{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T11:29:56Z","timestamp":1784719796095,"version":"3.55.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2013,2,12]],"date-time":"2013-02-12T00:00:00Z","timestamp":1360627200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1007\/s00415-013-6856-8","type":"journal-article","created":{"date-parts":[[2013,2,11]],"date-time":"2013-02-11T07:06:01Z","timestamp":1360566361000},"page":"1743-1747","source":"Crossref","is-referenced-by-count":33,"title":["Fasciculation anxiety syndrome in clinicians"],"prefix":"10.1007","volume":"260","author":[{"given":"Neil G.","family":"Simon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew C.","family":"Kiernan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,2,12]]},"reference":[{"key":"6856_CR1","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1002\/ana.410340419","volume":"34","author":"MD Blexrud","year":"1993","unstructured":"Blexrud MD, Windebank AJ, Daube JR (1993) Long-term follow-up of 121 patients with benign fasciculations. Ann Neurol 34:622\u2013625","journal-title":"Ann Neurol"},{"key":"6856_CR2","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.clinph.2007.09.143","volume":"119","author":"M Carvalho de","year":"2008","unstructured":"de Carvalho M, Dengler R, Eisen A, England JD, Kaji R, Kimura J, Mills K, Mitsumoto H, Nodera H, Shefner J, Swash M (2008) Electrodiagnostic criteria for diagnosis of ALS. Clin Neurophysiol 119:497\u2013503","journal-title":"Clin Neurophysiol"},{"key":"6856_CR3","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1212\/01.WNL.0000134609.56166.15","volume":"63","author":"M Carvalho de","year":"2004","unstructured":"de Carvalho M, Swash M (2004) Cramps, muscle pain, and fasciculations: not always benign? Neurology 63:721\u2013723","journal-title":"Neurology"},{"key":"6856_CR4","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/S0278-5846(00)00130-5","volume":"24","author":"L Dratcu","year":"2000","unstructured":"Dratcu L (2000) Panic, hyperventilation and perpetuation of anxiety. Prog Neuropsychopharmacol Biol Psychiatry 24:1069\u20131089","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"6856_CR5","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1097\/00002060-200107000-00002","volume":"80","author":"D Dumitru","year":"2001","unstructured":"Dumitru D, Diaz CA, King JC (2001) Prevalence of denervation in paraspinal and foot intrinsic musculature. Am J Phys Med Rehabil 80:482\u2013490","journal-title":"Am J Phys Med Rehabil"},{"key":"6856_CR6","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1093\/brain\/awf178","volume":"125","author":"IK Hart","year":"2002","unstructured":"Hart IK, Maddison P, Newsom-Davis J, Vincent A, Mills KR (2002) Phenotypic variants of autoimmune peripheral nerve hyperexcitability. Brain 125:1887\u20131895","journal-title":"Brain"},{"key":"6856_CR7","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1002\/ana.410410215","volume":"41","author":"IK Hart","year":"1997","unstructured":"Hart IK, Waters C, Vincent A, Newland C, Beeson D, Pongs O, Morris C, Newsom-Davis J (1997) Autoantibodies detected to expressed K+ channels are implicated in neuromyotonia. Ann Neurol 41:238\u2013246","journal-title":"Ann Neurol"},{"key":"6856_CR8","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1001\/archpsyc.61.9.913","volume":"61","author":"R Hoehn-Saric","year":"2004","unstructured":"Hoehn-Saric R, McLeod DR, Funderburk F, Kowalski P (2004) Somatic symptoms and physiologic responses in generalized anxiety disorder and panic disorder: an ambulatory monitor study. Arch Gen Psychiatry 61:913\u2013921","journal-title":"Arch Gen Psychiatry"},{"key":"6856_CR9","first-page":"693","volume":"40","author":"W Huynh","year":"2011","unstructured":"Huynh W, Kiernan MC (2011) Nerve conduction studies. Aust Fam Physician 40:693\u2013697","journal-title":"Aust Fam Physician"},{"key":"6856_CR10","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1002\/ana.23577","volume":"72","author":"SR