{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T07:13:34Z","timestamp":1793258014682,"version":"4.5.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T00:00:00Z","timestamp":1465171200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100004362","name":"Schweizerische Herzstiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004362","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1007\/s00415-016-8180-6","type":"journal-article","created":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T06:32:57Z","timestamp":1465194777000},"page":"1633-1640","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":116,"title":["Clinical prediction of large vessel occlusion in anterior circulation stroke: mission impossible?"],"prefix":"10.1007","volume":"263","author":[{"given":"Mirjam R.","family":"Heldner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kety","family":"Hsieh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Broeg-Morvay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasquale","family":"Mordasini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"B\u00fchlmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"Arnold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heinrich P.","family":"Mattle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Gralla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urs","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,6,6]]},"reference":[{"key":"8180_CR1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa1411587","volume":"372","author":"OA Berkhemer","year":"2015","unstructured":"Berkhemer OA, Fransen PS, Beumer D et al (2015) A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 372:11\u201320","journal-title":"N Engl J Med"},{"key":"8180_CR2","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1056\/NEJMoa1414792","volume":"372","author":"BC Campbell","year":"2015","unstructured":"Campbell BC, Mitchell PJ, Kleinig TJ, EXTEND-IA Investigators et al (2015) Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 372:1009\u20131018","journal-title":"N Engl J Med"},{"key":"8180_CR3","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1056\/NEJMoa1414905","volume":"372","author":"M Goyal","year":"2015","unstructured":"Goyal M, Demchuk AM, Menon BK, ESCAPE Trial Investigators et al (2015) Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 372:1019\u20131030","journal-title":"N Engl J Med"},{"key":"8180_CR4","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1056\/NEJMoa1415061","volume":"372","author":"JL Saver","year":"2015","unstructured":"Saver JL, Goyal M, Bonafe A, SWIFT PRIME Investigators et al (2015) Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 372:2285\u20132295","journal-title":"N Engl J Med"},{"key":"8180_CR5","doi-asserted-by":"crossref","first-page":"2296","DOI":"10.1056\/NEJMoa1503780","volume":"372","author":"TG Jovin","year":"2015","unstructured":"Jovin TG, Chamorro A, Cobo E, REVASCAT Trial Investigators et al (2015) Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med 372:2296\u20132306","journal-title":"N Engl J Med"},{"key":"8180_CR6","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1161\/01.STR.20.7.864","volume":"20","author":"T Brott","year":"1989","unstructured":"Brott T, Adams HP Jr, Olinger CP et al (1989) Measurements of acute cerebral infarction: a clinical examination scale. Stroke 20:864\u2013870","journal-title":"Stroke"},{"key":"8180_CR7","doi-asserted-by":"crossref","first-page":"2988","DOI":"10.1161\/STROKEAHA.109.555664","volume":"40","author":"MB Maas","year":"2009","unstructured":"Maas MB, Furie KL, Lev MH et al (2009) National Institutes of Health Stroke Scale score is poorly predictive of proximal occlusion in acute cerebral ischemia. Stroke 40:2988\u20132993","journal-title":"Stroke"},{"key":"8180_CR8","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1212\/WNL.0b013e318203e977","volume":"76","author":"VV Olavarr\u00eda","year":"2011","unstructured":"Olavarr\u00eda VV, Delgado I, Hoppe A et al (2011) Validity of the NIHSS in predicting arterial occlusion in cerebral infarction is time-dependent. Neurology. 76:62\u201368","journal-title":"Neurology."},{"key":"8180_CR9","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1161\/01.STR.0000182099.04994.fc","volume":"36","author":"U Fischer","year":"2005","unstructured":"Fischer U, Arnold M, Nedeltchev K et al (2005) NIHSS score and arteriographic findings in acute ischaemic stroke. Stroke 36:2121\u20132125","journal-title":"Stroke"},{"key":"8180_CR10","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1161\/STROKEAHA.111.000604","volume":"44","author":"MR Heldner","year":"2013","unstructured":"Heldner MR, Zubler C, Mattle HP et al (2013) NIHSS score and vessel occlusion in 2152 patients with acute ischemic stroke. Stroke 44:1153\u20131157","journal-title":"Stroke"},{"key":"8180_CR11","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1111\/ijs.12451","volume":"10","author":"C Cooray","year":"2015","unstructured":"Cooray C, Fekete K, Mikulik R, Lees KR, Wahlgren N, Ahmed N (2015) Threshold for NIH stroke scale in predicting vessel occlusion and functional outcome after stroke thrombolysis. Int J Stroke. 10:822\u2013829","journal-title":"Int J Stroke."