{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:09:22Z","timestamp":1790730562289,"version":"4.1.0"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2018,8,6]],"date-time":"2018-08-06T00:00:00Z","timestamp":1533513600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1007\/s00415-018-8993-6","type":"journal-article","created":{"date-parts":[[2018,8,6]],"date-time":"2018-08-06T00:49:41Z","timestamp":1533516581000},"page":"2302-2311","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Compromised tDCS-induced facilitation of motor consolidation in patients with multiple sclerosis"],"prefix":"10.1007","volume":"265","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7357-713X","authenticated-orcid":false,"given":"Jost-Julian","family":"Rumpf","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Dietrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muriel","family":"Stoppe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Fricke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Weise","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Then Bergh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Classen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,8,6]]},"reference":[{"issue":"1","key":"8993_CR1","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.neuron.2006.09.011","volume":"52","author":"SL Hauser","year":"2006","unstructured":"Hauser SL, Oksenberg JR (2006) The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration. Neuron 52(1):61\u201376. \n                    https:\/\/doi.org\/10.1016\/j.neuron.2006.09.011","journal-title":"Neuron"},{"issue":"12","key":"8993_CR2","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1038\/nrn2023","volume":"7","author":"SG Waxman","year":"2006","unstructured":"Waxman SG (2006) Axonal conduction and injury in multiple sclerosis: the role of sodium channels. Nat Rev Neurosci 7(12):932\u2013941. \n                    https:\/\/doi.org\/10.1038\/nrn2023","journal-title":"Nat Rev Neurosci"},{"issue":"1","key":"8993_CR3","doi-asserted-by":"publisher","first-page":"85","DOI":"10.3174\/ajnr.A2238","volume":"32","author":"RJ Fox","year":"2011","unstructured":"Fox RJ, Cronin T, Lin J, Wang X, Sakaie K, Ontaneda D, Mahmoud SY, Lowe MJ, Phillips MD (2011) Measuring Myelin Repair and Axonal Loss with Diffusion Tensor Imaging. Am J Neuroradiol 32(1):85\u201391. \n                    https:\/\/doi.org\/10.3174\/ajnr.A2238","journal-title":"Am J Neuroradiol"},{"key":"8993_CR4","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.neuroscience.2014.05.043","volume":"283","author":"D Zeller","year":"2014","unstructured":"Zeller D, Classen J (2014) Plasticity of the Motor System in Multiple Sclerosis. Neuroscience 283:222\u2013230. \n                    https:\/\/doi.org\/10.1016\/j.neuroscience.2014.05.043","journal-title":"Neuroscience"},{"issue":"3","key":"8993_CR5","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/S0028-3932(02)00158-6","volume":"41","author":"J Doyon","year":"2003","unstructured":"Doyon J, Penhune V, Ungerleider LG (2003) Distinct contribution of the cortico-striatal and cortico-cerebellar systems to motor skill learning. Neuropsychologia 41(3):252\u2013262","journal-title":"Neuropsychologia"},{"issue":"49","key":"8993_CR6","doi-asserted-by":"publisher","first-page":"13413","DOI":"10.1523\/JNEUROSCI.2570-07.2007","volume":"27","author":"A Hadipour-Niktarash","year":"2007","unstructured":"Hadipour-Niktarash A, Lee CK, Desmond JE, Shadmehr R (2007) Impairment of retention but not acquisition of a visuomotor skill through time-dependent disruption of primary motor cortex. J Neurosci 27(49):13413\u201313419. \n                    https:\/\/doi.org\/10.1523\/JNEUROSCI.2570-07.2007","journal-title":"J Neurosci"},{"issue":"6872","key":"8993_CR7","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1038\/nature712","volume":"415","author":"W