{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T03:22:17Z","timestamp":1791861737844,"version":"4.3.4"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1007\/s00415-009-5196-1","type":"journal-article","created":{"date-parts":[[2009,6,26]],"date-time":"2009-06-26T14:12:25Z","timestamp":1246025545000},"page":"1961-1965","source":"Crossref","is-referenced-by-count":87,"title":["Delayed onset of the diurnal melatonin rise in patients with Huntington\u2019s disease"],"prefix":"10.1007","volume":"256","author":[{"given":"N. Ahmad","family":"Aziz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanno","family":"Pijl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marijke","family":"Fr\u00f6lich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janny P.","family":"Schr\u00f6der-van der Elst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Bent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferdinand","family":"Roelfsema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymund A. C.","family":"Roos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2009,6,27]]},"reference":[{"issue":"4","key":"5196_CR1","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1001\/archneur.65.4.482","volume":"65","author":"I Arnulf","year":"2008","unstructured":"Arnulf I, Nielsen J, Lohmann E, Schieffer J, Wild E, Jennum P et al (2008) Rapid eye movement sleep disturbances in Huntington disease. Arch Neurol 65(4):482\u2013488. doi: 10.1001\/archneur.65.4.482","journal-title":"Arch Neurol"},{"issue":"4","key":"5196_CR2","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1111\/j.1750-3639.2008.00135.x","volume":"18","author":"A Aziz","year":"2008","unstructured":"Aziz A, Fronczek R, Maat-Schieman M, Unmehopa U, Roelandse F, Overeem S et al (2008) Hypocretin and melanin-concentrating hormone in patients with Huntington disease. Brain Pathol 18(4):474\u2013483","journal-title":"Brain Pathol"},{"issue":"4","key":"5196_CR3","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1210\/jc.2008-2543","volume":"94","author":"NA Aziz","year":"2009","unstructured":"Aziz NA, Pijl H, Frolich M, van der Graaf AW, Roelfsema F, Roos RA (2009) Increased hypothalamic\u2013pituitary\u2013adrenal axis activity in Huntington\u2019s disease. J Clin Endocrinol Metab 94(4):1223\u20131228","journal-title":"J Clin Endocrinol Metab"},{"key":"5196_CR4","volume-title":"Huntington\u2019s disease","author":"G Bates","year":"2002","unstructured":"Bates G, Harper PS, Jones L (2002) Huntington\u2019s disease, 3rd edn. Oxford University Press, New York","edition":"3"},{"issue":"8","key":"5196_CR5","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1212\/01.wnl.0000324283.57261.37","volume":"71","author":"EE Benarroch","year":"2008","unstructured":"Benarroch EE (2008) Suprachiasmatic nucleus and melatonin: reciprocal interactions and clinical correlations. Neurology 71(8):594\u2013598. doi: 10.1212\/01.wnl.0000324283.57261.37","journal-title":"Neurology"},{"issue":"3","key":"5196_CR6","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0028-3908(99)00128-8","volume":"39","author":"J Cabrera","year":"2000","unstructured":"Cabrera J, Reiter RJ, Tan DX, Qi W, Sainz RM, Mayo JC et al (2000) Melatonin reduces oxidative neurotoxicity due to quinolinic acid: in vitro and in vivo findings. Neuropharmacology 39(3):507\u2013514. doi: 10.1016\/S0028-3908(99)00128-8","journal-title":"Neuropharmacology"},{"issue":"4","key":"5196_CR7","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1111\/j.1471-4159.2006.03807.x","volume":"97","author":"J Christofides","year":"2006","unstructured":"Christofides J, Bridel M, Egerton M, Mackay GM, Forrest CM, Stoy N et al (2006) Blood 5-hydroxytryptamine, 5-hydroxyindoleacetic acid and melatonin levels in patients with either Huntington\u2019s disease or chronic brain injury. J Neurochem 97(4):1078\u20131088. doi: 10.1111\/j.1471-4159.2006.03807.x","journal-title":"J Neurochem"},{"issue":"3","key":"5196_CR8","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/BF00314313","volume":"235","author":"W Emser","year":"1988","unstructured":"Emser