{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T21:27:52Z","timestamp":1783546072072,"version":"3.55.0"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,11,30]],"date-time":"2017-11-30T00:00:00Z","timestamp":1512000000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1092891"],"award-info":[{"award-number":["APP1092891"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1037746"],"award-info":[{"award-number":["1037746"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1007\/s00415-017-8688-4","type":"journal-article","created":{"date-parts":[[2017,11,29]],"date-time":"2017-11-29T23:50:31Z","timestamp":1511999431000},"page":"187-193","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Apathy and its impact on patient outcome in amyotrophic lateral sclerosis"],"prefix":"10.1007","volume":"265","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4295-4366","authenticated-orcid":false,"given":"J.","family":"Caga","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Hsieh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Highton-Williamson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. C.","family":"Zoing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Ramsey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Devenney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. M.","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. C.","family":"Kiernan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,11,30]]},"reference":[{"key":"8688_CR1","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1212\/WNL.46.1.130","volume":"46","author":"MS Mega","year":"1996","unstructured":"Mega MS et al (1996) The spectrum of behavioral changes in Alzheimer\u2019s disease. Neurology 46:130\u2013135","journal-title":"Neurology"},{"key":"8688_CR2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1212\/01.wnl.0000230572.07791.22","volume":"67","author":"L Kirsch-Darrow","year":"2006","unstructured":"Kirsch-Darrow L et al (2006) Dissociating apathy and depression in Parkinson disease. Neurology 67:33\u201338","journal-title":"Neurology"},{"key":"8688_CR3","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1002\/mds.22843","volume":"24","author":"K Dujardin","year":"2009","unstructured":"Dujardin K et al (2009) Apathy may herald cognitive decline and dementia in Parkinson\u2019s disease. Mov Disord 24:2391\u20132397","journal-title":"Mov Disord"},{"key":"8688_CR4","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1093\/brain\/awr179","volume":"134","author":"K Rascovsky","year":"2011","unstructured":"Rascovsky K et al (2011) Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain 134:2456\u20132477","journal-title":"Brain"},{"key":"8688_CR5","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/S1474-4422(13)70036-X","volume":"12","author":"MR Turner","year":"2013","unstructured":"Turner MR et al (2013) Controversies and priorities in amyotrophic lateral sclerosis. Lancet Neurol 12:310\u2013322","journal-title":"Lancet Neurol"},{"key":"8688_CR6","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1080\/21678421.2016.1267768","volume":"18","author":"MJ Strong","year":"2017","unstructured":"Strong MJ et al (2017) Amyotrophic lateral sclerosis\u2014frontotemporal spectrum disorder (ALS-FTSD): Revised diagnostic criteria. Amyotroph Lateral Scler Frontotemporal Degener 18:153\u2013174","journal-title":"Amyotroph Lateral Scler Frontotemporal Degener"},{"key":"8688_CR7","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1111\/ene.12959","volume":"23","author":"J Caga","year":"2016","unstructured":"Caga J et al (2016) Apathy is associated with poor prognosis in amyotrophic lateral sclerosis. Eur J Neurol 23:891\u2013897","journal-title":"Eur J Neurol"},{"key":"8688_CR8","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1111\/j.1468-1331.2010.03016.x","volume":"17","author":"A Chio","year":"2010","unstructured":"Chio A et al (2010) Neurobehavioral symptoms in ALS are negatively related to caregivers\u2019 burden and quality of life. Eur J Neurol 17:1298\u20131303","journal-title":"Eur J Neurol"},{"key":"8688_CR9","first-page":"483","volume":"22","author":"SC Andrews","year":"2017","unstructured":"Andrews SC et al (2017) Which behaviours? Identifying the most common and burdensome behaviour changes in amyotrophic lateral sclerosis Psychol Health Med 22:483\u2013492","journal-title":"Identifying the most common and burdensome behaviour changes in amyotrophic lateral sclerosis Psychol Health Med"},{"key":"8688_CR10","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.4103\/0366-6999.163393","volume":"128","author":"B Cui","year":"2015","unstructured":"Cui B et al (2015) Behavioral symptoms in motor neuron disease and their negative impact on caregiver burden. Chin Med J (Engl) 128:2295\u20132300","journal-title":"Chin Med J (Engl)"},{"key":"8688_CR11","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1007\/s00415-015-7746-z","volume":"262","author":"T Burke","year":"2015","unstructured":"Burke