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Subsequent periodical CT scans termed \u201csequential scans\u201d for ten corpses at known time of death were obtained, and a 3D segmentation of the entire LCV was carried out to measure its volume and radiodensity over time from\u2009~\u20095.5- h up to 273-h postmortem. A linear decrease of the LCV volume for all the cases was observed in the investigated time range, together with an overall logarithmic increase of radiodensity. Although a larger sampling should be performed to improve the result reliability, our finding suggests that the postmortem variation of CSF radiodensity can be a potentially useful tool in determining postmortem interval, a finding that is worthy of further investigation.<\/jats:p>","DOI":"10.1007\/s00414-021-02698-6","type":"journal-article","created":{"date-parts":[[2021,9,25]],"date-time":"2021-09-25T08:02:41Z","timestamp":1632556961000},"page":"2615-2623","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Estimation of the time of death by measuring the variation of lateral cerebral ventricle volume and cerebrospinal fluid radiodensity using postmortem computed tomography"],"prefix":"10.1007","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7433-0924","authenticated-orcid":false,"given":"Fabio","family":"De-Giorgio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Ciasca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gennaro","family":"Fecondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Mazzini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"De Spirito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo L.","family":"Pascali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,9,25]]},"reference":[{"key":"2698_CR1","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1016\/j.legalmed.2006.11.011","volume":"9","author":"MJ Thali","year":"2007","unstructured":"Thali MJ, Jackowski C, Oesterhelweg L, Ross SG, Dirnhofer R (2007) VIRTOPSY - the Swiss virtual autopsy approach. 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