{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T22:55:58Z","timestamp":1791845758954,"version":"4.3.4"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1007\/s00415-010-5876-x","type":"journal-article","created":{"date-parts":[[2010,12,24]],"date-time":"2010-12-24T14:10:33Z","timestamp":1293199833000},"page":"1034-1041","source":"Crossref","is-referenced-by-count":75,"title":["Summary of cerebrospinal fluid routine parameters in neurodegenerative diseases"],"prefix":"10.1007","volume":"258","author":[{"given":"Sarah","family":"Jesse","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Brettschneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sigurd D.","family":"S\u00fcssmuth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard G.","family":"Landwehrmeyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine A. F.","family":"Arnim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert C.","family":"Ludolph","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayrettin","family":"Tumani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Otto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,12,25]]},"reference":[{"key":"5876_CR1","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1001\/archneur.56.6.673","volume":"56","author":"N Andreasen","year":"1999","unstructured":"Andreasen N, Hesse C, Davidsson P, Minthon L, Wallin A, Winblad B, Vanderstichele H, Vanmechelen E, Blennow K (1999) Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease. Arch Neurol 56:673\u2013680","journal-title":"Arch Neurol"},{"issue":"2","key":"5876_CR2","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/j.1600-0404.1991.tb04656.x","volume":"83","author":"S Apostolski","year":"1991","unstructured":"Apostolski S et al (1991) Serum and CSF immunological findings in ALS. Acta Neurol Scand 83(2):96\u201398","journal-title":"Acta Neurol Scand"},{"key":"5876_CR3","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1007\/s00415-005-0817-9","volume":"252","author":"J Brettschneider","year":"2005","unstructured":"Brettschneider J, Claus A, Kassubek J, Tumani H (2005) Isolated blood\u2013cerebrospinal fluid barrier dysfunction: prevalence and associated diseases. J Neurol 252:1067\u20131073","journal-title":"J Neurol"},{"key":"5876_CR4","doi-asserted-by":"crossref","first-page":"e7638","DOI":"10.1371\/journal.pone.0007638","volume":"4","author":"J Brettschneider","year":"2009","unstructured":"Brettschneider J, Tumani H, Kiechle U, Muche R, Richards G, Lehmensiek V, Ludolph AC, Otto M (2009) IgG antibodies against measles, rubella, and varicella zoster virus predict conversion to multiple sclerosis in clinically isolated syndrome. PLoS One 4:e7638","journal-title":"PLoS One"},{"key":"5876_CR5","unstructured":"Deutsche Gesellschaft f\u00fcr Psychiatrie PuN, Deutsche Gesellschaft f\u00fcr Neurologie (2009) S3-Leitlinie Demenzen. 038\/013"},{"key":"5876_CR6","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1093\/jnen\/61.11.935","volume":"61","author":"DW Dickson","year":"2002","unstructured":"Dickson DW, Bergeron C, Chin SS, Duyckaerts C, Horoupian D, Ikeda K, Jellinger K, Lantos PL, Lippa CF, Mirra SS, Tabaton M, Vonsattel JP, Wakabayashi K, Litvan I (2002) Office of rare diseases neuropathologic criteria for corticobasal degeneration. J Neuropathol Exp Neurol 61:935\u2013946","journal-title":"J Neuropathol Exp Neurol"},{"key":"5876_CR7","doi-asserted-by":"crossref","first-page":"2314","DOI":"10.1002\/mds.21844","volume":"22","author":"B Dubois","year":"2007","unstructured":"Dubois B, Burn D, Goetz C, Aarsland D, Brown RG, Broe GA, Dickson D, Duyckaerts C, Cummings J, Gauthier S, Korczyn A, Lees A, Levy R, Litvan I, Mizuno Y, McKeith IG, Olanow CW, Poewe W, Sampaio C, Tolosa E, Emre M (2007) Diagnostic procedures for Parkinson\u2019s disease dementia: recommendations from the movement disorder society task force. Mov Disord 22:2314\u20132324","journal-title":"Mov Disord"},{"key":"5876_CR8","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/BF02279767","volume":"240","author":"L Frolich","year":"1991","unstructured":"Frolich