Muellbacher","year":"2002","unstructured":"Muellbacher W, Ziemann U, Wissel J, Dang N, Kofler M, Facchini S, Boroojerdi B, Poewe W, Hallett M (2002) Early consolidation in human primary motor cortex. Nature 415(6872):640\u2013644. \n                    https:\/\/doi.org\/10.1038\/nature712","journal-title":"Nature"},{"issue":"27","key":"8993_CR8","doi-asserted-by":"publisher","first-page":"6372","DOI":"10.1523\/JNEUROSCI.1851-05.2005","volume":"25","author":"EM Robertson","year":"2005","unstructured":"Robertson EM, Press DZ, Pascual-Leone A (2005) Off-line learning and the primary motor cortex. J Neurosci 25(27):6372\u20136378. \n                    https:\/\/doi.org\/10.1523\/JNEUROSCI.1851-05.2005","journal-title":"J Neurosci"},{"issue":"3","key":"8993_CR9","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1073\/pnas.95.3.861","volume":"95","author":"A Karni","year":"1998","unstructured":"Karni A, Meyer G, Rey-Hipolito C, Jezzard P, Adams MM, Turner R, Ungerleider LG (1998) The acquisition of skilled motor performance: Fast and slow experience-driven changes in primary motor cortex. P Natl Acad Sci USA 95(3):861\u2013868. \n                    https:\/\/doi.org\/10.1073\/pnas.95.3.861","journal-title":"P Natl Acad Sci USA"},{"issue":"9","key":"8993_CR10","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1038\/nrn3315","volume":"13","author":"N Censor","year":"2012","unstructured":"Censor N, Sagi D, Cohen LG (2012) Common mechanisms of human perceptual and motor learning. Nat Rev Neurosci 13(9):658\u2013664. \n                    https:\/\/doi.org\/10.1038\/nrn3315","journal-title":"Nat Rev Neurosci"},{"issue":"9","key":"8993_CR11","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1212\/WNL.0b013e3181d31dcf","volume":"74","author":"D Zeller","year":"2010","unstructured":"Zeller D, Kampe KA, Biller A, Stefan K, Gentner R, Schutz A, Bartsch A, Bendszus M, Toyka KV, Rieckmann P, Classen J (2010) Rapid-onset central motor plasticity in multiple sclerosis. Neurology 74(9):728\u2013735. \n                    https:\/\/doi.org\/10.1212\/WNL.0b013e3181d31dcf","journal-title":"Neurology"},{"issue":"1","key":"8993_CR12","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1177\/1352458510381257","volume":"17","author":"V Tomassini","year":"2011","unstructured":"Tomassini V, Johansen-Berg H, Leonardi L, Paixao L, Jbabdi S, Palace J, Pozzilli C, Matthews PM (2011) Preservation of motor skill learning in patients with multiple sclerosis. Mult Scler J 17(1):103\u2013115. \n                    https:\/\/doi.org\/10.1177\/1352458510381257","journal-title":"Mult Scler J"},{"issue":"3","key":"8993_CR13","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1111\/j.1469-7793.2000.t01-1-00633.x","volume":"527","author":"MA Nitsche","year":"2000","unstructured":"Nitsche MA, Paulus W (2000) Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation. J Physiol Lond 527(3):633\u2013639. \n                    https:\/\/doi.org\/10.1111\/j.1469-7793.2000.t01-1-00633.x","journal-title":"J Physiol Lond"},{"issue":"4","key":"8993_CR14","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1016\/j.clinph.2017.01.004","volume":"128","author":"ER Buch","year":"2017","unstructured":"Buch ER, Santarnecchi E, Antal A, Born J, Celnik PA, Classen J, Gerloff C, Hallett M, Hummel FC, Nitsche MA, Pascual-Leone A, Paulus WJ, Reis J, Robertson EM, Rothwell JC, Sandrini M, Schambra HM, Wassermann EM, Ziemann U, Cohen LG (2017) Effects of tDCS on motor learning and memory formation: a consensus and critical position paper. Clin Neurophysiol 128(4):589\u2013603. \n                    https:\/\/doi.org\/10.1016\/j.clinph.2017.01.004","journal-title":"Clin Neurophysiol"},{"issue":"10","key":"8993_CR15","doi-asserted-by":"publisher","first-page":"2888","DOI":"10.1111\/j.1460-9568.2004.03367.x","volume":"19","author":"A