{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T22:12:06Z","timestamp":1778969526698,"version":"3.51.4"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1007\/s00415-005-0610-9","type":"journal-article","created":{"date-parts":[[2005,1,14]],"date-time":"2005-01-14T15:48:08Z","timestamp":1105717688000},"page":"78-83","source":"Crossref","is-referenced-by-count":10,"title":["Fatigue in patients with lupus is not associated with disturbances in cerebral blood flow as detected by SPECT"],"prefix":"10.1007","volume":"252","author":[{"given":"Roald","family":"Omdal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans","family":"Sj\ufffdholm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenche","family":"Koldingsnes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan A.","family":"Sundsfjord","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva A.","family":"Jacobsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunnar","family":"Husby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svein I.","family":"Mellgren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/BF00862972","volume":"239","author":"Tola","year":"1992","unstructured":"Tola MR, Granieri E, Caniatti L, et al. (1992) Systemic lupus erythematosus presenting with neurological disorders. J Neurol 239:61?64","journal-title":"J Neurol"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"283","DOI":"10.3109\/03009748909095031","volume":"18","author":"Omdal","year":"1989","unstructured":"Omdal R, Selseth B, Kl\u00f8w EN, Husby G and Mellgren SI (1989) Clinical neurological, electrophysiological, and cerebral CT scan findings in systemic lupus erythematosus. Scand J Rheumatol 18:283?289","journal-title":"Scand J Rheumatol"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1002\/ana.410230411","volume":"23","author":"Divinsky","year":"1988","unstructured":"Divinsky OD, Petito CK, Alonso DR (1988) Clinical and neuropathological findings in systemic lupus erythematosus. Ann Neurol 23:380?384","journal-title":"Ann Neurol"},{"key":"CR4","first-page":"732","volume":"19","author":"Hanly","year":"1992","unstructured":"Hanly JG, Walsh NMG, Sanalang V (1992) Brain pathology in systemic lupus erythematosus. J Rheumatol 19:732?741","journal-title":"J Rheumatol"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1136\/ard.53.5.304","volume":"53","author":"Denburg","year":"1994","unstructured":"Denburg JA, Behmann SA (1994) Lymphocyte and neuronal antigens in neuropsychiatric lupus. Ann Rheum Dis 53:304?308","journal-title":"Ann Rheum Dis"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1097\/00019052-199612000-00011","volume":"9","author":"Krupp","year":"1996","unstructured":"Krupp LB, Pollina DA (1996) Mechanisms and management of fatigue in progressive neurological disorders. Curr Opin Neurol 9:456?460","journal-title":"Curr Opin Neurol"},{"key":"CR7","first-page":"1450","volume":"17","author":"Krupp","year":"1990","unstructured":"Krupp LB, LaRocca NG, Muir J, Steinberg AD (1990) A study of fatigue in systemic lupus erythematosus. J Rheumatol 17:1450?1452","journal-title":"J Rheumatol"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1191\/096120300678828046","volume":"9","author":"Zonana-Nacach","year":"2000","unstructured":"Zonana-Nacach A, Roseman JM, McGwin G Jr, et al. (2000) Systemic lupus erythematosus in three ethnic groups.VI: Factors associated with fatigue within 5 years of criteria diagnosis. Lupus 9:101?109","journal-title":"Lupus"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1001\/archneur.1989.00520460115022","volume":"46","author":"Krupp","year":"1989","unstructured":"Krupp LB, LaRocca NG, Muir-Nash J, Steinberg AD (1989) The fatigue severity scale. Application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol 46:1121?1123","journal-title":"Arch Neurol"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1093\/rheumatology\/39.11.1249","volume":"39","author":"Tench","year":"2000","unstructured":"Tench CM, McCurdie I, White PD, D?Cruz DP (2000) The prevalence of fatigue in systemic lupus erythematosus. Rheumatology 39:1249?1254","journal-title":"Rheumatology"},{"key":"CR11","first-page":"482","volume":"29","author":"Omdal","year":"2002","unstructured":"Omdal R, Mellgren SI, Koldingsnes W, Jacobsen EA, Husby G (2002) Fatigue in patients with systemic lupus erythematosus: lack of associations to serum cytokines, antiphospholipid antibodies, or other disease characteristics. J Rheumatol 29:482?486","journal-title":"J Rheumatol"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1038\/bjc.1993.319","volume":"68","author":"Smets","year":"1993","unstructured":"Smets E, Garssen B, Schuster-Uitterhoeve A, de Haes J (1993) Fatigue in cancer patients. Br J Cancer 68:220?224","journal-title":"Br