{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T16:21:04Z","timestamp":1792858864224,"version":"4.5.0"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T00:00:00Z","timestamp":1649030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T00:00:00Z","timestamp":1649030400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["02NUK050A"],"award-info":[{"award-number":["02NUK050A"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["02NUK050A"],"award-info":[{"award-number":["02NUK050A"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["02NUK050A"],"award-info":[{"award-number":["02NUK050A"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["02NUK050A"],"award-info":[{"award-number":["02NUK050A"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010958","name":"GSI Helmholtzzentrum f\u00fcr Schwerionenforschung GmbH","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100010958","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Radiat Environ Biophys"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Radon-222 is pervasive in our environment and the second leading cause of lung cancer induction after smoking while it is simultaneously used to mediate anti-inflammatory effects. During exposure, radon gas distributes inhomogeneously in the body, making a spatially resolved dose quantification necessary to link physical exposure conditions with accompanying risks and beneficial effects. Current dose predictions rely on biokinetic models based on scarce input data from animal experiments and indirect exhalation measurements of a limited number of humans, which shows the need for further experimental verification. We present direct measurements of radon decay in the abdomen and thorax after inhalation as proof of principle in one patient. At both sites, most of the incorporated radon is removed within\u2009~\u20093\u00a0h, whereas a smaller fraction is retained longer and accounts for most of the deposited energy. The obtained absorbed dose values were <jats:inline-formula><jats:alternatives><jats:tex-math>$$1.5 \\pm 0.3$$<\/jats:tex-math><mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\">\n                  <mml:mrow>\n                    <mml:mn>1.5<\/mml:mn>\n                    <mml:mo>\u00b1<\/mml:mo>\n                    <mml:mn>0.3<\/mml:mn>\n                  <\/mml:mrow>\n                <\/mml:math><\/jats:alternatives><\/jats:inline-formula>\u00a0\u00b5Gy (abdomen, radon gas) and <jats:inline-formula><jats:alternatives><jats:tex-math>$$1.1 \\pm 0.4$$<\/jats:tex-math><mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\">\n                  <mml:mrow>\n                    <mml:mn>1.1<\/mml:mn>\n                    <mml:mo>\u00b1<\/mml:mo>\n                    <mml:mn>0.4<\/mml:mn>\n                  <\/mml:mrow>\n                <\/mml:math><\/jats:alternatives><\/jats:inline-formula>\u00a0\u00b5Gy (thorax, radon and progeny) for a one-hour reference exposure at a radon activity concentration of 55 kBq\u00a0m<jats:sup>\u22123<\/jats:sup>. The accumulation of long-retained radon in the abdomen leads to higher dose values at that site than in the thorax. Contrasting prior work, our measurements are performed directly at specific body sites, i.e. thorax and abdomen, which allows for direct spatial distinction of radon kinetics in the body. They show more incorporated and retained radon than current approaches predict, suggesting higher doses. Although obtained only from one person, our data may thus represent a challenge for the barely experimentally benchmarked biokinetic dose assessment model.<\/jats:p>","DOI":"10.1007\/s00411-022-00972-8","type":"journal-article","created":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T08:05:33Z","timestamp":1649059533000},"page":"279-292","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["In-vivo dose determination in a human after radon exposure: proof of principle"],"prefix":"10.1007","volume":"61","author":[{"given":"Franziska","family":"Papenfu\u00df","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Maier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Fournier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Kraft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Friedrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,4,4]]},"reference":[{"key":"972_CR1","unstructured":"Andersson