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M. Goeldlin\u2019s work is supported by a \u201cYoung Talents in Clinical Research\u201d Grant by the SAMW\/Bangerter-Rhyner foundation (Grant YTCR_13\/18). Dr. Bernasconi has received consulting fees from Roche, Santhera, AC Immune and PresSura Neuro. Dr. Kalla and Dr. Mantokoudis were supported by the Swiss National Science Foundation (Grant #320030_173081). Dr. Fischer is a consultant for Medtronic, Stryker and CSL Behring. He is the Co-PI of the SWIFT DIRECT trial (supported by Medtronic). He receives research grants from the Swiss Heart Foundation and the Swiss National Science Foundation.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"\u00a0The study was approved by the local ethics committee and was conducted in accordance with the Declaration of Helsinki. Given the retrospective nature of the study, informed consent was provided through a hospital-wide general consent. 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