN":["0301-634X","1432-2099"],"issn-type":[{"value":"0301-634X","type":"print"},{"value":"1432-2099","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,9]]}}}