I, Nilsson I (1964) Exposure following ingestion of water containing radon-222. In: Assessment of radioactivity in man. Vol. II. Proceedings of the symposium on the assessment of radioactive body burdens"},{"issue":"3","key":"972_CR2","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1504\/IJLR.2004.005434","volume":"1","author":"K Becker","year":"2004","unstructured":"Becker K (2004) One century of radon therapy. Int J Low Radiat 1(3):333\u2013357","journal-title":"Int J Low Radiat"},{"key":"972_CR3","volume-title":"Health risk of radon and other internally deposited alpha emitters: Beir IV","author":"BEIR","year":"1988","unstructured":"BEIR (1988) Health risk of radon and other internally deposited alpha emitters: Beir IV. National Academies Press, Washington, DC"},{"key":"972_CR4","doi-asserted-by":"publisher","unstructured":"Berger MJ, Coursey JS, Zucker MA, Chang J (2020) Stopping power and range tables for electrons, protons, and helium ions. NIST Standard Reference Database 124. https:\/\/doi.org\/10.18434\/T4NC7P","DOI":"10.18434\/T4NC7P"},{"issue":"1\u20132","key":"972_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ijpharm.2010.12.040","volume":"406","author":"TC Carvalho","year":"2011","unstructured":"Carvalho TC, Peters JI, Williams RO III (2011) Influence of particle size on regional lung deposition\u2014what evidence is there? Int J Pharm 406(1\u20132):1\u201310","journal-title":"Int J Pharm"},{"key":"972_CR6","unstructured":"Chu SYF, Ekstr\u00f6m LP, Firestone RB (1999) The Lund\/LBNL Nuclear Data Search. http:\/\/nucleardatanuclearluse\/toi\/"},{"issue":"6","key":"972_CR7","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1021\/es00171a016","volume":"22","author":"KD Chu","year":"1988","unstructured":"Chu KD, Hopke PK (1988) Neutralization kinetics for polonium-218. Environ Sci Technol 22(6):711\u2013717","journal-title":"Environ Sci Technol"},{"issue":"7485","key":"972_CR8","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1136\/bmj.38308.477650.63","volume":"330","author":"S Darby","year":"2005","unstructured":"Darby S, Hill D, Auvinen A, Barros-Dios J, Baysson H, Bochicchio F, Deo H, Falk R, Forastiere F, Hakama M (2005) Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studies. BMJ 330(7485):223. https:\/\/doi.org\/10.1136\/bmj.38308.477650.63","journal-title":"BMJ"},{"issue":"05","key":"972_CR9","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1055\/s-0034-1384554","volume":"39","author":"G Dischereit","year":"2014","unstructured":"Dischereit G, Neumann N, M\u00fcller-Ladner U, K\u00fcrten B, Lange U (2014) Einfluss einer seriellen niedrig-dosierten Radonstollen-Hyperthermie auf Schmerz, Krankheitsaktivit\u00e4t und zentrale Zytokine des Knochenmetabolismus bei ankylosierender Spondylitis\u2013eine Prospektivstudie. Aktuelle Rheumatologie 39(05):304\u2013309","journal-title":"Aktuelle Rheumatologie"},{"issue":"2","key":"972_CR10","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1093\/rpd\/ncaa144","volume":"191","author":"P Fojtik","year":"2020","unstructured":"Fojtik P, H\u016flka J, Bartl P, J\u00edlek K, Mal\u00e1tov\u00e1 I, Kot\u00edk L, Rul\u00edk P, Rubovi\u010d P, \u0160tekl I (2020) Radon inhalation experiments to test radon exhalation kinetics. Radiat Prot Dosim 191(2):176\u2013180","journal-title":"Radiat Prot Dosim"},{"issue":"11","key":"972_CR11","doi-asserted-by":"publisher","first-page":"2839","DOI":"10.1007\/s00296-013-2819-8","volume":"33","author":"A Franke","year":"2013","unstructured":"Franke A, Franke T (2013) Long-term benefits of radon spa therapy in rheumatic diseases: results of the randomised, multi-centre IMuRa trial. Rheumatol Int 33(11):2839\u20132850","journal-title":"Rheumatol Int"},{"issue":"6","key":"972_CR12","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1097\/00004032-199012000-00016","volume":"59","author":"T Gosink","year":"1990","unstructured":"Gosink T, Baskaran M, Holleman D (1990) Radon in the human body from drinking water. Health Phys 59(6):919\u2013924","journal-title":"Health Phys"},{"issue":"5","key":"972_CR13","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/0160-4120(94)90004-3","volume":"20","author":"JH Harley","year":"1994","unstructured":"Harley JH, Jetter ES, Nelson N (1994) Elimination of radon from the body. Environ Int 