W, Brenner M, Stober T, Schimrigk K (1988) Changes in nocturnal sleep in Huntington\u2019s and Parkinson\u2019s disease. J Neurol 235(3):177\u2013179. doi: 10.1007\/BF00314313","journal-title":"J Neurol"},{"issue":"2","key":"5196_CR9","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1002\/mds.870110204","volume":"11","author":"Huntington Study Group","year":"1996","unstructured":"Huntington Study Group (1996) Unified Huntington\u2019s disease rating scale: reliability and consistency. Huntington study group. Mov Disord 11(2):136\u2013142. doi: 10.1002\/mds.870110204","journal-title":"Mov Disord"},{"issue":"6","key":"5196_CR10","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1007\/s00415-005-0709-z","volume":"252","author":"CB Hurelbrink","year":"2005","unstructured":"Hurelbrink CB, Lewis SJ, Barker RA (2005) The use of the Actiwatch-Neurologica system to objectively assess the involuntary movements and sleep-wake activity in patients with mild\u2013moderate Huntington\u2019s disease. J Neurol 252(6):642\u2013647. doi: 10.1007\/s00415-005-0709-z","journal-title":"J Neurol"},{"issue":"3","key":"5196_CR11","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1111\/j.1365-2265.2005.02341.x","volume":"63","author":"R Leproult","year":"2005","unstructured":"Leproult R, Van Onderbergen A, L\u2019hermite-Baleriaux M, Van Cauter E, Copinschi G (2005) Phase-shifts of 24-h rhythms of hormonal release and body temperature following early evening administration of the melatonin agonist agomelatine in healthy older men. Clin Endocrinol (Oxf) 63(3):298\u2013304. doi: 10.1111\/j.1365-2265.2005.02341.x","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"3","key":"5196_CR12","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1152\/physrev.1989.69.3.671","volume":"69","author":"JH Meijer","year":"1989","unstructured":"Meijer JH, Rietveld WJ (1989) Neurophysiology of the suprachiasmatic circadian pacemaker in rodents. Physiol Rev 69(3):671\u2013707","journal-title":"Physiol Rev"},{"issue":"11","key":"5196_CR13","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1093\/sleep\/30.11.1445","volume":"30","author":"TI Morgenthaler","year":"2007","unstructured":"Morgenthaler TI, Lee-Chiong T, Alessi C, Friedman L, Aurora RN, Boehlecke B et al (2007) Practice parameters for the clinical evaluation and treatment of circadian rhythm sleep disorders. An American academy of sleep medicine report. Sleep 30(11):1445\u20131459","journal-title":"Sleep"},{"issue":"1","key":"5196_CR14","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1523\/JNEUROSCI.3842-04.2005","volume":"25","author":"AJ Morton","year":"2005","unstructured":"Morton AJ, Wood NI, Hastings MH, Hurelbrink C, Barker RA, Maywood ES (2005) Disintegration of the sleep\u2013wake cycle and circadian timing in Huntington\u2019s disease. J Neurosci 25(1):157\u2013163. doi: 10.1523\/JNEUROSCI.3842-04.2005","journal-title":"J Neurosci"},{"issue":"29","key":"5196_CR15","doi-asserted-by":"crossref","first-page":"7869","DOI":"10.1523\/JNEUROSCI.0649-07.2007","volume":"27","author":"PN Pallier","year":"2007","unstructured":"Pallier PN, Maywood ES, Zheng Z, Chesham JE, Inyushkin AN, Dyball R et al (2007) Pharmacological imposition of sleep slows cognitive decline and reverses dysregulation of circadian gene expression in a transgenic mouse model of Huntington\u2019s disease. J Neurosci 27(29):7869\u20137878. doi: 10.1523\/JNEUROSCI.0649-07.2007","journal-title":"J Neurosci"},{"issue":"13","key":"5196_CR16","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1111\/j.1742-4658.2006.05322.x","volume":"273","author":"SR Pandi-Perumal","year":"2006","unstructured":"Pandi-Perumal SR, Srinivasan V, Maestroni GJ, Cardinali DP, Poeggeler B, Hardeland R (2006) Melatonin: nature\u2019s most versatile biological signal? FEBS J 273(13):2813\u20132838. doi: 10.1111\/j.1742-4658.2006.05322.x","journal-title":"FEBS J"},{"issue":"3","key":"5196_CR17","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.pneurobio.2008.04.001","volume":"85","author":"SR Pandi-Perumal","year":"2008","unstructured":"Pandi-Perumal