{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T13:23:44Z","timestamp":1783517024544,"version":"3.55.0"},"reference-count":114,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Department of Anti-Drug Policies, of the Presidency of the Council of Ministers, Italy","award":["Effects of NPS: development of a multicentre research for the information enhancement of the Early Warning System"],"award-info":[{"award-number":["Effects of NPS: development of a multicentre research for the information enhancement of the Early Warning System"]}]},{"DOI":"10.13039\/501100007109","name":"Universit\u00e0 degli Studi di Ferrara","doi-asserted-by":"publisher","award":["FAR 2017"],"award-info":[{"award-number":["FAR 2017"]}],"id":[{"id":"10.13039\/501100007109","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007109","name":"Universit\u00e0 degli Studi di Ferrara","doi-asserted-by":"publisher","award":["FAR 2016"],"award-info":[{"award-number":["FAR 2016"]}],"id":[{"id":"10.13039\/501100007109","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Italian Ministry of Education, University and Research","award":["RBFR12LDOW"],"award-info":[{"award-number":["RBFR12LDOW"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Legal Med"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1007\/s00414-020-02302-3","type":"journal-article","created":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:02:21Z","timestamp":1588291341000},"page":"1695-1711","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Methiopropamine and its acute behavioral effects in mice: is there a gray zone in new psychoactive substances users?"],"prefix":"10.1007","volume":"134","author":[{"given":"Fabio","family":"De-Giorgio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrine","family":"Bilel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micaela","family":"Tirri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaella","family":"Arf\u00e8","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Trapella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristian","family":"Camuto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Foti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Frisoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margherita","family":"Neri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Botr\u00e8","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Marti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,5,1]]},"reference":[{"key":"2302_CR1","doi-asserted-by":"publisher","unstructured":"Schifano F, Napoletano F, Arillotta D, Zangani C, Gilgar L, Guirguis A, Corkery JM, Vento A (2019, 2019) The clinical challenges of synthetic cathinones. Br J Clin Pharmacol. https:\/\/doi.org\/10.1111\/bcp.14132 [Epub ahead of print] PubMed PMID: 31674690","DOI":"10.1111\/bcp.14132"},{"key":"2302_CR2","doi-asserted-by":"publisher","unstructured":"Lehmann S, Kieliba T, Thevis M, Rothschild MA, Mercer-Chalmers-Bender K (2019, 2019) Fatalities associated with NPS stimulants in the Greater Cologne area. Int J Legal Med. https:\/\/doi.org\/10.1007\/s00414-019-02193-z [Epub ahead of print] PubMed PMID: 31735981","DOI":"10.1007\/s00414-019-02193-z"},{"issue":"1","key":"2302_CR3","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1007\/s00414-018-1882-9","volume":"133","author":"S Iwersen-Bergmann","year":"2019","unstructured":"Iwersen-Bergmann S, Lehmann S, Heinemann A, Schr\u00f6der C, M\u00fcller A, Jungen H, Andresen-Streichert H, Pueschel K, Vidal C, Mercer-Chalmers-Bender K (2019) Mass poisoning with NPS: 2C-E and Bromo-DragonFly. Int J Legal Med 133(1):123\u2013129. https:\/\/doi.org\/10.1007\/s00414-018-1882-9 Erratum in: Int J Legal Med. 2018 Jul 21; PubMed PMID: 29959557","journal-title":"Int J Legal Med"},{"issue":"1","key":"2302_CR4","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1007\/s00414-018-1969-3","volume":"133","author":"C Richeval","year":"2019","unstructured":"Richeval C, Gaulier JM, Romeuf L, Allorge D, Gaillard Y (2019) Case report: relevance of metabolite identification to detect new synthetic opioid intoxications illustrated by U-47700. Int J Legal Med 133(1):133\u2013142. https:\/\/doi.org\/10.1007\/s00414-018-1969-3 PubMed PMID: 30443678","journal-title":"Int J Legal Med"},{"issue":"2","key":"2302_CR5","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1007\/s00414-018-1901-x","volume":"133","author":"P Kintz","year":"2019","unstructured":"Kintz P, Ameline A, Walch A, Farrugia A, Raul JS (2019) Murdered while under the influence of 3-MeO-PCP. Int J Legal Med 133(2):475\u2013478. https:\/\/doi.org\/10.1007\/s00414-018-1901-x PubMed PMID: 30039274","journal-title":"Int J Legal Med"},{"key":"2302_CR6","unstructured":"New psychoactive substances in Europe. An update from the EU early warning system. European Monitoring Centre for Drugs and Drugs Addiction. March 2015"},{"issue":"6","key":"2302_CR7","doi-asserted-by":"publisher","first-page":"1543","DOI":"10.1007\/s00414-017-1648-9","volume":"131","author":"B Barcel\u00f3","year":"2017","unstructured":"Barcel\u00f3 B, Gomila I, Rotolo MC, Marchei E, Kyriakou C, Pichini S, Roset C, Elorza M\u00c1, Busard\u00f2 FP (2017) Intoxication caused by new psychostimulants: analytical methods to disclose acute and chronic use of benzofurans and ethylphenidate. Int J Legal Med 131(6):1543\u20131553. https:\/\/doi.org\/10.1007\/s00414-017-1648-9 PubMed PMID: 28710651","journal-title":"Int J Legal Med"},{"issue":"5","key":"2302_CR8","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1007\/s00414-015-1150-1","volume":"129","author":"A Maas","year":"2015","unstructured":"Maas A, Wippich C, Madea B, Hess C (2015) Driving under the influence of synthetic phenethylamines: a case series. Int J Legal Med 129(5):997\u20131003. https:\/\/doi.org\/10.1007\/s00414-015-1150-1 PubMed PMID: 25618172","journal-title":"Int J Legal Med"},{"issue":"3","key":"2302_CR9","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1016\/j.annemergmed.2017.07.482","volume":"71","author":"L Hondebrink","year":"2018","unstructured":"Hondebrink L, Nugteren-van Lonkhuyzen JJ, Rietjens SJ, Brunt TM, Venhuis B, Soerdjbalie-Maikoe V, Smink BE, van Riel AJHP, de Vries I (2018) Fatalities, cerebral hemorrhage, and severe cardiovascular toxicity after exposure to the new psychoactive substance 4-fluoroamphetamine: a prospective cohort study. Ann Emerg Med 71(3):294\u2013305. https:\/\/doi.org\/10.1016\/j.annemergmed.2017.07.482 PubMed PMID: 28969928","journal-title":"Ann Emerg Med"},{"issue":"3","key":"2302_CR10","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1021\/ja01255a001","volume":"64","author":"FF Blicke","year":"1942","unstructured":"Blicke FF, Burckhalter JH (1942) \u03b1-Thienylaminoalkanes. J Am Chem Soc 64(3):477\u2013480","journal-title":"J Am Chem Soc"},{"issue":"1-3","key":"2302_CR11","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.ejphar.2012.12.006","volume":"700","author":"L Iversen","year":"2013","unstructured":"Iversen L, Gibbons S, Treble R, Setola V, Huang XP, Roth BL (2013) Neurochemical profiles of some novel psychoactive substances. Eur J Pharmacol 700(1-3):147\u2013151. https:\/\/doi.org\/10.1016\/j.ejphar.2012.12.006 PubMed PMID: 23261499; PubMed Central PMCID: PMC3582025","journal-title":"Eur J Pharmacol"},{"key":"2302_CR12","unstructured":"38th ECDD (2016) Agenda item 4.8. Methiopropamine (MPA) critical review report agenda item 4.8 expert. https:\/\/www.who.int\/medicines\/access\/controlled-substances\/4.8_MPA_CritReview.pdf?ua=1"},{"key":"2302_CR13","unstructured":"Methiopropamine (MPA): a review of the evidence of use and harm. Further advice\u2014June 2017 https:\/\/assets.publishing.service.