{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:23:45Z","timestamp":1761708225690},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2008,8,7]],"date-time":"2008-08-07T00:00:00Z","timestamp":1218067200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Legal Med"],"published-print":{"date-parts":[[2009,9]]},"DOI":"10.1007\/s00414-008-0278-7","type":"journal-article","created":{"date-parts":[[2008,8,6]],"date-time":"2008-08-06T08:49:13Z","timestamp":1218012553000},"page":"371-379","source":"Crossref","is-referenced-by-count":11,"title":["Hyperthermia combined with ethanol administration induces c-fos expression in the central amygdaloid nucleus of the mouse brain. A possible mechanism of heatstroke under the influence of ethanol intake"],"prefix":"10.1007","volume":"123","author":[{"given":"Kazuhiko","family":"Kibayashi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken-ichiro","family":"Nakao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Shojo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,8,7]]},"reference":[{"key":"278_CR1","first-page":"577","volume":"44","author":"Centers for Disease Control and Prevention","year":"1995","unstructured":"Centers for Disease Control and Prevention (1995) Heat-related mortality\u2014Chicago, July 1995. MMWR Morb Mortal Wkly Rep 44:577\u2212579","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"278_CR2","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1056\/NEJMra011089","volume":"346","author":"A Bouchama","year":"2002","unstructured":"Bouchama A, Knochel JP (2002) Heat stroke. N Engl J Med 346:1978\u22121988","journal-title":"N Engl J Med"},{"key":"278_CR3","doi-asserted-by":"crossref","first-page":"173\u2212181","DOI":"10.7326\/0003-4819-129-3-199808010-00001","volume":"129","author":"JE Dematte","year":"1998","unstructured":"Dematte JE, O\u2019Mara K, Buescher J, Whitney CG, Forsythe S, McNamee T, Adiga RB, Ndukwu M (1998) Near-fatal heat stroke during the 1995 heat wave in Chicago. Ann Intern Med 129:173\u2212181","journal-title":"Ann Intern Med"},{"key":"278_CR4","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1097\/00000433-200106000-00018","volume":"22","author":"H Green","year":"2001","unstructured":"Green H, Gilbert J, James R, Byard RW (2001) An analysis of factors contributing to a series of deaths caused by exposure to high environmental temperatures. Am J Forensic Med Pathol 22:196\u2013199","journal-title":"Am J Forensic Med Pathol"},{"key":"278_CR5","first-page":"473","volume":"47","author":"Centers for Disease Control and Prevention","year":"1998","unstructured":"Centers for Disease Control and Prevention (1998) Heat-related mortality\u2014United States, 1997. MMWR Morb Mortal Wkly Rep 47:473\u2013476","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"278_CR6","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S1353-1131(98)90131-6","volume":"5","author":"PM Ng\u2019walali","year":"1998","unstructured":"Ng\u2019walali PM, Kibayashi K, Yonemitsu K, Ohtsu Y, Tsunenari S (1998) Death as a result of heat stroke in a vehicle: an adult case in winter confirmed with reconstruction and animal experiments. J Clin Forensic Med 5:183\u2013186","journal-title":"J Clin Forensic Med"},{"key":"278_CR7","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/S0002-9343(00)00671-9","volume":"110","author":"ML Hannuksela","year":"2001","unstructured":"Hannuksela ML, Ellahham S (2001) Benefits and risks of sauna bathing. Am J Med 110:118\u2013126","journal-title":"Am J Med"},{"key":"278_CR8","first-page":"25","volume-title":"The Gale encyclopedia of neurological disorders","author":"LF Gulli","year":"2005","unstructured":"Gulli LF, Mooney M (2005) Alcohol-related neurological disease. In: Chamberlin SL, Narins B (eds) The Gale encyclopedia of neurological disorders. Thomson Gale, Detroit, pp 25\u201329"},{"key":"278_CR9","first-page":"415","volume-title":"Pathologic basis of disease","author":"AB Kane","year":"2005","unstructured":"Kane AB, Kumar V (2005) Environmental and nutritional pathology. In: Kumar V, Abbas AK, Fausto N (eds) Pathologic basis of disease. 