J Cancer"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1002\/1097-0142(20010915)92:6+<1678::AID-CNCR1496>3.0.CO;2-R","volume":"92","author":"Gutstein","year":"2001","unstructured":"Gutstein HB (2001) The biologic basis of fatigue. Cancer 92:1678?1683","journal-title":"Cancer"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1212\/WNL.48.6.1566","volume":"48","author":"Roelcke","year":"1997","unstructured":"Roelcke U, Kappos L, Lechner-Scott J, et al. (1997) Reduced glucose metabolism in the frontal cortex and basal ganglia of multiple sclerosis patients with fatigue. Neurology 48:1566?1571","journal-title":"Neurology"},{"key":"CR15","first-page":"1407","volume":"23","author":"Wolfe","year":"1996","unstructured":"Wolfe F, Hawley DJ, Wilson K (1996) The prevalence and meaning of fatigue in rheumatic disease. J Rheumatol 23:1407?1417","journal-title":"J Rheumatol"},{"key":"CR16","doi-asserted-by":"crossref","first-page":"141","DOI":"10.3109\/s101650070021","volume":"10","author":"Koike","year":"2000","unstructured":"Koike T, Kazuma K, Kawamura S (2000) The relationship between fatigue, coping behaviour, and inflammation in patients with rheumatoid arthritis. Mod Rheumatol 10:141?149","journal-title":"Mod Rheumatol"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1002\/1531-8257(199903)14:2<237::AID-MDS1006>3.0.CO;2-X","volume":"14","author":"Karlsen","year":"1999","unstructured":"Karlsen K, Larsen JP, Tandberg E, J\u00f8rgensen K (1999) Fatigue in patients with Parkinson?s disease. Mov Disord 14:237?241","journal-title":"Mov Disord"},{"key":"CR18","first-page":"892","volume":"25","author":"Wang","year":"1998","unstructured":"Wang B, Gladman DD, Urowitz MB (1998) Fatigue in lupus is not correlated with disease activity. J Rheumatol 25:892?895","journal-title":"J Rheumatol"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1136\/ard.58.6.379","volume":"58","author":"Bruce","year":"1999","unstructured":"Bruce IN, Mak VC, Hallett DC, Gladman DD, Urowitz MB (1999) Factors associated with fatigue in patients with systemic lupus erythematosus. Ann Rheum 58:379?381","journal-title":"Ann Rheum"},{"key":"CR20","first-page":"283","volume":"30","author":"Omdal","year":"2003","unstructured":"Omdal R, Waterloo K, Koldingsnes W, Husby G, Mellgren SI (2003) Fatigue in patients with systemic lupus erythematosus: the psychosocial aspects. J Rheumatol 30:283?287","journal-title":"J Rheumatol"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1212\/WNL.44.10.1970","volume":"44","author":"Masdeu","year":"1994","unstructured":"Masdeu J, Brass L, Holman L, Kushner M (1994) Brain single photon emission computed tomography. Neurology 44:1970?1977","journal-title":"Neurology"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1002\/art.1780360910","volume":"36","author":"Ruppert","year":"1993","unstructured":"Ruppert A, Marienhagen A, Pirner K, et al. (1993) Single-photon emission computed tomography analysis of cerebral blood flow in the evaluation of central nervous system involvement in patients with systemic lupus erythematosus. Arthritis Rheum 36:1253?1262","journal-title":"Arthritis Rheum"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1136\/jnnp.58.3.307","volume":"58","author":"Kodama","year":"1995","unstructured":"Kodama K, Okada S, Hino T, et al. (1995) Single photon emission computed tomography in systemic lupus erythematosus with psychiatric symptoms. J Neurol Neurosurg Psychiatry 58:307?311","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s005990050015","volume":"28","author":"Postiglione","year":"1998","unstructured":"Postiglione A, De Chiara S, Soricelli A, et al. (1998) Alterations of cerebral blood flow and antiphospholipid antibodies in patients with systemic lupus erythematosus. Int J Clin Lab Res 28:34?38","journal-title":"Int J Clin Lab Res"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"953","DOI":"10.7326\/0003-4819-121-12-199412150-00009","volume":"121","author":"Fukuda","year":"1994","unstructured":"Fukuda K, Straus SE, Hickie I, et al. (1994) The chronic fatigue syndrome: a comprehensive approach to its definition and study. Ann Intern Med 121:953?959","journal-title":"Ann Intern Med"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1097\/00006231-199213100-00011","volume":"13","author":"Ichise","year":"1992","unstructured":"Ichise M, Salit IE, Abbey SE, et al. (1992) Assessment of regional cerebral perfusion by 99mTc-HMPAO SPECT in chronic fatigue syndrome. Nucl Med Commun 13:767?772","journal-title":"Nucl Med Commun"},{"key":"CR27","first-page":"767","volume":"88","author":"Costa","year":"1995","unstructured":"Costa DC, Tannock C, Brostoff J (1995) Brainstem perfusion is impaired in chronic fatigue syndrome. QJM 