Irani","year":"2012","unstructured":"Irani SR, Pettingill P, Kleopa KA, Schiza N, Waters P, Mazia C, Zuliani L, Watanabe O, Lang B, Buckley C, Vincent A (2012) Morvan syndrome: clinical and serological observations in 29 cases. Ann Neurol 72:241\u2013255","journal-title":"Ann Neurol"},{"key":"6856_CR11","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1007\/BF02191150","volume":"241","author":"PH Jansen","year":"1991","unstructured":"Jansen PH, van Dijck JA, Verbeek AL, Durian FW, Joosten EM (1991) Estimation of the frequency of the muscular pain-fasciculation syndrome and the muscular cramp-fasciculation syndrome in the adult population. Eur Arch Psychiatry Clin Neurosci 241:102\u2013104","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"6856_CR12","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.70.1.56","volume":"70","author":"MC Kiernan","year":"2001","unstructured":"Kiernan MC, Hart IK, Bostock H (2001) Excitability properties of motor axons in patients with spontaneous motor unit activity. J Neurol Neurosurg Psychiatry 70:56\u201364","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"6856_CR13","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/S0140-6736(10)61156-7","volume":"377","author":"MC Kiernan","year":"2011","unstructured":"Kiernan MC, Vucic S, Cheah BC, Turner MR, Eisen A, Hardiman O, Burrell JR, Zoing MC (2011) Amyotrophic lateral sclerosis. Lancet 377:942\u2013955","journal-title":"Lancet"},{"key":"6856_CR14","volume-title":"Electrodiagnosis in diseases of nerve and muscle: principles and practice","author":"J Kimura","year":"2001","unstructured":"Kimura J (2001) Electrodiagnosis in diseases of nerve and muscle: principles and practice. Oxford University Press, New York"},{"key":"6856_CR15","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1002\/mus.880171102","volume":"17","author":"RB Layzer","year":"1994","unstructured":"Layzer RB (1994) The origin of muscle fasciculations and cramps. Muscle Nerve 17:1243\u20131249","journal-title":"Muscle Nerve"},{"key":"6856_CR16","volume-title":"Aid to the examination of the peripheral nervous system","author":"Medical Research Council","year":"1976","unstructured":"Medical Research Council (1976) Aid to the examination of the peripheral nervous system. Her Majesty\u2019s Stationary Office, London"},{"key":"6856_CR17","doi-asserted-by":"crossref","first-page":"3458","DOI":"10.1093\/brain\/awq290","volume":"133","author":"KR Mills","year":"2010","unstructured":"Mills KR (2010) Characteristics of fasciculations in amyotrophic lateral sclerosis and the benign fasciculation syndrome. Brain 133:3458\u20133469","journal-title":"Brain"},{"key":"6856_CR18","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1002\/(SICI)1097-4598(199804)21:4<533::AID-MUS14>3.0.CO;2-Y","volume":"21","author":"DD Mitsikostas","year":"1998","unstructured":"Mitsikostas DD, Karandreas N, Coutsopetras P, Piperos P, Lygidakis C, Papageorgiou C (1998) Fasciculation potentials in healthy people. Muscle Nerve 21:533\u2013535","journal-title":"Muscle Nerve"},{"issue":"Pt 2","key":"6856_CR19","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1093\/brain\/120.2.317","volume":"120","author":"I Mogyoros","year":"1997","unstructured":"Mogyoros I, Kiernan MC, Burke D, Bostock H (1997) Excitability changes in human sensory and motor axons during hyperventilation and ischaemia. Brain 120(Pt 2):317\u2013325","journal-title":"Brain"},{"issue":"Pt 2","key":"6856_CR20","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1093\/brain\/116.2.453","volume":"116","author":"J Newsom-Davis","year":"1993","unstructured":"Newsom-Davis J, Mills KR (1993) Immunological associations of acquired neuromyotonia (Isaacs\u2019 syndrome). Report of five cases and literature review. Brain 116(Pt 2):453\u2013469","journal-title":"Brain"},{"key":"6856_CR21","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1001\/archneur.1963.00460100051005","volume":"9","author":"DM