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Marie-Laure Welter received research support from the \u2018Institut du Cerveau et de la Moelle. Epini\u00e8re\u2019 (ICM) Foundation and the Agence Nationale de la Recherche. Nicolas Termoz received research support from the Laboratoire CeRSM\u2014EA 2931. Peter Bede is supported by the Health Research Board (HRB\u2014Ireland; HRB EIA-2017-019), the Irish Institute of Clinical Neuroscience IICN\u2014Novartis Ireland Research (IICN\u20142016), the Iris O\u2019Brien Foundation, the Perrigo Clinician-Scientist Research Fellowship, and the Research Motor Neuron (RMN-Ireland) Foundation Ireland. Pierre-Fran\u00e7ois Pradat received research support from the French Association for Research in ALS (ARSla), the Institute for Research in Spinal Cord and Brain (IRME), the French Association for Myopathie (AFM-Telethon), Paris Institute of Translational Neuroscience (IHU-A-ICM), the Thierry Latran foundation, the Target ALS foundation and the Institut National pour la Sant\u00e9 et la Recherche M\u00e9dicale (INSERM). Giovanni de Marco received research support from the Laboratoire CeRSM\u2014EA 2931 and COMUE Universit\u00e9 Paris Lumi\u00e8res.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"All procedures performed in this study were fully approved by the local, institutional ethics committee (CPP Ile-de-France Paris VI; INSERM promotion RBM C12-13) and were in accordance with the 1964 Helsinki Declaration and its later amendments. This study does not involve any methods or experiments with animals.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"All study participants provided informed consent prior to inclusion in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}