20(5):573\u2013584","journal-title":"Environ Int"},{"issue":"2","key":"972_CR14","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1007\/BF02041517","volume":"203","author":"P Hopke","year":"1996","unstructured":"Hopke P (1996) The initial atmospheric behavior of radon decay products. J Radioanal Nucl Chem 203(2):353\u2013375","journal-title":"J Radioanal Nucl Chem"},{"issue":"6","key":"972_CR15","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1097\/00004032-196506000-00001","volume":"11","author":"JB Hursh","year":"1965","unstructured":"Hursh JB, Morken DA, Davis TP, Lovaas A (1965) The fate of radon ingested by man. Health Phys 11(6):465\u2013476","journal-title":"Health Phys"},{"key":"972_CR16","unstructured":"ICRP (1975) Report of the Task Group on Reference Man, ICRP Publication 23. Ann ICRP"},{"key":"972_CR17","doi-asserted-by":"crossref","unstructured":"ICRP (1994) Human Respiratory Tract Model for Radiological Protection, ICRP Publication 66. Ann ICRP 24","DOI":"10.1016\/0146-6453(94)90018-3"},{"key":"972_CR18","doi-asserted-by":"crossref","unstructured":"ICRP (2003) Relative biological effectiveness (RBE), quality factor (Q), and radiation weighting factor (wR), ICRP Publication 92. Ann ICRP 33 (4)","DOI":"10.1016\/S0146-6453(03)00024-1"},{"key":"972_CR19","unstructured":"ICRP (2007) Recommendations of the International Commission on Radiological Protection, ICRP Publication 103. Ann ICRP 37 (2\u20134)"},{"key":"972_CR20","unstructured":"ICRP (2015) Occupational intakes of radionuclides: Part 1, ICRP Publication 130. Ann ICRP 46"},{"key":"972_CR21","doi-asserted-by":"publisher","unstructured":"ICRP (2017) Occupational intakes of radionuclides: Part 3, ICRP Publication 137. Ann ICRP 46 ((3\/4)). doi:https:\/\/doi.org\/10.1177\/0146645317734963","DOI":"10.1177\/0146645317734963"},{"issue":"2","key":"972_CR22","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.mrrev.2012.12.001","volume":"752","author":"M Kadhim","year":"2013","unstructured":"Kadhim M, Salomaa S, Wright E, Hildebrandt G, Belyakov OV, Prise KM, Little MP (2013) Non-targeted effects of ionising radiation\u2014implications for low dose risk. Mutat Res 752(2):84\u201398","journal-title":"Mutat Res"},{"issue":"2","key":"972_CR23","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1093\/oxfordjournals.rpd.a033035","volume":"88","author":"A Khursheed","year":"2000","unstructured":"Khursheed A (2000) Doses to systemic tissues from radon gas. Radiat Prot Dosim 88(2):171\u2013181. https:\/\/doi.org\/10.1093\/oxfordjournals.rpd.a033035","journal-title":"Radiat Prot Dosim"},{"issue":"1","key":"972_CR24","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1007\/s00411-018-0768-z","volume":"58","author":"M Kullmann","year":"2019","unstructured":"Kullmann M, R\u00fchle PF, Harrer A, Donaubauer A, Becker I, Sieber R, Klein G, Fournier C, Fietkau R, Gaipl US (2019) Temporarily increased TGF\u03b2 following radon spa correlates with reduced pain while serum IL-18 is a general predictive marker for pain sensitivity. Radiat Environ Biophys 58(1):129\u2013135","journal-title":"Radiat Environ Biophys"},{"issue":"2","key":"972_CR25","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1088\/0952-4746\/33\/2\/413","volume":"33","author":"R Leggett","year":"2013","unstructured":"Leggett R, Marsh J, Gregoratto D, Blanchardon E (2013) A generic biokinetic model for noble gases with application to radon. J Radiol Prot 33(2):413","journal-title":"J Radiol Prot"},{"issue":"12","key":"972_CR26","doi-asserted-by":"publisher","first-page":"5996","DOI":"10.1073\/pnas.94.12.5996","volume":"94","author":"JB Little","year":"1997","unstructured":"Little JB (1997) What are the risks of low-level exposure to \u03b1 radiation from radon? Proc Natl Acad Sci 94(12):5996\u20135997","journal-title":"Proc Natl Acad Sci"},{"issue":"1","key":"972_CR27","doi-asserted-by":"publisher","first-page":"316","DOI":"10.3390\/ijms22010316","volume":"22","author":"A Maier","year":"2021","unstructured":"Maier A, Wiedemann J, Rapp F, Papenfu\u00df F, R\u00f6del F, Hehlgans S, Gaipl US, Kraft G, Fournier C, Frey B (2021) Radon exposure\u2014therapeutic effect and cancer risk. Int J Mol Sci 22(1):316","journal-title":"Int J Mol Sci"},{"issue":"40","key":"972_CR28","doi-asserted-by":"publisher","first-page":"14127","DOI":"10.1073\/pnas.0507119102","volume":"102","author":"WF