{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:08:50Z","timestamp":1790716130504,"version":"4.1.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"S2","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1007\/s00415-010-5720-3","type":"journal-article","created":{"date-parts":[[2010,11,15]],"date-time":"2010-11-15T15:09:33Z","timestamp":1289833773000},"page":"298-304","source":"Crossref","is-referenced-by-count":30,"title":["Dopaminergic therapy and subthalamic stimulation in Parkinson\u2019s disease: a review of 5-year reports"],"prefix":"10.1007","volume":"257","author":[{"given":"Luigi M.","family":"Romito","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Albanese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,11,16]]},"reference":[{"key":"5720_CR1","first-page":"365","volume":"91","author":"Y Agid","year":"2003","unstructured":"Agid Y, Arnulf I, Bejjani P, Bloch F, Bonnet AM, Damier P, Dubois B, Francois C, Houeto JL, Iacono D, Karachi C, Mesnage V, Messouak O, Vidailhet M, Welter ML, Yelnik J (2003) Parkinson\u2019s disease is a neuropsychiatric disorder. Adv Neurol 91:365\u2013370","journal-title":"Adv Neurol"},{"key":"5720_CR2","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1176\/ajp.127.10.1422","volume":"127","author":"NP Bechtereva","year":"1971","unstructured":"Bechtereva NP, Hughes HK (1971) Implanted electrodes: experimentation on humans? Am J Psychiatry 127:1422\u20131423","journal-title":"Am J Psychiatry"},{"key":"5720_CR3","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1002\/1531-8249(200005)47:5<655::AID-ANA16>3.0.CO;2-#","volume":"47","author":"BP Bejjani","year":"2000","unstructured":"Bejjani BP, Arnulf I, Demeret S, Damier P, Bonnet AM, Houeto JL, Agid Y (2000) Levodopa-induced dyskinesias in Parkinson\u2019s disease: is sensitization reversible? Ann Neurol 47:655\u2013658","journal-title":"Ann Neurol"},{"key":"5720_CR4","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S1474-4422(08)70291-6","volume":"8","author":"AL Benabid","year":"2009","unstructured":"Benabid AL, Chabardes S, Mitrofanis J, Pollak P (2009) Deep brain stimulation of the subthalamic nucleus for the treatment of Parkinson\u2019s disease. Lancet Neurol 8:67\u201381","journal-title":"Lancet Neurol"},{"key":"5720_CR5","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1159\/000098600","volume":"62","author":"AL Benabid","year":"1994","unstructured":"Benabid AL, Pollak P, Gross C, Hoffmann D, Benazzouz A, Gao DM, Laurent A, Gentil M, Perret J (1994) Acute and long-term effects of subthalamic nucleus stimulation in Parkinson\u2019s disease. Stereotact Funct Neurosurg 62:76\u201384","journal-title":"Stereotact Funct Neurosurg"},{"key":"5720_CR6","first-page":"344","volume":"50","author":"AL Benabid","year":"1987","unstructured":"Benabid AL, Pollak P, Louveau A, Henry S, de RJ (1987) Combined (thalamotomy and stimulation) stereotactic surgery of the VIM thalamic nucleus for bilateral Parkinson disease. Appl Neurophysiol 50:344\u2013346","journal-title":"Appl Neurophysiol"},{"key":"5720_CR7","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1212\/WNL.37.9.1539","volume":"37","author":"AM Bonnet","year":"1987","unstructured":"Bonnet AM, Loria Y, Saint-Hilaire MH, Lhermitte F, Agid Y (1987) Does long-term aggravation of Parkinson\u2019s disease result from nondopaminergic lesions? Neurology 37:1539\u20131542","journal-title":"Neurology"},{"key":"5720_CR8","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/S1474-4422(09)70068-7","volume":"8","author":"KR Chaudhuri","year":"2009","unstructured":"Chaudhuri KR, Schapira AH (2009) Non-motor symptoms of Parkinson\u2019s disease: dopaminergic pathophysiology and treatment. Lancet Neurol 8:464\u2013474","journal-title":"Lancet Neurol"},{"key":"5720_CR9","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1136\/jnnp.2005.086660","volume":"78","author":"MF Contarino","year":"2007","unstructured":"Contarino MF, Daniele A, Sibilia AH, Romito LM, Bentivoglio AR, Gainotti G, Albanese A (2007) Cognitive outcome 5\u00a0years after bilateral chronic stimulation of subthalamic nucleus in patients with Parkinson\u2019s disease. J Neurol Neurosurg Psychiatry 