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/619755\/ACMD_s_further_advice_on_methiopropamine_June_2017.pdf"},{"issue":"2","key":"2302_CR14","first-page":"53","volume":"8","author":"JF Casale","year":"2011","unstructured":"Casale JF, Hays PA (2011) Methiopropamine: an analytical profile. Microgram J 8(2):53\u201357","journal-title":"Microgram J"},{"issue":"3","key":"2302_CR15","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1007\/s13181-014-0399-y","volume":"10","author":"HM Lee","year":"2014","unstructured":"Lee HM, Wood DM, Hudson S, Archer JR, Dargan PI (2014) Acute toxicity associated with analytically confirmed recreational use of methiopropamine (1-(thiophen-2-yl)-2-methylaminopropane). J Med Toxicol. 10(3):299\u2013302. https:\/\/doi.org\/10.1007\/s13181-014-0399-y PubMed PMID: 24706157; PubMed Central PMCID: PMC4141929","journal-title":"J Med Toxicol."},{"issue":"3","key":"2302_CR16","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1097\/PAF.0000000000000170","volume":"36","author":"S Anne","year":"2015","unstructured":"Anne S, Tse R, Cala AD (2015) A fatal case of isolated methiopropamine (1-(thiophen-2-yl)-2-methylaminopropane) toxicity: a case report. Am J Forensic Med Pathol 36(3):205\u2013206. https:\/\/doi.org\/10.1097\/PAF.0000000000000170 PubMed PMID: 26049970","journal-title":"Am J Forensic Med Pathol"},{"issue":"1","key":"2302_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/15389588.2015.1036157","volume":"17","author":"SS Tuv","year":"2016","unstructured":"Tuv SS, Bergh MS, Vindenes V, Karinen R (2016) Methiopropamine in blood samples from drivers suspected of being under the influence of drugs. Traffic Inj Prev. 17(1):1\u20134. https:\/\/doi.org\/10.1080\/15389588.2015.1036157 PubMed PMID: 25874580","journal-title":"Traffic Inj Prev."},{"issue":"9","key":"2302_CR18","first-page":"758","volume":"40","author":"A Daveluy","year":"2016","unstructured":"Daveluy A, Castaing N, Cherifi H, Richeval C, Humbert L, Faure I, Labadie M, Allorge D, Haramburu F, Molimard M, Titier K (2016) Acute methiopropamine intoxication after \u201csynthacaine\u201d consumption. J Anal Toxicol 40(9):758\u2013760 PubMed PMID: 27474360","journal-title":"J Anal Toxicol"},{"issue":"3","key":"2302_CR19","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1002\/dta.2232","volume":"10","author":"SMR Wille","year":"2018","unstructured":"Wille SMR, Richeval C, Nachon-Phanithavong M, Gaulier JM, Di Fazio V, Humbert L, Samyn N, Allorge D (2018) Prevalence of new psychoactive substances and prescription drugs in the Belgian driving under the influence of drugs population. Drug Test Anal. 10(3):539\u2013547. https:\/\/doi.org\/10.1002\/dta.2232 PubMed PMID: 28640970","journal-title":"Drug Test Anal."},{"issue":"6","key":"2302_CR20","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1177\/0004563218767462","volume":"55","author":"LT Ford","year":"2018","unstructured":"Ford LT, Berg JD (2018) Analytical evidence to show letters impregnated with novel psychoactive substances are a means of getting drugs to inmates within the UK prison service. Ann Clin Biochem 55(6):673\u2013678. https:\/\/doi.org\/10.1177\/0004563218767462 PubMed PMID: 29534614","journal-title":"Ann Clin Biochem"},{"issue":"3","key":"2302_CR21","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1007\/s00414-018-1891-8","volume":"133","author":"F Foti","year":"2019","unstructured":"Foti F, Marti M, Ossato A, Bilel S, Sangiorgi E, Botr\u00e8 F, Cerbelli B, Baldi A, De-Giorgio F (2019) Phenotypic effects of chronic and acute use of methiopropamine in a mouse model. Int J Legal Med 133(3):811\u2013820. https:\/\/doi.org\/10.1007\/s00414-018-1891-8 PubMed PMID: 30056621","journal-title":"Int J Legal Med"},{"key":"2302_CR22","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1016\/j.bbr.2016.05.060","volume":"311","author":"HS Yoon","year":"2016","unstructured":"Yoon HS, Cai WT, Lee YH, Park KT, Lee YS, Kim JH (2016) The expression of methiopropamine-induced locomotor sensitization requires dopamine D2, but not D1, receptor activation in the rat. Behav Brain Res 311:403\u2013407. https:\/\/doi.org\/10.1016\/j.bbr.2016.05.060 PubMed PMID: 27265782","journal-title":"Behav Brain Res"},{"key":"2302_CR23","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1016\/j.neuroscience.2015.05.021","volume":"300","author":"A Ossato","year":"2015","unstructured":"Ossato A, Vigolo A, Trapella C, Seri C, Rimondo C, Serpelloni G, Marti M (2015) JWH-018 impairs sensorimotor functions in mice. Neuroscience 300:174\u2013188. https:\/\/doi.org\/10.1016\/j.neuroscience.2015.05.021 PubMed PMID: 25987201","journal-title":"Neuroscience"},{"key":"2302_CR24","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.neuropharm.2018.08.017","volume":"141","author":"A Ossato","year":"2018","unstructured":"Ossato A, Bilel S, Gregori A, Talarico A, Trapella C, Gaudio RM, De-Giorgio F, Tagliaro F, Neri M, Fattore L, Marti M (2018) Neurological, sensorimotor and cardiorespiratory alterations induced by methoxetamine, ketamine and phencyclidine in mice. Neuropharmacology. 141:167\u2013180. https:\/\/doi.org\/10.1016\/j.neuropharm.2018.08.017 PubMed PMID: 30165078","journal-title":"Neuropharmacology."},{"key":"2302_CR25","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.neuropharm.2015.02.008","volume":"95","author":"A Vigolo","year":"2015","unstructured":"Vigolo A, Ossato A, Trapella C, Vincenzi F, Rimondo C, Seri C, Varani K, Serpelloni G, Marti M (2015) Novel halogenated derivates of JWH-018: behavioral and binding studies in mice. Neuropharmacology. 95:68\u201382. https:\/\/doi.org\/10.1016\/j.neuropharm.2015.02.008 PubMed PMID: 25769232","journal-title":"Neuropharmacology."