Morgan","year":"2005","unstructured":"Morgan WF, Sowa MB (2005) Effects of ionizing radiation in nonirradiated cells. Proc Natl Acad Sci 102(40):14127\u201314128","journal-title":"Proc Natl Acad Sci"},{"issue":"3","key":"972_CR29","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/s00411-016-0657-2","volume":"55","author":"W-U M\u00fcller","year":"2016","unstructured":"M\u00fcller W-U, Giussani A, R\u00fchm W, Lecomte J-F, Harrison J, Kreuzer M, Sobotzki C, Breckow J (2016) Current knowledge on radon risk: implications for practical radiation protection? radon workshop, 1\/2 December 2015, Bonn, BMUB (Bundesministerium f\u00fcr Umwelt, Naturschutz, Bau und Reaktorsicherheit; Federal Ministry for the Environment, Nature Conservation, Building and Nuclear Safety). Radiat Environ Biophys 55(3):267\u2013280","journal-title":"Radiat Environ Biophys"},{"key":"972_CR30","volume-title":"Risk assessment of radon in drinking water","author":"NRC","year":"1999","unstructured":"NRC (1999) Risk assessment of radon in drinking water. National Academies Press, Washington, DC"},{"issue":"3247","key":"972_CR31","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1126\/science.125.3247.552","volume":"125","author":"E Nussbaum","year":"1957","unstructured":"Nussbaum E, Hursh J (1957) Radon solubility in rat tissues. Science 125(3247):552\u2013553. https:\/\/doi.org\/10.1126\/science.125.3247.552","journal-title":"Science"},{"issue":"6467","key":"972_CR32","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1038\/368097a0","volume":"368","author":"J Peto","year":"1994","unstructured":"Peto J, Darby S (1994) Radon risk reassessed. Nature 368(6467):97\u201398","journal-title":"Nature"},{"issue":"2","key":"972_CR33","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/0021-8502(94)90077-9","volume":"25","author":"J Porstend\u00f6rfer","year":"1994","unstructured":"Porstend\u00f6rfer J (1994) Properties and behaviour of radon and thoron and their decay products in the air. J Aerosol Sci 25(2):219\u2013263. https:\/\/doi.org\/10.1016\/0021-8502(94)90077-9","journal-title":"J Aerosol Sci"},{"issue":"2","key":"972_CR34","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1080\/08916934.2017.1284819","volume":"50","author":"PF R\u00fchle","year":"2017","unstructured":"R\u00fchle PF, Wunderlich R, Deloch L, Fournier C, Maier A, Klein G, Fietkau R, Gaipl US, Frey B (2017) Modulation of the peripheral immune system after low-dose radon spa therapy: detailed longitudinal immune monitoring of patients within the RAD-ON01 study. Autoimmunity 50(2):133\u2013140","journal-title":"Autoimmunity"},{"issue":"8","key":"972_CR35","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1080\/18811248.2010.9711649","volume":"47","author":"A Sakoda","year":"2010","unstructured":"Sakoda A, Ishimori Y, Kawabe A, Kataoka T, Hanamoto K, Yamaoka K (2010) Physiologically based pharmacokinetic modeling of inhaled radon to calculate absorbed doses in mice, rats, and humans. J Nucl Sci Technol 47(8):731\u2013738","journal-title":"J Nucl Sci Technol"},{"issue":"1","key":"972_CR36","doi-asserted-by":"publisher","first-page":"10768","DOI":"10.1038\/s41598-019-47236-y","volume":"9","author":"EP Sanjon","year":"2019","unstructured":"Sanjon EP, Maier A, Hinrichs A, Kraft G, Drossel B, Fournier C (2019) A combined experimental and theoretical study of radon solubility in fat and water. Sci Rep 9(1):10768. https:\/\/doi.org\/10.1038\/s41598-019-47236-y","journal-title":"Sci Rep"},{"issue":"1","key":"972_CR37","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1103\/RevModPhys.82.383","volume":"82","author":"D Schardt","year":"2010","unstructured":"Schardt D, Els\u00e4sser T, Schulz-Ertner D (2010) Heavy-ion tumor therapy: physical and radiobiological benefits. Rev Mod Phys 82(1):383","journal-title":"Rev Mod Phys"},{"issue":"9\u201310","key":"972_CR38","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1007\/s00508-006-0560-y","volume":"118","author":"M Shehata","year":"2006","unstructured":"Shehata M, Schwarzmeier JD, Hilgarth M, Demirtas D, Richter D, Hubmann R, Boeck P, Leiner G, Falkenbach A (2006) Effect of combined spa-exercise therapy on circulating TGF-\u03b21 levels in patients with ankylosing spondylitis. Wien Klin Wochenschr 118(9\u201310):266\u2013272","journal-title":"Wien