T et al (2015) Caregiver burden in amyotrophic lateral sclerosis: a cross-sectional investigation of predictors. J Neurol 262:1526\u20131532","journal-title":"J Neurol"},{"key":"8688_CR12","doi-asserted-by":"crossref","first-page":"316","DOI":"10.3109\/21678421.2015.1051990","volume":"16","author":"TJ Watermeyer","year":"2015","unstructured":"Watermeyer TJ et al (2015) Impact of disease, cognitive and behavioural factors on caregiver outcome in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener 16:316\u2013323","journal-title":"Amyotroph Lateral Scler Frontotemporal Degener"},{"key":"8688_CR13","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1212\/WNL.0000000000003035","volume":"87","author":"J Rabkin","year":"2016","unstructured":"Rabkin J et al (2016) Cognitive impairment, behavioral impairment, depression, and wish to die in an ALS cohort. Neurology 87:1320\u20131328","journal-title":"Neurology"},{"key":"8688_CR14","doi-asserted-by":"crossref","first-page":"366","DOI":"10.3109\/21678421.2016.1165257","volume":"17","author":"M Bock","year":"2016","unstructured":"Bock M et al (2016) Cognitive-behavioral changes in amyotrophic lateral sclerosis: screening prevalence and impact on patients and caregivers. Amyotroph Lateral Scler Frontotemporal Degener 17:366\u2013373","journal-title":"Amyotroph Lateral Scler Frontotemporal Degener"},{"key":"8688_CR15","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1176\/jnp.3.3.243","volume":"3","author":"RS Marin","year":"1991","unstructured":"Marin RS (1991) Apathy: a neuropsychiatric syndrome. J Neuropsychiatry Clin Neurosci 3:243\u2013254","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"8688_CR16","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1017\/S1041610200006918","volume":"12","author":"SE Starkstein","year":"2000","unstructured":"Starkstein SE (2000) Apathy and withdrawal International Psychogeriatrics 12:135\u2013137","journal-title":"Apathy and withdrawal International Psychogeriatrics"},{"key":"8688_CR17","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1136\/jnnp-2015-310772","volume":"87","author":"R Radakovic","year":"2016","unstructured":"Radakovic R et al (2016) Multidimensional apathy in ALS: validation of the Dimensional Apathy Scale. J Neurol Neurosurg Psychiatry 87:663\u2013669","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"8688_CR18","first-page":"434","volume":"18","author":"G Santangelo","year":"2017","unstructured":"Santangelo G et al (2017) Apathy in amyotrophic lateral sclerosis: insights from Dimensional Apathy Scale Amyotroph Lateral Scler Frontotemporal Degener 18:434\u2013442","journal-title":"Apathy in amyotrophic lateral sclerosis: insights from Dimensional Apathy Scale Amyotroph Lateral Scler Frontotemporal Degener"},{"key":"8688_CR19","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.cortex.2017.06.023","volume":"94","author":"R Radakovic","year":"2017","unstructured":"Radakovic R et al (2017) Multidimensional apathy and executive dysfunction in amyotrophic lateral sclerosis. Cortex 94:142\u2013151","journal-title":"Cortex"},{"key":"8688_CR20","first-page":"942","volume":"377","author":"MC Kiernan","year":"2011","unstructured":"Kiernan MC et al (2011) Amyotrophic lateral sclerosis Lancet 377:942\u2013955","journal-title":"Amyotrophic lateral sclerosis Lancet"},{"issue":"Suppl 2","key":"8688_CR21","doi-asserted-by":"crossref","first-page":"S26","DOI":"10.1007\/BF03160578","volume":"244","author":"M Swash","year":"1997","unstructured":"Swash M (1997) Health outcome and quality-of-life measurements in amyotrophic lateral sclerosis. J Neurol 244(Suppl 2):S26\u2013S29","journal-title":"J Neurol"},{"key":"8688_CR22","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1212\/WNL.0b013e3181bc01a4","volume":"73","author":"RG Miller","year":"2009","unstructured":"Miller RG et al (2009) Practice parameter update: the care of the patient with amyotrophic lateral sclerosis: multidisciplinary care, symptom management, and cognitive\/behavioral impairment (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 73:1227\u20131233","journal-title":"Neurology"},{"key":"8688_CR23","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1080\/146608200300079536","volume":"1","author":"BR Brooks","year":"2000","unstructured":"Brooks BR et al (2000) El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 1:293\u2013299","journal-title":"Amyotroph Lateral Scler Other Motor Neuron Disord"},{"key":"8688_CR24","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1080\/17482960802654364","volume":"10","author":"MJ Strong","year":"2009","unstructured":"Strong MJ et al (2009) Consensus criteria for the diagnosis of frontotemporal cognitive and behavioural syndromes in amyotrophic lateral sclerosis. Amyotroph Lateral Scler 10:131\u2013146","journal-title":"Amyotroph Lateral Scler"},{"key":"8688_CR25","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0022-510X(99)00210-5","volume":"169","author":"JM