},{"issue":"21\u201322","key":"2302_CR26","doi-asserted-by":"crossref","first-page":"3685","DOI":"10.1007\/s00213-016-4402-y","volume":"233","author":"I Canazza","year":"2016","unstructured":"Canazza I, Ossato A, Trapella C, Fantinati A, De Luca MA, Margiani G, Vincenzi F, Rimondo C, Di Rosa F, Gregori A, Varani K, Borea PA, Serpelloni G, Marti M (2016) Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on \u201ctetrad\u201d, sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies. Psychopharmacology 233(21\u201322):3685\u20133709 PubMed PMID: 27527584","journal-title":"Psychopharmacology"},{"key":"2302_CR27","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.3389\/fnins.2019.01163","volume":"13","author":"S Bilel","year":"2019","unstructured":"Bilel S, Tirri M, Arf\u00e8 R, Stopponi S, Soverchia L, Ciccocioppo R, Frisoni P, Strano-Rossi S, Miliano C, De-Giorgio F, Serpelloni G, Fantinati A, De Luca MA, Neri M, Marti M (2019) Pharmacological and behavioral effects of the synthetic cannabinoid AKB48 in rats. Front Neurosci 13:1163. https:\/\/doi.org\/10.3389\/fnins.2019.01163 eCollection 2019. PubMed PMID: 31736697; PubMed Central PMCID: PMC6831561","journal-title":"Front Neurosci"},{"key":"2302_CR28","doi-asserted-by":"publisher","first-page":"130","DOI":"10.3389\/fpsyt.2017.00130","volume":"8","author":"A Ossato","year":"2017","unstructured":"Ossato A, Uccelli L, Bilel S, Canazza I, Di Domenico G, Pasquali M, Pupillo G, De Luca MA, Boschi A, Vincenzi F, Rimondo C, Beggiato S, Ferraro L, Varani K, Borea PA, Serpelloni G, De-Giorgio F, Marti M (2017) Psychostimulant effect of the synthetic cannabinoid JWH-018 and AKB48: behavioral, neurochemical, and dopamine transporter scan imaging studies in mice. Front Psych 8:130. https:\/\/doi.org\/10.3389\/fpsyt.2017.00130 eCollection 2017. PubMed PMID: 28824464; PubMed Central PMCID: PMC5543288","journal-title":"Front Psych"},{"key":"2302_CR29","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.pnpbp.2016.01.007","volume":"67","author":"A Ossato","year":"2016","unstructured":"Ossato A, Canazza I, Trapella C, Vincenzi F, De Luca MA, Rimondo C, Varani K, Borea PA, Serpelloni G, Marti M (2016) Effect of JWH-250, JWH-073 and their interaction on \u201ctetrad\u201d, sensorimotor, neurological and neurochemical responses in mice. Prog Neuropsychopharmacol Biol Psych 67:31\u201350. https:\/\/doi.org\/10.1016\/j.pnpbp.2016.01.007 PubMed PMID: 26780169","journal-title":"Prog Neuropsychopharmacol Biol Psych"},{"issue":"2","key":"2302_CR30","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0301-0082(98)00098-7","volume":"59","author":"M Koch","year":"1999","unstructured":"Koch M (1999) The neurobiology of startle. Prog Neurobiol 59(2):107\u2013128 PubMed PMID: 10463792","journal-title":"Prog Neurobiol"},{"issue":"1","key":"2302_CR31","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/s11419-018-0444-7","volume":"37","author":"M Marti","year":"2019","unstructured":"Marti M, Neri M, Bilel S, Di Paolo M, La Russa R, Ossato A, Turillazzi E (2019) MDMA alone affects sensorimotor and prepulse inhibition responses in mice and rats. Tips in the debate on potential MDMA unsafety in human activity. Forensic Toxicol 37(1):132\u2013144","journal-title":"Forensic Toxicol"},{"key":"2302_CR32","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.bbr.2014.07.016","volume":"277","author":"AL Halberstadt","year":"2015","unstructured":"Halberstadt AL (2015) Recent advances in the neuropsychopharmacology of serotonergic hallucinogens. Behav Brain Res 277:99\u2013120. https:\/\/doi.org\/10.1016\/j.bbr.2014.07.016 PubMed PMID: 25036425; PubMed Central PMCID: PMC4642895","journal-title":"Behav Brain Res"},{"key":"2302_CR33","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.neuropharm.2018.02.033","volume":"142","author":"JS Elmore","year":"2018","unstructured":"Elmore JS, Decker AM, Sulima A, Rice KC, Partilla JS, Blough BE, Baumann MH (2018) Comparative neuropharmacology of N-(2-methoxybenzyl)-2,5-dimethoxyphenethylamine (NBOMe) hallucinogens and their 2C counterparts in male rats. Neuropharmacology. 142:240\u2013250. https:\/\/doi.org\/10.1016\/j.neuropharm.2018.02.033 PubMed PMID: 29501528; PubMed Central PMCID: PMC6119551","journal-title":"Neuropharmacology."},{"key":"2302_CR34","unstructured":"Canazza I, Ossato A, Trapella C, Seri C, Rimondo C, Serpelloni G, Marti M, (2015) 2C-B and 25I-NBOMe impair sensorimotor functions in mice. Proceedings from Italian Society of Pharmacology \u201caddictive disorders: from neurobiology to novel therapeutic strategies\u201d P.9. Palermo, Italy, March 27th-28th"},{"issue":"10","key":"2302_CR35","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1002\/dneu.22375","volume":"76","author":"FM Lambert","year":"2016","unstructured":"Lambert FM, Bras H, Cardoit L, Vinay L, Coulon P, Glover JC (2016) Early postnatal maturation in vestibulospinal pathways involved in neck and forelimb motor control. Dev Neurobiol 76(10):1061\u20131077. https:\/\/doi.org\/10.1002\/dneu.22375 PubMed PMID: 26724676","journal-title":"Dev Neurobiol"},{"issue":"1\u20132","key":"2302_CR36","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0165-0173(98)00024-1","volume":"28","author":"F Clarac","year":"1998","unstructured":"Clarac F, Vinay L, Cazalets JR, Fady JC, Jamon M (1998) Role of gravity in the development of posture and locomotion in the neonatal rat. Brain Res Brain Res Rev 28(1\u20132):35\u201343 PubMed PMID: 9795120","journal-title":"Brain Res Brain Res Rev"},{"key":"2302_CR37","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.neuroscience.2011.10.054","volume":"200","author":"AP Tosolini","year":"2012","unstructured":"Tosolini AP, Morris R (2012) Spatial characterization of the motor neuron columns supplying the rat forelimb. Neuroscience 200:19\u201330. https:\/\/doi.org\/10.1016\/j.neuroscience.2011.10.054 PubMed PMID: 22100785","journal-title":"Neuroscience"},{"key":"2302_CR38","doi-asserted-by":"publisher","first-page":"58","DOI":"10.3389\/fneur.2013.00058","volume":"4","author":"AP Tosolini","year":"2013","unstructured":"Tosolini AP, Mohan R, Morris R (2013) Targeting the full length of the motor end plate regions in the mouse forelimb increases the uptake of fluoro-gold into corresponding spinal cord motor neurons. Front Neurol 4:58. https:\/\/doi.org\/10.3389\/fneur.2013.00058 eCollection 2013. PubMed PMID: 23730296; PubMed Central PMCID: PMC3657688","journal-title":"Front Neurol"},{"key":"2302_CR39","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1146\/annurev.neuro.31.060407.125555","volume":"31","author":"DE Angelaki","year":"2008","unstructured":"Angelaki DE, Cullen KE (2008) Vestibular system: the many facets of a multimodal sense. Annu Rev Neurosci 31:125\u2013150. https:\/\/doi.org\/10.1146\/annurev.neuro.31.060407.125555 PubMed PMID: 18338968","journal-title":"Annu Rev Neurosci"},{"issue":"3","key":"2302_CR40","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.tins.2011.12.001","volume":"35","author":"KE Cullen","year":"2012","unstructured":"Cullen KE (2012) The vestibular system: multimodal integration and encoding of self-motion for motor control. Trends Neurosci 35(3):185\u2013196. https:\/\/doi.org\/10.1016\/j.tins.2011.12.001 PubMed PMID: 22245372; PubMed Central PMCID: PMC4000483","journal-title":"Trends Neurosci"},{"issue":"Pt 1","key":"2302_CR41","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1242\/jeb.199.1.201","volume":"199","author":"AS Etienne","year":"1996","unstructured":"Etienne AS, Maurer R, S\u00e9guinot V (1996) Path integration in mammals and its interaction with visual landmarks. J Exp Biol 199(Pt 1):201\u2013209 PubMed PMID: 8576691","journal-title":"J Exp Biol"},{"issue":"1","key":"2302_CR42","doi-asserted-by":"publisher","first-page":"3944","DOI":"10.1038\/s41598-017-04273-9","volume":"7","author":"R Wakita","year":"2017","unstructured":"Wakita R, Tanabe S, Tabei K, Funaki A, Inoshita T, Hirano T (2017) Differential regulations of vestibulo-ocular reflex and optokinetic response by \u03b2- and \u03b12-adrenergic receptors in the cerebellar flocculus. Sci Rep 7(1):3944. https:\/\/doi.org\/10.1038\/s41598-017-04273-9 PubMed PMID: 28638085; PubMed Central PMCID: PMC5479797","journal-title":"Sci Rep"},{"issue":"1","key":"2302_CR43","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0306-4522(93)90389-W","volume":"54","author":"M Eybalin","year":"1993","unstructured":"Eybalin M, Charachon G, Renard N (1993) Dopaminergic lateral efferent innervation of the Guinea-pig cochlea: immunoelectron microscopy of catecholamine-synthesizing enzymes and effect of 6-hydroxydopamine. Neuroscience. 