88:767?773","journal-title":"QJM"},{"key":"CR28","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1148\/radiology.219.3.r01jn18766","volume":"219","author":"Lewis","year":"2001","unstructured":"Lewis DH, Mayberg HS, Fischer ME, et al. (2001) Monozygotic twins discordant for chronic fatigue syndrome: regional cerebral blood flow SPECT. Radiology 219:766?773","journal-title":"Radiology"},{"key":"CR29","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1159\/000119307","volume":"34","author":"Fischler","year":"1996","unstructured":"Fischler B, D?Haenen H, Cluydts J, et al. (1996) Comparison of 99mTc HMPAO SPECT scan between chronic fatigue syndrome,major depression and healthy controls: an explanatory study of clinical correlates of regional cerebral blood flow. Neuropsychobiology 34:175?183","journal-title":"Neuropsychobiology"},{"key":"CR30","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1002\/art.1780251101","volume":"25","author":"Tan","year":"1982","unstructured":"Tan EM, Cohen AS, Fries JF, et al. (1982) The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 25:1271?1272","journal-title":"Arthritis Rheum"},{"key":"CR31","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1002\/art.1780350606","volume":"35","author":"Bombardieri","year":"1992","unstructured":"Bombardieri C, Gladman DD, Urowitz MB, Caron D, Chang CH, and the Committee on Prognosis Studies in SLE (1992) Derivation of the SLEDAI: a disease activity index for lupus patients. Arthritis Rheum 35:630?640","journal-title":"Arthritis Rheum"},{"key":"CR32","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s004150170138","volume":"248","author":"Waterloo","year":"2001","unstructured":"Waterloo K, Omdal R, Sj\u00f6holm H, et al. (2001) Neuropsychological dysfunction in systemic lupus erythematosus is not associated with changes in cerebral blood flow. J Neurol 248:595?602","journal-title":"J Neurol"},{"key":"CR33","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/jcbfm.1991.95","volume":"11","author":"Waldemar","year":"1991","unstructured":"Waldemar G, Hasselbalch SG, Andersen AR, Delecluse F, Petersen P, Johnsen A, Paulson OB (1991) 99mTcd, l-HMPAO and SPECT of the brain in normal aging. J Cereb Blood Flow Metab 11:508?521","journal-title":"J Cereb Blood Flow Metab"},{"key":"CR34","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0960-5428(96)00014-9","volume":"6","author":"Krupp","year":"1996","unstructured":"Krupp LB, Pollina D (1996) Neuroimmune and neuropsychiatric aspects of chronic fatigue syndrome. Adv Neuroimmunol 6:155?167","journal-title":"Adv Neuroimmunol"},{"key":"CR35","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0278-5846(02)00309-3","volume":"27","author":"Vangu","year":"2003","unstructured":"Vangu MD, Esser JD, Boyd IH, Berk M (2003) Effects of electroconvulsive therapy on regional cerebral blood flow measured by 99m-technetium HMPAO SPECT. Prog Neuropsychopharmacol Biol Psychiatry 27:9?15","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"CR36","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/1529-0131(199901)42:1<61::AID-ANR8>3.0.CO;2-9","volume":"42","author":"Kao","year":"1999","unstructured":"Kao CH, Ho Y-J, Lan J-L, Changlai SP, Liao K-K, Chiang P-U (1999) Discrepancy between regional cerebral blood flow and glucose metabolism of the brain in systemic lupus erythematosus patients with normal brain magnetic resonance imaging findings. Arthritis Rheum 42:61?68","journal-title":"Arthritis Rheum"},{"key":"CR37","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1007\/BF00808421","volume":"22","author":"Gr\u00fcnwald","year":"1995","unstructured":"Gr\u00fcnwald F, Schomburg A, Badali A, Ruhlmann J, Pavics L, Biersack HJ (1995) 18FDG PET and acetazolamide-enhanced 99mTc-HMPAU SPET in systemic lupus erythematosus. Eur J Nucl Med 22:1073?1077","journal-title":"Eur J Nucl Med"},{"key":"CR38","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1007\/s004150050071","volume":"244","author":"Sailor","year":"1997","unstructured":"Sailor M, Burchert W, Ehrenheim C, et al. (1997) Positron emission tomography and magnetic resonance imaging for cerebral involvement in patients with systemic lupus erythematosus. J Neurol 244:186?193","journal-title":"J Neurol"}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-005-0610-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00415-005-0610-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-005-0610-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T15:03:56Z","timestamp":1559055836000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00415-005-0610-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["610"],"URL":"https:\/\/doi.org\/10.1007\/s00415-005-0610-9","relation":{},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,1]]}}}