78:248\u2013252","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"5720_CR10","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1002\/1531-8257(199907)14:4<572::AID-MDS1005>3.0.CO;2-C","volume":"14","author":"GL Defer","year":"1999","unstructured":"Defer GL, Widner H, Marie RM, Remy P, Levivier M (1999) Core assessment program for surgical interventional therapies in Parkinson\u2019s disease (CAPSIT-PD). Mov Disord 14:572\u2013584","journal-title":"Mov Disord"},{"key":"5720_CR11","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1136\/jnnp.2002.009803","volume":"75","author":"A Funkiewiez","year":"2004","unstructured":"Funkiewiez A, Ardouin C, Caputo E, Krack P, Fraix V, Klinger H, Chabardes S, Foote K, Benabid AL, Pollak P (2004) Long term effects of bilateral subthalamic nucleus stimulation on cognitive function, mood, and behaviour in Parkinson\u2019s disease. J Neurol Neurosurg Psychiatry 75:834\u2013839","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"5720_CR12","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s00415-009-0076-2","volume":"256","author":"H Gervais-Bernard","year":"2009","unstructured":"Gervais-Bernard H, Xie-Brustolin J, Mertens P, Polo G, Klinger H, Adamec D, Broussolle E, Thobois S (2009) Bilateral subthalamic nucleus stimulation in advanced Parkinson\u2019s disease: five year follow-up. J Neurol 256:225\u2013233","journal-title":"J Neurol"},{"key":"5720_CR13","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1002\/mds.21387","volume":"22","author":"J Herzog","year":"2007","unstructured":"Herzog J, Pinsker M, Wasner M, Steigerwald F, Wailke S, Deuschl G, Volkmann J (2007) Stimulation of subthalamic fibre tracts reduces dyskinesias in STN-DBS. Mov Disord 22:679\u2013684","journal-title":"Mov Disord"},{"key":"5720_CR14","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","volume":"55","author":"AJ Hughes","year":"1992","unstructured":"Hughes AJ, Daniel SE, Kilford L, Lees AJ (1992) Accuracy of clinical diagnosis of idiopathic Parkinson\u2019s disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 55:181\u2013184","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"5720_CR15","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1159\/000094957","volume":"84","author":"Y Katayama","year":"2006","unstructured":"Katayama Y, Oshima H, Kano T, Kobayashi K, Fukaya C, Yamamoto T (2006) Direct effect of subthalamic nucleus stimulation on levodopa-induced peak-dose dyskinesia in patients with Parkinson\u2019s disease. Stereotact Funct Neurosurg 84:176\u2013179","journal-title":"Stereotact Funct Neurosurg"},{"key":"5720_CR16","doi-asserted-by":"crossref","first-page":"489","DOI":"10.3171\/jns.2003.99.3.0489","volume":"99","author":"G Kleiner-Fisman","year":"2003","unstructured":"Kleiner-Fisman G, Fisman DN, Sime E, Saint-Cyr JA, Lozano AM, Lang AE (2003) Long-term follow up of bilateral deep brain stimulation of the subthalamic nucleus in patients with advanced Parkinson disease. J Neurosurg 99:489\u2013495","journal-title":"J Neurosurg"},{"key":"5720_CR17","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1056\/NEJMoa035275","volume":"349","author":"P Krack","year":"2003","unstructured":"Krack P, Batir A, Van BN, Chabardes S, Fraix V, Ardouin C, Koudsie A, Limousin PD, Benazzouz A, Lebas JF, Benabid AL, Pollak P (2003) Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson\u2019s disease. N Engl J Med 349:1925\u20131934","journal-title":"N Engl J Med"},{"key":"5720_CR18","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1212\/WNL.0b013e3181c34b34","volume":"73","author":"JF Le","year":"2009","unstructured":"Le JF, Drapier D, Bourguignon A, Peron J, Mesbah H, Drapier S, Sauleau P, Haegelen C, Travers D, Garin E, Malbert CH, Millet B, Verin M (2009) Subthalamic nucleus stimulation in Parkinson disease induces apathy: a PET study. Neurology 73:1746\u20131751","journal-title":"Neurology"},{"key":"5720_CR19","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1016\/S0140-6736(09)60492-X","volume":"373","author":"AJ Lees","year":"2009","unstructured":"Lees AJ, Hardy J, Revesz T (2009) Parkinson\u2019s disease. Lancet 373:2055\u20132066","journal-title":"Lancet"},{"key":"5720_CR20","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.nurt.2008.01.006","volume":"5","author":"P Limousin","year":"2008","unstructured":"Limousin P, Martinez-Torres