},{"key":"8180_CR12","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1161\/01.STR.0000015625.87603.A7","volume":"33","author":"BC Meyer","year":"2002","unstructured":"Meyer BC, Hemmen TM, Jackson CM, Lyden PD (2002) Modified National Institutes of Health Stroke Scale for use in stroke clinical trials: prospective reliability and validity. Stroke 33:1261\u20131266","journal-title":"Stroke"},{"key":"8180_CR13","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1111\/j.1747-4949.2009.00294.x","volume":"4","author":"BC Meyer","year":"2009","unstructured":"Meyer BC, Lyden PD (2009) The modified National Institutes of Health Stroke Scale: its time has come. Int J Stroke. 4:267\u2013273","journal-title":"Int J Stroke."},{"key":"8180_CR14","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1161\/STROKEAHA.113.003071","volume":"45","author":"N P\u00e9rez de la Ossa","year":"2014","unstructured":"P\u00e9rez de la Ossa N, Carrera D, Gorchs M et al (2014) Design and validation of a prehospital stroke scale to predict large arterial occlusion: the rapid arterial occlusion evaluation scale. Stroke 45:87\u201391","journal-title":"Stroke"},{"key":"8180_CR15","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1161\/01.STR.0000157591.61322.df","volume":"36","author":"OC Singer","year":"2005","unstructured":"Singer OC, Dvorak F, du Mesnil de Rochemont R, Lanfermann H, Sitzer M, Neumann-Haefelin T (2005) A simple 3-item stroke scale: comparison with the National Institutes of Health Stroke Scale and prediction of middle cerebral artery occlusion. Stroke 36:773\u2013776","journal-title":"Stroke"},{"key":"8180_CR16","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1161\/STROKEAHA.114.006837","volume":"46","author":"AH Abdul-Rahim","year":"2015","unstructured":"Abdul-Rahim AH, Fulton RL, Sucharew H, For the VISTA Collaborators et al (2015) National Institutes of Health Stroke Scale Item Profiles as predictor of patient outcome: external validation on independent trial data. Stroke 46:395\u2013400","journal-title":"Stroke"},{"key":"8180_CR17","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1161\/STROKEAHA.114.007850","volume":"2","author":"MR Kesinger","year":"2015","unstructured":"Kesinger MR, Sequeira DJ, Buffalini S, Guyette FX (2015) Comparing National Institutes of Health Stroke Scale among a stroke team and helicopter emergency medical service providers. Stroke 2:575\u2013578","journal-title":"Stroke"},{"key":"8180_CR18","doi-asserted-by":"crossref","first-page":"2801","DOI":"10.1161\/01.STR.0000044166.28481.BC","volume":"33","author":"DL Tirschwell","year":"2002","unstructured":"Tirschwell DL, Longstreth WT Jr, Becker KJ et al (2002) Shortening the NIH Stroke scale for use in the prehospital setting. Stroke 33:2801\u20132806","journal-title":"Stroke"},{"key":"8180_CR19","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1111\/j.1553-2712.1997.tb03665.x","volume":"4","author":"R Kothari","year":"1997","unstructured":"Kothari R, Hall K, Brott T, Broderick J (1997) Early stroke recognition: developing an out-of-hospital NIH Stroke Scale. Acad Emerg Med 4:986\u2013990","journal-title":"Acad Emerg Med"},{"key":"8180_CR20","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1161\/STROKEAHA.115.008804","volume":"46","author":"BS Katz","year":"2015","unstructured":"Katz BS, McMullan JT, Sucharew H, Adeoye O, Broderick JP (2015) Design and validation of a prehospital scale to predict stroke severity: Cincinnati Prehospital Stroke Severity Scale. Stroke 46:1508\u20131512","journal-title":"Stroke"},{"key":"8180_CR21","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1212\/01.wnl.0000237520.88777.71","volume":"67","author":"V Rajajaee","year":"2006","unstructured":"Rajajaee V, Kidwell C, Starkman S et al (2006) Early MRI and outcomes of untreated patients with mild or improving ischemic stroke. Neurology. 67:980\u2013984","journal-title":"Neurology."},{"key":"8180_CR22","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1161\/STR.0b013e318284056a","volume":"44","author":"EC Jauch","year":"2013","unstructured":"Jauch EC, Saver JL, Adams HP Jr, On behalf of the American Heart Association Stroke Council, Council on Cardiovascular Nursing, Council on Peripheral Vascular Disease and Council on Clinical Cardiology, On behalf of the American Heart Association Stroke Council, Council on Cardiovascular Nursing, Council on Peripheral Vascular Disease and Council on Clinical Cardiology et al (2013) Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association\/American Stroke Association. Stroke 44:870\u2013947","journal-title":"Stroke"},{"key":"8180_CR23","first-page":"755","volume":"86","author":"MR Heldner","year":"2015","unstructured":"Heldner MR, Jung S, Zubler C et al (2015) Outcome of patients with occlusions of the internal carotid artery or the main stem of the middle cerebral artery with NIHSS score of less than 5: comparison between thrombolysed and non-thrombolysed patients. JNNP. 86:755\u2013760","journal-title":"JNNP."},{"key":"8180_CR24","first-page":"231","volume":"75","author":"A Arboix","year":"2004","unstructured":"Arboix A, Bell Y, Garc\u00eda-Eroles L et al (2004) Clinical study of 35 patients with dysarthria-clumsy hand syndrome. JNNP. 75:231\u2013234","journal-title":"JNNP."}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-016-8180-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00415-016-8180-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-016-8180-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T11:48:00Z","timestamp":1498304880000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00415-016-8180-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,6]]},"references-count":24,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["8180"],"URL":"https:\/\/doi.org\/10.1007\/s00415-016-8180-6","relation":{},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,6]]}}}