{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:21:06Z","timestamp":1763036466998,"version":"build-2065373602"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2010,4,6]],"date-time":"2010-04-06T00:00:00Z","timestamp":1270512000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Legal Med"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1007\/s00414-010-0449-1","type":"journal-article","created":{"date-parts":[[2010,4,7]],"date-time":"2010-04-07T00:19:43Z","timestamp":1270599583000},"page":"647-651","source":"Crossref","is-referenced-by-count":20,"title":["Buprenorphine-related deaths: unusual forensic situations"],"prefix":"10.1007","volume":"124","author":[{"given":"Anne-Laure","family":"Pelissier-Alicot","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Sastre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valerie","family":"Baillif-Couniou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Michel","family":"Gaulier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Kintz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika","family":"Kuhlmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Perich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe","family":"Bartoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Dominique","family":"Piercecchi-Marti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georges","family":"Leonetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,4,6]]},"reference":[{"key":"449_CR1","first-page":"183","volume":"27","author":"G Rolly","year":"1976","unstructured":"Rolly G, Versichelen L (1976) Buprenorphine as postoperative analgesic. Acta Anaesthesiol Belg 27:183\u2013186","journal-title":"Acta Anaesthesiol Belg"},{"key":"449_CR2","first-page":"187","volume":"27","author":"H Adriaensen","year":"1976","unstructured":"Adriaensen H, Van De Walle J (1976) Clinical use of buprenorphine in chronic administration. Acta Anaesthesiol Belg 27:187\u2013191","journal-title":"Acta Anaesthesiol Belg"},{"key":"449_CR3","first-page":"620","volume-title":"Trait\u00e9 d\u2019addictologie","author":"M Auriacombe","year":"2008","unstructured":"Auriacombe M, Fatseas M, Daulouede JP (2008) Therapeutiques de substitution aux opiac\u00e9s: m\u00e9thadone orale et bupr\u00e9norphine sublinguale. In: Reynaud M (ed) Trait\u00e9 d\u2019addictologie, 2nd edn. Medecine-Sciences Flammarion, Paris, pp 620\u2013644","edition":"2"},{"key":"449_CR4","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/clpt.1994.71","volume":"55","author":"SL Walsh","year":"1994","unstructured":"Walsh SL, Preston KL, Stitzer ML, Cone EJ, Bigelow GE (1994) Clinical pharmacology of buprenorphine: ceiling effects at high doses. Clin Pharmacol Ther 55:569\u2013580","journal-title":"Clin Pharmacol Ther"},{"key":"449_CR5","first-page":"1","volume":"60","author":"I Obradovic","year":"2008","unstructured":"Obradovic I, Canarelli T (2008) The initial prescription of methadone in health establishments. An analysis of medical practices in hospital and penal environments since the introduction of the circular dated January 30, 2002. Tendances 60:1\u20134","journal-title":"Tendances"},{"key":"449_CR6","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0379-0738(01)00454-6","volume":"121","author":"P Kintz","year":"2001","unstructured":"Kintz P (2001) Deaths involving buprenorphine: a compendium of French cases. Forensic Sci Int 121:65\u201369","journal-title":"Forensic Sci Int"},{"key":"449_CR7","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/S0009-9120(02)00304-1","volume":"35","author":"P Kintz","year":"2002","unstructured":"Kintz P (2002) A new series of 13 buprenorphine-related deaths. Clin Biochem 35:513\u2013516","journal-title":"Clin Biochem"},{"key":"449_CR8","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.forsciint.2006.03.037","volume":"162","author":"SH Lai","year":"2006","unstructured":"Lai SH, Yao YJ, Lo DS (2006) A survey of buprenorphine related deaths in Singapore. Forensic Sci Int 162:80\u201386","journal-title":"Forensic Sci Int"},{"key":"449_CR9","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1093\/jat\/22.6.430","volume":"22","author":"A Tracqui","year":"1998","unstructured":"Tracqui A, Kintz P, Ludes B (1998) Buprenorphine-related deaths among drug addicts in France: a report on 20 fatalities. J Anal Toxicol 22:430\u2013434","journal-title":"J Anal Toxicol"},{"key":"449_CR10","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1046\/j.1360-0443.2001.9645978.x","volume":"96","author":"M Valenciano","year":"2001","unstructured":"Valenciano M, Emmanuelli J, Lert F (2001) Unsafe injecting practices among attendees of syringe exchange programmes in France. Addiction 96:597\u2013606","journal-title":"Addiction"},{"key":"449_CR11","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1046\/j.1360-0443.1998.93913859.x","volume":"93","author":"M Reynaud","year":"1998","unstructured":"Reynaud M, Petit G, Potard D, Courty P (1998) Six deaths linked to concomitant use of buprenorphine and benzodiazepines. Addiction 93:1385\u20131392","journal-title":"Addiction"},{"key":"449_CR12","unstructured":"Minist\u00e8re de la Justice. Note SJ-06-240-AB3\/04.08.06 relative \u00e0 la tarification des analyses toxicologiques"},{"key":"449_CR13","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1111\/j.1360-0443.2004.00790.x","volume":"99","author":"S Pirnay","year":"2004","unstructured":"Pirnay S, Borron SW, Giudicelli CP, Tourneau J, Baud FJ, Ricordel Y (2004) A critical review of the causes of death among post-mortem toxicological investigations: analysis of 34 buprenorphine-associated and 35 methadone-associated