54(1):133\u2013142 PubMed PMID: 8100046","journal-title":"Neuroscience."},{"issue":"1","key":"2302_CR44","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0169-328X(96)00261-6","volume":"44","author":"AA Karadaghy","year":"1997","unstructured":"Karadaghy AA, Lasak JM, Chomchai JS, Khan KM, Drescher MJ, Drescher DG (1997) Quantitative analysis of dopamine receptor messages in the mouse cochlea. Brain Res Mol Brain Res 44(1):151\u2013156 PubMed PMID: 9030711","journal-title":"Brain Res Mol Brain Res"},{"issue":"3","key":"2302_CR45","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/cne.21050","volume":"498","author":"KN Darrow","year":"2006","unstructured":"Darrow KN, Simons EJ, Dodds L, Liberman MC (2006) Dopaminergic innervation of the mouse inner ear: evidence for a separate cytochemical group of cochlear efferent fibers. J Comp Neurol 498(3):403\u2013414 PubMed PMID: 16871528; PubMed Central PMCID: PMC1805779","journal-title":"J Comp Neurol"},{"issue":"3","key":"2302_CR46","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.neulet.2006.01.063","volume":"399","author":"T Inoue","year":"2006","unstructured":"Inoue T, Matsubara A, Maruya S, Yamamoto Y, Namba A, Sasaki A, Shinkawa H (2006) Localization of dopamine receptor subtypes in the rat spiral ganglion. Neurosci Lett 399(3):226\u2013229 PubMed PMID: 16490310","journal-title":"Neurosci Lett"},{"issue":"3","key":"2302_CR47","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.neuroscience.2005.10.044","volume":"137","author":"X Niu","year":"2006","unstructured":"Niu X, Canlon B (2006) The signal transduction pathway for the dopamine D1 receptor in the guinea-pig cochlea. Neuroscience. 137(3):981\u2013990 PubMed PMID: 16330149","journal-title":"Neuroscience."},{"issue":"1","key":"2302_CR48","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1523\/JNEUROSCI.4720-11.2012","volume":"32","author":"SF Maison","year":"2012","unstructured":"Maison SF, Liu XP, Eatock RA, Sibley DR, Grandy DK, Liberman MC (2012) Dopaminergic signaling in the cochlea: receptor expression patterns and deletion phenotypes. J Neurosci 32(1):344\u2013355. https:\/\/doi.org\/10.1523\/JNEUROSCI.4720-11.2012 PubMed PMID: 22219295; PubMed Central PMCID: PMC3313790","journal-title":"J Neurosci"},{"issue":"4","key":"2302_CR49","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1016\/j.neuroscience.2010.09.051","volume":"171","author":"MJ Drescher","year":"2010","unstructured":"Drescher MJ, Cho WJ, Folbe AJ, Selvakumar D, Kewson DT, Abu-Hamdan MD, Oh CK, Ramakrishnan NA, Hatfield JS, Khan KM, Anne S, Harpool EC, Drescher DG (2010) An adenylyl cyclase signaling pathway predicts direct dopaminergic input to vestibular hair cells. Neuroscience 171(4):1054\u20131074. https:\/\/doi.org\/10.1016\/j.neuroscience.2010.09.051 PubMed PMID: 20883745; PubMed Central PMCID: PMC3025754","journal-title":"Neuroscience"},{"issue":"6","key":"2302_CR50","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1046\/j.0953-816x.2001.01721.x","volume":"14","author":"J Ruel","year":"2001","unstructured":"Ruel J, Nouvian R, Gervais d'Aldin C, Pujol R, Eybalin M, Puel JL (2001) Dopamine inhibition of auditory nerve activity in the adult mammalian cochlea. Eur J Neurosci 14(6):977\u2013986 PubMed PMID: 11595036","journal-title":"Eur J Neurosci"},{"issue":"1-2","key":"2302_CR51","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/0378-5955(95)00167-5","volume":"90","author":"C d'Aldin","year":"1995","unstructured":"d'Aldin C, Puel JL, Leducq R, Crambes O, Eybalin M, Pujol R (1995) Effects of a dopaminergic agonist in the guinea pig cochlea. Hear Res 90(1-2):202\u2013211 Erratum in: Hear Res 1997 Jan;103(1-2):225. PubMed PMID: 8974998","journal-title":"Hear Res"},{"key":"2302_CR52","first-page":"47","volume":"40","author":"F Shima","year":"1984","unstructured":"Shima F (1984) Circling behavior depending on striopallidal and vestibular functions. Adv Neurol 40:47\u201354 PubMed PMID: 6695624","journal-title":"Adv Neurol"},{"issue":"1-2","key":"2302_CR53","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/S0006-8993(00)02457-4","volume":"872","author":"H Lai","year":"2000","unstructured":"Lai H, Tsumori T, Shiroyama T, Yokota S, Nakano K, Yasui Y (2000) Morphological evidence for a vestibulo-thalamo-striatal pathway via the parafascicular nucleus in the rat. Brain Res 872(1-2):208\u2013214 PubMed PMID: 10924695","journal-title":"Brain Res"},{"issue":"5","key":"2302_CR54","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1016\/j.neuro.2012.08.003","volume":"33","author":"JA Marusich","year":"2012","unstructured":"Marusich JA, Grant KR, Blough BE, Wiley JL (2012) Effects of synthetic cathinones contained in \u201cbath salts\u201d on motor behavior and a functional observational battery in mice. Neurotoxicology. 33(5):1305\u20131313. https:\/\/doi.org\/10.1016\/j.neuro.2012.08.003 PubMed PMID: 22922498; PubMed Central PMCID: PMC3475178","journal-title":"Neurotoxicology."},{"key":"2302_CR55","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.neuropharm.2014.02.016","volume":"87","author":"JA Marusich","year":"2014","unstructured":"Marusich JA, Antonazzo KR, Wiley JL, Blough BE, Partilla JS, Baumann MH (2014) Pharmacology of novel synthetic stimulants structurally related to the \u201cbath salts\u201d constituent 3,4-methylenedioxypyrovalerone (MDPV). Neuropharmacology. 87:206\u2013213. https:\/\/doi.org\/10.1016\/j.neuropharm.2014.02.016 PubMed PMID: 24594476; PubMed Central PMCID: PMC4152390","journal-title":"Neuropharmacology."},{"issue":"6","key":"2302_CR56","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.1038\/npp.2014.325","volume":"40","author":"K Saha","year":"2015","unstructured":"Saha K, Partilla JS, Lehner KR, Seddik A, Stockner T, Holy M, Sandtner W, Ecker GF, Sitte HH, Baumann MH (2015) \u2018Second-generation\u2019 mephedrone analogs, 4-MEC and 4-MePPP, differentially affect monoamine transporter function. Neuropsychopharmacology. 40(6):1321\u20131331. https:\/\/doi.org\/10.1038\/npp.2014.325 PubMed PMID: 25502630; PubMed Central PMCID: PMC4397398","journal-title":"Neuropsychopharmacology."