SR, Trakht I, Srinivasan V, Spence DW, Maestroni GJ, Zisapel N et al (2008) Physiological effects of melatonin: role of melatonin receptors and signal transduction pathways. Prog Neurobiol 85(3):335\u2013353. doi: 10.1016\/j.pneurobio.2008.04.001","journal-title":"Prog Neurobiol"},{"key":"5196_CR18","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1744-9081-2-15","volume":"2","author":"V Srinivasan","year":"2006","unstructured":"Srinivasan V, Pandi-Perumal SR, Cardinali DP, Poeggeler B, Hardeland R (2006) Melatonin in Alzheimer\u2019s disease and other neurodegenerative disorders. Behav Brain Funct 2:15. doi: 10.1186\/1744-9081-2-15","journal-title":"Behav Brain Funct"},{"issue":"3","key":"5196_CR19","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1111\/j.1471-4159.2005.03070.x","volume":"93","author":"N Stoy","year":"2005","unstructured":"Stoy N, Mackay GM, Forrest CM, Christofides J, Egerton M, Stone TW et al (2005) Tryptophan metabolism and oxidative stress in patients with Huntington\u2019s disease. J Neurochem 93(3):611\u2013623. doi: 10.1111\/j.1471-4159.2005.03070.x","journal-title":"J Neurochem"},{"key":"5196_CR20","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1192\/bjp.171.4.393c","volume":"171","author":"N Taylor","year":"1997","unstructured":"Taylor N, Bramble D (1997) Sleep disturbance and Huntingdon\u2019s disease. Br J Psychiatry 171:393. doi: 10.1192\/bjp.171.4.393c","journal-title":"Br J Psychiatry"},{"issue":"4","key":"5196_CR21","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1111\/j.1600-079X.2004.00163.x","volume":"37","author":"I Tunez","year":"2004","unstructured":"Tunez I, Montilla P, Del Carmen MM, Feijoo M, Salcedo M (2004) Protective effect of melatonin on 3-nitropropionic acid-induced oxidative stress in synaptosomes in an animal model of Huntington\u2019s disease. J Pineal Res 37(4):252\u2013256. doi: 10.1111\/j.1600-079X.2004.00163.x","journal-title":"J Pineal Res"},{"key":"5196_CR22","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.parkreldis.2008.10.002","volume":"15","author":"A Videnovic","year":"2009","unstructured":"Videnovic A, Leurgans S, Fan W, Jaglin J, Shannon KM (2009) Daytime somnolence and nocturnal sleep disturbances in Huntington disease. Parkinsonism Relat Disord 15:471\u2013474. doi: 10.1016\/j.parkreldis.2008.10.002","journal-title":"Parkinsonism Relat Disord"},{"issue":"38","key":"5196_CR23","doi-asserted-by":"crossref","first-page":"9473","DOI":"10.1523\/JNEUROSCI.1867-08.2008","volume":"28","author":"X Wang","year":"2008","unstructured":"Wang X, Zhu S, Pei Z, Drozda M, Stavrovskaya IG, Del Signore SJ et al (2008) Inhibitors of cytochrome c release with therapeutic potential for Huntington\u2019s disease. J Neurosci 28(38):9473\u20139485. doi: 10.1523\/JNEUROSCI.1867-08.2008","journal-title":"J Neurosci"},{"issue":"4","key":"5196_CR24","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/BF00314781","volume":"238","author":"M Wiegand","year":"1991","unstructured":"Wiegand M, Moller AA, Lauer CJ, Stolz S, Schreiber W, Dose M et al (1991) Nocturnal sleep in Huntington\u2019s disease. J Neurol 238(4):203\u2013208. doi: 10.1007\/BF00314781","journal-title":"J Neurol"},{"issue":"4","key":"5196_CR25","doi-asserted-by":"crossref","first-page":"311","DOI":"10.2165\/00023210-200115040-00005","volume":"15","author":"N Zisapel","year":"2001","unstructured":"Zisapel N (2001) Circadian rhythm sleep disorders: pathophysiology and potential approaches to management. CNS Drugs 15(4):311\u2013328. doi: 10.2165\/00023210-200115040-00005","journal-title":"CNS Drugs"}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-009-5196-1.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T22:03:17Z","timestamp":1710453797000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00415-009-5196-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6,27]]},"references-count":25,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["5196"],"URL":"https:\/\/doi.org\/10.1007\/s00415-009-5196-1","relation":{},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,6,27]]}}}