Cedarbaum","year":"1999","unstructured":"Cedarbaum JM et al (1999) The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III). J Neurol Sci 169:13\u201321","journal-title":"J Neurol Sci"},{"key":"8688_CR26","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1136\/jnnp.63.1.89","volume":"63","author":"SR Moore","year":"1997","unstructured":"Moore SR et al (1997) A self report measure of affective lability. J Neurol Neurosurg Psychiatry 63:89\u201393","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"8688_CR27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000366040","volume":"39","author":"S Hsieh","year":"2015","unstructured":"Hsieh S et al (2015) The Mini-Addenbrooke\u2019s Cognitive Examination: a new assessment tool for dementia. Dement Geriatr Cogn Disord 39:1\u201311","journal-title":"Dement Geriatr Cogn Disord"},{"key":"8688_CR28","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1159\/000351671","volume":"36","author":"S Hsieh","year":"2013","unstructured":"Hsieh S et al (2013) Validation of the Addenbrooke\u2019s Cognitive Examination III in frontotemporal dementia and Alzheimer\u2019s disease. Dement Geriatr Cogn Disord 36:242\u2013250","journal-title":"Dement Geriatr Cogn Disord"},{"key":"8688_CR29","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/0891988715598232","volume":"29","author":"S Hsieh","year":"2016","unstructured":"Hsieh S et al (2016) Cognitive and behavioral symptoms in ALSFTD: detection, differentiation, and progression. J Geriatr Psychiatry Neurol 29:3\u201310","journal-title":"J Geriatr Psychiatry Neurol"},{"key":"8688_CR30","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/S0028-3932(99)00146-3","volume":"38","author":"S Abrahams","year":"2000","unstructured":"Abrahams S et al (2000) Verbal fluency and executive dysfunction in amyotrophic lateral sclerosis (ALS). Neuropsychologia 38:734\u2013747","journal-title":"Neuropsychologia"},{"key":"8688_CR31","doi-asserted-by":"crossref","first-page":"298","DOI":"10.3109\/21678421.2014.896927","volume":"15","author":"E Mioshi","year":"2014","unstructured":"Mioshi E et al (2014) A novel tool to detect behavioural symptoms in ALS. Amyotroph Lateral Scler Frontotemporal Degener 15:298\u2013304","journal-title":"Amyotroph Lateral Scler Frontotemporal Degener"},{"key":"8688_CR32","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","volume":"67","author":"AS Zigmond","year":"1983","unstructured":"Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67:361\u2013370","journal-title":"Acta Psychiatr Scand"},{"key":"8688_CR33","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1111\/j.1468-1331.2007.01843.x","volume":"14","author":"P Wicks","year":"2007","unstructured":"Wicks P et al (2007) Prevalence of depression in a 12-month consecutive sample of patients with ALS. Eur J Neurol 14:993\u20131001","journal-title":"Eur J Neurol"},{"key":"8688_CR34","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0165-1781(91)90040-V","volume":"38","author":"RS Marin","year":"1991","unstructured":"Marin RS, Biedrzycki RC, Firinciogullari S (1991) Reliability and validity of the Apathy Evaluation Scale. Psychiatry Res 38:143\u2013162","journal-title":"Psychiatry Res"},{"key":"8688_CR35","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1176\/jnp.2007.19.1.57","volume":"19","author":"DE Clarke","year":"2007","unstructured":"Clarke DE et al (2007) Apathy in dementia: an examination of the psychometric properties of the apathy evaluation scale. J Neuropsychiatry Clin Neurosci 19:57\u201364","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"8688_CR36","unstructured":"International Wellbeing Group (2006) Personal wellbeing index. Australian centre on quality of life, Deakin University, Melbourne. \n                        http:\/\/www.deakin.edu.au\/research\/acqol\/instruments\/wellbeing_index.htm"},{"key":"8688_CR37","unstructured":"IBM Corp, IBM SPSS Statistics for Macintosh, Version 24.0. Released 2016, Armonk, NY: IBM Corp"},{"key":"8688_CR38","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1212\/WNL.58.2.320","volume":"58","author":"MB Bromberg","year":"2002","unstructured":"Bromberg MB, Forshew DA (2002) Comparison of instruments addressing quality of life in patients with ALS and their caregivers. Neurology 58:320\u2013322","journal-title":"Neurology"},{"key":"8688_CR39","doi-asserted-by":"crossref","first-page":"456","DOI":"10.3109\/17482960802444840","volume":"10","author":"SH Felgoise","year":"2009","unstructured":"Felgoise SH et al (2009) The SEIQoL-DW for assessing quality of life in ALS: strengths and limitations. Amyotroph Lateral Scler 10:456\u2013462","journal-title":"Amyotroph Lateral Scler"},{"key":"8688_CR40","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1080\/00207594.2012.691977","volume":"48","author":"F Pagnini","year":"2013","unstructured":"Pagnini F (2013) Psychological wellbeing and quality of life in amyotrophic lateral sclerosis: a review. Int J Psychol 48:194\u2013205","journal-title":"Int