I (2008) Deep brain stimulation for Parkinson\u2019s disease. Neurotherapeutics 5:309\u2013319","journal-title":"Neurotherapeutics"},{"key":"5720_CR21","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1016\/S1474-4422(09)70291-1","volume":"8","author":"W Maetzler","year":"2009","unstructured":"Maetzler W, Liepelt I, Berg D (2009) Progression of Parkinson\u2019s disease in the clinical phase: potential markers. Lancet Neurol 8:1158\u20131171","journal-title":"Lancet Neurol"},{"key":"5720_CR22","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1523\/JNEUROSCI.2949-06.2007","volume":"27","author":"A Oueslati","year":"2007","unstructured":"Oueslati A, Sgambato-Faure V, Melon C, Kachidian P, Gubellini P, Amri M, Kerkerian-Le GL, Salin P (2007) High-frequency stimulation of the subthalamic nucleus potentiates l-DOPA-induced neurochemical changes in the striatum in a rat model of Parkinson\u2019s disease. J Neurosci 27:2377\u20132386","journal-title":"J Neurosci"},{"key":"5720_CR23","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3171\/jns.2003.99.1.0071","volume":"99","author":"R Pahwa","year":"2003","unstructured":"Pahwa R, Wilkinson SB, Overman J, Lyons KE (2003) Bilateral subthalamic stimulation in patients with Parkinson disease: long-term follow up. J Neurosurg 99:71\u201377","journal-title":"J Neurosurg"},{"key":"5720_CR24","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1002\/mds.21482","volume":"22","author":"P Piboolnurak","year":"2007","unstructured":"Piboolnurak P, Lang AE, Lozano AM, Miyasaki JM, Saint-Cyr JA, Poon YY, Hutchison WD, Dostrovsky JO, Moro E (2007) Levodopa response in long-term bilateral subthalamic stimulation for Parkinson\u2019s disease. Mov Disord 22:990\u2013997","journal-title":"Mov Disord"},{"key":"5720_CR25","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1093\/brain\/awh571","volume":"128","author":"MC Rodriguez-Oroz","year":"2005","unstructured":"Rodriguez-Oroz MC, Obeso JA, Lang AE, Houeto JL, Pollak P, Rehncrona S, Kulisevsky J, Albanese A, Volkmann J, Hariz MI, Quinn NP, Speelman JD, Guridi J, Zamarbide I, Gironell A, Molet J, Pascual-Sedano B, Pidoux B, Bonnet AM, Agid Y, Xie J, Benabid AL, Lozano AM, Saint-Cyr J, Romito L, Contarino MF, Scerrati M, Fraix V, Van BN (2005) Bilateral deep brain stimulation in Parkinson\u2019s disease: a multicentre study with 4\u00a0years follow-up. Brain 128:2240\u20132249","journal-title":"Brain"},{"key":"5720_CR26","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1002\/mds.22390","volume":"24","author":"LM Romito","year":"2008","unstructured":"Romito LM, Contarino MF, Vanacore N, Bentivoglio AR, Scerrati M, Albanese A (2008) Replacement of dopaminergic medication with subthalamic nucleus stimulation in Parkinson\u2019s disease: long-term observation. Mov Disord 24:555\u2013561","journal-title":"Mov Disord"},{"key":"5720_CR27","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1002\/mds.22390","volume":"24","author":"LM Romito","year":"2009","unstructured":"Romito LM, Contarino MF, Vanacore N, Bentivoglio AR, Scerrati M, Albanese A (2009) Replacement of dopaminergic medication with subthalamic nucleus stimulation in Parkinson\u2019s disease: long-term observation. Mov Disord 24:557\u2013563","journal-title":"Mov Disord"},{"key":"5720_CR28","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1212\/WNL.58.10.1546","volume":"58","author":"LM Romito","year":"2002","unstructured":"Romito LM, Scerrati M, Contarino MF, Bentivoglio AR, Tonali P, Albanese A (2002) Long-term follow up of subthalamic nucleus stimulation in Parkinson\u2019s disease. Neurology 58:1546\u20131550","journal-title":"Neurology"},{"key":"5720_CR29","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1136\/jnnp.2005.063206","volume":"76","author":"WM Schupbach","year":"2005","unstructured":"Schupbach WM, Chastan N, Welter ML, Houeto JL, Mesnage V, Bonnet AM, Czernecki V, Maltete D, Hartmann A, Mallet L, Pidoux B, Dormont D, Navarro S, Cornu P, Mallet A, Agid Y (2005) Stimulation of the subthalamic nucleus in Parkinson\u2019s disease: a 5\u00a0year follow up. J Neurol Neurosurg Psychiatry 76:1640\u20131644","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"5720_CR30","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1227\/00006123-199412000-00016","volume":"35","author":"J