deaths. Addiction 99:978\u2013988","journal-title":"Addiction"},{"key":"449_CR14","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.reaurg.2004.03.018","volume":"13","author":"B Megarbane","year":"2004","unstructured":"Megarbane B, Deye N, Baud FJ (2004) Contribution of experimental data to respiratory depression induced by psychotropic drugs. R\u00e9animation 13:334\u2013342","journal-title":"R\u00e9animation"},{"key":"449_CR15","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/S0022-3565(24)36604-2","volume":"281","author":"M Ohtani","year":"1996","unstructured":"Ohtani M, Kotaki H, Nishitateno K, Sawada Y, Iga T (1996) Kinetics of respiratory depression in rats induced by buprenorphine ans its metabolite, norbuprenorphine. J Pharmacol Exp Ther 281:428\u2013433","journal-title":"J Pharmacol Exp Ther"},{"key":"449_CR16","doi-asserted-by":"crossref","first-page":"79","DOI":"10.2165\/00139709-200625020-00002","volume":"25","author":"B Megarbane","year":"2006","unstructured":"Megarbane B, Hreiche R, Pirnay S, Marie N, Baud FJ (2006) Does high-dose buprenorphine cause respiratory depression? Possible mechanisms and therapeutic consequences. Toxicol Rev 25:79\u201385","journal-title":"Toxicol Rev"},{"key":"449_CR17","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1093\/toxsci\/kfn163","volume":"106","author":"S Pirnay","year":"2008","unstructured":"Pirnay S, Megarbane B, Decleves X, Risede P, Borron SW, Bouchonnet S, Perrin B, Debray M, Milan N, Duarte T, Ricordel Y, Baud FJ (2008) Buprenorphine alters desmethylflunitrazepam disposition and flunitrazepam toxicity in rats. Toxicol Sci 106:64\u201373","journal-title":"Toxicol Sci"},{"key":"449_CR18","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1520\/JFS16081J","volume":"43","author":"MD Robertson","year":"1998","unstructured":"Robertson MD, Drummer OH (1998) Stability of nitrobenzodiazepines in postmortem blood. Forensic Sci 43:5\u20138","journal-title":"Forensic Sci"},{"key":"449_CR19","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1016\/S0024-3205(97)00160-4","volume":"60","author":"C Iribarne","year":"1997","unstructured":"Iribarne C, Picard D, Dreano Y, Bail JP, Berthou F (1997) Involvement of cytochrome P450 3A4 in N-dealkylation of buprenorphine in human liver microsomes. Life Sci 60:1953\u20131964","journal-title":"Life Sci"},{"key":"449_CR20","first-page":"818","volume":"26","author":"K Kobayashi","year":"1998","unstructured":"Kobayashi K, Yamamoto T, Chiba K, Tani M, Shimada N, Ishizaki T, Kuroiwa Y (1998) Human buprenorphine N-dealkylation is catalysed by cytochrome P450 3A4. Drug Metab Dispos 26:818\u2013821","journal-title":"Drug Metab Dispos"},{"key":"449_CR21","doi-asserted-by":"crossref","first-page":"17","DOI":"10.2165\/00003088-199937010-00002","volume":"37","author":"I Tegeder","year":"1999","unstructured":"Tegeder I, L\u00f6tsch J, Geisslinger G (1999) Pharmacokinetics of opioids in liver disease. Clin Pharmacokinet 37:17\u201340","journal-title":"Clin Pharmacokinet"},{"key":"449_CR22","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1345\/aph.1L628","volume":"43","author":"H Peyriere","year":"2009","unstructured":"Peyriere H, Tatem L, Bories C, Pageaux GP, Blayac JP, Larrey D (2009) Hepatitis after intravenous injection of sublingual buprenorphine in acute hepatitis C carriers: report of two cases of disappearance of viral replication after acute hepatitis. Ann Pharmacother 43:973\u2013977","journal-title":"Ann Pharmacother"},{"key":"449_CR23","doi-asserted-by":"crossref","first-page":"e8","DOI":"10.1016\/j.dld.2007.12.014","volume":"41","author":"M Zuin","year":"2009","unstructured":"Zuin M, Giorgini A, Selmi C, Battezzati PM, Cocchi CA, Crosignani A, Benetti A, Invernizzi P, Podda M (2009) Acute liver and renal failure during treatment with buprenorphine at therapeutic dose. Dig Liver Dis 41:e8\u2013e10","journal-title":"Dig Liver Dis"},{"key":"449_CR24","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1093\/jat\/27.7.527","volume":"27","author":"P Kintz","year":"2003","unstructured":"Kintz P, Villain M, Tracqui A, Cirimele V, Ludes B (2003) Buprenorphine in drug-facilitated sexual abuse: a fatal case involving a 14-year-old boy. J Anal Toxicol 27:527\u2013529","journal-title":"J Anal Toxicol"},{"key":"449_CR25","first-page":"351","volume-title":"DSM-IV-TRTM mental disorders. Diagnosis, etiology and treatment","author":"MB First","year":"2004","unstructured":"First MB, Tasman A (2004) DSM-IV-TRTM mental disorders. Diagnosis, etiology and treatment. Wiley, Chichester, pp 351\u2013372"},{"key":"449_CR26","unstructured":"Escots S, Fahet G (2004) Usages non substitutifs de la buprenorphine haut dosage. Investigation men\u00e9e en France en 2002\u20132003. Observatoire Fran\u00e7ais des Drogues et des Toxicomanies. http:\/\/www.ofdt.fr\/BDD\/publications\/docs\/epfxsek6.pdf"}],"container-title":["International Journal of Legal Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00414-010-0449-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00414-010-0449-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00414-010-0449-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T21:27:29Z","timestamp":1740000449000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00414-010-0449-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4,6]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["449"],"URL":"https:\/\/doi.org\/10.1007\/s00414-010-0449-1","relation":{},"ISSN":["0937-9827","1437-1596"],"issn-type":[{"type":"print","value":"0937-9827"},{"type":"electronic","value":"1437-1596"}],"subject":[],"published":{"date-parts":[[2010,4,6]]}}}