Antal","year":"2004","unstructured":"Antal A, Nitsche MA, Kincses TZ, Kruse W, Hoffmann KP, Paulus W (2004) Facilitation of visuo-motor learning by transcranial direct current stimulation of the motor and extrastriate visual areas in humans. Eur J Neurosci 19(10):2888\u20132892. \n                    https:\/\/doi.org\/10.1111\/j.1460-9568.2004.03367.x","journal-title":"Eur J Neurosci"},{"issue":"12","key":"8993_CR16","doi-asserted-by":"publisher","first-page":"2160","DOI":"10.1016\/j.neurobiolaging.2008.12.008","volume":"31","author":"FC Hummel","year":"2010","unstructured":"Hummel FC, Heise K, Celnik P, Floel A, Gerloff C, Cohen LG (2010) Facilitating skilled right hand motor function in older subjects by anodal polarization over the left primary motor cortex. Neurobiol Aging 31(12):2160\u20132168. \n                    https:\/\/doi.org\/10.1016\/j.neurobiolaging.2008.12.008","journal-title":"Neurobiol Aging"},{"issue":"1","key":"8993_CR17","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1002\/ana.23761","volume":"73","author":"M Zimerman","year":"2013","unstructured":"Zimerman M, Nitsch M, Giraux P, Gerloff C, Cohen LG, Hummel FC (2013) Neuroenhancement of the aging brain: restoring skill acquisition in old subjects. Ann Neurol 73(1):10\u201315. \n                    https:\/\/doi.org\/10.1002\/ana.23761","journal-title":"Ann Neurol"},{"issue":"4","key":"8993_CR18","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1162\/089892903321662994","volume":"15","author":"MA Nitsche","year":"2003","unstructured":"Nitsche MA, Schauenburg A, Lang N, Liebetanz D, Exner C, Paulus W, Tergau F (2003) Facilitation of implicit motor learning by weak transcranial direct current stimulation of the primary motor cortex in the human. J Cogn Neurosci 15(4):619\u2013626. \n                    https:\/\/doi.org\/10.1162\/089892903321662994","journal-title":"J Cogn Neurosci"},{"key":"8993_CR19","doi-asserted-by":"publisher","DOI":"10.1177\/1545968318769164","author":"M Hamoudi","year":"2018","unstructured":"Hamoudi M, Schambra HM, Fritsch B, Schoechlin-Marx A, Weiller C, Cohen LG, Reis J (2018) Transcranial direct current stimulation enhances motor skill learning but not generalization in chronic stroke. Neurorehabil Neural Repair. \n                    https:\/\/doi.org\/10.1177\/1545968318769164\n                    \n                   (1545968318769164)","journal-title":"Neurorehabil Neural Repair"},{"issue":"5","key":"8993_CR20","doi-asserted-by":"publisher","first-page":"1590","DOI":"10.1073\/pnas.0805413106","volume":"106","author":"J Reis","year":"2009","unstructured":"Reis J, Schambra HM, Cohen LG, Buch ER, Fritsch B, Zarahn E, Celnik PA, Krakauer JW (2009) Noninvasive cortical stimulation enhances motor skill acquisition over multiple days through an effect on consolidation. Proc Natl Acad Sci USA 106(5):1590\u20131595. \n                    https:\/\/doi.org\/10.1073\/pnas.0805413106","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"8993_CR21","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1093\/cercor\/bht208","volume":"25","author":"J Reis","year":"2015","unstructured":"Reis J, Fischer JT, Prichard G, Weiller C, Cohen LG, Fritsch B (2015) Time-but not sleep-dependent consolidation of tDCS-enhanced visuomotor skills. Cereb Cortex 25(1):109\u2013117. \n                    https:\/\/doi.org\/10.1093\/cercor\/bht208","journal-title":"Cereb Cortex"},{"issue":"2","key":"8993_CR22","doi-asserted-by":"publisher","first-page":"1134","DOI":"10.1152\/jn.00661.2009","volume":"104","author":"F Tecchio","year":"2010","unstructured":"Tecchio F, Zappasodi F, Assenza G, Tombini M, Vollaro S, Barbati G, Rossini PM (2010) Anodal transcranial direct current stimulation enhances procedural consolidation. J Neurophysiol 104(2):1134\u20131140. \n                    https:\/\/doi.org\/10.1152\/jn.00661.2009","journal-title":"J