L, Kornhuber J, Ihl R, Fritze J, Maurer K, Riederer P (1991) Integrity of the blood\u2013CSF barrier in dementia of Alzheimer type: CSF\/serum ratios of albumin and IgG. Eur Arch Psychiatry Clin Neurosci 240:363\u2013366","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"5876_CR9","first-page":"2081","volume":"45","author":"A Fuchs","year":"1904","unstructured":"Fuchs A, Rosenthal R (1904) Physikalisch-chemische, zytologische und anderweitige Untersuchungen der Cerebrospinalfl\u00fcssigkeit. Wien Med Presse 45:2081\u20132087","journal-title":"Wien Med Presse"},{"key":"5876_CR10","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/BF02309628","volume":"8","author":"S Gilman","year":"1998","unstructured":"Gilman S, Low P, Quinn N, Albanese A, Ben-Shlomo Y, Fowler C, Kaufmann H, Klockgether T, Lang A, Lantos P, Litvan I, Mathias C, Oliver E, Robertson D, Schatz I, Wenning G (1998) Consensus statement on the diagnosis of multiple system atrophy. American Autonomic Society and American Academy of Neurology. Clin Auton Res 8:359\u2013362","journal-title":"Clin Auton Res"},{"key":"5876_CR11","first-page":"348","volume":"6","author":"Hampel H","year":"1995","unstructured":"H Hampel, M\u00fcller-Spahn F, Berger C, Haberl A, Ackenheil M, Hock C (1995) Evidence of blood\u2013cerebrospinal fluid-barrier impairment in a subgroup of patients with dementia of the Alzheimer type and major depression: a possible indicator for immunoactivation. Dementia 6:348\u2013354","journal-title":"Dementia"},{"key":"5876_CR12","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1097\/00002093-199903000-00002","volume":"13","author":"H Hampel","year":"1999","unstructured":"Hampel H, Kotter HU, Padberg F, Korschenhausen DA, Moller HJ (1999) Oligoclonal bands and blood\u2013cerebrospinal-fluid barrier dysfunction in a subset of patients with Alzheimer disease: comparison with vascular dementia, major depression, and multiple sclerosis. Alzheimer Dis Assoc Disord 13:9\u201319","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"5876_CR13","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1111\/j.1468-1331.2009.02646.x","volume":"16","author":"HF Harbo","year":"2009","unstructured":"Harbo HF, Finsterer J, Baets J, Van Broeckhoven C, Di Donato S, Fontaine B, De Jonghe P, Lossos A, Lynch T, Mariotti C, Schols L, Spinazzola A, Szolnoki Z, Tabrizi SJ, Tallaksen C, Zeviani M, Burgunder JM, Gasser T (2009) EFNS guidelines on the molecular diagnosis of neurogenetic disorders: general issues, Huntington\u2019s disease, Parkinson\u2019s disease and dystonias. Eur J Neurol 16:777\u2013785","journal-title":"Eur J Neurol"},{"key":"5876_CR14","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1007\/s00415-004-0296-4","volume":"251","author":"JC Janssen","year":"2004","unstructured":"Janssen JC, Godbolt AK, Ioannidis P, Thompson EJ, Rossor MN (2004) The prevalence of oligoclonal bands in the CSF of patients with primary neurodegenerative dementia. J Neurol 251:184\u2013188","journal-title":"J Neurol"},{"key":"5876_CR15","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1177\/000456329002700504","volume":"27","author":"G Keir","year":"1990","unstructured":"Keir G, Luxton RW, Thompson L (1990) Isoelectric focusing of cerebrospinal fluid immunoglobulin G: an annotated update. Ann Clin Biochem 27:436\u2013443","journal-title":"Ann Clin Biochem"},{"key":"5876_CR16","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1007\/s00115-005-1992-8","volume":"76","author":"T Klockgether","year":"2005","unstructured":"Klockgether T (2005) Ataxias Diagnostic procedure and treatment. Nervenarzt 76:1275\u20131283 quiz 1284-1275","journal-title":"Nervenarzt"},{"key":"5876_CR17","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/BF00313720","volume":"231","author":"A Leonardi","year":"1984","unstructured":"Leonardi A, Abbruzzese G, Arata L, Cocito L, Vische M (1984) Cerebrospinal fluid (CSF) findings in amyotrophic lateral sclerosis. J Neurol 231:75\u201378","journal-title":"J