Reed","year":"1963","unstructured":"Reed DM, Kurland LT (1963) Muscle fasciculations in a healthy population. Arch Neurol 9:363\u2013367","journal-title":"Arch Neurol"},{"key":"6856_CR22","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/0013-4694(87)90006-X","volume":"67","author":"G Roth","year":"1987","unstructured":"Roth G, Magistris MR (1987) Neuropathies with prolonged conduction block, single and grouped fasciculations, localized limb myokymia. Electroencephalogr Clin Neurophysiol 67:428\u2013438","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"6856_CR23","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1212\/WNL.0b013e3182061b1e","volume":"76","author":"I Rubio-Agusti","year":"2011","unstructured":"Rubio-Agusti I, Perez-Miralles F, Sevilla T, Muelas N, Chumillas MJ, Mayordomo F, Azorin I, Carmona E, Moscardo F, Palau J, Jacobson L, Vincent A, Vilchez JJ, Bataller L (2011) Peripheral nerve hyperexcitability: a clinical and immunologic study of 38 patients. Neurology 76:172\u2013178","journal-title":"Neurology"},{"key":"6856_CR24","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1136\/bmj.2.4725.209","volume":"2","author":"RS Schwab","year":"1951","unstructured":"Schwab RS, Stafford-Clark D, Prichard JS (1951) The clinical significance of fasciculations in voluntary muscle. Br Med J 2:209\u2013212","journal-title":"Br Med J"},{"key":"6856_CR25","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/s00415-010-5791-1","volume":"258","author":"V Singh","year":"2011","unstructured":"Singh V, Gibson J, McLean B, Boggild M, Silver N, White R (2011) Fasciculations and cramps: how benign? Report of four cases progressing to ALS. J Neurol 258:573\u2013578","journal-title":"J Neurol"},{"key":"6856_CR26","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1212\/WNL.41.7.1021","volume":"41","author":"AJ Tahmoush","year":"1991","unstructured":"Tahmoush AJ, Alonso RJ, Tahmoush GP, Heiman-Patterson TD (1991) Cramp-fasciculation syndrome: a treatable hyperexcitable peripheral nerve disorder. Neurology 41:1021\u20131024","journal-title":"Neurology"},{"key":"6856_CR27","doi-asserted-by":"crossref","first-page":"565","DOI":"10.3109\/17482960903420140","volume":"11","author":"MR Turner","year":"2010","unstructured":"Turner MR, Chen Z (2010) The internet for self-diagnosis and prognostication in ALS. Amyotroph Lateral Scler 11:565\u2013567","journal-title":"Amyotroph Lateral Scler"},{"key":"6856_CR28","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1002\/mus.10266","volume":"26","author":"S Vernino","year":"2002","unstructured":"Vernino S, Lennon VA (2002) Ion channel and striational antibodies define a continuum of autoimmune neuromuscular hyperexcitability. Muscle Nerve 26:702\u2013707","journal-title":"Muscle Nerve"},{"key":"6856_CR29","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1383\/psyt.3.6.80.38211","volume":"3","author":"H Warwick","year":"2004","unstructured":"Warwick H (2004) Treatment of health anxiety. Psychiatry 3:80\u201383","journal-title":"Psychiatry"},{"key":"6856_CR30","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S1474-4422(05)70042-9","volume":"4","author":"JM Winhammar","year":"2005","unstructured":"Winhammar JM, Rowe DB, Henderson RD, Kiernan MC (2005) Assessment of disease progression in motor neuron disease. Lancet Neurol 4:229\u2013238","journal-title":"Lancet Neurol"}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-013-6856-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00415-013-6856-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-013-6856-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T19:23:12Z","timestamp":1559071392000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00415-013-6856-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,12]]},"references-count":30,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["6856"],"URL":"https:\/\/doi.org\/10.1007\/s00415-013-6856-8","relation":{},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,12]]}}}