Neurophysiol"},{"key":"8993_CR23","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2016.00004","author":"V Krause","year":"2016","unstructured":"Krause V, Meier A, Dinkelbach L, Pollok B (2016) Beta band transcranial alternating (tACS) and direct current stimulation (tDCS) applied after initial learning facilitate retrieval of a motor sequence. Front Behav Neurosci. \n                    https:\/\/doi.org\/10.3389\/fnbeh.2016.00004","journal-title":"Front Behav Neurosci"},{"key":"8993_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.neurobiolaging.2016.09.003","volume":"49","author":"JJ Rumpf","year":"2017","unstructured":"Rumpf JJ, Wegscheider M, Hinselmann K, Fricke C, King BR, Weise D, Klann J, Binkofski F, Buccino G, Karni A, Doyon J, Classen J (2017) Enhancement of motor consolidation by post-training transcranial direct current stimulation in older people. Neurobiol Aging 49:1\u20138. \n                    https:\/\/doi.org\/10.1016\/j.neurobiolaging.2016.09.003","journal-title":"Neurobiol Aging"},{"key":"8993_CR25","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2013.00142","author":"BR King","year":"2013","unstructured":"King BR, Fogel SM, Albouy G, Doyon J (2013) Neural correlates of the age-related changes in motor sequence learning and motor adaptation in older adults. Front Hum Neurosci. \n                    https:\/\/doi.org\/10.3389\/fnhum.2013.00142","journal-title":"Front Hum Neurosci"},{"issue":"11","key":"8993_CR26","doi-asserted-by":"publisher","first-page":"1444","DOI":"10.1212\/Wnl.33.11.1444","volume":"33","author":"JF Kurtzke","year":"1983","unstructured":"Kurtzke JF (1983) Rating neurologic impairment in multiple-sclerosis\u2014an expanded disability status scale (Edss). Neurology 33(11):1444\u20131452. doi:\n                    https:\/\/doi.org\/10.1212\/Wnl.33.11.1444","journal-title":"Neurology"},{"issue":"4","key":"8993_CR27","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1177\/135245859900500409","volume":"5","author":"JS Fischer","year":"1999","unstructured":"Fischer JS, Rudick RA, Cutter GR, Reingold SC, Assessment NMSCO (1999) The multiple sclerosis functional composite measure (MSFC): an integrated approach to MS clinical outcome assessment. Mult Scler 5(4):244\u2013250. doi:\n                    https:\/\/doi.org\/10.1177\/135245859900500409","journal-title":"Mult Scler"},{"key":"8993_CR28","first-page":"83","volume-title":"Learning disorders","author":"A Smith","year":"1968","unstructured":"Smith A (1968) The symbol-digit modalities test: a neuropsychologic test of learning and other cerebral disorders. In: Helmuth J (ed) Learning disorders. Special Child Publications, Seattle, pp\u00a083\u201391"},{"issue":"2","key":"8993_CR29","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1002\/ana.22366","volume":"69","author":"CH Polman","year":"2011","unstructured":"Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, Filippi M, Fujihara K, Havrdova E, Hutchinson M, Kappos L, Lublin FD, Montalban X, O\u2019Connor P, Sandberg-Wollheim M, Thompson AJ, Waubant E, Weinshenker B, Wolinsky JS (2011) Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol 69(2):292\u2013302. \n                    https:\/\/doi.org\/10.1002\/ana.22366","journal-title":"Ann Neurol"},{"issue":"3","key":"8993_CR30","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1207\/s15327752jpa6703_13","volume":"67","author":"AT Beck","year":"1996","unstructured":"Beck AT, Steer RA, Ball R, Ranieri W (1996) Comparison of beck depression inventories-IA and -II in psychiatric outpatients. J Pers Assess 67(3):588\u2013597. \n                    https:\/\/doi.org\/10.1207\/s15327752jpa6703_13","journal-title":"J Pers Assess"},{"issue":"1","key":"8993_CR31","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s002210000449","volume":"134","author":"RQ Cui","year":"2000","unstructured":"Cui RQ, Huter D, Egkher