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All the procedures were performed in accordance with institutional ethical guidelines and the Declaration of Helsinki Principles. Moreover, this study was conducted using autopsy records from the past, and we could not obtain informed consent from the bereaved family for the use of these records. Therefore, we conducted this study in accordance with the\"Ethical Guidelines for Medical Research Involving Human Subjects (enacted by the Ministry of Health, Labor, and Welfare in Japan), section 12\u20131 (2) (a) (c).\u201d This was a de-identified study using archived tissue obtained from judicial autopsy cases, and the information on the implementation of the study was posted on our website (\n                      \n                      ). The review board of the Research Ethics Committee of Wakayama Medical University waived the need for written informed consent from the relatives of the individuals studied in accordance with the national legislation and the institutional requirements.\u00a0","order":1,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable. Anonymized case files of this retrospective.","order":2,"name":"Ethics","label":"Ethical considerations","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"study were stored locally and data extraction was performed exclusively at the institute.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All applicable international,\u00a0national and\/or institutional guidelines and standards were followed.","order":4,"name":"Ethics","label":"Research involving human participants and\/or animal","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":5,"name":"Ethics","label":"<b>Informed consent<\/b>","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":6,"name":"Ethics","label":"<b>Conflict of interest<\/b>","group":{"name":"EthicsHeading","label":"Declarations"}}]}}