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Jazz Pharmaceuticals also reviewed the manuscript and had the opportunity to provide suggestions to the authors for their consideration. Although Jazz Pharmaceuticals reviewed the content of this manuscript, the ultimate interpretation, and the decision to submit it for publication was made by the authors independently. \u201cJazz pharmaceuticals holds a royalty-bearing non-exclusive license to the SNS from the University of Bern\u201d. <i>Panagiotis Bargiotas<\/i> has no specific conflict of interest with respect of present work. Dr. Bargiotas has received congress fees and travel reimbursements from Lundbeck Foundation. <i>Anelia Dietmann, Marta Garcia Calle, Markus Schmidt, and Johannes Mathis<\/i> have no specific conflict of interest with respect of present work and have nothing to declare. <i>Alan G. Haynes<\/i> is affiliated with CTU Bern, University of Bern, which has a staff policy of not accepting honoraria or consultancy fees. However, CTU Bern is involved in design, conduct, or analysis of clinical studies funded by not-for-profit and for-profit organizations. In particular, pharmaceutical and medical device companies provide direct funding to some of these studies. For an up-to-date list of CTU, Bern\u2019s conflicts of interest see \u201c\n                      \n                      \u201d. <i>Ulf Kallweit<\/i> has received Honoraria for consultancy\/advisory board and\/or speaking engagements from: AOP Orphan Pharma; Bioprojet Pharma; Harmony Biosciences; Jazz Pharma; UCB Pharma. <i>Claudio Bassetti<\/i> has no specific conflict of interest with respect of present work. Prof. Bassetti has received honoraria for consultancy, lectures, and board memberships from the following institutions\/companies: Jazz, Servier, UCB, Zambon, Cephalon Lundbeck, Pfizer Bohringer Ingelheim. His research is currently supported by grants of the following institutions\/companies: Swiss National Science Foundation (SNF), ResMed, Respironics, Vifor Pharma, UCB Pharma, Schweizerische Herzstiftung, Tropos Stiftung, Parkinson Schweiz.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}