},{"issue":"4","key":"2302_CR57","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1007\/s12640-017-9769-y","volume":"32","author":"G Giannotti","year":"2017","unstructured":"Giannotti G, Canazza I, Caffino L, Bilel S, Ossato A, Fumagalli F, Marti M (2017) The cathinones MDPV and \u03b1-PVP elicit different behavioral and molecular effects following cute exposure. Neurotox Res 32(4):594\u2013602. https:\/\/doi.org\/10.1007\/s12640-017-9769-y PubMed PMID: 28646469","journal-title":"Neurotox Res"},{"key":"2302_CR58","first-page":"101","volume":"94","author":"LH Gold","year":"1989","unstructured":"Gold LH, Geyer MA, Koob GF (1989) Neurochemical mechanisms involved in behavioral effects of amphetamines and related designer drugs. NIDA Res Monogr 94:101\u2013126 PubMed PMID: 2514360","journal-title":"NIDA Res Monogr"},{"issue":"1-3","key":"2302_CR59","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ejphar.2012.11.020","volume":"698","author":"MH Baumann","year":"2013","unstructured":"Baumann MH, Partilla JS, Lehner KR (2013) Psychoactive \u201cbath salts\u201d: not so soothing. Eur J Pharmacol 698(1-3):1\u20135. https:\/\/doi.org\/10.1016\/j.ejphar.2012.11.020 PubMed PMID: 23178799; PubMed Central PMCID: PMC3537229","journal-title":"Eur J Pharmacol"},{"issue":"Pt 1","key":"2302_CR60","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.brainresbull.2016.04.011","volume":"126","author":"RA Glennon","year":"2016","unstructured":"Glennon RA, Young R (2016) Neurobiology of 3,4-methylenedioxypyrovalerone (MDPV) and \u03b1-pyrrolidinovalerophenone (\u03b1-PVP). Brain Res Bull 126(Pt 1):111\u2013126. https:\/\/doi.org\/10.1016\/j.brainresbull.2016.04.011 PubMed PMID: 27142261; PubMed Central PMCID: PMC5817884","journal-title":"Brain Res Bull"},{"issue":"3","key":"2302_CR61","doi-asserted-by":"crossref","first-page":"407","DOI":"10.2174\/1570159X13666150121225659","volume":"13","author":"M Zaniewska","year":"2015","unstructured":"Zaniewska M, Filip M, Przegalinski E (2015) The involvement of norepinephrine in behaviors related to psychostimulant addiction. Curr Neuropharmacol 13(3):407\u2013418 PubMed PMID: 26411968; PubMed Central PMCID: PMC4812804","journal-title":"Curr Neuropharmacol"},{"issue":"16","key":"2302_CR62","doi-asserted-by":"publisher","first-page":"3045","DOI":"10.1007\/s00213-015-3944-8","volume":"232","author":"SM Aarde","year":"2015","unstructured":"Aarde SM, Creehan KM, Vandewater SA, Dickerson TJ, Taffe MA (2015) In vivo potency and efficacy of the novel cathinone \u03b1-pyrrolidinopentiophenone and 3,4-methylenedioxypyrovalerone: self-administration and locomotor stimulation in male rats. Psychopharmacology 232(16):3045\u20133055. https:\/\/doi.org\/10.1007\/s00213-015-3944-8 PubMed PMID: 25925780; PubMed Central PMCID: PMC4515201","journal-title":"Psychopharmacology"},{"key":"2302_CR63","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.biopsych.2012.09.010","volume":"73","author":"ML Miller","year":"2013","unstructured":"Miller ML, Moreno AY, Aarde SM, Creehan KM, Vandewater SA, Vaillancourt BD, Wright MJ Jr, Janda KD, Taffe MA (2013b) A methamphetamine vaccine attenuates methamphetamine-induced disruptions in thermoregulation and activity in rats. Biol Psychiatry 73:721\u2013728","journal-title":"Biol Psychiatry"},{"issue":"3","key":"2302_CR64","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/s00213-007-1061-z","volume":"198","author":"BJ Myles","year":"2008","unstructured":"Myles BJ, Jarrett LA, Broom SL, Speaker HA, Sabol KE (2008) The effects of methamphetamine on core body temperature in the rat\u2014part 1: chronic treatment and ambient temperature. Psychopharmacology 198(3):301\u2013311. https:\/\/doi.org\/10.1007\/s00213-007-1061-z PubMed PMID: 18438646","journal-title":"Psychopharmacology"},{"issue":"3","key":"2302_CR65","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1007\/s00213-007-1060-0","volume":"198","author":"BJ Myles","year":"2008","unstructured":"Myles BJ, Sabol KE (2008) The effects of methamphetamine on core body temperature in the rat\u2014part 2: an escalating regimen. Psychopharmacology 198(3):313\u2013322. https:\/\/doi.org\/10.1007\/s00213-007-1060-0 PubMed PMID: 18438647","journal-title":"Psychopharmacology"},{"issue":"5","key":"2302_CR66","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1111\/adb.12038","volume":"18","author":"SM Aarde","year":"2013","unstructured":"Aarde SM, Angrish D, Barlow DJ, Wright MJ Jr, Vandewater SA, Creehan KM, Houseknecht KL, Dickerson TJ, Taffe MA (2013) Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats. Addict Biol 18(5):786\u2013799. https:\/\/doi.org\/10.1111\/adb.12038 PubMed PMID: 23363010; PubMed Central PMCID: PMC3641159","journal-title":"Addict Biol"},{"issue":"1-3","key":"2302_CR67","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/j.drugalcdep.2012.07.003","volume":"127","author":"ML Miller","year":"2013","unstructured":"Miller ML, Creehan KM, Angrish D, Barlow DJ, Houseknecht KL, Dickerson TJ, Taffe MA (2013) Changes in ambient temperature differentially alter the thermoregulatory, cardiac and locomotor stimulant effects of 4-methylmethcathinone (mephedrone). Drug Alcohol Depend 127(1-3):248\u2013253. https:\/\/doi.org\/10.1016\/j.drugalcdep.2012.07.003 PubMed PMID: 22832282; PubMed Central PMCID: PMC3491086","journal-title":"Drug Alcohol Depend"},{"issue":"8","key":"2302_CR68","doi-asserted-by":"publisher","first-page":"e44652","DOI":"10.1371\/journal.pone.0044652","volume":"7","author":"MJ Wright Jr","year":"2012","unstructured":"Wright MJ Jr, Angrish D, Aarde SM, Barlow DJ, Buczynski MW, Creehan KM, Vandewater SA, Parsons LH, Houseknecht KL, Dickerson TJ, Taffe MA (2012) Effect of ambient temperature on the thermoregulatory and locomotor stimulant effects of 4-methylmethcathinone in Wistar and Sprague-Dawley rats. PLoS One 7(8):e44652. https:\/\/doi.org\/10.1371\/journal.pone.0044652 PubMed PMID: 22952999; PubMed Central PMCID: PMC3432134","journal-title":"PLoS One"},{"issue":"4","key":"2302_CR69","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1111\/j.1476-5381.1979.tb08707.x","volume":"67","author":"B Cox","year":"1979","unstructured":"Cox B, Lee TF (1979) Evidence for an endogenous dopamine-mediated hypothermia in the rat. Br J Pharmacol 67(4):605\u2013610 PubMed PMID: 519109; PubMed Central PMCID: PMC2043903","journal-title":"Br J Pharmacol"},{"key":"2302_CR70","doi-asserted-by":"crossref","first-page":"5086","DOI":"10.1523\/JNEUROSCI.18-13-05086.1998","volume":"18","author":"JE Malberg","year":"1998","unstructured":"Malberg JE, Seiden LS (1998) Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat. J Neurosci 18:5086\u20135094","journal-title":"J Neurosci"},{"issue":"4","key":"2302_CR71","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1111\/j.1476-5381.2012.02236.x","volume":"168","author":"SE Shortall","year":"2013","unstructured":"Shortall SE, Green AR, Swift KM, Fone KC, King MV (2013) Differential effects of cathinone compounds and MDMA on body temperature in the rat, and pharmacological characterization of mephedrone-induced hypothermia. Br J Pharmacol 168(4):966\u2013977. https:\/\/doi.org\/10.1111\/j.1476-5381.2012.02236.x PubMed PMID: 23043631, PubMed Central PMCID: PMC3631384","journal-title":"Br J Pharmacol"},{"issue":"5","key":"2302_CR72","doi-asserted-by":"publisher","first-page":"1192","DOI":"10.1038\/npp.2011.304","volume":"37","author":"MH Baumann","year":"2012","unstructured":"Baumann MH, Ayestas MA Jr, Partilla JS, Sink JR, Shulgin AT, Daley PF, Brandt SD, Rothman RB, Ruoho AE, Cozzi NV (2012) The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue. Neuropsychopharmacology. 