Siegfried","year":"1994","unstructured":"Siegfried J, Lippitz B (1994) Bilateral chronic electrostimulation of ventroposterolateral pallidum: a new therapeutic approach for alleviating all parkinsonian symptoms. Neurosurgery 35:1126\u20131129","journal-title":"Neurosurgery"},{"key":"5720_CR31","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1007\/s00415-009-5195-2","volume":"256","author":"C Simonin","year":"2009","unstructured":"Simonin C, Tir M, Devos D, Kreisler A, Dujardin K, Salleron J, Delval A, Blond S, Defebvre L, Destee A, Krystkowiak P (2009) Reduced levodopa-induced complications after 5\u00a0years of subthalamic stimulation in Parkinson\u2019s disease: a second honeymoon. J Neurol 256:1736\u20131741","journal-title":"J Neurol"},{"issue":"Suppl 3","key":"5720_CR32","doi-asserted-by":"crossref","first-page":"S599","DOI":"10.1002\/mds.22052","volume":"23","author":"F Stocchi","year":"2008","unstructured":"Stocchi F, Tagliati M, Olanow CW (2008) Treatment of levodopa-induced motor complications. Mov Disord 23(Suppl 3):S599\u2013S612","journal-title":"Mov Disord"},{"key":"5720_CR33","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.parkreldis.2004.10.011","volume":"11","author":"V Visser-Vandewalle","year":"2005","unstructured":"Visser-Vandewalle V, van der LC, Temel Y, Celik H, Ackermans L, Spincemaille G, Caemaert J (2005) Long-term effects of bilateral subthalamic nucleus stimulation in advanced Parkinson disease: a four year follow-up study. Parkinsonism Relat Disord 11:157\u2013165","journal-title":"Parkinsonism Relat Disord"},{"key":"5720_CR34","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1016\/S1474-4422(09)70287-X","volume":"8","author":"V Voon","year":"2009","unstructured":"Voon V, Fernagut PO, Wickens J, Baunez C, Rodriguez M, Pavon N, Juncos JL, Obeso JA, Bezard E (2009) Chronic dopaminergic stimulation in Parkinson\u2019s disease: from dyskinesias to impulse control disorders. Lancet Neurol 8:1140\u20131149","journal-title":"Lancet Neurol"},{"key":"5720_CR35","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1093\/brain\/awm137","volume":"130","author":"BA Wallace","year":"2007","unstructured":"Wallace BA, Ashkan K, Heise CE, Foote KD, Torres N, Mitrofanis J, Benabid AL (2007) Survival of midbrain dopaminergic cells after lesion or deep brain stimulation of the subthalamic nucleus in MPTP-treated monkeys. Brain 130:2129\u20132145","journal-title":"Brain"},{"key":"5720_CR36","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1136\/jnnp.2004.061481","volume":"76","author":"PC Warnke","year":"2005","unstructured":"Warnke PC (2005) STN stimulation and neuroprotection in Parkinson\u2019s disease\u2013when beautiful theories meet ugly facts. J Neurol Neurosurg Psychiatry 76:1186\u20131187","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"5720_CR37","doi-asserted-by":"crossref","unstructured":"Wider C, Pollo C, Bloch J, Burkhard PR, Vingerhoets FJ (2007) Long-term outcome of 50 consecutive Parkinson\u2019s disease patients treated with subthalamic deep brain stimulation. Parkinsonism Relat Disord 14:114\u2013119","DOI":"10.1016\/j.parkreldis.2007.06.012"},{"key":"5720_CR38","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.parkreldis.2007.12.009","volume":"14","author":"M Zibetti","year":"2008","unstructured":"Zibetti M, Pesare M, Cinquepalmi A, Rosso M, Bergamasco B, Ducati A, Lanotte M, Lopiano L (2008) Antiparkinsonian therapy modifications in PD patients after STN DBS: a retrospective observational analysis. Parkinsonism Relat Disord 14:608\u2013612","journal-title":"Parkinsonism Relat Disord"}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-010-5720-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00415-010-5720-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-010-5720-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T15:13:01Z","timestamp":1559056381000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00415-010-5720-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":38,"journal-issue":{"issue":"S2","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["5720"],"URL":"https:\/\/doi.org\/10.1007\/s00415-010-5720-3","relation":{},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,11]]}}}