A, Lang W, Lindinger G, Deecke L (2000) High resolution DC-EEG mapping of the Bereitschaftspotential preceding simple or complex bimanual sequential finger movement. Exp Brain Res 134(1):49\u201357","journal-title":"Exp Brain Res"},{"issue":"3","key":"8993_CR32","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.brs.2008.06.004","volume":"1","author":"MA Nitsche","year":"2008","unstructured":"Nitsche MA, Cohen LG, Wassermann EM, Priori A, Lang N, Antal A, Paulus W, Hummel F, Boggio PS, Fregni F, Pascual-Leone A (2008) Transcranial direct current stimulation: state of the art 2008. Brain Stimul 1(3):206\u2013223. \n                    https:\/\/doi.org\/10.1016\/j.brs.2008.06.004\n                    \n                   pii .","journal-title":"Brain Stimul"},{"issue":"4","key":"8993_CR33","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1016\/j.clinph.2005.12.003","volume":"117","author":"PC Gandiga","year":"2006","unstructured":"Gandiga PC, Hummel FC, Cohen LG (2006) Transcranial DC stimulation (tDCS): a tool for double-blind sham-controlled clinical studies in brain stimulation. Clin Neurophysiol 117(4):845\u2013850. \n                    https:\/\/doi.org\/10.1016\/j.clinph.2005.12.003\n                    \n                   pii].","journal-title":"Clin Neurophysiol"},{"issue":"2","key":"8993_CR34","doi-asserted-by":"publisher","first-page":"1588","DOI":"10.1093\/cercor\/bhv347","volume":"27","author":"BR King","year":"2017","unstructured":"King BR, Saucier P, Albouy G, Fogel SM, Rumpf JJ, Klann J, Buccino G, Binkofski F, Classen J, Karni A, Doyon J (2017) Cerebral activation during initial motor learning forecasts subsequent sleep-facilitated memory consolidation in older adults. Cereb Cortex 27(2):1588\u20131601. \n                    https:\/\/doi.org\/10.1093\/cercor\/bhv347","journal-title":"Cereb Cortex"},{"issue":"7","key":"8993_CR35","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1038\/nrn1426","volume":"5","author":"EM Robertson","year":"2004","unstructured":"Robertson EM, Pascual-Leone A, Miall RC (2004) Current concepts in procedural consolidation. Nat Rev Neurosci 5(7):576\u2013582. \n                    https:\/\/doi.org\/10.1038\/nrn1426","journal-title":"Nat Rev Neurosci"},{"issue":"3","key":"8993_CR36","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1177\/1545968306294913","volume":"21","author":"L Leocani","year":"2007","unstructured":"Leocani L, Comi E, Annovazzi P, Rovaris M, Rossi P, Cursi M, Comola M, Martinelli V, Comi G (2007) Impaired short-term motor learning in multiple sclerosis: evidence from virtual reality. Neurorehabil Neural Repair 21(3):273\u2013278. \n                    https:\/\/doi.org\/10.1177\/1545968306294913","journal-title":"Neurorehabil Neural Repair"},{"issue":"2","key":"8993_CR37","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1016\/j.neuroimage.2008.12.006","volume":"45","author":"L Mancini","year":"2009","unstructured":"Mancini L, Ciccarelli O, Manfredonia F, Thornton JS, Agosta F, Barkhof F, Beckmann C, De Stefano N, Enzinger C, Fazekas F, Filippi M, Gass A, Hirsch JG, Johansen-Berg H, Kappos L, Korteweg T, Manson SC, Marino S, Matthews PM, Montalban X, Palace J, Polman C, Rocca M, Ropele S, Rovira A, Wegner C, Friston K, Thompson A, Yousry T (2009) Short-term adaptation to a simple motor task: a physiological process preserved in multiple sclerosis. Neuroimage 45(2):500\u2013511. \n                    https:\/\/doi.org\/10.1016\/j.neuroimage.2008.12.006","journal-title":"Neuroimage"},{"issue":"2","key":"8993_CR38","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1016\/j.neuroimage.2011.04.037","volume":"57","author":"L Bonzano","year":"2011","unstructured":"Bonzano L, Tacchino A, Roccatagliata L, Sormani MP, Mancardi GL, Bove M (2011) Impairment in explicit visuomotor sequence learning is related to loss of microstructural integrity