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Jan Claudius Schwitalla has no conflict of interest. Frank Diesner has no conflict of interest. Hans-Peter Hartung received, with approval of the Rector of Heinrich-Heine-University and the CEO of University of D\u00fcsseldorf Hospital honoraria for consulting, serving on steering committees and speaking from Biogen, CSL Behring, Geneuro, Genzyme, LFB, Medimmune, Merck, Novartis, Octapharma, Opexa, Receptos\/Celgene, Roche, Sanofi, and Teva. Orhan Aktas received, with approval of the Rector of Heinrich-Heine-University, grants from the German Research Foundation (DFG), the German Ministry for Education and Research (BMBF) as part of the German Competence Network Multiple Sclerosis (KKNMS; for NEMOS NationNMO-PAT FKZ 01GI1602B), the Eug\u00e8ne Devic European Network (EU-FP7), honoraria and travel\/accommodation\/meeting expenses from Almirall, Bayer, Biogen, Medimmune, Merck Serono, Novartis, Roche, Sanofi-Genzyme, and Teva. 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