Neurol"},{"key":"5876_CR18","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1385\/JMN:23:1-2:115","volume":"23","author":"P Lewczuk","year":"2004","unstructured":"Lewczuk P, Esselmann H, Bibl M, Beck G, Maler JM, Otto M, Kornhuber J, Wiltfang J (2004) Tau protein phosphorylated at threonine 181 in CSF as a neurochemical biomarker in Alzheimer\u2019s disease: original data and review of the literature. J Mol Neurosci 23:115\u2013122","journal-title":"J Mol Neurosci"},{"key":"5876_CR19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1212\/WNL.47.1.1","volume":"47","author":"I Litvan","year":"1996","unstructured":"Litvan I, Agid Y, Calne D, Campbell G, Dubois B, Duvoisin RC, Goetz CG, Golbe LI, Grafman J, Growdon JH, Hallett M, Jankovic J, Quinn NP, Tolosa E, Zee DS (1996) Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele\u2013Richardson\u2013Olszewski syndrome): report of the NINDS-SPSP international workshop. Neurology 47:1\u20139","journal-title":"Neurology"},{"key":"5876_CR20","doi-asserted-by":"crossref","first-page":"417","DOI":"10.3233\/JAD-2006-9S347","volume":"9","author":"IG McKeith","year":"2006","unstructured":"McKeith IG (2006) Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. J Alzheimers Dis 9:417\u2013423","journal-title":"J Alzheimers Dis"},{"key":"5876_CR21","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1212\/WNL.34.7.939","volume":"34","author":"G McKhann","year":"1984","unstructured":"McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer\u2019s disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer\u2019s Disease. Neurology 34:939\u2013944","journal-title":"Neurology"},{"key":"5876_CR22","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1212\/WNL.51.6.1546","volume":"51","author":"D Neary","year":"1998","unstructured":"Neary D, Snowden JS, Gustafson L, Passant U, Stuss D, Black S, Freedman M, Kertesz A, Robert PH, Albert M, Boone K, Miller BL, Cummings J, Benson DF (1998) Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 51:1546\u20131554","journal-title":"Neurology"},{"key":"5876_CR23","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1373\/clinchem.2009.136051","volume":"56","author":"M Otto","year":"2010","unstructured":"Otto M (2010) Dementia diagnostics 2.0\u2013transfer from research studies into routine clinical practice. Clin Chem 56:152\u2013153","journal-title":"Clin Chem"},{"key":"5876_CR24","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-510X(94)90298-4","volume":"122","author":"H Reiber","year":"1994","unstructured":"Reiber H (1994) Flow rate of cerebrospinal fluid (CSF)- a concept common to normal blood\u2013CSF barrier function and to dysfunction in neurological diseases. J Neurol Sci 122:189\u2013203","journal-title":"J Neurol Sci"},{"key":"5876_CR25","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1093\/clinchem\/41.2.256","volume":"41","author":"H Reiber","year":"1995","unstructured":"Reiber H (1995) External quality assessment in clinical neurochemistry: survey of analysis for cerebrospinal fluid (CSF) proteins based on CSF\/serum quotients. Clin Chem 41:256\u2013263","journal-title":"Clin Chem"},{"key":"5876_CR26","first-page":"79","volume":"21","author":"H Reiber","year":"2003","unstructured":"Reiber H (2003) Proteins in cerebrospinal fluid and blood: barriers, CSF flow rate and source-related dynamics. Restor Neurol Neurosci 21:79\u201396","journal-title":"Restor Neurol Neurosci"},{"key":"5876_CR27","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0022-510X(00)00501-3","volume":"184","author":"H Reiber","year":"2001","unstructured":"Reiber H, Peter JB (2001) Cerebrospinal fluid analysis\u2014disease-related data patterns and evaluation programs. J Neurol Sci 184:101\u2013122","journal-title":"J Neurol Sci"},{"key":"5876_CR28","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1177\/135245859800400304","volume":"4","author":"H Reiber","year":"1998","unstructured":"Reiber H, Ungefehr S, Jacobi C (1998) The intrathecal, polyspecific and oligoclonal immune response in multiple sclerosis. Mult Scler 4:111\u2013117","journal-title":"Mult