of the corpus callosum in multiple sclerosis patients with minimal disability. Neuroimage 57(2):495\u2013501. \n                    https:\/\/doi.org\/10.1016\/j.neuroimage.2011.04.037","journal-title":"Neuroimage"},{"key":"8993_CR39","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.brainres.2014.08.031","volume":"1585","author":"A Tacchino","year":"2014","unstructured":"Tacchino A, Bove M, Roccatagliata L, Luigi Mancardi G, Uccelli A, Bonzano L (2014) Selective impairments of motor sequence learning in multiple sclerosis patients with minimal disability. Brain Res 1585:91\u201398. \n                    https:\/\/doi.org\/10.1016\/j.brainres.2014.08.031","journal-title":"Brain Res"},{"issue":"2","key":"8993_CR40","doi-asserted-by":"publisher","first-page":"293","DOI":"10.3233\/Rnn-130348","volume":"32","author":"RLJ Meesen","year":"2014","unstructured":"Meesen RLJ, Thijs H, Leenus DJF, Cuypers K (2014) A single session of 1 mA anodal tDCS-supported motor training does not improve motor performance in patients with multiple sclerosis. Restor Neurol Neuros 32(2):293\u2013300. \n                    https:\/\/doi.org\/10.3233\/Rnn-130348","journal-title":"Restor Neurol Neuros"},{"issue":"6","key":"8993_CR41","doi-asserted-by":"publisher","first-page":"e67344","DOI":"10.1371\/journal.pone.0067344","volume":"8","author":"K Cuypers","year":"2013","unstructured":"Cuypers K, Leenus DJ, van den Berg FE, Nitsche MA, Thijs H, Wenderoth N, Meesen RL (2013) Is motor learning mediated by tDCS intensity? PLoS One 8(6):e67344. \n                    https:\/\/doi.org\/10.1371\/journal.pone.0067344","journal-title":"PLoS One"},{"issue":"5","key":"8993_CR42","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1016\/j.neuropsychologia.2011.02.009","volume":"49","author":"CJ Stagg","year":"2011","unstructured":"Stagg CJ, Jayaram G, Pastor D, Kincses ZT, Matthews PM, Johansen-Berg H (2011) Polarity and timing-dependent effects of transcranial direct current stimulation in explicit motor learning. Neuropsychologia 49(5):800\u2013804. \n                    https:\/\/doi.org\/10.1016\/j.neuropsychologia.2011.02.009","journal-title":"Neuropsychologia"},{"key":"8993_CR43","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1186\/1471-2377-12-92","volume":"12","author":"D Zeller","year":"2012","unstructured":"Zeller D, Dang SY, Weise D, Rieckmann P, Toyka KV, Classen J (2012) Excitability decreasing central motor plasticity is retained in multiple sclerosis patients. BMC Neurol 12:92. \n                    https:\/\/doi.org\/10.1186\/1471-2377-12-92","journal-title":"BMC Neurol"},{"key":"8993_CR44","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.neulet.2013.09.004","volume":"554","author":"K Cuypers","year":"2013","unstructured":"Cuypers K, Leenus DJF, Van Wijmeersch B, Thijs H, Levin O, Swinnen SP, Meesen RLJ (2013) Anodal tDCS increases corticospinal output and projection strength in multiple sclerosis. Neurosci Lett 554:151\u2013155. \n                    https:\/\/doi.org\/10.1016\/j.neulet.2013.09.004","journal-title":"Neurosci Lett"},{"key":"8993_CR45","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/j.neuroimage.2012.11.020","volume":"67","author":"RM Hardwick","year":"2013","unstructured":"Hardwick RM, Rottschy C, Miall RC, Eickhoff SB (2013) A quantitative meta-analysis and review of motor learning in the human brain. Neuroimage 67:283\u2013297. \n                    https:\/\/doi.org\/10.1016\/j.neuroimage.2012.11.020","journal-title":"Neuroimage"},{"issue":"2","key":"8993_CR46","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.neuron.2008.02.008","volume":"58","author":"G Albouy","year":"2008","unstructured":"Albouy G, Sterpenich V, Balteau E, Vandewalle G, Desseilles M, Dang-Vu T, Darsaud A, Ruby P, Luppi PH, Degueldre C, Peigneux P, Luxen A, Maquet P (2008) Both the hippocampus and striatum are