7th edn. Elsevier, Philadelphia, pp 415\u2013468","edition":"7"},{"key":"278_CR10","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1126\/science.3131879","volume":"240","author":"SM Sagar","year":"1988","unstructured":"Sagar SM, Sharp FR, Curran T (1988) Expression of c-fos protein in brain: metabolic mapping at the cellular level. Science 240:1328\u20131331","journal-title":"Science"},{"key":"278_CR11","doi-asserted-by":"crossref","first-page":"9569","DOI":"10.1073\/pnas.86.23.9569","volume":"86","author":"S Ceccatelli","year":"1989","unstructured":"Ceccatelli S, Villar MJ, Goldstein M, H\u00f6kfelt T (1989) Expression of c-Fos immunoreactivity in transmitter-characterized neurons after stress. Proc Natl Acad Sci U S A 86:9569\u20139573","journal-title":"Proc Natl Acad Sci U S A"},{"key":"278_CR12","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1097\/01.ALC.0000122765.58324.6D","volume":"28","author":"BE Herring","year":"2004","unstructured":"Herring BE, Mayfield RD, Camp MC, Alcantara AA (2004) Ethanol-induced fos immunoreactivity in the extended amygdala and hypothalamus of the rat brain: focus on cholinergic interneurons of the nucleus accumbens. Alcohol Clin Exp Res 28:588\u2013597","journal-title":"Alcohol Clin Exp Res"},{"key":"278_CR13","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1046\/j.1471-4159.1996.66031140.x","volume":"66","author":"SC Papasozomenos","year":"1996","unstructured":"Papasozomenos SC (1996) Heat shock induces rapid dephosphorylation of \u03c4 in both female and male rats followed by hyperphosphorylation only in female rats: implications for Alzheimer\u2019s disease. J Neurochem 66:1140\u20131149","journal-title":"J Neurochem"},{"key":"278_CR14","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1097\/01.shk.0000159557.95285.96","volume":"23","author":"C-H Hung","year":"2005","unstructured":"Hung C-H, Chang N-C, Cheng B-C, Lin M-T (2005) Progressive exercise preconditioning protects against circulatory shock during experimental heatstroke. Shock 23:426\u2013433","journal-title":"Shock"},{"key":"278_CR15","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.alcohol.2005.07.008","volume":"37","author":"K Keiver","year":"2005","unstructured":"Keiver K, Duggal S, Simpson ME (2005) Ethanol administration results in a prolonged decrease in blood ionized calcium levels in the rat. Alcohol 37:173\u2013178","journal-title":"Alcohol"},{"key":"278_CR16","volume-title":"The mouse brain in stereotaxic coordinates","author":"G Paxinos","year":"2001","unstructured":"Paxinos G, Franklin KBJ (2001) The mouse brain in stereotaxic coordinates, 2nd edn. Academic, San Diego (fig. 44)","edition":"2"},{"key":"278_CR17","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1159\/000188763","volume":"71","author":"S-D Shieh","year":"1995","unstructured":"Shieh S-D, Lin Y-F, Lin S-H, Lu K-C (1995) A prospective study of calcium metabolism in exertional heat stroke with rhabdomyolysis and acute renal failure. Nephron 71:428\u2013432","journal-title":"Nephron"},{"key":"278_CR18","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0304-3940(99)00030-0","volume":"262","author":"H-J Tsay","year":"1999","unstructured":"Tsay H-J, Li H-Y, Lin C-H, Yang Y-L, Yeh J-Y, Lin M-T (1999) Heatstroke induces c-fos expression in the rat hypothalamus. Neurosci Lett 262:41\u201344","journal-title":"Neurosci Lett"},{"key":"278_CR19","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.brainresbull.2003.07.001","volume":"61","author":"N Harikai","year":"2003","unstructured":"Harikai N, Tomogane K, Sugawara T, Tashiro S (2003) Differences in hypothalamic Fos expressions between two heat stress conditions in conscious mice. Brain Res Bull 61:617\u2013626","journal-title":"Brain Res Bull"},{"key":"278_CR20","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.yfrne.2003.07.001","volume":"24","author":"JP Herman","year":"2003","unstructured":"Herman JP, Figueiredo H, Mueller NK, Ulrich-Lai Y, Ostrander MM, Choi DC, Cullinan WE (2003) Central mechanisms of stress integration: hierarchical circuitry controlling hypothalamo-pituitary-adrenocortical responsiveness. Front Neuroendocrinol 24:151\u2013180","journal-title":"Front Neuroendocrinol"},{"key":"278_CR21","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1002\/(SICI)1096-9861(19970324)379:4<592::AID-CNE9>3.0.CO;2-Y","volume":"379","author":"NC