Klin Wochenschr"},{"key":"972_CR39","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1155\/2012\/510876","volume":"2012","author":"M Smerajec","year":"2012","unstructured":"Smerajec M, Vaupoti\u010d J (2012) Nanoaerosols including radon decay products in outdoor and indoor air at a suburban site. J Toxicol 2012:31. https:\/\/doi.org\/10.1155\/2012\/510876","journal-title":"J Toxicol"},{"key":"972_CR40","doi-asserted-by":"crossref","unstructured":"S\u00f3ti Z, Magill J, Dreher R (2019) Karlsruhe Nuclide Chart\u2014New 10th edition 2018 EPJ Nuclear Sci Technol 5:6","DOI":"10.1051\/epjn\/2019004"},{"issue":"1","key":"972_CR41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-018-34213-0","volume":"8","author":"P St\u00f6rchle","year":"2018","unstructured":"St\u00f6rchle P, M\u00fcller W, Sengeis M, Lackner S, Holasek S, F\u00fcrhapter-Rieger A (2018) Measurement of mean subcutaneous fat thickness: eight standardised ultrasound sites compared to 216 randomly selected sites. Sci Rep 8(1):1\u201312","journal-title":"Sci Rep"},{"key":"972_CR42","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1289\/ehp.8455369","volume":"55","author":"BO Stuart","year":"1984","unstructured":"Stuart BO (1984) Deposition and clearance of inhaled particles. Environ Health Perspect 55:369\u2013390","journal-title":"Environ Health Perspect"},{"key":"972_CR43","volume-title":"Sources and effects of ionizing radiation UNSCEAR 2000 report to the General Assembly, with scientific annexes","author":"UNSCEAR","year":"2000","unstructured":"UNSCEAR (2000) Sources and effects of ionizing radiation UNSCEAR 2000 report to the General Assembly, with scientific annexes. United Nations, New York"},{"key":"972_CR44","volume-title":"Effects of ionizing radiation. United Nations Scientific Committee on the Effects of Atomic Radiation: UNSCEAR 2006 report to the General Assembly","author":"UNSCEAR","year":"2006","unstructured":"UNSCEAR (2006) Effects of ionizing radiation. United Nations Scientific Committee on the Effects of Atomic Radiation: UNSCEAR 2006 report to the General Assembly. Annex E United Nations, New York"},{"key":"972_CR45","volume-title":"Sources, effects and risks of ionizing radiation. United Natiens Scientific Committee on the Effects of Atomic Radiation: UNSCEAR 2017 report to the general assembly with scientific annexes","author":"UNSCEAR","year":"2017","unstructured":"UNSCEAR (2017) Sources, effects and risks of ionizing radiation. United Natiens Scientific Committee on the Effects of Atomic Radiation: UNSCEAR 2017 report to the general assembly with scientific annexes. United Nations, New York"}],"container-title":["Radiation and Environmental Biophysics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00411-022-00972-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00411-022-00972-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00411-022-00972-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T05:14:58Z","timestamp":1650431698000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00411-022-00972-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,4]]},"references-count":45,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["972"],"URL":"https:\/\/doi.org\/10.1007\/s00411-022-00972-8","relation":{},"ISSN":["0301-634X","1432-2099"],"issn-type":[{"value":"0301-634X","type":"print"},{"value":"1432-2099","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,4]]},"assertion":[{"value":"3 December 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 March 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 April 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no conflict of interest to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The experiments were performed in accordance with relevant guidelines and regulations. The measurements were conducted after regular, medically prescribed therapy and therefore no ethical vote was necessary, as confirmed by the ethics commission of Goethe University Frankfurt (22.10.2018).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"All subjects gave their informed consent for inclusion before they participated in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"All subjects gave their informed consent for publication before they participated in the study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}