37(5):1192\u20131203. https:\/\/doi.org\/10.1038\/npp.2011.304 PubMed PMID: 22169943; PubMed Central PMCID: PMC3306880","journal-title":"Neuropsychopharmacology."},{"issue":"2","key":"2302_CR73","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1124\/jpet.111.184119","volume":"339","author":"GC Hadlock","year":"2011","unstructured":"Hadlock GC, Webb KM, McFadden LM, Chu PW, Ellis JD, Allen SC, Andrenyak DM, Vieira-Brock PL, German CL, Conrad KM, Hoonakker AJ, Gibb JW, Wilkins DG, Hanson GR, Fleckenstein AE (2011) 4-Methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse. J Pharmacol Exp Ther 339(2):530\u2013536. https:\/\/doi.org\/10.1124\/jpet.111.184119 PubMed PMID: 21810934; PubMed Central PMCID: PMC3200001","journal-title":"J Pharmacol Exp Ther"},{"issue":"2","key":"2302_CR74","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0149-7634(85)90052-1","volume":"9","author":"WG Clark","year":"1985","unstructured":"Clark WG, Lipton JM (1985) Changes in body temperature after administration of amino acids, peptides, dopamine, neuroleptics and related agents: II. Neurosci Biobehav Rev 9(2):299\u2013371 PubMed PMID: 2861591","journal-title":"Neurosci Biobehav Rev"},{"issue":"2","key":"2302_CR75","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0149-7634(86)90025-4","volume":"10","author":"WG Clark","year":"1986","unstructured":"Clark WG, Lipton JM (1986) Changes in body temperature after administration of adrenergic and serotonergic agents and related drugs including antidepressants: II. Neurosci Biobehav Rev 10(2):153\u2013220 PubMed PMID: 2942805","journal-title":"Neurosci Biobehav Rev"},{"issue":"6","key":"2302_CR76","first-page":"937","volume":"49","author":"CV Gisolfi","year":"1980","unstructured":"Gisolfi CV, Christman JV (1980) Thermal effects of injecting norepinephrine into hypothalamus of the rat during rest and exercise. J Appl Physiol Respir Environ Exerc Physiol 49(6):937\u2013941 PubMed PMID: 7440300","journal-title":"J Appl Physiol Respir Environ Exerc Physiol"},{"issue":"3","key":"2302_CR77","first-page":"363","volume":"49","author":"CV Gisolfi","year":"1980","unstructured":"Gisolfi CV, Mora F, Bloomfield S, Beattie M, Magnes S (1980) Effects of apomorphine and pimozide on temperature regulation during exercise in the rat. J Appl Physiol Respir Environ Exerc Physiol 49(3):363\u2013366 PubMed PMID: 7204155","journal-title":"J Appl Physiol Respir Environ Exerc Physiol"},{"issue":"2","key":"2302_CR78","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/0006-8993(82)90868-X","volume":"234","author":"SJ Brown","year":"1982","unstructured":"Brown SJ, Gisolfi CV, Mora F (1982) Temperature regulation and dopaminergic systems in the brain: does the substantia nigra play a role? Brain Res 234(2):275\u2013286 PubMed PMID: 7059831","journal-title":"Brain Res"},{"key":"2302_CR79","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1113\/jphysiol.1980.sp013147","volume":"300","author":"B Cox","year":"1980","unstructured":"Cox B, Lee TF (1980) Further evidence for a physiological role for hypothalamic dopamine in thermoregulation in the rat. J Physiol 300:7\u201317 PubMed PMID: 7381796; PubMed Central PMCID: PMC1279340","journal-title":"J Physiol"},{"issue":"10","key":"2302_CR80","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1007\/BF00966597","volume":"16","author":"JL Nunes","year":"1991","unstructured":"Nunes JL, Sharif NA, Michel AD, Whiting RL (1991) Dopamine D2-receptors mediate hypothermia in mice: ICV and IP effects of agonists and antagonists. Neurochem Res 16(10):1167\u20131174 PubMed PMID: 1686637","journal-title":"Neurochem Res"},{"issue":"13","key":"2302_CR81","doi-asserted-by":"crossref","first-page":"4861","DOI":"10.1523\/JNEUROSCI.18-13-04861.1998","volume":"18","author":"F Fumagalli","year":"1998","unstructured":"Fumagalli F, Gainetdinov RR, Valenzano KJ, Caron MG (1998) Role of dopamine transporter in methamphetamine-induced neurotoxicity: evidence from mice lacking the transporter. J Neurosci 18(13):4861\u20134869 PubMed PMID: 9634552; PubMed Central PMCID: PMC6792558","journal-title":"J Neurosci"},{"issue":"7","key":"2302_CR82","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1080\/17461391.2015.1111938","volume":"16","author":"X Zheng","year":"2015","unstructured":"Zheng X, Hasegawa H (2015) Central dopaminergic neurotransmission plays an important role in thermoregulation and performance during endurance exercise. Eur J Sport Sci 16(7):818\u2013828. https:\/\/doi.org\/10.1080\/17461391.2015.1111938 Epub 2015 Nov 19","journal-title":"Eur J Sport Sci"},{"issue":"1","key":"2302_CR83","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/0006-8993(92)90972-C","volume":"591","author":"BN Mallick","year":"1992","unstructured":"Mallick BN, Alam MN (1992) Different types of norepinephrinergic receptors are involved in preoptic area mediated independent modulation of sleep-wakefulness and body temperature. Brain Res 591(1):8\u201319","journal-title":"Brain Res"},{"issue":"6","key":"2302_CR84","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.neuint.2007.02.004","volume":"50","author":"VM Kumar","year":"2007","unstructured":"Kumar VM, Vetrivelan R, Mallick HN (2007) Noradrenergic afferents and receptors in the medial preoptic area: neuroanatomical and neurochemical links between the regulation of sleep and body temperature. Neurochem Int 50(6):783\u2013790 Epub 2007 Feb 27","journal-title":"Neurochem Int"},{"issue":"2","key":"2302_CR85","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1124\/jpet.107.126169","volume":"323","author":"DE Rusyniak","year":"2007","unstructured":"Rusyniak DE, Zaretskaia MV, Zaretsky DV, DiMicco JA (2007) 3,4-Methylenedioxymethamphetamine- and 8-hydroxy-2-di-n-propylamino-tetralin-induced hypothermia: role and location of 5-hydroxytryptamine 1A receptors. J Pharmacol Exp Ther 323(2):477\u2013487 Epub 2007 Aug 16","journal-title":"J Pharmacol Exp Ther"},{"key":"2302_CR86","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.neuroscience.2016.05.057","volume":"338","author":"M Llorca-Torralba","year":"2016","unstructured":"Llorca-Torralba M, Borges G, Neto F, Mico JA, Berrocoso E (2016) Noradrenergic locus coeruleus pathways in pain modulation. Neuroscience 338:93\u2013113. https:\/\/doi.org\/10.1016\/j.neuroscience.2016.05.057 PubMed PMID: 27267247","journal-title":"Neuroscience"},{"issue":"3","key":"2302_CR87","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1124\/jpet.106.109728","volume":"320","author":"L