Scler"},{"key":"5876_CR29","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1515\/CCLM.2001.051","volume":"39","author":"H Reiber","year":"2001","unstructured":"Reiber H, Otto M, Trendelenburg C, Wormek A (2001) Reporting cerebrospinal fluid data: knowledge base and interpretation software. Clin Chem Lab Med 39:324\u2013332","journal-title":"Clin Chem Lab Med"},{"key":"5876_CR30","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1212\/WNL.50.4.966","volume":"50","author":"I Skoog","year":"1998","unstructured":"Skoog I, Wallin A, Fredman P, Hesse C, Aevarsson O, Karlsson I, Gottfries CG, Blennow K (1998) A population study on blood-brain barrier function in 85-year-olds: relation to Alzheimer\u2019s disease and vascular dementia. Neurology 50:966\u2013971","journal-title":"Neurology"},{"key":"5876_CR31","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.2174\/092986708785133031","volume":"15","author":"SD S\u00fcssmuth","year":"2008","unstructured":"S\u00fcssmuth SD (2008) Biochemical markers in CSF of ALS patients. Curr Med Chem 15:1788\u20131801","journal-title":"Curr Med Chem"},{"key":"5876_CR32","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1111\/j.1468-1331.2005.01351.x","volume":"12","author":"The EFNS Task Force on Diagnosis, Management of Amyotrophic Lateral Sclerosis","year":"2005","unstructured":"The EFNS Task Force on Diagnosis, Management of Amyotrophic Lateral Sclerosis (2005) Guidelines for diagnosing and clinical care of patients and relatives. Eur J Neurol 12:921\u2013938","journal-title":"Eur J Neurol"},{"key":"5876_CR33","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1586\/14737159.8.4.479","volume":"8","author":"H Tumani","year":"2008","unstructured":"Tumani H, Teunissen C, Sussmuth S, Otto M, Ludolph AC, Brettschneider J (2008) Cerebrospinal fluid biomarkers of neurodegeneration in chronic neurological diseases. Expert Rev Mol Diagn 8:479\u2013494","journal-title":"Expert Rev Mol Diagn"},{"key":"5876_CR34","doi-asserted-by":"crossref","first-page":"867","DOI":"10.3171\/jns.1985.63.6.0867","volume":"63","author":"ML Upton","year":"1985","unstructured":"Upton ML, Weller RO (1985) The morphology of cerebrospinal fluid drainage pathways in human arachnoid granulations. J Neurosurg 63:867\u2013875","journal-title":"J Neurosurg"},{"key":"5876_CR35","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1111\/j.1471-4159.1993.tb09823.x","volume":"61","author":"M Vandermeeren","year":"1993","unstructured":"Vandermeeren M, Mercken M, Vanmechelen E, Six J, van de Voorde A, Martin JJ, Cras P (1993) Detection of tau proteins in normal and Alzheimer\u2019s disease cerebrospinal fluid with a sensitive sandwich enzyme-linked immunosorbent assay. J Neurochem 61:1828\u20131834","journal-title":"J Neurochem"},{"key":"5876_CR36","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1111\/j.1468-1331.2006.01605.x","volume":"14","author":"G Waldemar","year":"2007","unstructured":"Waldemar G, Dubois B, Emre M, Georges J, McKeith IG, Rossor M, Scheltens P, Tariska P, Winblad B (2007) Recommendations for the diagnosis and management of Alzheimer\u2019s disease and other disorders associated with dementia: EFNS guideline. Eur J Neurol 14:e1\u201326","journal-title":"Eur J Neurol"},{"key":"5876_CR37","doi-asserted-by":"crossref","unstructured":"Zimmermann R, Beck G, Knispel S, Maler JM, Weih M, Wiltfang J, Kornhuber J, Lewczuk P (2010) Intrathecal IgG synthesis in patients with alterations in the neurochemical dementia diagnostics. J Alzheimers Dis 19:1199\u20131203","DOI":"10.3233\/JAD-2010-1313"}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.springerlink.com\/index\/pdf\/10.1007\/s00415-010-5876-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,15]],"date-time":"2020-06-15T00:22:09Z","timestamp":1592180529000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00415-010-5876-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12,25]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["5876"],"URL":"https:\/\/doi.org\/10.1007\/s00415-010-5876-x","relation":{},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,12,25]]}}}