Tkacs","year":"1997","unstructured":"Tkacs NC, Li J, Strack AM (1997) Central amygdala Fos expression during hypotensive or febrile, nonhypotensive endotoxemia in conscious rats. J Comp Neurol 379:592\u2013602","journal-title":"J Comp Neurol"},{"key":"278_CR22","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1159\/000087924","volume":"81","author":"J Weidenfeld","year":"2005","unstructured":"Weidenfeld J, Itzik A, Goshen I, Yirmiya R, Ben-Hur T (2005) Role of the central amygdala in modulating the pituitary\u2013adrenocortical and clinical responses in experimental herpes simplex virus-1 encephalitis. Neuroendocrinology 81:267\u2013272","journal-title":"Neuroendocrinology"},{"key":"278_CR23","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1146\/annurev.ne.15.030192.002033","volume":"15","author":"M Davis","year":"1992","unstructured":"Davis M (1992) The role of the amygdala in fear and anxiety. Annu Rev Neurosci 15:353\u2013375","journal-title":"Annu Rev Neurosci"},{"key":"278_CR24","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1113\/jphysiol.2004.066654","volume":"558","author":"MC Almeida","year":"2004","unstructured":"Almeida MC, Steiner AA, Coimbra NC, Branco LGS (2004) Thermoeffector neuronal pathways in fever: a study in rats showing a new role of the locus coeruleus. J Physiol 558:283\u2013294","journal-title":"J Physiol"},{"key":"278_CR25","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S0091-3057(01)00680-3","volume":"71","author":"WJ McBride","year":"2002","unstructured":"McBride WJ (2002) Central nucleus of the amygdala and the effects of alcohol and alcohol-drinking behavior in rodents. Pharmacol Biochem Behav 71:509\u2013515","journal-title":"Pharmacol Biochem Behav"},{"key":"278_CR26","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/0165-1838(95)00032-S","volume":"55","author":"JC Graham","year":"1995","unstructured":"Graham JC, Hoffman GE, Sved AF (1995) C-Fos expression in brain in response to hypotension and hypertension in conscious rats. J Auton Nerv Syst 55:92\u2013104","journal-title":"J Auton Nerv Syst"},{"key":"278_CR27","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1097\/01.CCM.0000224231.01533.B1","volume":"34","author":"C-M Chen","year":"2006","unstructured":"Chen C-M, Hou C-C, Cheng K-C, Tian R-L, Chang C-P, Lin M-T (2006) Activated protein C therapy in a rat heat stroke model. Crit Care Med 34:1960\u20131966","journal-title":"Crit Care Med"},{"key":"278_CR28","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.neuroscience.2004.05.016","volume":"127","author":"A Bratincs\u00e1k","year":"2004","unstructured":"Bratincs\u00e1k A, Palkovits M (2004) Activation of brain areas in rat following warm and cold ambient exposure. Neuroscience 127:385\u2013397","journal-title":"Neuroscience"},{"key":"278_CR29","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s00414-007-0181-7","volume":"122","author":"AW Jones","year":"2008","unstructured":"Jones AW (2008) Ultra-rapid rate of ethanol elimination from blood in drunken drivers with extremely high blood-alcohol concentrations. Int J Leg Med 122:129\u2013134","journal-title":"Int J Leg Med"},{"key":"278_CR30","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s00414-007-0185-3","volume":"122","author":"T Fracasso","year":"2008","unstructured":"Fracasso T, Brinkmann B, Beike J, Pfeiffer H (2008) Clotted blood as sign of alcohol intoxication: a retrospective study. Int J Leg Med 122:157\u2013161","journal-title":"Int J Leg Med"}],"container-title":["International Journal of Legal Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00414-008-0278-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00414-008-0278-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00414-008-0278-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T18:56:38Z","timestamp":1559069798000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00414-008-0278-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8,7]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["278"],"URL":"https:\/\/doi.org\/10.1007\/s00414-008-0278-7","relation":{},"ISSN":["0937-9827","1437-1596"],"issn-type":[{"value":"0937-9827","type":"print"},{"value":"1437-1596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,8,7]]}}}