Leventhal","year":"2007","unstructured":"Leventhal L, Smith V, Hornby G, Andree TH, Brandt MR, Rogers KE (2007) Differential and synergistic effects of selective norepinephrine and serotonin reuptake inhibitors in rodent models of pain. J Pharmacol Exp Ther 320(3):1178\u20131185 PubMed PMID: 17142646","journal-title":"J Pharmacol Exp Ther"},{"issue":"23","key":"2302_CR88","doi-asserted-by":"publisher","first-page":"1138","DOI":"10.1016\/j.lfs.2013.04.015","volume":"92","author":"K Suehiro","year":"2013","unstructured":"Suehiro K, Funao T, Fujimoto Y, Yamada T, Mori T, Nishikawa K (2013) Relationship between noradrenaline release in the locus coeruleus and antiallodynic efficacy of analgesics in rats with painful diabetic neuropathy. Life Sci 92(23):1138\u20131144. https:\/\/doi.org\/10.1016\/j.lfs.2013.04.015 PubMed PMID: 23651660","journal-title":"Life Sci"},{"issue":"2","key":"2302_CR89","first-page":"602","volume":"262","author":"SR Tella","year":"1992","unstructured":"Tella SR, Schindler CW, Goldberg SR (1992) Cardiovascular effects of cocaine in conscious rats: relative significance of central sympathetic stimulation and peripheral neuronal monoamine uptake and release mechanisms. J Pharmacol Exp Ther 262(2):602\u2013610 PubMed PMID: 1501115","journal-title":"J Pharmacol Exp Ther"},{"issue":"1","key":"2302_CR90","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1111\/bph.12423","volume":"171","author":"CW Schindler","year":"2014","unstructured":"Schindler CW, Thorndike EB, Blough BE, Tella SR, Goldberg SR, Baumann MH (2014) Effects of 3,4-methylenedioxymethamphetamine (MDMA) and its main metabolites on cardiovascular function in conscious rats. Br J Pharmacol 171(1):83\u201391. https:\/\/doi.org\/10.1111\/bph.12423 PubMed PMID: 24328722; PubMed Central PMCID: PMC3874698","journal-title":"Br J Pharmacol"},{"key":"2302_CR91","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.ejphar.2015.03.079","volume":"758","author":"HA Alsufyani","year":"2015","unstructured":"Alsufyani HA, Docherty JR (2015) Direct and indirect cardiovascular actions of cathinone and MDMA in the anaesthetized rat. Eur J Pharmacol 758:142\u2013146. https:\/\/doi.org\/10.1016\/j.ejphar.2015.03.079 PubMed PMID: 25863258","journal-title":"Eur J Pharmacol"},{"issue":"3","key":"2302_CR92","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1007\/s00213-012-2855-1","volume":"225","author":"KJ Varner","year":"2013","unstructured":"Varner KJ, Daigle K, Weed PF, Lewis PB, Mahne SE, Sankaranarayanan A, Winsauer PJ (2013) Comparison of the behavioral and cardiovascular effects of mephedrone with other drugs of abuse in rats. Psychopharmacology 225(3):675\u2013685. https:\/\/doi.org\/10.1007\/s00213-012-2855-1 PubMed PMID: 22972412; PubMed Central PMCID: PMC3538107","journal-title":"Psychopharmacology"},{"issue":"1","key":"2302_CR93","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.toxlet.2011.10.010","volume":"208","author":"H Meng","year":"2012","unstructured":"Meng H, Cao J, Kang J, Ying X, Ji J, Reynolds W, Rampe D (2012) Mephedrone, a new designer drug of abuse, produces acute hemodynamic effects in the rat. Toxicol Lett 208(1):62\u201368. https:\/\/doi.org\/10.1016\/j.toxlet.2011.10.010 PubMed PMID: 22037396","journal-title":"Toxicol Lett"},{"issue":"24","key":"2302_CR94","doi-asserted-by":"publisher","first-page":"3492","DOI":"10.1111\/bph.13640","volume":"173","author":"CW Schindler","year":"2016","unstructured":"Schindler CW, Thorndike EB, Suzuki M, Rice KC, Baumann MH (2016) Pharmacological mechanisms underlying the cardiovascular effects of the \u201cbath salt\u201d constituent 3,4-methylenedioxypyrovalerone (MDPV). Br J Pharmacol 173(24):3492\u20133501. https:\/\/doi.org\/10.1111\/bph.13640 PubMed PMID: 27714779; PubMed Central PMCID: PMC5120154","journal-title":"Br J Pharmacol"},{"issue":"1-3","key":"2302_CR95","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.ejphar.2012.01.001","volume":"679","author":"JR Docherty","year":"2012","unstructured":"Docherty JR (2012) Yohimbine antagonises \u03b11A- and \u03b11D-adrenoceptor mediated components in addition to the \u03b12A-adrenoceptor component to pressor responses in the pithed rat. Eur J Pharmacol 679(1-3):90\u201394. https:\/\/doi.org\/10.1016\/j.ejphar.2012.01.001 PubMed PMID: 22290390","journal-title":"Eur J Pharmacol"},{"issue":"5","key":"2302_CR96","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1097\/JCP.0b013e3182979d32","volume":"33","author":"CM Hysek","year":"2013","unstructured":"Hysek CM, Fink AE, Simmler LD, Donzelli M, Grouzmann E, Liechti ME (2013) \u03b11-Adrenergic receptors contribute to the acute effects of 3,4-methylenedioxymethamphetamine in humans. J Clin Psychopharmacol 33(5):658\u2013666. https:\/\/doi.org\/10.1097\/JCP.0b013e3182979d32 PubMed PMID: 23857311","journal-title":"J Clin Psychopharmacol"},{"key":"2302_CR97","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.ejphar.2018.10.047","volume":"843","author":"HA Alsufyani","year":"2019","unstructured":"Alsufyani HA, Docherty JR (2019) Methylhexaneamine causes tachycardia and pressor responses indirectly by releasing noradrenaline in the rat. Eur J Pharmacol 843:121\u2013125. https:\/\/doi.org\/10.1016\/j.ejphar.2018.10.047 PubMed PMID: 30395850","journal-title":"Eur J Pharmacol"},{"issue":"1-2","key":"2302_CR98","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.resp.2008.06.016","volume":"164","author":"JC Viemari","year":"2008","unstructured":"Viemari JC (2008) Noradrenergic modulation of the respiratory neural network. Respir Physiol Neurobiol 164(1-2):123\u2013130. https:\/\/doi.org\/10.1016\/j.resp.2008.06.016 PubMed PMID: 18634907","journal-title":"Respir Physiol Neurobiol"},{"issue":"4","key":"2302_CR99","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1152\/jn.01308.2005","volume":"95","author":"JC Viemari","year":"2006","unstructured":"Viemari JC, Ramirez JM (2006) Norepinephrine differentially modulates different types of respiratory pacemaker and nonpacemaker neurons. J Neurophysiol 95(4):2070\u20132082 PubMed PMID: 16394066","journal-title":"J Neurophysiol"},{"issue":"2","key":"2302_CR100","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1152\/jn.01153.2002","volume":"91","author":"JC Viemari","year":"2004","unstructured":"Viemari JC, B\u00e9vengut M, Coulon P, Hilaire G (2004) Nasal trigeminal inputs release the A5 inhibition received by the respiratory rhythm generator of the mouse neonate. J Neurophysiol 91(2):746\u2013758 PubMed PMID: 14561692","journal-title":"J Neurophysiol"},{"issue":"3","key":"2302_CR101","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.1152\/jn.00023.2016","volume":"116","author":"LM Oliveira","year":"2016","unstructured":"Oliveira LM, Moreira TS, Kuo FS, Mulkey DK, Takakura AC (2016) \u03b11- and \u03b12-adrenergic receptors in the retrotrapezoid nucleus differentially regulate breathing in anesthetized adult rats. J Neurophysiol 116(3):1036\u20131048. https:\/\/doi.org\/10.1152\/jn.00023.2016 PubMed PMID: 27306670; PubMed Central PMCID: PMC5009208","journal-title":"J