involved in consolidation of motor sequence memory. Neuron 58(2):261\u2013272. \n                    https:\/\/doi.org\/10.1016\/j.neuron.2008.02.008","journal-title":"Neuron"},{"issue":"41","key":"8993_CR47","doi-asserted-by":"publisher","first-page":"17839","DOI":"10.1073\/pnas.1013176107","volume":"107","author":"K Debas","year":"2010","unstructured":"Debas K, Carrier J, Orban P, Barakat M, Lungu O, Vandewalle G, Hadj Tahar A, Bellec P, Karni A, Ungerleider LG, Benali H, Doyon J (2010) Brain plasticity related to the consolidation of motor sequence learning and motor adaptation. Proc Natl Acad Sci USA 107(41):17839\u201317844. \n                    https:\/\/doi.org\/10.1073\/pnas.1013176107","journal-title":"Proc Natl Acad Sci USA"},{"key":"8993_CR48","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.neuroimage.2014.05.022","volume":"99","author":"K Debas","year":"2014","unstructured":"Debas K, Carrier J, Barakat M, Marrelec G, Bellec P, Hadj Tahar A, Karni A, Ungerleider LG, Benali H, Doyon J (2014) Off-line consolidation of motor sequence learning results in greater integration within a cortico-striatal functional network. Neuroimage 99:50\u201358. \n                    https:\/\/doi.org\/10.1016\/j.neuroimage.2014.05.022","journal-title":"Neuroimage"},{"issue":"20","key":"8993_CR49","doi-asserted-by":"publisher","first-page":"3086","DOI":"10.1016\/j.cub.2017.09.020","volume":"27","author":"MR Krause","year":"2017","unstructured":"Krause MR, Zanos TP, Csorba BA, Pilly PK, Choe J, Phillips ME, Datta A, Pack CC (2017) Transcranial direct current stimulation facilitates associative learning and alters functional connectivity in the primate brain. Curr Biol 27(20):3086\u20133096 e3083. \n                    https:\/\/doi.org\/10.1016\/j.cub.2017.09.020","journal-title":"Curr Biol"},{"key":"8993_CR50","doi-asserted-by":"publisher","first-page":"710","DOI":"10.3389\/fnins.2017.00710","volume":"11","author":"M Stampanoni Bassi","year":"2017","unstructured":"Stampanoni Bassi M, Gilio L, Buttari F, Maffei P, Marfia GA, Restivo DA, Centonze D, Iezzi E (2017) Remodeling functional connectivity in multiple sclerosis: a challenging therapeutic approach. Front Neurosci 11:710. \n                    https:\/\/doi.org\/10.3389\/fnins.2017.00710","journal-title":"Front Neurosci"}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00415-018-8993-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-018-8993-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-018-8993-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,5]],"date-time":"2019-08-05T19:07:17Z","timestamp":1565032037000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00415-018-8993-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,6]]},"references-count":50,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["8993"],"URL":"https:\/\/doi.org\/10.1007\/s00415-018-8993-6","relation":{},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,6]]},"assertion":[{"value":"16 June 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 July 2018","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 July 2018","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 August 2018","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All authors declare no support from any organization for the submitted work, no financial relationships with any organizations that might have an interest in the submitted work, and no other relationships or activities that could appear to have influenced the submitted work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Ethics approval was provided by the institutional ethical standards committee on human experimentation at the University of Leipzig (371\/14-ek). All participants provided written informed consent before the conduct of any study-related procedures.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standard"}}]}}