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Rezende reports grants from FAPESP; Dr Faber reports grants from CNPq (Brazilian National Council for Scientific and -Technological Development) during the conduct of the study; Dr Martinez reports grants from FAPESP during the conduct of this study; Dr Lopes-Cendes reports grants from FAPESP and CNPq, during the conduct of the study. Dr Fran\u00e7a Jr reports grants from FAPESP and CNPq. Dr Barsottini reports grants from FAPESP and CNPq, during the conduct of the study. Dr Pedroso reports grants from FAPESP and CNPq, during the conduct of the study. The authors declare that they have no conflict of interest. Marcondes C Fran\u00e7a Jr: reports grants from FAPESP during the conduct of this study. He also\u00a0received research support from PTC therapeutics, Crist\u00e1lia and Pfizer; took part in advisory boards for Genzyme, Pfizer, Baxter and CSL-Behring; Received travel Grant from Pfizer, Baxter and PTC therapeutics.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}