Neurophysiol"},{"issue":"11","key":"2302_CR102","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1164\/rccm.201407-1262OC","volume":"190","author":"PG Burke","year":"2014","unstructured":"Burke PG, Abbott SB, Coates MB, Viar KE, Stornetta RL, Guyenet PG (2014) Optogenetic stimulation of adrenergic C1 neurons causes sleep state-dependent cardiorespiratory stimulation and arousal with sighs in rats. Am J Respir Crit Care Med 190(11):1301\u20131310. https:\/\/doi.org\/10.1164\/rccm.201407-1262OC PubMed PMID: 25325789; PubMed Central PMCID: PMC4315817","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"2302_CR103","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1111\/1556-4029.13509","volume":"63","author":"RW Byard","year":"2018","unstructured":"Byard RW, Donkin J, Vink R (2018) The forensic implications of amphetamine intoxication in cases of inflicted blunt craniocerebral trauma. J Forensic Sci 63(1):151\u2013153. https:\/\/doi.org\/10.1111\/1556-4029.13509","journal-title":"J Forensic Sci"},{"issue":"4","key":"2302_CR104","doi-asserted-by":"publisher","first-page":"383","DOI":"10.7205\/milmed.172.4.383","volume":"172","author":"U Eliyahu","year":"2007","unstructured":"Eliyahu U, Berlin S, Hadad E, Heled Y, Moran DS (2007) Psychostimulants and military operations. Mil Med 172(4):383\u2013387. PMID: 17484308. https:\/\/doi.org\/10.7205\/milmed.172.4.383","journal-title":"Mil Med"},{"key":"2302_CR105","doi-asserted-by":"publisher","first-page":"109941","DOI":"10.1016\/j.forsciint.2019.109941","volume":"304","author":"F Vaiano","year":"2019","unstructured":"Vaiano F, Pascali JP, Bertol E (2019) New psychoactive substances: an actual problem or an overestimated phenomenon? Forensic Sci Int 304:109941. https:\/\/doi.org\/10.1016\/j.forsciint.2019.109941","journal-title":"Forensic Sci Int"},{"issue":"3","key":"2302_CR106","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1080\/15389588.2019.1579320","volume":"20","author":"JP Pascali","year":"2019","unstructured":"Pascali JP, Vaiano F, Palumbo D, Umani Ronchi F, Mari F, Bertol E (2019) Psychotropic substance abuse and fitness to hold a driving license in Italy. Traffic Inj Prev 20(3):244\u2013248. https:\/\/doi.org\/10.1080\/15389588.2019.1579320","journal-title":"Traffic Inj Prev"},{"key":"2302_CR107","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1136\/oemed-2013-101452","volume":"71","author":"E Girotto","year":"2014","unstructured":"Girotto E, Mesas AE, de Andrade SM, Birolim MM (2014) Psychoactive substance use by truck drivers: a systematic review. Occup Environ Med 71:71\u201376","journal-title":"Occup Environ Med"},{"issue":"2","key":"2302_CR108","doi-asserted-by":"publisher","first-page":"E124","DOI":"10.15167\/2421-4248\/jpmh2019.60.2.1245","volume":"60","author":"G Dini","year":"2019","unstructured":"Dini G, Bragazzi NL, Montecucco A, Rahmani A, Durando P (2019) Psychoactive drug consumption among truck-drivers: a systematic review of the literature with meta-analysis and meta-regression. J Prev Med Hyg 60(2):E124\u2013E139. https:\/\/doi.org\/10.15167\/2421-4248\/jpmh2019.60.2.1245 eCollection 2019 Jun","journal-title":"J Prev Med Hyg"},{"issue":"10209","key":"2302_CR109","doi-asserted-by":"publisher","first-page":"1668","DOI":"10.1016\/S0140-6736(19)32231-7","volume":"394","author":"A Peacock","year":"2019","unstructured":"Peacock A, Bruno R, Gisev N, Degenhardt L, Hall W, Sedefov R, White J, Thomas KV, Farrell M, Griffiths P (2019) New psychoactive substances: challenges for drug surveillance, control, and public health responses. Lancet 394(10209):1668\u20131684. https:\/\/doi.org\/10.1016\/S0140-6736(19)32231-7","journal-title":"Lancet"},{"issue":"6","key":"2302_CR110","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1002\/dta.2189","volume":"9","author":"GL Rosso","year":"2017","unstructured":"Rosso GL, Montomoli C, Morini L, Candura SM (2017) Seven years of workplace drug testing in Italy: a systematic review and meta-analysis. Drug Test Anal. 9(6):844\u2013852. https:\/\/doi.org\/10.1002\/dta.2189","journal-title":"Drug Test Anal."},{"issue":"3","key":"2302_CR111","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1002\/dta.2229","volume":"10","author":"M Brcak","year":"2018","unstructured":"Brcak M, Beck O, Bosch T, Carmichael D, Fucci N, George C, Piper M, Salomone A, Schielen W, Steinmeyer S, Taskinen S, Weinmann W (2018) European guidelines for workplace drug testing in oral fluid. Drug Test Anal 10(3):402\u2013415. https:\/\/doi.org\/10.1002\/dta.2229","journal-title":"Drug Test Anal"},{"key":"2302_CR112","doi-asserted-by":"publisher","unstructured":"Salomone A, Palamar JJ, Vincenti M (2020) Should NPS be included in workplace drug testing? Drug Test Anal 12(2):191\u2013194. https:\/\/doi.org\/10.1002\/dta.2749","DOI":"10.1002\/dta.2749"},{"issue":"3","key":"2302_CR113","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1111\/dar.12312","volume":"35","author":"KE Champion","year":"2016","unstructured":"Champion KE, Teesson M, Newton NC (2016) Patterns and correlates f new psychoactive substance use in a sample of Australian high school students. Drug Alcohol Rev 35(3):338\u2013344. https:\/\/doi.org\/10.1111\/dar.12312","journal-title":"Drug Alcohol Rev"},{"issue":"12","key":"2302_CR114","doi-asserted-by":"publisher","first-page":"2077","DOI":"10.1080\/10826084.2018.1455700","volume":"53","author":"LE Kunst","year":"2018","unstructured":"Kunst LE, Gebhardt WA (2018) Prevalence and psychosocial correlates of party-drug use and associated problems among university students in the Netherlands. Subst Use Misuse 53(12):2077\u20132088. https:\/\/doi.org\/10.1080\/10826084.2018.1455700","journal-title":"Subst Use Misuse"}],"container-title":["International Journal of Legal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00414-020-02302-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00414-020-02302-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00414-020-02302-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T12:47:59Z","timestamp":1620046079000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00414-020-02302-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,1]]},"references-count":114,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["2302"],"URL":"https:\/\/doi.org\/10.1007\/s00414-020-02302-3","relation":{},"ISSN":["0937-9827","1437-1596"],"issn-type":[{"value":"0937-9827","type":"print"},{"value":"1437-1596","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,1]]},"assertion":[{"value":"26 February 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 April 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 May 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All applicable international, national, and institutional guidelines for the care and use of animals were followed. All procedures performed in the studies involving animals were in accordance with the ethical standards of the institution or practice at which the studies were conducted.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}