J Psychol"},{"key":"8688_CR41","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1212\/01.WNL.0000042781.22278.0A","volume":"60","author":"JS Lou","year":"2003","unstructured":"Lou JS et al (2003) Fatigue and depression are associated with poor quality of life in ALS. Neurology 60:122\u2013123","journal-title":"Neurology"},{"key":"8688_CR42","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1136\/jnnp.2003.033100","volume":"75","author":"A Chio","year":"2004","unstructured":"Chio A et al (2004) A cross sectional study on determinants of quality of life in ALS. J Neurol Neurosurg Psychiatry 75:1597\u20131601","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"8688_CR43","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1212\/01.wnl.0000257093.53430.a8","volume":"68","author":"A Gauthier","year":"2007","unstructured":"Gauthier A et al (2007) A longitudinal study on quality of life and depression in ALS patient-caregiver couples. Neurology 68:923\u2013926","journal-title":"Neurology"},{"key":"8688_CR44","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1176\/ajp.147.1.22","volume":"147","author":"RS Marin","year":"1990","unstructured":"Marin RS (1990) Differential diagnosis and classification of apathy. Am J Psychiatry 147:22\u201330","journal-title":"Am J Psychiatry"},{"key":"8688_CR45","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/S1474-4422(15)00019-8","volume":"14","author":"J Pagonabarraga","year":"2015","unstructured":"Pagonabarraga J et al (2015) Apathy in Parkinson\u2019s disease: clinical features, neural substrates, diagnosis, and treatment. Lancet Neurol 14:518\u2013531","journal-title":"Lancet Neurol"},{"key":"8688_CR46","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1046\/j.1532-5415.2001.49282.x","volume":"49","author":"AM Landes","year":"2001","unstructured":"Landes AM et al (2001) Apathy in Alzheimer\u2019s disease. J Am Geriatr Soc 49:1700\u20131707","journal-title":"J Am Geriatr Soc"},{"key":"8688_CR47","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1093\/cercor\/bhj043","volume":"16","author":"R Levy","year":"2006","unstructured":"Levy R, Dubois B (2006) Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits. Cereb Cortex 16:916\u2013928","journal-title":"Cereb Cortex"},{"key":"8688_CR48","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1007\/s00415-010-5640-2","volume":"257","author":"A Palmieri","year":"2010","unstructured":"Palmieri A et al (2010) Right hemisphere dysfunction and emotional processing in ALS: an fMRI study. J Neurol 257:1970\u20131978","journal-title":"J Neurol"},{"key":"8688_CR49","doi-asserted-by":"crossref","first-page":"52","DOI":"10.3109\/17482968.2010.521842","volume":"12","author":"SC Woolley","year":"2011","unstructured":"Woolley SC et al (2011) Neuroanatomical correlates of apathy in ALS using 4 Tesla diffusion tensor MRI. Amyotroph Lateral Scler 12:52\u201358","journal-title":"Amyotroph Lateral Scler"},{"key":"8688_CR50","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.jns.2011.05.025","volume":"307","author":"M Tsujimoto","year":"2011","unstructured":"Tsujimoto M et al (2011) Behavioral changes in early ALS correlate with voxel-based morphometry and diffusion tensor imaging. J Neurol Sci 307:34\u201340","journal-title":"J Neurol Sci"},{"key":"8688_CR51","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1136\/jnnp-2012-302817","volume":"83","author":"M Elamin","year":"2012","unstructured":"Elamin M et al (2012) Social cognition in neurodegenerative disorders: a systematic review. J Neurol Neurosurg Psychiatry 83:1071\u20131079","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"8688_CR52","first-page":"9","volume":"15","author":"S Abrahams","year":"2014","unstructured":"Abrahams S et al (2014) Screening for cognition and behaviour changes in ALS Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 15:9\u201314","journal-title":"Screening for cognition and behaviour changes in ALS Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration"},{"key":"8688_CR53","doi-asserted-by":"crossref","first-page":"A177","DOI":"10.1212\/WNL.0b013e3181c919ee","volume":"74","author":"Z Simmons","year":"2010","unstructured":"Simmons Z et al (2010) Validation of a Shorter ALS-Specific Quality of Life Instrument: the ALSSQOL-R. Neurology 74:A177\u2013A178","journal-title":"Neurology"}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00415-017-8688-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-017-8688-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-017-8688-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,9]],"date-time":"2018-01-09T05:02:49Z","timestamp":1515474169000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00415-017-8688-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,30]]},"references-count":53,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["8688"],"URL":"https:\/\/doi.org\/10.1007\/s00415-017-8688-4","relation":{},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,30]]}}}