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Stojkovic has received speaker honoraria from Actavis and research grant from the Ministry of Education and Science, Republic of Serbia, as well as Alzheimer\u2019s Association International Research Grant. E. Stefanova has received speaker honoraria from Novartis, Glaxo Smith Kline and Boehringer Ingelheim, research grant from the Ministry of Education and Science, Republic of Serbia, as well as Alzheimer\u2019s Association International Research Grant. I. Soldatovic. Declarations of interest: none. V. Markovic has received research grants from the Ministry of Education and Science, Republic of Serbia. I. Stankovic has received research grants from the Ministry of Education and Science, Republic of Serbia. I Petrovic has received speaker honoraria from Boehringer Ingelheim, GSK, El pharma, Roche, Actavis and research grants from the Ministry of Education and Science, Republic of Serbia. F. Agosta is Section Editor of NeuroImage: Clinical; has received speaker honoraria from Biogen Idec, Novartis, and ExceMED\u2014Excellence in Medical Education; and receives or has received research supports from the Italian Ministry of Health, AriSLA (Fondazione Italiana di Ricerca per la SLA), and the European Research Council. S. Galantucci. Declarations of interest: none. M. Filippi is Editor-in-Chief of the Journal of Neurology; serves on a scientific advisory board for Teva Pharmaceutical Industries; has received compensation for consulting services and\/or speaking activities from Biogen Idec, ExceMED, Novartis, and Teva Pharmaceutical Industries; and receives research support from Biogen Idec, Teva Pharmaceutical Industries, Novartis, Italian Ministry of Health, Fondazione Italiana Sclerosi Multipla, Cure PSP, Alzheimer\u2019s Drug Discovery Foundation (ADDF), the Jacques and Gloria Gossweiler Foundation (Switzerland), and ARiSLA (Fondazione Italiana di Ricerca per la SLA). V. Kostic serves on the editorial board of the Journal of Neurology; has received research grants from Ministry of Education and Science, Republic of Serbia, and the Serbian Academy of Science and Arts; and receives research support from Valeant, Stada, Novartis, and Boehringer Ingelheim, and speaker honoraria from Novartis and Boehringer Ingelheim.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The local Ethical Committee (School of Medicine, University of Belgrade, Serbia) approved the study protocol and all participants signed written informed consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}